Title: Isla Grande Vacation Home Rentals from CA $146: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Isla Grande](https://expedia.ca/Isla-Grande-Hotels.d6053183.Travel-Guide-Hotels)[Vacation Rentals in Isla Grande](https://expedia.ca/Isla-Grande-Vacation-Rentals.d6053183.Travel-Guide-VacationRentals)[Flights to Isla Grande](https://expedia.ca/Cheap-Flights-To-Isla-Grande.d6053183.Travel-Guide-Flights)[Isla Grande Car Rentals](https://expedia.ca/Car-Rentals-In-Isla-Grande.d6053183.Car-Rental-Guide)[Isla Grande Vacation Packages](https://expedia.ca/Isla-Grande.d6053183.Destination-Travel-Guides) ![Palm trees forest and houses in Isla Grande shore. Colon province, Panama, Caribbean, Central America.](https://images.trvl-media.com/place/6053183/8bba6d27-3102-43e6-89e4-9ef59409f2b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6053183/8bba6d27-3102-43e6-89e4-9ef59409f2b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 15 - May 17](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jun 12 - Jun 14](https://www.expedia.ca/Hotel-Search?regionId=6053183&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isla Grande vacation homes ![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/30f0b989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/66a17c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/551ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deluxe Beachfront 4-bedroom house in Colón Province [](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) Colón Province CA $462 CA $526 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/1e44d7b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/9f704818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/fef7062f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Despierta sobre el mar [](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) Garrote 6.0/10 (1 review) CA $102 CA $146 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/1649bd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/073e10ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/4fd01df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/7ad3ced9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabaña La Punta op het Strand!! [](https://www.expedia.ca/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information) Colón Province CA $177 CA $231 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-02&endDate=2026-03-03®ionId=6053183&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_6053183) ## Find vacation rentals that suit your style Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Isla+Grande%2C+Col%C3%B3n%2C+Panama®ionId=6053183&latLong=9.634628%2C-79.562556&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=VACATION_HOME) Villas [](https://www.expedia.ca/Hotel-Search?destination=Isla+Grande%2C+Col%C3%B3n%2C+Panama®ionId=6053183&latLong=9.634628%2C-79.562556&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=VILLA) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Isla+Grande%2C+Col%C3%B3n%2C+Panama®ionId=6053183&latLong=9.634628%2C-79.562556&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=APARTMENT) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Isla+Grande%2C+Col%C3%B3n%2C+Panama®ionId=6053183&latLong=9.634628%2C-79.562556&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=COTTAGE) Condos [](https://www.expedia.ca/Hotel-Search?destination=Isla+Grande%2C+Col%C3%B3n%2C+Panama®ionId=6053183&latLong=9.634628%2C-79.562556&adults=2&startDate=2026-05-17&d1=2026-05-17&endDate=2026-05-20&d2=2026-05-20&lodging=CONDO) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FIsla-Grande-Private-Vacation-Homes.d6053183-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FIsla-Grande-Private-Vacation-Homes.d6053183-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Isla Grande Hotel Reviews ![Casa Congo - Rayo Verde - Restaurante](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/8f40c1a0_y.jpg) ### Casa Congo - Rayo Verde - Restaurante 10/10 Excellent "Spotless gorgeous room with views! Delicious restaurant. It was stormy so we didn't get to see the beach but we loved our stay anyway!" [](https://expedia.ca/Portobelo-Hotels-Casa-Congo-Rayo-Verde-Restaurante.h15362713.Hotel-Information) ![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3_y.jpg) ### Ciel y Miel 10/10 Excellent "The views from this mountain-top boutique hotel are extraordinary." [](https://expedia.ca/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) ![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041_y.jpg) ### Ordovician Beach Resort 10/10 Excellent "The best service in Panama!!! We truly felt cared for in every detail — the team is attentive, warm, and genuinely professional. The food was outstanding: the chef is exceptional! Every dish reflected passion, quality, and pride. This hotel is located on a beautiful Caribbean island, surrounded by untouched nature, turquoise waters, and a truly magical atmosphere. What made it even more special was the silence and privacy — only the sound of the waves and the singing of birds!) A wonderful resort and a place we’ll definitely return to!" [](https://expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information) ![Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/cf8e1124_y.jpg) ### Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita 10/10 Excellent "Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!" [](https://expedia.ca/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information) ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg) ### Hotel Cocotal 10/10 Excellent "Excelente hospedaje lo mejor la amabilidad de José Ángel y los demás muchachos... Con decirles que hasta te llevan a la habitación si te has tomado algunos tragos.. recomendada al 100" [](https://expedia.ca/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information) ![La Posada del Buzo](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/984fa3bd_y.jpg) ### La Posada del Buzo 10/10 Excellent "Great spot for scuba diving, amazing staff, family owned and operated dive facility and hotel. Restaurant on site with delicious food." [](https://expedia.ca/Portobelo-Hotels-Hotel-Panama-Dive-Adventure.h90295300.Hotel-Information) ![BEAUTIFUL APARTMENT IN FRONT OF THE SEA](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/w1064h805x0y11-7ae51d02_y.jpg) ### BEAUTIFUL APARTMENT IN FRONT OF THE SEA 10/10 Excellent "All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!" [](https://expedia.ca/Portobelo-Hotels-BEAUTIFUL-APARTMENT-IN-FRONT-OF-THE-SEA.h74054867.Hotel-Information) ![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0_y.jpg) ### Ranchos de Chalia 10/10 Excellent "Beautiful tranquility in nature, amazing staff" [](https://expedia.ca/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) ![Piscina Mar en el Paraíso Caribe](https://images.trvl-media.com/lodging/100000000/99550000/99543300/99543203/87160e38_y.jpg) ### Piscina Mar en el Paraíso Caribe 6/10 Okay "Staff, especially William, was helpful. The elevator did not work for a couple of days and 8th floor was a bit of a walk. The driveway access is in a really poor condition. The room was just fine. " [](https://expedia.ca/Maria-Chiquita-Hotels-Piscina-Mar-En-El-Paraiso-Caribe.h99543203.Hotel-Information) ## Find out more about Isla Grande ## Isla Grande Vacation Homes information | Number of reviews | 1 | | ----------------- | ----------------- | | Accommodation | 19 Vacation Homes | | Lowest Price | CA $146 | | Highest Price | CA $526 |