Title: Illinois Medical District Station Vacation Home Rentals : Search Top Private Vacation Homes for Rent | Expedia.ca

[Near West Side Travel Guide](https://expedia.ca/Chicago-Near-West-Side.dx6132434)[Illinois Medical District Station Hotels](https://expedia.ca/Illinois-Medical-District-Station-Hotels.d6210751.Travel-Guide-Hotels)[Near West Side Car Rentals](https://expedia.ca/Car-Rentals-In-Near-West-Side.d6132434.Car-Rental-Guide)[Near West Side Vacation Packages](https://expedia.ca/Near-West-Side.d6132434.Destination-Travel-Guides)

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## Check prices for these dates

In two weeks

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6210751&startDate=2026-02-13&endDate=2026-02-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6210751&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Apr 24 - Apr 26](https://www.expedia.ca/Hotel-Search?regionId=6210751&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=6210751&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Illinois Medical District Station vacation homes

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/122000000/121880000/121874600/121874507/b7c99ded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/122000000/121880000/121874600/121874507/fdfb3c82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/122000000/121880000/121874600/121874507/ca524ef1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/122000000/121880000/121874600/121874507/42930976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### WINTER DISCOUNTED! Relax with family in a super Lux Custom SFH. West town.

[](https://www.expedia.ca/Chicago-Hotels-Relax-With-Family-In-A-Super-Lux-5-Bedroom-House-W-Movie-Theater-And-Full-Gym.h121874507.Hotel-Information)

West Town

10/10

Exceptional

(2 reviews)

"Erik was a wonderful host. Super responsive, and the home was immaculate and well-supplied. thank you so much!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rose G.

[](https://www.expedia.ca/Chicago-Hotels-Relax-With-Family-In-A-Super-Lux-5-Bedroom-House-W-Movie-Theater-And-Full-Gym.h121874507.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/27000000/26570000/26561800/26561748/c266ceb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/27000000/26570000/26561800/26561748/cf94a216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/27000000/26570000/26561800/26561748/38a018f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/27000000/26570000/26561800/26561748/f8a98a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful Modern Designer Home \~ Downtown - 4-Bed/4-Bath

[](https://www.expedia.ca/Chicago-Hotels-Beautiful-Modern-Designer-Home-Downtown-4-Bed4-Bath.h26561748.Hotel-Information)

West Town

10/10

Exceptional

(94 reviews)

"Perfect for a girls trip!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica B.

[](https://www.expedia.ca/Chicago-Hotels-Beautiful-Modern-Designer-Home-Downtown-4-Bed4-Bath.h26561748.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/75000000/74520000/74514700/74514663/w1828h1214x0y0-d651ee24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/75000000/74520000/74514700/74514663/0281e3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/75000000/74520000/74514700/74514663/0f9ca56e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/75000000/74520000/74514700/74514663/w954h1469x0y0-e35cd045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### EAST VILLAGE 4-LEVEL-HOUSE WITH 5 BATHS & COVERED ATTACHED GARAGE

[](https://www.expedia.ca/Chicago-Hotels-EAST-VILLAGE-4-LEVEL-HOUSE-WITH-5-BATHS-COVERED-ATTACHED-GARAGE.h74514663.Hotel-Information)

West Town

9.0/10

Wonderful

(24 reviews)

"The property was great and accommodated 11 people nicely "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marni S.

[](https://www.expedia.ca/Chicago-Hotels-EAST-VILLAGE-4-LEVEL-HOUSE-WITH-5-BATHS-COVERED-ATTACHED-GARAGE.h74514663.Hotel-Information)

![Smart TV, stereo, printers](https://images.trvl-media.com/lodging/55000000/54240000/54234400/54234310/4ad9c742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/55000000/54240000/54234400/54234310/6ac2cdae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, stereo, printers](https://images.trvl-media.com/lodging/55000000/54240000/54234400/54234310/f2547b8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/55000000/54240000/54234400/54234310/6a471249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury Modern home minutes from Downtown Chicago

[](https://www.expedia.ca/Chicago-Hotels-Luxury-Modern-Home-Minutes-From-Downtown-Chicago.h54234310.Hotel-Information)

Lower West Side

10/10

Exceptional

(19 reviews)

"Great visit and accommodations. Pilson is a great place that is close enough to downtown!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ryan S.

