Title: Book the Best BUSINESS Hotels in Johns Island in 2026 | Expedia.ca [Johns Island Travel Guide](https://expedia.ca/Johns-Island.dx603232)[Hotels in Johns Island](https://expedia.ca/Johns-Island-Hotels.d603232.Travel-Guide-Hotels)[Vacation Rentals in Johns Island](https://expedia.ca/Johns-Island-Vacation-Rentals.d603232.Travel-Guide-VacationRentals)[Johns Island Car Rentals](https://expedia.ca/Car-Rentals-In-Johns-Island.d603232.Car-Rental-Guide)[Johns Island Vacation Packages](https://expedia.ca/Johns-Island.d603232.Destination-Travel-Guides) ![This ten mile section of S-10-20 in Charleston County is located on Johns Island in lower Charleston County. It includes historical, recreational and agricultural sites. It is home to Angel Oak, a southern live oak tree thought to be over 400 years old. With the development of Kiawah and Seabrook Islands, this route has become a busy thoroughfare, but the intrinsic beauty of the road remains.](https://images.trvl-media.com/place/603232/86765bb5-4257-47a5-b3d3-1c478de0e1ca.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by William Keller ![](https://images.trvl-media.com/place/603232/86765bb5-4257-47a5-b3d3-1c478de0e1ca.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Johns Island Business Hotels Tonight [Jan 20 - Jan 21](https://www.expedia.ca/Hotel-Search?regionId=603232&startDate=2026-01-20&endDate=2026-01-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 21 - Jan 22](https://www.expedia.ca/Hotel-Search?regionId=603232&startDate=2026-01-21&endDate=2026-01-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=603232&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=603232&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Johns Island business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/3000000/2280000/2279600/2279569/dace95e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2280000/2279600/2279569/840af564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2280000/2279600/2279569/154dcf09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2280000/2279600/2279569/4c7772c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place North Charleston [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-North-Charleston.h2279569.Hotel-Information) North Charleston 8.4/10 Very good (1,019 reviews) "Rooms were spacious and clean. Staff was super nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jasmine CA $122 CA $139 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-North-Charleston.h2279569.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772021/0badcc83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772021/6d704b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772021/c4c6a58c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772021/3135f110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites North Charleston - Northwoods [](https://www.expedia.ca/North-Charleston-Hotels-Comfort-Inn-Suites-North-Charleston-Northwoods.h1772021.Hotel-Information) North Charleston 8.2/10 Very good (1,013 reviews) "Clean Room , Nice Staff Easy Check On" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jermaine CA $111 CA $127 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/North-Charleston-Hotels-Comfort-Inn-Suites-North-Charleston-Northwoods.h1772021.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17700/17658/e65be6e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/17700/17658/dadba882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/17700/17658/78e98ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/17700/17658/b46e4cc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Charleston Riverview [](https://www.expedia.ca/Charleston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Charleston-Riverview.h17658.Hotel-Information) West Ashley 6.4/10 (2,584 reviews) "Great staff, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) zachary CA $79 CA $90 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Charleston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Charleston-Riverview.h17658.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/41000000/40850000/40845500/40845414/43529248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/41000000/40850000/40845500/40845414/c323a7a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/41000000/40850000/40845500/40845414/0453e814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/41000000/40850000/40845500/40845414/fbb89135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Charleston Ashley Phosphate [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Charleston-Ashley-Phosphate.h40845414.Hotel-Information) North Charleston 9.2/10 Wonderful (1,221 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sabrina CA $118 CA $135 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Charleston-Hotels-Tru-By-Hilton-Charleston-Ashley-Phosphate.h40845414.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/39000000/38510000/38507500/38507457/bfb7c245.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/39000000/38510000/38507500/38507457/4059913d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/39000000/38510000/38507500/38507457/a6cfa162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed (Hearing Accessible) | Living room](https://images.trvl-media.com/lodging/39000000/38510000/38507500/38507457/70362c9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Charleston-North Charleston [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-North-Charleston.h38507457.Hotel-Information) Ashley Heights 8.8/10 Excellent (1,006 reviews) "Rooms were clean and the staff was so nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy CA $128 CA $149 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Charleston-Hotels-Courtyard-By-Marriott-Charleston-North-Charleston.h38507457.Hotel-Information) ![Dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/abd17d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/a5693308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Corner King Suite with Sofa Bed](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/c632a24f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/25000000/24220000/24216500/24216478/247bf02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Mount Pleasant – Charleston [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) Mount Pleasant 9.4/10 Exceptional (1,871 reviews) "Excellent stay in Charleston! Great staff great location and VERY clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $136 CA $155 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Charleston-Hotels-Cambria-Hotel-Mount-Pleasant-Charleston.h24216478.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58150000/58147700/58147634/4bcc03d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58150000/58147700/58147634/90de7500.