Title: Book the Best BUSINESS Hotels in Independence in 2026 | Expedia.ca [Hotels in Independence](https://expedia.ca/Independence-Hotels.d118113.Travel-Guide-Hotels)[Vacation Rentals in Independence](https://expedia.ca/Independence-Vacation-Rentals.d118113.Travel-Guide-VacationRentals)[Independence Car Rentals](https://expedia.ca/Car-Rentals-In-Independence.d118113.Car-Rental-Guide)[Independence Vacation Packages](https://expedia.ca/Independence.d118113.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Independence, IA from CA $99 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Independence Business Hotels Tonight [Dec 5 - Dec 6](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2025-12-05&endDate=2025-12-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 6 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2025-12-06&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Independence Business Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/25195839.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/4ac6c082.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/39c2f576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/4ea7881b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Independence IA Independence 8.6/10 Excellent (176) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $107 CA $120 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Waterloo-Hotels-Super-8-By-Wyndham-Independence.h855446.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/d2a1ed9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/6815e07c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/fddcab92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/aeec7064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Independence Independence 8.8/10 Excellent (361) "The hotel was clean, comfortable, and our room had a beautiful view of the sunset. The part that stood out was the friendly staff and amazing customer service. We were there Thanksgiving & asked about hours of establishments. Staff called and verified hours for us, found options for food and entertainment! Small town with big love! Thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacey CA $158 CA $176 total includes taxes & fees Dec 13 - Dec 14 [](https://www.expedia.ca/Waterloo-Hotels-Comfort-Inn-Suites-Independence.h1492519.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/a44c8c8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/d09fd932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/b6224ca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/11179eb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites – Manchester Manchester 9.0/10 Wonderful (323) "The room was very clean, and the reception staff were very friendly." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) María Isabel CA $129 CA $146 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Dubuque-Hotels-Cobblestone-Inn-Suites-Manchester.h32942250.Hotel-Information) ![42-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/bdf477b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/b2021f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/d39fe3c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/2084896e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cornerstone Inn & Suites Oelwein 9.2/10 Wonderful (471) "Always a nice quit stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sue CA $111 CA $124 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Waterloo-Hotels-Cornerstone-Inn-Suites.h21427076.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/6896fad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/804070f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/4185cdff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/0129133f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Evansdale Waterloo Evansdale 8.4/10 Very good (502) "The room was very clean and common areas well maintained. Great breakfast options." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sophia CA $88 CA $99 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Waterloo-Hotels-Days-Inn-By-Wyndham-Evansdale-Waterloo.h14356.Hotel-Information) ![Premier Suite, 1 King Bed, Non Smoking (Second Floor)](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/b3fc3bf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking | Accessible bathroom](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/fcc8563b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/927049a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/aca3bc59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Oelwein Oelwein 7.8/10 Good (160) "friendly people " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $95 CA $106 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Waterloo-Hotels-Super-8-By-Wyndham-Oelwein.h31961561.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/d3c02cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/15a0d492.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/ab1dd016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible Roll in Shower, Non Smoking](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/95326be2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites - Vinton Vinton 8.6/10 Excellent (296) "You can tell it's an older building but It was clean and comfortable with all the basics for travel needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $125 CA $141 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Vinton-Hotels-Cobblestone-Inn-Suites-Vinton.h3551434.