[](https://www.expedia.ca/Chicago-Hotels-Luxury-Modern-Home-Minutes-From-Downtown-Chicago.h54234310.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/96000000/95510000/95508100/95508001/13fbfe4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/95510000/95508100/95508001/24c3e774.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/95510000/95508100/95508001/dd5a1e07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/96000000/95510000/95508100/95508001/160a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Newly Updated Vintage 6 Bedroom Single Family Home by AllSet Turnover

[](https://www.expedia.ca/Chicago-Hotels-Newly-Updated-Vintage-6-Bedroom-Single-Family-Home-By-AllSet-Turnover.h95508001.Hotel-Information)

Near West Side

9.0/10

Wonderful

(19 reviews)

"Great location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Terran A.

[](https://www.expedia.ca/Chicago-Hotels-Newly-Updated-Vintage-6-Bedroom-Single-Family-Home-By-AllSet-Turnover.h95508001.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68760000/68751700/68751679/2d76c5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68760000/68751700/68751679/w905h683x60y0-ffba150b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68760000/68751700/68751679/w904h683x60y0-7856b4cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/69000000/68760000/68751700/68751679/w571h683x227y0-1ba1e1a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HUGE 1700 sqft 3bd West Loop Penthouse w/ Balcony

[](https://www.expedia.ca/Chicago-Hotels-HUGE-1700-Sqft-3bd-West-Loop-Penthouse-W-Balcony.h68751679.Hotel-Information)

Downtown Chicago

9.4/10

Exceptional

(62 reviews)

"Fantastic location in the West Loop with a magnificent view of Willis Tower. The place was spacious for a family of five."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Clare N.

[](https://www.expedia.ca/Chicago-Hotels-HUGE-1700-Sqft-3bd-West-Loop-Penthouse-W-Balcony.h68751679.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76450000/76449200/76449115/w3263h2176x1y1-21d195ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/77000000/76450000/76449200/76449115/w3263h2177x1y1-b0b55884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, foosball, stereo](https://images.trvl-media.com/lodging/77000000/76450000/76449200/76449115/w3263h2177x1y1-3cd8ba9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, foosball, stereo](https://images.trvl-media.com/lodging/77000000/76450000/76449200/76449115/w3263h2176x1y1-c8b308fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stunning MODERN Home Downtown/RiverWest Close to Fulton Market & United Center

[](https://www.expedia.ca/Chicago-Hotels-Stunning-MODERN-Home-DowntownRiverWest-Close-To-Fulton-Market-United-Center.h76449115.Hotel-Information)

West Town

9.8/10

Exceptional

(23 reviews)

"Great space. Great location. Walkable to restaurants, bars and shops. Nice bed linens. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Donna C.

[](https://www.expedia.ca/Chicago-Hotels-Stunning-MODERN-Home-DowntownRiverWest-Close-To-Fulton-Market-United-Center.h76449115.Hotel-Information)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/86000000/85480000/85480000/85479906/4c154a19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/86000000/85480000/85480000/85479906/524db80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/86000000/85480000/85480000/85479906/f6757670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/86000000/85480000/85480000/85479906/71c0d5d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming & Comfy Gem \~ 10 Mins to Downtown \~Patio!

[](https://www.expedia.ca/Chicago-Hotels-Charming-Comfy-Gem-10-Mins-To-Downtown-Patio.h85479906.Hotel-Information)

West Town

9.2/10

Wonderful

(10 reviews)

"Comfortable place in a convenient location. Very clean and had everything we needed."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise G.