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed](https://images.trvl-media.com/lodging/59000000/58150000/58147700/58147634/07fd844c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58150000/58147700/58147634/b7f3f3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Charleston Airport & Convention Center [](https://www.expedia.ca/Charleston-Hotels-SpringHill-Suites-By-Marriott-Charleston-Airport-Convention-Center.h58147634.Hotel-Information) North Charleston 9.4/10 Exceptional (1,005 reviews) "Staff was amazing at check in and breakfast was also well staffed and very friendly. Will stay here every time I’m in the area. Also very short walk to the convention center. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy CA $123 CA $141 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Charleston-Hotels-SpringHill-Suites-By-Marriott-Charleston-Airport-Convention-Center.h58147634.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/16200/16158/1b66db9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16200/16158/9b84ccae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/16200/16158/bafbce3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16200/16158/8fa5be7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Hotel & Suites Charleston Airport [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Hotel-And-Suites-Charleston-Airport.h16158.Hotel-Information) North Charleston 8.4/10 Very good (1,002 reviews) "Nice rooms great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $114 CA $130 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Charleston-Hotels-DoubleTree-By-Hilton-Hotel-And-Suites-Charleston-Airport.h16158.Hotel-Information) ![Deluxe Room, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/210000/203700/203666/2072a841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203666/a4e35520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203666/d8131a73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203666/75cd7616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Charleston-North [](https://www.expedia.ca/North-Charleston-Hotels-Hampton-Inn-Charleston-North.h203666.Hotel-Information) Ashley Heights 9.0/10 Wonderful (1,008 reviews) "The staff were incredibly helpful and friendly. Would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judy CA $118 CA $134 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/North-Charleston-Hotels-Hampton-Inn-Charleston-North.h203666.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/87b27d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/581d948f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/b2c4a3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913928/d9fde6a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) Mount Pleasant 9.0/10 Wonderful (1,006 reviews) "Hotel was clean and comfortable. Staff was very friendly, polite and accommodating. Breakfast was good just need more options. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $117 CA $132 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Suites-Charleston-NE-Mt-Pleasant-US17.h15913928.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04®ionId=603232&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Johns Island Hotel Reviews ![The Ansonborough](https://images.trvl-media.com/lodging/1000000/920000/914600/914563/9e20e2b9_y.jpg) ### The Ansonborough 10/10 Excellent "Manny, the bartender, was wonderful! He made great drinks, especially Espresso Martinis! The best espresso martini in Charleston!" [](https://expedia.ca/Charleston-Hotels-Ansonborough-Inn.h914563.Hotel-Information) ![Planters Inn](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/c138e1de_y.jpg) ### Planters Inn 10/10 Excellent "Roooms were cool vintage charleston vibes. Hotel was nice and bathrooms were clean and updated. Parking isnt great and just ended up doing valet." [](https://expedia.ca/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 10/10 Excellent "Loved this property!" [](https://expedia.ca/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![Harborside at Charleston Harbor Resort and Marina](https://images.trvl-media.com/lodging/1000000/70000/67700/67652/0212aa65_y.jpg) ### Harborside at Charleston Harbor Resort and Marina 10/10 Excellent "This is the best place to stay in the Charleston area. " [](https://expedia.ca/Charleston-Hotels-Harborside-At-Charleston-Harbor-Resort-And-Marina.h67652.Hotel-Information) ![Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG](https://images.trvl-media.com/lodging/1000000/10000/7500/7488/dd901663_y.jpg) ### Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG 10/10 Excellent "We arrived at midnight (January 9-10). The front desk was most helpful. Throughout our short stay, I have to stay every staff member we encountered was so pleasant and helpful. The breakfast variety was a nice touch as well. This is surely a hotel I would return to for a quick get away!" [](https://expedia.ca/Charleston-Hotels-Holiday-Inn-Express-Charleston-Dwtn-Medical-Area.h7488.Hotel-Information) ![Hyatt Place Charleston/Historic District](https://images.trvl-media.com/lodging/11000000/10520000/10519900/10519812/b130f925_y.jpg) ### Hyatt Place Charleston/Historic District 10/10 Excellent "The staff were great and helpful. The rooftop bar was a great place to hang out. " [](https://expedia.ca/Charleston-Hotels-Hyatt-Place-CharlestonHistoric-District.h10519812.Hotel-Information) ![The Beach Club at Charleston Harbor Resort and Marina](https://images.trvl-media.com/lodging/14000000/13200000/13199200/13199113/c2fc6e8d_y.jpg) ### The Beach Club at Charleston Harbor Resort and Marina 10/10 Excellent "Love it ! We've been 3 times now and it's always great " [](https://expedia.ca/Charleston-Hotels-The-Beach-Club-At-Charleston-Harbor-Resort-And-Marina.h13199113.Hotel-Information) ![The Charleston Place](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/4a7de88d_y.jpg) ### The Charleston Place 10/10 Excellent "The staff are very professional, courteous and super keen to assist in any way possible. The room was clean and comfortable. Loved the central location. " [](https://expedia.ca/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/d17025e1_y.jpg) ### Emeline 10/10 Excellent "Beautiful spot with tons of unique details " [](https://expedia.ca/Charleston-Hotels-Emeline.h8890.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [3 Star Hotels in Vanderhorst Plantation ](https://www.expedia.ca/3Star-Vanderhorst-Plantation-Kiawah-Island-Hotels.s30-n553248635976471182-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Folly Beach ](https://www.expedia.ca/4Star-Folly-Beach-Hotels.s40-0-d7217.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Folly Beach ](https://www.expedia.ca/5Star-Folly-Beach-Hotels.s50-0-d7217.Travel-Guide-Filter-Hotels) - [Hotels near Angel Oak Tree ](https://www.expedia.ca/Angel-Oak-Tree-Hotels.0-l6335592-0.Travel-Guide-Filter-Hotels) - [Business Hotels in Charleston ](https://www.expedia.ca/Charleston-Hotels-Business-Hotel.0-0-d179997-tBusinessHotel.Travel-Guide-Filter-Hotels) - 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