Title: Book the Best BUSINESS Hotels in Jeffersonville in 2026 | Expedia.ca [Hotels in Jeffersonville](https://expedia.ca/Jeffersonville-Hotels.d8031.Travel-Guide-Hotels)[Vacation Rentals in Jeffersonville](https://expedia.ca/Jeffersonville-Vacation-Rentals.d8031.Travel-Guide-VacationRentals)[Flights to Jeffersonville](https://expedia.ca/Cheap-Flights-To-Jeffersonville.d8031.Travel-Guide-Flights)[Jeffersonville Car Rentals](https://expedia.ca/Car-Rentals-In-Jeffersonville.d8031.Car-Rental-Guide)[Jeffersonville Vacation Packages](https://expedia.ca/Jeffersonville.d8031.Destination-Travel-Guides) ![Louisville, Kentucky; Shutterstock ID 361332](https://images.trvl-media.com/place/8031/dab9be60-abe6-4512-9e33-fce27f42b078.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Jeffersonville, IN from CA $103 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Jeffersonville Business Hotels Tonight [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=8031&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=8031&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=8031&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=8031&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Jeffersonville business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/a3e348c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/60d38477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/74f4d732.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76420000/76418000/76417931/b6561da4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Jeffersonville Louisville North [](https://www.expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Jeffersonville.h76417931.Hotel-Information) Jeffersonville 9.6/10 Exceptional (401) "The staff was very friendly and helpful. The facility was clean, safe and well maintained. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bianca CA $142 CA $161 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Jeffersonville.h76417931.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/57000000/56540000/56532400/56532339/0fae1e88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/57000000/56540000/56532400/56532339/2209f9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56540000/56532400/56532339/dc8aac5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56540000/56532400/56532339/a8925e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Louisville Jeffersonville [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Jeffersonville.h56532339.Hotel-Information) Jeffersonville 8.8/10 Excellent (141) "The rooms were clean and the man who worked the front desk was great! We will definitely look to stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyler CA $136 CA $153 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Louisville-Hotels-Fairfield-Inn-Suites-By-Marriott-Louisville-Jeffersonville.h56532339.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/58000000/57370000/57361000/57360996/36596159.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/58000000/57370000/57361000/57360996/3991db12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/58000000/57370000/57361000/57360996/58a90a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/58000000/57370000/57361000/57360996/bf59cd30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Louisville N - Jeffersonville by IHG [](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-N-Jeffersonville.h57360996.Hotel-Information) Jeffersonville 8.8/10 Excellent (408) "The rooms were perfectly clean and every staff member was very nice to our group!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jade CA $122 CA $138 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-N-Jeffersonville.h57360996.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/21000000/20180000/20177600/20177563/2010f6e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/21000000/20180000/20177600/20177563/09d6f2f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/21000000/20180000/20177600/20177563/33398e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/21000000/20180000/20177600/20177563/8b1c7bc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Louisville North [](https://www.expedia.ca/Louisville-Hotels-TownePlace-Suites-By-Marriott-Louisville-North.h20177563.Hotel-Information) Jeffersonville 9.2/10 Wonderful (640) "Best hotel and staff ever " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $140 CA $158 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Louisville-Hotels-TownePlace-Suites-By-Marriott-Louisville-North.h20177563.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/2f87d903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed with Sofa bed, River View | Living area](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/07df0365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/f2e3b357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Louisville Riverside by Marriott [](https://www.expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information) Jeffersonville 8.2/10 Very good (1000) "Enjoyed staying in this hotel. Very polite and helpful staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $105 CA $119 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513760/dbde1484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513760/1a447c4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513760/432b72fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513760/33f7c3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Suites Jeffersonville - Louisville North [](https://www.expedia.ca/Louisville-Hotels-Quality-Suites.h1513760.Hotel-Information) Jeffersonville 7.4/10 Good (576) "mostly very good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) THOMAS CA $110 CA $125 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Louisville-Hotels-Quality-Suites.h1513760.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/46279487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/a276c9db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/ce1b7eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9680000/9678400/9678336/76841ca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Market Street Inn [](https://www.expedia.ca/Louisville-Hotels-Market-Street-Inn.h9678336.Hotel-Information) Jeffersonville 9.8/10 Exceptional (120) "I enjoyed my stay, however the breakfast portion was very small even for a petite person like myself, I was still very hungry after breakfast. There was a cleaning issue with the bathroom that was overlooked by the cleaning staff that I alerted the owners to that will hopefully be fixed for future visitors. The house is great and very clean overall. The owners are very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan CA $255 CA $289 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Louisville-Hotels-Market-Street-Inn.h9678336.