[](https://www.expedia.ca/Chicago-Hotels-Charming-Comfy-Gem-10-Mins-To-Downtown-Patio.h85479906.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/114000000/113620000/113617700/113617635/1f74f620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/114000000/113620000/113617700/113617635/df0a1eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113620000/113617700/113617635/611bbca9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/114000000/113620000/113617700/113617635/6cf778de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Last-Minute Chicago home with Rooftop Views +Private HOT TUB -Garage-Sleeps 12

[](https://www.expedia.ca/Chicago-Hotels-RARE-12Guests-3BedRooms-PrivateHome-Full-Kitchen-SKYView-Roof-CarGarage-PETsOK.h113617635.Hotel-Information)

West Town

10/10

Exceptional

(3 reviews)

"Stayed in Chicago for a trade show. Great location and well kept property "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aaron E.

[](https://www.expedia.ca/Chicago-Hotels-RARE-12Guests-3BedRooms-PrivateHome-Full-Kitchen-SKYView-Roof-CarGarage-PETsOK.h113617635.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/28000000/27140000/27132600/27132548/d786248e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/28000000/27140000/27132600/27132548/7cd795d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/28000000/27140000/27132600/27132548/16581d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/28000000/27140000/27132600/27132548/63949d7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 4-Level/4-Bedroom Townhouse in West Loop

[](https://www.expedia.ca/Chicago-Hotels-Spacious-4-Level4-Bedroom-Townhouse-In-West-Loop.h27132548.Hotel-Information)

West Town

10/10

Exceptional

(63 reviews)

"We had a very nice experience and everyone was comfortable."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kirk D.

[](https://www.expedia.ca/Chicago-Hotels-Spacious-4-Level4-Bedroom-Townhouse-In-West-Loop.h27132548.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/107000000/106750000/106747000/106746988/352c007b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106750000/106747000/106746988/20d49ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/107000000/106750000/106747000/106746988/fedd8e07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/107000000/106750000/106747000/106746988/1f3667d6_edited_6700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chicago West Town Row House

[](https://www.expedia.ca/Chicago-Hotels-Chicago-West-Town-3-Bedroom-Row-House-In-Walking-Distance-To-Chicagos-West-Loop.h106746988.Hotel-Information)

West Town

9.8/10

Exceptional

(7 reviews)

"Thank you great place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura C.

[](https://www.expedia.ca/Chicago-Hotels-Chicago-West-Town-3-Bedroom-Row-House-In-Walking-Distance-To-Chicagos-West-Loop.h106746988.Hotel-Information)

![TV, fireplace, video games, DVD player](https://images.trvl-media.com/lodging/102000000/101930000/101922000/101921977/ea86715c_edited_d21d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/102000000/101930000/101922000/101921977/d8dce981.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101930000/101922000/101921977/3b545521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/102000000/101930000/101922000/101921977/28a95110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Banksy-King Bed-Firepit-Rooftop-United Center

[](https://www.expedia.ca/Chicago-Hotels-The-Banksy-King-Bed-Firepit-Rooftop-United-Center.h101921977.Hotel-Information)

Near West Side

10/10

Exceptional

(1 review)

[](https://www.expedia.ca/Chicago-Hotels-The-Banksy-King-Bed-Firepit-Rooftop-United-Center.h101921977.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/120000000/119850000/119840800/119840758/4f74a0bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/120000000/119850000/119840800/119840758/57259ccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/120000000/119850000/119840800/119840758/7851a000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/120000000/119850000/119840800/119840758/40078856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NEW! Spacious 3-Bed West Loop Townhouse, 1 Car Garage

[](https://www.expedia.ca/Chicago-Hotels-NEW-Spacious-3-Bed-West-Loop-Townhouse.h119840758.Hotel-Information)

