Photo by T McD

Hotels in Illinois Medical District, Chicago from CA $126

Most hotels are fully refundable. Because flexibility matters.

Save an average of 15% on thousands of hotels with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Illinois Medical District hotels and places to stay

Lobby
Silversmith Hotel Chicago Downtown
4.0 star property
9.4 out of 10, Exceptional, (1602)
"Enjoyed my stay here. It’s in the downtown loop making taking the train convenient. Many things are walkable nearby that are great for tourists. Staff was incredibly friendly and helpful!"
The price is CA $219
CA $289 total
includes taxes & fees
May 27 - May 28
Silversmith Hotel Chicago Downtown
Terrace/patio
citizenM Chicago Downtown
4.0 star property
9.2 out of 10, Wonderful, (1349)
"Great location in downtown Chicago, this is my second stay with citizens M and the one in seatle was the same satisfaction for me. "
The price is CA $171
CA $201 total
includes taxes & fees
May 27 - May 28
citizenM Chicago Downtown
Lobby
LondonHouse Chicago, Curio Collection by Hilton
4.5 star property
9.2 out of 10, Wonderful, (3516)
"Location was fantastic and the property is beautiful!"
The price is CA $179
CA $210 total
includes taxes & fees
May 27 - May 28
LondonHouse Chicago, Curio Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in
Terrace/patio
Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
9.2 out of 10, Wonderful, (1897)
"Everything was great!! I’d stay here again for sure. "
The price is CA $289
CA $339 total
includes taxes & fees
May 28 - May 29
Sable at Navy Pier Chicago, Curio Collection by Hilton
Rooftop terrace
Virgin Hotels Chicago
4.5 star property
9.2 out of 10, Wonderful, (1004)
"We have a plenty staying at this hotel has the best locations and restaurant is so good "
The price is CA $280
CA $369 total
includes taxes & fees
May 27 - May 28
Virgin Hotels Chicago
Terrace/patio
Trump International Hotel & Tower Chicago
5.0 star property
9.2 out of 10, Wonderful, (1190)
"The best hotel hands down!"
The price is CA $505
CA $593 total
includes taxes & fees
May 23 - May 24
Trump International Hotel & Tower Chicago
Exterior
Loews Chicago Hotel
4.5 star property
9.2 out of 10, Wonderful, (1510)
"Fantastic property!!"
The price is CA $230
CA $313 total
includes taxes & fees
May 27 - May 28
Loews Chicago Hotel
Exterior
Hyatt Regency Chicago
4.0 star property
9.0 out of 10, Wonderful, (3489)
"Over all I had a great experience. The room itself was very noisy. I could hear people next to me and above me. The hallway was very noisy too. "
The price is CA $318
CA $414 total
includes taxes & fees
May 27 - May 28
Hyatt Regency Chicago
Exterior
The Royal Sonesta Chicago Downtown
4.0 star property
9.0 out of 10, Wonderful, (1925)
"The valet parking helper could be more pleasant when returning the car"
The price is CA $244
CA $327 total
includes taxes & fees
May 27 - May 28
The Royal Sonesta Chicago Downtown
Cocktail bar
ACME Hotel Company
3.5 star property
9.0 out of 10, Wonderful, (1406)
"LOCATION!! Best location in the city, near everything and felt safe also. Everyone very friendly and helpful. Rooms pretty comfortable, clean and chic. "
The price is CA $171
CA $201 total
includes taxes & fees
May 27 - May 28
ACME Hotel Company
Exterior
Hyatt Place Chicago/River North
3.5 star property
9.0 out of 10, Wonderful, (1379)
"It was amazing. "
The price is CA $208
CA $244 total
includes taxes & fees
May 27 - May 28
Hyatt Place Chicago/River North
Exterior
InterContinental Chicago Magnificent Mile, an IHG Hotel
4.5 star property
8.8 out of 10, Excellent, (1585)
"This has become my go to place when I am in Chicago. The staff is so nice The new restaurant Casa chi was so good."
The price is CA $257
CA $345 total
includes taxes & fees
May 27 - May 28
InterContinental Chicago Magnificent Mile, an IHG Hotel
Aerial view
Holiday Inn Chicago Dwtn Wolf Point, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, (1004)
"Comfortable stay friendly staff"
The price is CA $218
CA $256 total
includes taxes & fees
May 27 - May 28
Holiday Inn Chicago Dwtn Wolf Point, an IHG Hotel
Lobby
Hyatt Centric Chicago Magnificent Mile
4.0 star property
8.8 out of 10, Excellent, (1297)
"The hotel was fine. It is extremely central to most usual tourist activities and worked really well in that regard. It has a weird entryway that you enter on the ground floor that is not the hotel and you go up a floor or so and then enter the hotel lobby. They have disposable plastic cups further wrapped in plastic instead of real drinking glasses. This was unusual and felt cheap. They have paper cups instead of real coffee cups which is less uncommon. Both of these felt eco unfriendly....
The price is CA $238
CA $307 total
includes taxes & fees
May 27 - May 28
Hyatt Centric Chicago Magnificent Mile
Daily cooked-to-order breakfast for a fee
Aloft Chicago Mag Mile
3.0 star property
8.6 out of 10, Excellent, (2199)
"It was a perfect location "
The price is CA $178
CA $209 total
includes taxes & fees
May 27 - May 28
Aloft Chicago Mag Mile
Exterior
Club Quarters Hotel, Central Loop, Chicago
4.0 star property
8.6 out of 10, Excellent, (3051)
"Customer service at front desk was friendly and great "
The price is CA $195
CA $229 total
includes taxes & fees
May 27 - May 28
Club Quarters Hotel, Central Loop, Chicago
Front of property - evening/night
Fairmont Chicago at Millennium Park
4.5 star property
8.6 out of 10, Excellent, (1487)
"Requested a fridge and microwave, as they do not come in each room. Wasn't there when we checked in, but came shortly and worked well. Nice hotel, but no pool and they only offer parking as a valet service for $80+ per day. Ended up parking at Aon Center for $17/day, which was VERY close. "
The price is CA $257
CA $336 total
includes taxes & fees
May 28 - May 29
Fairmont Chicago at Millennium Park
Rooftop bar, alfresco dining, open daily
The Godfrey Hotel Chicago
4.5 star property
8.6 out of 10, Excellent, (1533)
"The room was extremely comfortable and once we figured out the location we realized we were accessible to a lot of amenities such as shopping, restaurants, The Pier"
The price is CA $230
CA $302 total
includes taxes & fees
May 27 - May 28
The Godfrey Hotel Chicago
Terrace/patio
Home2 Suites by Hilton Chicago River North
3.0 star property
8.4 out of 10, Very good, (1489)
"Nice location, nice staff."
The price is CA $219
CA $257 total
includes taxes & fees
May 27 - May 28
Home2 Suites by Hilton Chicago River North
Balcony
Eurostars Magnificent Mile
4.0 star property
8.4 out of 10, Very good, (1930)
"Very nice and clean! Great customer service."
The price is CA $245
CA $287 total
includes taxes & fees
May 27 - May 28
Eurostars Magnificent Mile
Don't see what you're looking for?
See all available properties in Illinois Medical District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Illinois Medical District