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/3b2ada0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/23cddf4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/91448438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/009477bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isle Casino Hotel - Waterloo - A Caesars Rewards Destination Waterloo 8.2/10 Very good (1001) "Staff was very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie [](https://www.expedia.ca/Waterloo-Hotels-Isle-Casino-Hotel-Waterloo.h1829121.Hotel-Information) ![Suite, One King Bed, Non-Smoking](https://images.trvl-media.com/lodging/2000000/1520000/1518600/1518540/602c23e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1520000/1518600/1518540/7bd3adbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1518600/1518540/06105b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1520000/1518600/1518540/0824d4d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Waterloo Cedar Valley Waterloo 8.8/10 Excellent (907) "Clean nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alicia CA $112 CA $126 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Waterloo-Hotels-Hampton-Inn-Waterloo.h1518540.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/6f8ec2f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/11716169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/21bf97ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/adf1acec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Waterloo, IA Waterloo 7.6/10 Good (1001) "Breakfast was good and facilities were clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Greg CA $98 CA $115 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Waterloo-Hotels-Country-Inn-Suites-By-Radisson.h119221.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-20&endDate=2025-12-21®ionId=118113&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Independence Hotel Reviews ![Days Inn by Wyndham Evansdale Waterloo](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/6896fad7_y.jpg) ### Days Inn by Wyndham Evansdale Waterloo 10/10 Excellent "The room was clean and the staff pleasant!" [](https://expedia.ca/Waterloo-Hotels-Days-Inn-By-Wyndham-Evansdale-Waterloo.h14356.Hotel-Information) ![Comfort Inn & Suites Independence](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/d2a1ed9e_y.jpg) ### Comfort Inn & Suites Independence 10/10 Excellent "The hotel was clean, comfortable, and our room had a beautiful view of the sunset. The part that stood out was the friendly staff and amazing customer service. We were there Thanksgiving & asked about hours of establishments. Staff called and verified hours for us, found options for food and entertainment! Small town with big love! Thank you!" [](https://expedia.ca/Waterloo-Hotels-Comfort-Inn-Suites-Independence.h1492519.Hotel-Information) ![Days Inn & Suites by Wyndham Waterloo](https://images.trvl-media.com/lodging/1000000/40000/36600/36538/8d23362f_y.jpg) ### Days Inn & Suites by Wyndham Waterloo 10/10 Excellent "The room was very clean the customer service was the best Because he was there he was there breakfast was nice The workers were real good I will stay there again And the owner was very nice he let us Come early and track in And I appreciate the whole staff ." [](https://expedia.ca/Waterloo-Hotels-Days-Inn-Suites-By-Wyndham-Waterloo.h36538.Hotel-Information) ![Isle Casino Hotel - Waterloo - A Caesars Rewards Destination](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/3b2ada0e_y.jpg) ### Isle Casino Hotel - Waterloo - A Caesars Rewards Destination 10/10 Excellent "Room clean, staff great. Food good. " [](https://expedia.ca/Waterloo-Hotels-Isle-Casino-Hotel-Waterloo.h1829121.Hotel-Information) ![Urbana Inn & Suites](https://images.trvl-media.com/lodging/1000000/900000/898000/897975/a2447aec_y.jpg) ### Urbana Inn & Suites 10/10 Excellent "The room was very clean and staff was very friendly. Loved that they had a continental breakfast…waffle maker, cold cereal, fresh fruit, breakfast bars and such. It is an older hotel but very clean and was the shower/tub was very, very clean. I also appreciate the two bed room option. Loved that it is a few minutes from family that we come to visit during the Thanksgiving Holiday. Will be back again next year." [](https://expedia.ca/Urbana-Hotels-Urbana-Inn-Suites.h897975.Hotel-Information) ![Country Inn & Suites by Radisson, Waterloo, IA](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/6f8ec2f3_y.jpg) ### Country Inn & Suites by Radisson, Waterloo, IA 10/10 Excellent "Very clean room and the breakfast was very hearty!!! Very friendly staff." [](https://expedia.ca/Waterloo-Hotels-Country-Inn-Suites-By-Radisson.h119221.Hotel-Information) ![Baymont by Wyndham Waterloo](https://images.trvl-media.com/lodging/1000000/20000/17900/17890/ef27b857_y.jpg) ### Baymont by Wyndham Waterloo 10/10 Excellent "Yes very clean and please " [](https://expedia.ca/Waterloo-Hotels-Baymont-By-Wyndham-Waterloo.h17890.Hotel-Information) ![Best Western Plus Waterloo & Cedar Falls](https://images.trvl-media.com/lodging/1000000/30000/26100/26079/f41bae14_y.jpg) ### Best Western Plus Waterloo & Cedar Falls 10/10 Excellent "Yes" [](https://expedia.ca/Waterloo-Hotels-Best-Western-Plus-Executive-Residency-Waterloo-Cedar-Falls.h26079.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Independence cost? ### Why book your business-friendly hotel in Independence with Expedia? ### How can I find cheap business-friendly hotels in Independence? ### What is there to do in Independence near my business-friendly hotel? ## Explore a world of travel with Expedia - 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