Title: Book the Best Kearny Mesa LUXURY Hotels - Upscale Hotels in Kearny Mesa, San Diego | Expedia.ca [Kearny Mesa Travel Guide](https://expedia.ca/San-Diego-Kearny-Mesa.dx3000663380)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Kearny Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Kearny-Mesa.d3000663380.Car-Rental-Guide)[Kearny Mesa Vacations](https://expedia.ca/Kearny-Mesa.d3000663380.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/61ed2227da885283bd87ee121b1d0e38.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Kearny Mesa, San Diego ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Kearny Mesa Luxury Hotels Tonight [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-01&endDate=2025-10-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-02&endDate=2025-10-03&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Kearny Mesa Luxury Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/804dc72b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/44881788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/e2b8ef1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/584e67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Hotel & Conference Center by Wyndham San Diego North Kearny Mesa 8.0/10 Very good (942) [](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d216d27d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/ece284b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/67dab677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d09e0109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton San Diego Kearny Mesa 8.0/10 Very good (1000) "Beautiful location. My go to hotel when I visit family if I cant stay at their residence." CA $181 CA $208 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego.h23651.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/b459e7de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/df5e87a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/1e392c1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/4438ee0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Central Kearny Mesa 8.6/10 Excellent (1011) "Close shopping area, great and comfortable bedding. " CA $182 CA $209 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-15&endDate=2025-10-16®ionId=3000663380&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Kearny Mesa Hotel Reviews ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "The place was well maintained and very clean. Unfortunately, its very close to a major highway and it can be noisy. At least, in the room i stayed in, which was parallel to the street. " [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![San Diego Marriott La Jolla](//images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Great location right by the freeway, and there is a mall within walking distance" [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Great calm place" [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Room was great! Tile in bathroom was dirty. Sink did not function, front desk was notified. Otherwise a great stay, I'll be back" [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Brilliant Atmosphere, all perfect." [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Perfect stay" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Great " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Courtyard by Marriott San Diego Central](//images.trvl-media.com/lodging/1000000/860000/854500/854424/b459e7de_y.jpg) ### Courtyard by Marriott San Diego Central 10/10 Excellent "Free tesla charging" [](https://expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](//images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Loved area convenient and very safe! " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury trip to Kearny Mesa? > Use Expedia to help you arrange a flight to San Diego, CA (MYF-Montgomery Field) airport or San Diego Intl. Airport (SAN) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay special. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Kearny Mesa has to offer. During your visit, you might want to enjoy the restaurants and beer bars which Kearny Mesa is known for. ### What's there to see and do in Kearny Mesa? > When you're in Kearny Mesa, enjoy exploring the sights and attractions here including Mission Bay, San Diego Zoo, and Marine Corps Recruit Depot. 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