Title: Book the Best BUSINESS Hotels in Independence in 2026 | Expedia.ca [Hotels in Independence](https://expedia.ca/Independence-Hotels.d118113.Travel-Guide-Hotels)[Vacation Rentals in Independence](https://expedia.ca/Independence-Vacation-Rentals.d118113.Travel-Guide-VacationRentals)[Independence Car Rentals](https://expedia.ca/Car-Rentals-In-Independence.d118113.Car-Rental-Guide)[Independence Vacation Packages](https://expedia.ca/Independence.d118113.Destination-Travel-Guides) ![Independence, Missouri, USA - June 16, 2023: Afternoon sunlight shines on the historic core of downtown Independence.](https://images.trvl-media.com/place/118113/2ed5d977-f638-4911-8392-3d6465bbc21b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/118113/2ed5d977-f638-4911-8392-3d6465bbc21b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Independence Business Hotels Tonight [Mar 16 - Mar 17](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2026-03-16&endDate=2026-03-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Mar 17 - Mar 18](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2026-03-17&endDate=2026-03-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=118113&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Independence business-friendly hotels ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/d3ac5bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/39c2f576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/ce196cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/860000/855500/855446/4ac6c082.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Independence IA [](https://www.expedia.ca/Waterloo-Hotels-Super-8-By-Wyndham-Independence.h855446.Hotel-Information) Independence 8.6/10 Excellent (178 reviews) "Nice and quiet, comfortable bed, staff is friendly, nice stay overnight " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $123 CA $138 total includes taxes & fees Mar 20 - Mar 21 [](https://www.expedia.ca/Waterloo-Hotels-Super-8-By-Wyndham-Independence.h855446.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/d2a1ed9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/fddcab92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/6815e07c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/a6552b5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Independence [](https://www.expedia.ca/Waterloo-Hotels-Comfort-Inn-Suites-Independence.h1492519.Hotel-Information) Independence 8.8/10 Excellent (374 reviews) "Clean hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $169 CA $189 total includes taxes & fees Apr 3 - Apr 4 [](https://www.expedia.ca/Waterloo-Hotels-Comfort-Inn-Suites-Independence.h1492519.Hotel-Information) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/221ca605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/d09fd932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/81ac9570.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/33000000/32950000/32942300/32942250/0792afb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites – Manchester [](https://www.expedia.ca/Dubuque-Hotels-Cobblestone-Inn-Suites-Manchester.h32942250.Hotel-Information) Manchester 9.0/10 Wonderful (343 reviews) "A very nice and clean room, and very pleasant staff member checked us in, i would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $151 CA $171 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Dubuque-Hotels-Cobblestone-Inn-Suites-Manchester.h32942250.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/a512e4f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/5ce22208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/938f65b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/a03991be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Waterloo, IA [](https://www.expedia.ca/Waterloo-Hotels-Country-Inn-Suites-By-Radisson.h119221.Hotel-Information) Waterloo 10/10 Exceptional (5 reviews) "Staff was so helpful and friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooke CA $115 CA $129 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Waterloo-Hotels-Country-Inn-Suites-By-Radisson.h119221.Hotel-Information) ![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/c441b2d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/b1c40033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/f743e1a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/2a490771.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Evansdale Waterloo [](https://www.expedia.ca/Waterloo-Hotels-Days-Inn-By-Wyndham-Evansdale-Waterloo.h14356.Hotel-Information) Evansdale 8.4/10 Very good (523 reviews) "Yes it was very cozy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dillon CA $92 CA $103 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Waterloo-Hotels-Days-Inn-By-Wyndham-Evansdale-Waterloo.h14356.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/2084896e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/bdf477b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Jetted Tub](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/0bd6a856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite](https://images.trvl-media.com/lodging/22000000/21430000/21427100/21427076/52a5adcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cornerstone Inn & Suites [](https://www.expedia.ca/Waterloo-Hotels-Cornerstone-Inn-Suites.h21427076.Hotel-Information) Oelwein 9.2/10 Wonderful (488 reviews) "Great staff and amenities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky CA $116 CA $130 total includes taxes & fees Mar 27 - Mar 28 [](https://www.expedia.ca/Waterloo-Hotels-Cornerstone-Inn-Suites.h21427076.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/23cddf4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/491b9324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/bccf097b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Non-Smoking](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/9a548dd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isle Casino Hotel - Waterloo - A Caesars Rewards Destination [](https://www.expedia.ca/Waterloo-Hotels-Isle-Casino-Hotel-Waterloo.h1829121.Hotel-Information) Waterloo 8.2/10 Very good (1,002 reviews) "Clean rooms, comfortable beds,great pool area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shona CA $99 CA $129 total includes taxes & fees Mar 18 - Mar 19 [](https://www.expedia.ca/Waterloo-Hotels-Isle-Casino-Hotel-Waterloo.h1829121.