Title: Book the Best Irvine Research Center Hotels with smoking rooms in 2025 | Expedia.ca [Vacation Rentals in Irvine](https://expedia.ca/Irvine-Vacation-Rentals.d7819.Travel-Guide-VacationRentals)[Flights to Irvine](https://expedia.ca/Cheap-Flights-To-Irvine.d7819.Travel-Guide-Flights)[Things to do in Irvine](https://expedia.ca/Things-To-Do-In-Irvine.d7819.Travel-Guide-Activities)[Irvine Research Center Car Rentals](https://expedia.ca/Car-Rentals-In-Irvine-Research-Center.d553248635976470092.Car-Rental-Guide)[Irvine Research Center Vacations](https://expedia.ca/Irvine-Research-Center.d553248635976470092.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Smoking Hotels in Irvine Research Center, Irvine ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Irvine Research Center Hotels with smoking rooms Tonight [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=553248635976470092&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976470092&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976470092&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976470092&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Irvine Research Center Hotels with smoking rooms ## Top Irvine Research Center Hotel Reviews ![Hotel Lulu, BW Premier Collection](//images.trvl-media.com/lodging/1000000/30000/21000/20965/cc6bb6ca_y.jpg) ### Hotel Lulu, BW Premier Collection 10/10 Excellent "Really convenient location. The staff was super friendly and accommodating. I liked the decorations and welcome cocktail. I was disappointed that there was nowhere to fill my reusable water bottle though. " [](https://expedia.ca/Anaheim-Hotels-Hotel-Lulu.h20965.Hotel-Information) ![Anaheim Majestic Garden Hotel](//images.trvl-media.com/lodging/1000000/30000/24200/24131/b67790ff_y.jpg) ### Anaheim Majestic Garden Hotel 10/10 Excellent "The shuttle to Disneyland is reliable and easy, and they take pains to accommodate rush times. I have never had any problem getting back and forth when I needed to. It's worth staying there just for that. My suggestion for improvement is that the rooms could use some USB charging ports, and the room's desk area wasn't near a convenient outlet for the computer - a bit of rearranging would make this better." [](https://expedia.ca/Anaheim-Hotels-Anaheim-Majestic-Garden-Hotel.h24131.Hotel-Information) ![Motel 6 Anaheim Maingate](//images.trvl-media.com/lodging/1000000/690000/688800/688752/c5c0b118_y.jpg) ### Motel 6 Anaheim Maingate 10/10 Excellent "Great location to Disney, Ubers were less than $8 and very close to the park..great price and will stay here again " [](https://expedia.ca/Anaheim-Hotels-Motel-6-Anaheim-Maingate.h688752.Hotel-Information) ![Hyatt Regency Orange County](//images.trvl-media.com/lodging/1000000/20000/16000/15965/22d7d677_y.jpg) ### Hyatt Regency Orange County 10/10 Excellent "Great hotel with everything you need!" 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