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1940000/1938600/1938560/f38836bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1940000/1938600/1938560/cd90c609.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop](https://images.trvl-media.com/lodging/2000000/1940000/1938600/1938560/571a9d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/2000000/1940000/1938600/1938560/9d7a0a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Louisville Clarksville [](https://www.expedia.ca/Louisville-Hotels-WoodSpring-Suites-Louisville-Clarksville.h1938560.Hotel-Information) Jeffersonville 5.6/10 (591) "Roaches everywhere, people standing by cars all night" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachele CA $91 CA $103 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Louisville-Hotels-WoodSpring-Suites-Louisville-Clarksville.h1938560.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/w3839h2492x0y0-b699260c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/a9510c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/4171bcac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/w3836h2489x0y0-683f8c6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Simpsonville [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Simpsonville.h31356812.Hotel-Information) Simpsonville 9.4/10 Exceptional (901) "Would stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $121 CA $134 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Simpsonville.h31356812.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/35000000/34190000/34182600/34182534/b8746465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34190000/34182600/34182534/808f802e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/35000000/34190000/34182600/34182534/576ae0f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34190000/34182600/34182534/b64b0e0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites La Grange by IHG [](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-And-Suites-La-Grange.h34182534.Hotel-Information) La Grange 9.0/10 Wonderful (766) "Great staff very clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DAVID CA $135 CA $153 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-And-Suites-La-Grange.h34182534.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-25&endDate=2025-12-26®ionId=8031&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Jeffersonville Hotel Reviews ![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Don't charge for breakfast" [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Hawthorn Suites by Wyndham Louisville East](https://images.trvl-media.com/lodging/1000000/890000/890000/889990/00fe98fb_y.jpg) ### Hawthorn Suites by Wyndham Louisville East 10/10 Excellent "Room was impressive, especially for that price range. Room was impeccable and the furniture looked new. Only complaint I have was the exercise room where the machines weren't working. " [](https://expedia.ca/Louisville-Hotels-Hawthorn-Suites-By-Wyndham-Louisville-East.h889990.Hotel-Information) ![Sheraton Louisville Riverside by Marriott](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg) ### Sheraton Louisville Riverside by Marriott 10/10 Excellent "Room clean and staff friendly" [](https://expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information) ![Radisson Hotel Louisville North](https://images.trvl-media.com/lodging/1000000/30000/26400/26306/50b82654_y.jpg) ### Radisson Hotel Louisville North 10/10 Excellent "The staff was great and the amenities were great." [](https://expedia.ca/Louisville-Hotels-Radisson-Hotel-Louisville-North.h26306.Hotel-Information) ![Hilton Garden Inn Louisville/Northeast](https://images.trvl-media.com/lodging/3000000/2050000/2041500/2041424/b2a28346_y.jpg) ### Hilton Garden Inn Louisville/Northeast 10/10 Excellent "Everything was great " [](https://expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Louisville-Northeast.h2041424.Hotel-Information) ![Holiday Inn Express & Suites Louisville Downtown by IHG](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/380612f2_y.jpg) ### Holiday Inn Express & Suites Louisville Downtown by IHG 10/10 Excellent "Nice place " [](https://expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information) ![Hilton Garden Inn Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9220000/9215400/9215348/d064e9c8_y.jpg) ### Hilton Garden Inn Louisville Downtown 10/10 Excellent "Clean and convenient " [](https://expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Louisville-Downtown.h9215348.Hotel-Information) ![Crowne Plaza Louisville Airport Expo Ctr by IHG](https://images.trvl-media.com/lodging/1000000/20000/11400/11386/a43a56f2_y.jpg) ### Crowne Plaza Louisville Airport Expo Ctr by IHG 10/10 Excellent "Very nice and helpful staff. Delicious breakfast. " [](https://expedia.ca/Louisville-Hotels-Crowne-Plaza-Louisville-Airport-Expo-Center.h11386.Hotel-Information) ![The Brown Hotel](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de_y.jpg) ### The Brown Hotel 10/10 Excellent "The staff was very attentive, great folks. The hotel and rooms were gorgeous. If you’re coming to Louisville, pass on the chain hotels and stay at The Brown, you won’t be disappointed. " [](https://expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Jeffersonville cost? ### What are the best business-friendly hotels in Jeffersonville? ### How many business-friendly hotels are there in Jeffersonville? ### What are the best cheap business-friendly hotels in Jeffersonville? ### What are the top business-friendly motels in Jeffersonville? ### Are there any family-friendly hotels in Jeffersonville that are also business friendly? ### Are there any 5-star business-friendly hotels in Jeffersonville? ### Why book your business-friendly hotel in Jeffersonville with Expedia? ### How can I find cheap business-friendly hotels in Jeffersonville? ### What is there to do in Jeffersonville near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [5 Star Hotels in Duncan ](https://www.expedia.ca/5Star-Duncan-Georgetown-Hotels.s50-n553248635975849362-0.Travel-Guide-Filter-Hotels) - 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