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/2f062a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/d3c02cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/8afbbe60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible Roll in Shower, Non Smoking](https://images.trvl-media.com/lodging/4000000/3560000/3551500/3551434/646ab6da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites - Vinton [](https://www.expedia.ca/Vinton-Hotels-Cobblestone-Inn-Suites-Vinton.h3551434.Hotel-Information) Vinton 8.6/10 Excellent (304 reviews) "Rooms were clean. Beds comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pam CA $127 CA $142 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Vinton-Hotels-Cobblestone-Inn-Suites-Vinton.h3551434.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/121000000/120340000/120332900/120332870/78573df5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/121000000/120340000/120332900/120332870/w3840h2557x0y3-870f2b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking, Kitchen (Full Kitchen)](https://images.trvl-media.com/lodging/121000000/120340000/120332900/120332870/5b22ad52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120340000/120332900/120332870/w3837h2556x3y4-ae6c622f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Executive Residency By Best Western Waterloo & Cedar Falls [](https://www.expedia.ca/Waterloo-Hotels-Executive-Residency-By-Best-Western-Waterloo-Cedar-Falls.h120332870.Hotel-Information) Waterloo 9.4/10 Exceptional (9 reviews) "Clan room, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Courtney CA $125 CA $141 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Waterloo-Hotels-Executive-Residency-By-Best-Western-Waterloo-Cedar-Falls.h120332870.Hotel-Information) ![Premier Suite, 1 King Bed, Non Smoking (Second Floor)](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/6309b8c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/b3ae0d78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/05194180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31970000/31961600/31961561/5b041978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Oelwein [](https://www.expedia.ca/Waterloo-Hotels-Super-8-By-Wyndham-Oelwein.h31961561.Hotel-Information) Oelwein 7.8/10 Good (163 reviews) "The people here are amazing. Cannot get a better hotel for the price!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin CA $110 CA $123 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Waterloo-Hotels-Super-8-By-Wyndham-Oelwein.h31961561.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-31&endDate=2026-04-01®ionId=118113&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Independence Hotel Reviews ![Country Inn & Suites by Radisson, Waterloo, IA](https://images.trvl-media.com/lodging/1000000/120000/119300/119221/a512e4f2_y.jpg) ### Country Inn & Suites by Radisson, Waterloo, IA 10/10 Excellent "Room was very clean and quiet, check in was easy and quick." [](https://expedia.ca/Waterloo-Hotels-Country-Inn-Suites-By-Radisson.h119221.Hotel-Information) ![Comfort Inn & Suites Independence](https://images.trvl-media.com/lodging/2000000/1500000/1492600/1492519/d2a1ed9e_y.jpg) ### Comfort Inn & Suites Independence 10/10 Excellent "I also stay at this location when we visit our family friend who lives in Independence. This was extra special because there was a surprise blue grass jam!!" [](https://expedia.ca/Waterloo-Hotels-Comfort-Inn-Suites-Independence.h1492519.Hotel-Information) ![Isle Casino Hotel - Waterloo - A Caesars Rewards Destination](https://images.trvl-media.com/lodging/2000000/1830000/1829200/1829121/23cddf4e_y.jpg) ### Isle Casino Hotel - Waterloo - A Caesars Rewards Destination 10/10 Excellent "Great place reasonably priced hot tub and pool w arcade definitely ok to have kids here " [](https://expedia.ca/Waterloo-Hotels-Isle-Casino-Hotel-Waterloo.h1829121.Hotel-Information) ![Baymont by Wyndham Waterloo](https://images.trvl-media.com/lodging/1000000/20000/17900/17890/caec61c6_y.jpg) ### Baymont by Wyndham Waterloo 8/10 Good "Everything was clean and convenient. I had a special request and staff happily helped me. I will be staying there again when i return this summer." [](https://expedia.ca/Waterloo-Hotels-Baymont-By-Wyndham-Waterloo.h17890.Hotel-Information) ![Days Inn by Wyndham Evansdale Waterloo](https://images.trvl-media.com/lodging/1000000/20000/14400/14356/c441b2d7_y.jpg) ### Days Inn by Wyndham Evansdale Waterloo 10/10 Excellent "Yes it was very cozy" [](https://expedia.ca/Waterloo-Hotels-Days-Inn-By-Wyndham-Evansdale-Waterloo.h14356.Hotel-Information) ![Days Inn & Suites by Wyndham Waterloo](https://images.trvl-media.com/lodging/1000000/40000/36600/36538/8d23362f_y.jpg) ### Days Inn & Suites by Wyndham Waterloo 10/10 Excellent "Beds were quite comfortable and an excellent price point" [](https://expedia.ca/Waterloo-Hotels-Days-Inn-Suites-By-Wyndham-Waterloo.h36538.Hotel-Information) ![Best Western Plus Waterloo & Cedar Falls](https://images.trvl-media.com/lodging/1000000/30000/26100/26079/f41bae14_y.jpg) ### Best Western Plus Waterloo & Cedar Falls 10/10 Excellent "There was no hot tub and i thought there was suppose to be one. I normally only book hotels with hot tubs so i can relax in it in the evening. " [](https://expedia.ca/Waterloo-Hotels-Best-Western-Plus-Executive-Residency-Waterloo-Cedar-Falls.h26079.Hotel-Information) ![Fairfield Inn & Suites by Marriott Waterloo Cedar Falls](https://images.trvl-media.com/lodging/10000000/9070000/9069900/9069857/70f93569_y.jpg) ### Fairfield Inn & Suites by Marriott Waterloo Cedar Falls 6/10 Okay "Yes" [](https://expedia.ca/Waterloo-Hotels-Fairfield-Inn-Suites-By-Marriott-Waterloo-Cedar-Falls.h9069857.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Independence cost? ### Why book your business-friendly hotel in Independence with Expedia? ### How can I find cheap business-friendly hotels in Independence? ### What is there to do in Independence near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in Manchester ](https://www.expedia.ca/4Star-Manchester-Hotels.s40-0-d602020.Travel-Guide-Filter-Hotels) - 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