Downtown Chicago

[](https://www.expedia.ca/Chicago-Hotels-NEW-Spacious-3-Bed-West-Loop-Townhouse.h119840758.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/122000000/121800000/121797700/121797661/a69912a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121800000/121797700/121797661/aece1639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/122000000/121800000/121797700/121797661/aa983951.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/122000000/121800000/121797700/121797661/6a80fbe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious Single Family House with Parking

[](https://www.expedia.ca/Chicago-Hotels-Spacious-Single-Family-House-With-Parking.h121797661.Hotel-Information)

Lower West Side

[](https://www.expedia.ca/Chicago-Hotels-Spacious-Single-Family-House-With-Parking.h121797661.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/101000000/100110000/100102100/100102076/34c9764c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100110000/100102100/100102076/93c7a77a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/101000000/100110000/100102100/100102076/f583f41d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/101000000/100110000/100102100/100102076/470e6b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Steps to Fulton Market Downtown 4 bedroom Entire Home Sleeps 11 with City Views

[](https://www.expedia.ca/Chicago-Hotels-Steps-To-Fulton-Market-Downtown-4-Bedroom-Entire-Home-Sleeps-11-With-City-Views.h100102076.Hotel-Information)

West Town

10/10

Exceptional

(3 reviews)

"Clean, spacious, and well equipped for renters. Our group enjoyed this home immensely and its easy walk to all Fulton Market attractions. Owner is thoughtful and very responsive. I hope to stay again next time I'm in the area!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

C D.

[](https://www.expedia.ca/Chicago-Hotels-Steps-To-Fulton-Market-Downtown-4-Bedroom-Entire-Home-Sleeps-11-With-City-Views.h100102076.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/122000000/121910000/121903000/121902920/f27b803e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/122000000/121910000/121903000/121902920/47edb64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Game room](https://images.trvl-media.com/lodging/122000000/121910000/121903000/121902920/60720dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/122000000/121910000/121903000/121902920/0bc61057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stylish 3BR Townhouse with 2 Jacuzzi and 1 private garage spot

[](https://www.expedia.ca/Chicago-Hotels-Stylish-3BR-Townhouse-With-2-Jacuzzi-And-1-Private-Garage-Spot.h121902920.Hotel-Information)

Downtown Chicago

[](https://www.expedia.ca/Chicago-Hotels-Stylish-3BR-Townhouse-With-2-Jacuzzi-And-1-Private-Garage-Spot.h121902920.Hotel-Information)

![Smart TV, video-game console, DVD player, books](https://images.trvl-media.com/lodging/45000000/44260000/44254800/44254790/474d8ff3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/45000000/44260000/44254800/44254790/3a9831ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/45000000/44260000/44254800/44254790/95eea910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video-game console, DVD player, books](https://images.trvl-media.com/lodging/45000000/44260000/44254800/44254790/1a193777.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bright, Cozy Apartment by Downtown & Train Stop; Great for Couples/Small Groups

[](https://www.expedia.ca/Chicago-Hotels-Bright.h44254790.Hotel-Information)

West Town

8.0/10

Very good

(2 reviews)

"To preface my review, I think this place definitely has the \*\*potential\*\* to be a 5 star stay. The location is phenomenal and the apartment as a whole is very nice. I really liked the TV in the bedroom since it was great to watch movies on it. However, this stay earns only 3 stars for the following reasons. First, when I arrived, Kam did not provide any directions on how to get into my apartment or where the apartment would be located within his building, even though I messaged him on VRBO a...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

nlFlkKQG1pqp9KasAAAAcDBuBgkqhkiG9w0BBwagYTBfAgEAMFoGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMGxVypzvdn9AM X.

[](https://www.expedia.ca/Chicago-Hotels-Bright.h44254790.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/105000000/104260000/104258600/104258571/a61dd182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104260000/104258600/104258571/08886b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/105000000/104260000/104258600/104258571/83ed45ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104260000/104258600/104258571/ec5fa7d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Single Family Home in the Heart of Chicago. By UIC, Medical District, Pilsen!

