Title: Book the Best BUSINESS Hotels in Kearny Mesa in 2025 | Expedia.ca [Kearny Mesa Travel Guide](https://expedia.ca/San-Diego-Kearny-Mesa.dx3000663380)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Kearny Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Kearny-Mesa.d3000663380.Car-Rental-Guide)[Kearny Mesa Vacations](https://expedia.ca/Kearny-Mesa.d3000663380.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/61ed2227da885283bd87ee121b1d0e38.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Kearny Mesa, CA from CA $100 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Kearny Mesa Business Hotels Tonight [Oct 3 - Oct 4](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-03&endDate=2025-10-04&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 4 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-04&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3000663380&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Kearny Mesa Business Hotels ![Economy Single Room, 2 Double Beds](https://images.trvl-media.com/lodging/3000000/2330000/2322400/2322323/851b79cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2330000/2322400/2322323/f8df0f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2330000/2322400/2322323/d6211962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2330000/2322400/2322323/19534369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Mediteran Escondido Kit Carson 8.8/10 Excellent (1002) "Staff was very efficient, quick and easy check in" CA $90 CA $100 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Escondido-Hotels-Motel-Mediteran-Escondido.h2322323.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/3ced364d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/ff230e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/69474629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/3c739431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ayres Hotel San Diego South - Chula Vista Otay Ranch 9.8/10 Exceptional (1086) "The staff were friendly, clean rooms, and conveniently located to shops and places to eat " CA $169 CA $186 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Chula-Vista-Hotels-Ayres-Hotel-San-Diego-South-Chula-Vista.h32393708.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/1000000/20000/18800/18737/4fe0c2fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/18800/18737/0ed1119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/18800/18737/0298d2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/20000/18800/18737/a2043b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Encinitan Hotel & Suites Encinitas 8.0/10 Very good (1206) "Great stay" CA $153 CA $190 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Encinitas-Hotels-Best-Western-Encinitas-Inn-Suites-At-Moonlight-Beach.h18737.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/ddcd0247.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/291cfcc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/aeccf49c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/w3839h2549x0y5-2be78d7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn San Diego-Kearny Mesa Kearny Mesa 9.0/10 Wonderful (1000) "Short but sweet, a great stay" CA $178 CA $204 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Kearny-Mesa.h8604.Hotel-Information) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d216d27d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/67dab677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/ece284b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d09e0109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton San Diego Kearny Mesa 8.0/10 Very good (1000) "Beautiful location. My go to hotel when I visit family if I cant stay at their residence." CA $194 CA $223 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego.h23651.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/cc4647fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/8fb13e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/0f7253f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/9a0a7909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn San Diego Mission Valley Stadium Kearny Mesa 8.0/10 Very good (1001) "Great location. " CA $171 CA $196 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-Garden-Inn-San-Diego-Mission-Valley-Stadium.h13145727.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/b459e7de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/df5e87a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/e043babb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/860000/854500/854424/4438ee0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Central Kearny Mesa 8.6/10 Excellent (1000) "Close shopping area, great and comfortable bedding. " CA $195 CA $224 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/880000/876900/876828/7353f65a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/876900/876828/ceae6eb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed, Accessible, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/1000000/880000/876900/876828/6aa5eae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/880000/876900/876828/1b00818f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Suites San Diego Mission Valley Stadium Kearny Mesa 6.4/10 (1000) "I'm always pleased by this hotel definitely will be back. " CA $136 CA $156 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/San-Diego-Hotels-Extended-Stay-America-Suites-San-Diego-Mission-Valley-Stadiu.h876828.Hotel-Information) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/1f4c359a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/7910f1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort El Cajon 9.2/10 Wonderful (1557) "Great resort!" CA $161 CA $194 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/49f2cd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/4b32319c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/e913facd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/5700/5684/0d512cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego - Miramar Rancho Peñasquitos 7.6/10 Good (1028) "Staff was friendly and very inviting. Would definitely stay here again. " CA $118 CA $136 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/San-Diego-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Miramar.h5684.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-17&endDate=2025-10-18®ionId=3000663380&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Kearny Mesa Hotel Reviews ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Stay was excellent room always cleaned and beds made promptly. Room was very spacious and view of the bay with balcony amazing. Location is excellent." [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Hotel is pretty and is in a great location to be able to walk to shops, restaurants and bars " [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "It was centrally located,. I had private car and they had parking in. It was perfect for me, the rooms were comfortable and clean. Pretty view." [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean room" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Thanks " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "We stayed for 9 nights and had an awesome time! Staff was friendly and accommodating. " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Great ocean view located right on wide beach. Hotel is awesome." [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The Manchester Grand Hyatt is our go to hotel in San Diego due to its convenient location by the Seaport Village and many restaurants and shops. We have stayed there several times and always enjoy the scenic views from our room and the hospitality of the hotel staff. The breakfast buffet has a large variety of offerings including an omelette station. The MarketOne Cafe downstairs has many items including delicious pastries and other food and drink items. It is always a great experience to stay at the Manchester Grand Hyatt in San Diego." [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "the hotel was very clean and the front desk was very friendly" [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Kearny Mesa with Expedia? > At Expedia, our top task is to help you find the perfect stay at the right price. From upmarket, corporate-friendly escapes to affordable hotels loaded with amenities, you'll have your next work trip booked in a couple of clicks. ### How can I find cheap business-friendly hotels in Kearny Mesa? > When work takes you on the road in Kearny Mesa, our "business friendly" filter will help you find the right hotel. From free WiFi to concierge services and conference spaces, they have the amenities you need to get down to business. Another tip? 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