Title: Book the Best Isernia LUXURY Hotels - Upscale Hotels in Isernia | Expedia.ca [Hotels in Isernia](https://expedia.ca/Isernia-Hotels.d6123603.Travel-Guide-Hotels)[Vacation Rentals in Isernia](https://expedia.ca/Isernia-Vacation-Rentals.d6123603.Travel-Guide-VacationRentals)[Flights to Isernia](https://expedia.ca/Cheap-Flights-To-Isernia.d6123603.Travel-Guide-Flights)[Things to do in Isernia](https://expedia.ca/Things-To-Do-In-Isernia.d6123603.Travel-Guide-Activities)[Isernia Car Rentals](https://expedia.ca/Car-Rentals-In-Isernia.d6123603.Car-Rental-Guide)[Isernia Vacation Packages](https://expedia.ca/Isernia.d6123603.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Isernia - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Isernia Luxury Hotels Tonight [Nov 10 - Nov 11](https://www.expedia.ca/Hotel-Search?regionId=6123603&startDate=2025-11-10&endDate=2025-11-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 11 - Nov 12](https://www.expedia.ca/Hotel-Search?regionId=6123603&startDate=2025-11-11&endDate=2025-11-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6123603&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6123603&startDate=2025-11-21&endDate=2025-11-23&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Isernia Luxury Hotels ## Top Isernia Hotel Reviews ![Fonte del Benessere Resort](//images.trvl-media.com/lodging/5000000/4340000/4339000/4338927/862fbb8d_y.jpg) ### Fonte del Benessere Resort 10/10 Excellent "Amazing stay. Friendly helpful staff. Food was good. Bed was comfortable. Very clean. " [](https://expedia.ca/Castelpetroso-Hotels-Fonte-Del-Benessere-Resort.h4338927.Hotel-Information) ## Frequently asked questions ### Which area of Isernia is best to stay in for luxury hotels? > The best area to stay in Isernia for luxury hotels is the historic centre, particularly around Corso Marcelli and Piazza Celestino V. > > > > This central area is the heart of Isernia, featuring many of the city's important historical buildings and amenities. Corso Marcelli is the main street, lined with shops, cafes, and restaurants, and runs through the core of the old town. Piazza Celestino V, with its iconic Fontana Fraterna, is a key landmark and a pleasant spot to relax. The layout is quite walkable, allowing easy exploration of the ancient Roman and Samnite ruins. > > > > Couples looking for a refined experience will find the historic centre appealing. It offers a blend of cultural exploration with convenient access to high-quality dining and sophisticated accommodation options. You'll be able to enjoy leisurely strolls through cobbled streets and discover local craft shops. > > > > For travellers who appreciate convenience and a touch of elegance, hotels within this central zone often provide a higher standard of service and amenities. ### How much does a luxury hotel in Isernia cost? > Luxury hotel prices in Isernia vary, but you can find a great deal on Expedia. To find the best prices on luxury stays, be flexible with your dates—typically, off-peak and mid-week stays are cheaper. Sort your search results by "Price: low to high" to see our lowest rates. ### What luxury activities and experiences are there in Isernia? > For luxury travellers seeking great experiences in Isernia, the best options often involve exploring the region's rich history, culinary traditions, and natural beauty with an emphasis on exclusivity and comfort. > > > > Molise offers bespoke archaeological tours. You could arrange a private guided visit to the Palaeolithic site of La Pineta, one of Europe's most significant prehistoric discoveries, or explore the Roman ruins of Aesernia. These tours can be tailored to your interests, offering in-depth insights without the crowds. > > > > For those who appreciate fine food and drink, Isernia and its surroundings provide excellent opportunities for private culinary experiences. This could include a truffle hunting excursion with a local expert and their trained dogs, followed by a private cooking class focusing on regional Molise dishes, often held in a historic villa or a family-run agriturismo. You might also enjoy exclusive wine tastings at local vineyards that produce the region's distinctive Tintilia wine. > > > > Nature lovers can enjoy personalised excursions into the Matese Regional Park or the Abruzzo, Lazio and Molise National Park. This could involve guided hikes with a private naturalist, perhaps focusing on birdwatching or identifying local flora, or even a horseback riding tour through the picturesque Molise countryside, arranged with a focus on comfort and scenic routes. > > > > For a relaxing and indulgent experience, consider booking a stay at one of Molise's charming boutique hotels or restored country estates. ### How can I save on a luxury hotel in Isernia with Expedia? > There are plenty of ways to save on a luxury hotel in Isernia. Unlock our lowest prices by joining [One Key™](https://www.expedia.ca/welcome-one-key), Expedia's travel rewards program. It's free and easy to sign up, and you can access member perks too. Typically, booking in advance will help you save on your luxury hotel booking. If you're feeling spontaneous, be sure to check for last-minute deals. ### Is it cheaper to book a luxury Isernia hotel and flights as a package? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package. ### Can I cancel my luxury hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. 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