[](https://www.expedia.ca/Chicago-Hotels-Single-Family-Home-In-The-Heart-Of-Chicago-By-UIC.h104258571.Hotel-Information)

Near West Side

[](https://www.expedia.ca/Chicago-Hotels-Single-Family-Home-In-The-Heart-Of-Chicago-By-UIC.h104258571.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/121000000/120470000/120469100/120469097/25f1eced.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120470000/120469100/120469097/bce7764a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120470000/120469100/120469097/0d15fc77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120470000/120469100/120469097/58f5014d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NEW! Stylish 3BD/2.5BTH w/parking! United Center!

[](https://www.expedia.ca/Chicago-Hotels-NEW-Stylish-3BD25BTH-Wparking-United-Center.h120469097.Hotel-Information)

Near West Side

[](https://www.expedia.ca/Chicago-Hotels-NEW-Stylish-3BD25BTH-Wparking-United-Center.h120469097.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99380000/99377300/99377203/cf23e3a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/100000000/99380000/99377300/99377203/w1024h677x0y3-6e0a8747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/100000000/99380000/99377300/99377203/ef3805b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/100000000/99380000/99377300/99377203/w1014h683x5y0-ff2d3bee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful modern 3bed 3 bath duplex

[](https://www.expedia.ca/Chicago-Hotels-Beautiful-Modern-3bed-3-Bath-Duplex.h99377203.Hotel-Information)

West Town

[](https://www.expedia.ca/Chicago-Hotels-Beautiful-Modern-3bed-3-Bath-Duplex.h99377203.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-15&endDate=2026-02-16&regionId=6210751&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Illinois+Medical+District+Station%2C+Chicago%2C+Illinois%2C+United+States+of+America&regionId=6210751&latLong=41.875701%2C-87.672916&adults=2&startDate=2026-05-02&d1=2026-05-02&endDate=2026-05-05&d2=2026-05-05&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Illinois+Medical+District+Station%2C+Chicago%2C+Illinois%2C+United+States+of+America&regionId=6210751&latLong=41.875701%2C-87.672916&adults=2&startDate=2026-05-02&d1=2026-05-02&endDate=2026-05-05&d2=2026-05-05&lodging=APARTMENT)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Illinois+Medical+District+Station%2C+Chicago%2C+Illinois%2C+United+States+of+America&regionId=6210751&latLong=41.875701%2C-87.672916&adults=2&startDate=2026-05-02&d1=2026-05-02&endDate=2026-05-05&d2=2026-05-05&lodging=COTTAGE)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Illinois+Medical+District+Station%2C+Chicago%2C+Illinois%2C+United+States+of+America&regionId=6210751&latLong=41.875701%2C-87.672916&adults=2&startDate=2026-05-02&d1=2026-05-02&endDate=2026-05-05&d2=2026-05-05&lodging=CONDO)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Illinois+Medical+District+Station%2C+Chicago%2C+Illinois%2C+United+States+of+America&regionId=6210751&latLong=41.875701%2C-87.672916&adults=2&startDate=2026-05-02&d1=2026-05-02&endDate=2026-05-05&d2=2026-05-05&lodging=VILLA)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Illinois+Medical+District+Station%2C+Chicago%2C+Illinois%2C+United+States+of+America&regionId=6210751&latLong=41.875701%2C-87.672916&adults=2&startDate=2026-05-02&d1=2026-05-02&endDate=2026-05-05&d2=2026-05-05&lodging=VACATION_HOME)

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## Top Illinois Medical District Station Hotel Reviews

![The Royal Sonesta Chicago Downtown](https://images.trvl-media.com/lodging/1000000/20000/17600/17543/696a55e6_y.jpg)

### The Royal Sonesta Chicago Downtown

10/10 Excellent

"Amazing overall will be my go to every trip to Chicago "

