Title: Book the Best Kearny Mesa LUXURY Hotels - Upscale Hotels in Kearny Mesa, San Diego | Expedia.ca [Kearny Mesa Travel Guide](https://expedia.ca/San-Diego-Kearny-Mesa.dx3000663380)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Kearny Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Kearny-Mesa.d3000663380.Car-Rental-Guide)[Kearny Mesa Vacations](https://expedia.ca/Kearny-Mesa.d3000663380.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Kearny Mesa, San Diego - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Kearny Mesa Luxury Hotels Tonight [Nov 7 - Nov 8](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-11-07&endDate=2025-11-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 8 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-11-08&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Kearny Mesa Luxury Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/804dc72b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/d2021e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/f581bd3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch TV with cable channels](https://images.trvl-media.com/lodging/1000000/30000/27900/27878/c8cac925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Hotel & Conference Center by Wyndham San Diego North Kearny Mesa 8.0/10 Very good (942) "Very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/San-Diego-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-San-Diego-North.h27878.Hotel-Information) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d216d27d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/ece284b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/67dab677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/845c0385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton San Diego Kearny Mesa 8.0/10 Very good (1001) "Overall, I had a great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph Payne Williams, CA $185 CA $212 total includes taxes & fees Nov 22 - Nov 23 [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego.h23651.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/b459e7de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/e043babb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/1e392c1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/4438ee0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Central Kearny Mesa 8.6/10 Excellent (1027) "Wonderful stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chisomo CA $185 CA $212 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-21&endDate=2025-11-22®ionId=3000663380&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Kearny Mesa Hotel Reviews ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Didn't eat breakfast there so can't say much, but the room was clean to my liking " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Easy check in/out. Clean rooms. Near everything we needed " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "One of the best venues I stayed. Curteous staff, clean rooms, complimentary drinks." [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "All went pretty well" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Sheraton Mission Valley San Diego Hotel](//images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Staff were incredibly friendly and welcoming, especially Victor at the front desk. The room was spotless and immaculate, thanks to the efforts of Tomasa. The room was very comfortable, although the bathroom was a bit on the small side. My room facing the mountain was very quiet. All in all, this was a great stay and I'd happily choose to stay here again. " [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](//images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "I refer to the restaurant as the "Chum Bucket". It is a small afterthought aside from the lobby. The place has maybe a smaller menu than a Del Mar roach coach." [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "The room and service was excellent. " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Clean room, friendly staff, and great service." [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Comfort Inn Sea World Area](//images.trvl-media.com/lodging/1000000/550000/544700/544662/44f458a2_y.jpg) ### Comfort Inn Sea World Area 10/10 Excellent "Very clean rooms and very accessible. Loved it." [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-Sea-World-Area.h544662.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury trip to Kearny Mesa? > Use Expedia to help you arrange a flight to San Diego, CA (MYF-Montgomery Field) airport or San Diego Intl. Airport (SAN) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay special. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Kearny Mesa has to offer. During your visit, you might want to enjoy the restaurants and beer bars which Kearny Mesa is known for. ### What's there to see and do in Kearny Mesa? > When you're in Kearny Mesa, enjoy exploring the sights and attractions here including Mission Bay, San Diego Zoo, and Marine Corps Recruit Depot. 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