Hotels in top Chicago neighborhoods Learn more about Illinois Medical District

Illinois Medical District Travel Info

Location
Chicago, United States of America
Similar neighborhoods
Central Chicago, Magnificent Mile and The Loop
Number of hotels
4,293
Known landmarks
Art Institute of Chicago, Chicago Riverwalk and Chicago Theatre

Frequently asked questions

What's it like in Illinois Medical District?

Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer. Consider a visit to Anna and Frederick Douglass Park as part of your Illinois Medical District travel plans.

Where is the best place to stay in Illinois Medical District?

Based on Expedia customer reviews, Hyatt House Chicago Medical/University District is the highest ranked property in Illinois Medical District. This hotel is a short 12-minute walk from United Center, and it offers free breakfast and a 24-hour fitness center. Another top choice in the area is Hyatt Place Chicago Medical/University District.

How many hotels are there in the Illinois Medical District area?

If you're searching for places to stay in Chicago, choose from one of Expedia's 14 hotels and other accommodations in Illinois Medical District.

If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?

Yes! Most hotel reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.

Where can I learn more about changing or cancelling my trip to Illinois Medical District?

To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page.

What can I see and do in this Chicago neighborhood?

Anna and Frederick Douglass Park is an attraction you might want to check out while you're in Illinois Medical District. When you're sightseeing in Chicago, Grant Park and United Center are also worth a stop.

How can I get around Illinois Medical District and the greater Chicago area?

Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.

Recent Reviews in Illinois Medical District