[](https://expedia.ca/Chicago-Hotels-Royal-Sonesta-Chicago-Downtown.h17543.Hotel-Information)

![Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/1000000/30000/21200/21142/886bf093_y.jpg)

### Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

10/10 Excellent

"Good customer service prompt to help "

[](https://expedia.ca/Chicago-Hotels-Hotel-Blake.h21142.Hotel-Information)

![Eurostars Magnificent Mile](https://images.trvl-media.com/lodging/2000000/1890000/1880400/1880320/08bbf982_y.jpg)

### Eurostars Magnificent Mile

10/10 Excellent

"clean nice room, comfy bed, really nice rainfall and handheld showers, nice bathroom products. good location"

[](https://expedia.ca/Chicago-Hotels-Eurostars-Magnificent-Mile.h1880320.Hotel-Information)

![River Hotel](https://images.trvl-media.com/lodging/3000000/2680000/2675400/2675313/9a897fc5_y.jpg)

### River Hotel

10/10 Excellent

"Cleanroom"

[](https://expedia.ca/Chicago-Hotels-River-Hotel.h2675313.Hotel-Information)

![Aloft Chicago Mag Mile](https://images.trvl-media.com/lodging/27000000/27000000/26998800/26998765/d755f57e_y.jpg)

### Aloft Chicago Mag Mile

10/10 Excellent

"Great location and friendly staff. "

[](https://expedia.ca/Chicago-Hotels-Aloft-Chicago-Mag-Mile.h26998765.Hotel-Information)

![DoubleTree by Hilton Chicago - Magnificent Mile](https://images.trvl-media.com/lodging/1000000/30000/21200/21152/757dbd3e_y.jpg)

### DoubleTree by Hilton Chicago - Magnificent Mile

10/10 Excellent

"2nd time at hotel and will come again. "

[](https://expedia.ca/Chicago-Hotels-DoubleTree-By-Hilton-Chicago-Magnificent-Mile.h21152.Hotel-Information)

![Hotel Riu Plaza Chicago](https://images.trvl-media.com/lodging/103000000/102630000/102622800/102622712/3e21593f_y.jpg)

### Hotel Riu Plaza Chicago

10/10 Excellent

"Love the place! Great breakfast buffet. The room was clean, service was great, and great"

[](https://expedia.ca/Chicago-Hotels-Hotel-Riu-Plaza-Chicago.h102622712.Hotel-Information)

![Sable at Navy Pier Chicago, Curio Collection by Hilton](https://images.trvl-media.com/lodging/58000000/57660000/57651200/57651125/6c1738b5_y.jpg)

### Sable at Navy Pier Chicago, Curio Collection by Hilton

10/10 Excellent

"Great experience with no problems"

[](https://expedia.ca/Chicago-Hotels-Sable-At-Navy-Pier-Chicago.h57651125.Hotel-Information)

![Courtyard by Marriott Chicago Magnificent Mile](https://images.trvl-media.com/lodging/1000000/990000/982600/982517/529d8be8_y.jpg)

### Courtyard by Marriott Chicago Magnificent Mile

10/10 Excellent

"Everything was nice, from the atmosphere to the room. I enjoyed my stay "

[](https://expedia.ca/Chicago-Hotels-Courtyard-By-Marriott-Chicago-Magnificent-Mile.h982517.Hotel-Information)

## Find out more about Illinois Medical District Station

#### What types of Vacation Homes can I find in Illinois Medical District Station? 

When you’re looking for Illinois Medical District Station Vacation Homes in 2026, you can use Expedia’s filters to find accommodation that’s family-friendly or business-friendly, and narrow down your search results by amenities, price per night, and much more. For example, you can search for Vacation Homes that welcome pets, or one with accessibility features. You’ll find a range of places to stay to suit every budget, so if you're looking for cheap Vacation Homes in Illinois Medical District Station, use our simple search function to help you secure a good deal. If the exact location of Vacation Homes is important to you, try our map facility to view available places in relation to each other and to Illinois Medical District Station. 

