Title: Book the Best Jeffersonville - Clarksville SPA Resorts - Spa Hotels in Jeffersonville - Clarksville, IN | Expedia.ca [Jeffersonville - Clarksville Travel Guide](https://expedia.ca/Jeffersonville-Clarksville.dx6059638)[Hotels in Jeffersonville - Clarksville](https://expedia.ca/Jeffersonville-Clarksville-Hotels.d6059638.Travel-Guide-Hotels)[Vacation Rentals in Jeffersonville - Clarksville](https://expedia.ca/Jeffersonville-Clarksville-Vacation-Rentals.d6059638.Travel-Guide-VacationRentals)[Flights to Jeffersonville - Clarksville](https://expedia.ca/Cheap-Flights-To-Jeffersonville-Clarksville.d6059638.Travel-Guide-Flights)[Jeffersonville - Clarksville Car Rentals](https://expedia.ca/Car-Rentals-In-Jeffersonville-Clarksville.d6059638.Car-Rental-Guide)[Jeffersonville - Clarksville Vacation Packages](https://expedia.ca/Jeffersonville-Clarksville.d6059638.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/55a2a839cfa643987144c792847283db.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Jeffersonville - Clarksville, IN ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Jeffersonville - Clarksville Spa Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6059638&startDate=2025-10-15&endDate=2025-10-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6059638&startDate=2025-10-16&endDate=2025-10-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6059638&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6059638&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Jeffersonville - Clarksville Spa Hotels ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/2339d325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana - A Caesars Rewards Destination Elizabeth 8.2/10 Very good (1014) "Easy parking, Very friendly/helpful staff, easy check in/out, Nice casino, Good food options" CA $85 CA $122 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham Downtown Louisville 9.0/10 Wonderful (3697) "Great place to stay" CA $192 CA $226 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville Downtown Louisville 9.4/10 Exceptional (1004) "Great stay overall. " CA $239 CA $288 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/w5757h3840x3y0-b0a2f211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel Downtown Louisville 9.2/10 Wonderful (1648) "Great stay" CA $280 CA $329 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/9cc68008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Apartment, 1 King Bed with Sofa bed, Kitchenette, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/46f16aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Multiple Beds, Kitchenette, Garden View | Living area](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/3fd39b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/82066f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pillow and Paddock B&B La Grange 10/10 Exceptional (50) "This has been our second time staying here and we will continue to come back. Beautiful home, amazing breakfasts, and wonderful hosts, not much else we could ask for. " CA $326 CA $360 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=6059638&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Jeffersonville - Clarksville Hotel Reviews ![Galt House Hotel Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Room and service was amazing. Easy to get to and plenty to do in the area. Will definitely be our go to hotel when we travel to Louisville for here on out. " [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Caesars Southern Indiana](//images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc_y.jpg) ### Caesars Southern Indiana 10/10 Excellent "Very quiet " [](https://expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![Courtyard by Marriott Louisville Airport](//images.trvl-media.com/lodging/1000000/880000/874400/874388/9148c40a_y.jpg) ### Courtyard by Marriott Louisville Airport 10/10 Excellent "Very nice staff and big clean rooms " [](https://expedia.ca/Louisville-Hotels-Courtyard-By-Marriott-Louisville-Airport.h874388.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Duncan](https://www.expedia.ca/5Star-Duncan-Georgetown-Hotels.s50-n553248635975849362-0.Travel-Guide-Filter-Hotels) - [Hotels near Atlantis Waterpark](https://www.expedia.ca/Atlantis-Waterpark-Hotels.0-l553248621532656248-0.Travel-Guide-Filter-Hotels) - 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