#### How much do Vacation Homes cost in Illinois Medical District Station? 

Prices for Illinois Medical District Station Vacation Homes can start from as little as \* in 2026\. The cost per night varies depending on several factors, including the amenities on offer at Vacation Homes, the exact location of Vacation Homes and how far they are from Illinois Medical District Station, as well as how high the demand for accommodation is near Illinois Medical District Station on the dates of your booking. At Expedia, we cater for every budget, so if you’re looking for cheap Vacation Homes in Illinois Medical District Station, you can sleep easy knowing that we’ll help you to secure some of the very best deals on offer. 

#### How to find the best deals on Illinois Medical District Station Vacation Homes? 

Expedia’s search function can help you find a great deal on Illinois Medical District Station Vacation Homes. Changing the sort order of your search results can help you to find cheap Vacation Homes in Illinois Medical District Station at a glance. If you have a specific price range in mind, try selecting minimum and maximum prices per night to narrow your results. You can also filter by guest ratings and star ratings to find some of the best offers for Vacation Homes within your budget. Don’t forget, if you’re an Expedia Rewards member, you can use the ‘Member Prices’ filter to make instant savings on your booking.

#### Why should I choose Expedia to book Illinois Medical District Station Vacation Homes? 

 One of the many benefits of booking Illinois Medical District Station Vacation Homes with Expedia is the clear and simple search function. When you use the many filters on offer, you can easily compile a shortlist of fantastic places to stay, and make comparisons between the different Vacation Homes so that you can choose exactly what you need. At Expedia, it’s possible to create your own customized package and make great savings by booking flights, car hire, and more at the same time as Illinois Medical District Station Vacation Homes. And don’t forget that with free membership to Expedia Rewards, you can earn points on all eligible purchases, and build your points total to use towards future travel. 

#### What is the cancellation policy on booking Illinois Medical District Station Vacation Homes? 

 It’s often possible to change or cancel bookings at Illinois Medical District Station Vacation Homes without a fee, but it depends on the rules and restrictions of the various Vacation Homes. Many booking options offer a window of flexibility, for example a full refund if you cancel more than 24 or 48 hours before Illinois Medical District Station arrival dates. It’s best to check the policies of the individual Vacation Homes before making a booking, if flexibility is important to you. You can filter for the ‘Fully refundable’ payment type when you search for Vacation Homes. You can also view the terms of the different Vacation Homes at any time by checking the details of your booking at Expedia. 

\*Prices and availability are subject to change. Additional terms may apply 

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- [Flights from Toronto (YYZ) to Chicago (ORD) ](https://www.expedia.ca/lp/flights/yyz/ord/toronto-to-chicago)

- [Visit Downtown Chicago ](https://www.expedia.ca/Chicago-Downtown-Chicago.dx6350699)
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- [Chicago Vacations ](https://www.expedia.ca/Chicago.d178248.Destination-Travel-Guides)
- [United Center ](https://www.expedia.ca/United-Center-Near-West-Side.d6064077.Vacation-Attraction)

- [Car rentals near Chicago ](https://www.expedia.ca/Car-Rentals-In-Chicago.d178248.Car-Rental-Guide)
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- [West Side Vacation Rentals ](https://www.expedia.ca/West-Side-Vacation-Rentals.d553248635976475400.Travel-Guide-VacationRentals)

- [Things to do in Chicago ](https://www.expedia.ca/Things-To-Do-In-Chicago.d178248.Travel-Guide-Activities)

- [Book Vacation Homes in Illinois Medical District Station on Expedia.com ](https://www.expedia.com/Illinois-Medical-District-Station-Private-Vacation-Homes.d6210751-aaPrivateVacationHomes.Travel-Guide-Accommodation)