Title: Book the Best Houston Museum District SPA Resorts from CA $402 - Spa Hotels in Houston Museum District, Houston | Expedia.ca [Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Houston Museum District Car Rentals](https://expedia.ca/Car-Rentals-In-Houston-Museum-District.d6164045.Car-Rental-Guide)[Houston Museum District Vacations](https://expedia.ca/Houston-Museum-District.d6164045.Destination-Travel-Guides) ![Hermann Park featuring a garden and landscape views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23515-Hermann-Park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Houston Museum District, Houston from CA $402 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Houston Museum District Spa Hotels Tonight [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2025-10-01&endDate=2025-10-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2025-10-02&endDate=2025-10-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Houston Museum District Spa Hotels ![Spa](https://images.trvl-media.com/lodging/89000000/88660000/88655200/88655108/4d2461d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88660000/88655200/88655108/c0dd4425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88660000/88655200/88655108/1d346d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, offices](https://images.trvl-media.com/lodging/89000000/88660000/88655200/88655108/w2044h1360x4y2-38ccb9e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Home near Medical Center South Central Houston 9.4/10 Exceptional (3) CA $244 CA $596 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Houston-Hotels-Modern-Home-Near-Medical-Center.h88655108.Hotel-Information) ![6 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/67000000/66900000/66900000/66899979/467d40a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66900000/66900000/66899979/b6074bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/67000000/66900000/66900000/66899979/df9df971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/67000000/66900000/66900000/66899979/7c83ac8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The White House in Museum Park 6 Bed 6 Bath Ensuite Elegant Classic home South Central Houston 9.2/10 Wonderful (19) "What an incredible old house! Large and comfortable for all seven of us! Well appointed kitchen, living room for hanging out and everyone had their own bathroom. There were a few drawbacks; moldy smell throughout, rough neighborhood, and lacking details such as decor, hooks/racks in bathrooms and polyester sheets." [](https://www.expedia.ca/Houston-Hotels-The-White-House-In-Museum-Park-6-Bed-6-Bath-Ensuite-Elegant-Classic-Home.h66899979.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66380000/66370800/66370797/30f8861a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66380000/66370800/66370797/df3de9ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66380000/66370800/66370797/5dbaa7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/67000000/66380000/66370800/66370797/w3596h2399x3y0-16246e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Museum District - Beautiful 2 Br/2Ba with King bed! South Central Houston 9.4/10 Exceptional (19) "Great location, very clean, comfortable beds and offstreet parking. Would stay there again." CA $160 CA $370 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Houston-Hotels-Museum-District-Newly-Updated-2-Br2Ba-King-Bed.h66370797.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/94000000/93550000/93544700/93544699/c5ba2c7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/94000000/93550000/93544700/93544699/b7643388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93550000/93544700/93544699/ecda046c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/94000000/93550000/93544700/93544699/817cc680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Museum District - 3Br/2Ba Sunny apartment with King Bed South Central Houston 9.2/10 Wonderful (11) "Flawless experience! Lovely apartment and very responsive host." CA $160 CA $402 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Houston-Hotels-Museum-District-3Br2Ba-Sunny-Apartment-With-King-Bed.h93544699.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/31000000/30450000/30449300/30449260/e8a44b15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30450000/30449300/30449260/9ae59571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/31000000/30450000/30449300/30449260/d20eaf5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/31000000/30450000/30449300/30449260/bdab0b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super location, luxury rental South Central Houston 10/10 Exceptional (52) "We enjoyed everything & will be back, thanks Daniela!" [](https://www.expedia.ca/Houston-Hotels-Super-Location.h30449260.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/111230000/111222700/111222660/0a6b86b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111230000/111222700/111222660/63fe9632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111230000/111222700/111222660/ce330a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111230000/111222700/111222660/23d25cf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity Studios: Near Medical Center & Museum District South Central Houston 10/10 Exceptional (1) "The place was as expected. It worked great for my wife and I while visiting our daughter." CA $100 CA $455 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Houston-Hotels-Serenity-Studios-Your-Peaceful-Retreat-Near-The-Museum-District-Med-Center.h111222660.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99820000/99811800/99811775/6fcb2880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/100000000/99820000/99811800/99811775/49a1536e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/100000000/99820000/99811800/99811775/e13361c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99820000/99811800/99811775/b6061125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Velouté Valor: 1BD Near Medical Center & Museum District South Central Houston 8.0/10 Very good (1) "Nice clean unit. Expected to be closer to the museums. They were not walking distance for me." CA $114 CA $479 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Houston-Hotels-1-BD-Luxury-Retreat-Museum-District-Downtown-HTX.h99811775.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/33000000/32890000/32885900/32885845/dc4a8900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/33000000/32890000/32885900/32885845/fbe0e6d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/33000000/32890000/32885900/32885845/481aad82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32890000/32885900/32885845/44d0e770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### UV Air Purification | Medical District | Restaurants | Parks | Kid Friendly South Central Houston 10/10 Exceptional (15) "Location was amazing! Right next to the childrens museum, Herman park, and the science museum. Everything was kid friendly and we enjoyed our stay." [](https://www.expedia.ca/Houston-Hotels-UV-Air-Purification-Medical-District-Restaurants-Parks-Kid-Friendly.h32885845.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69690000/69680100/69680095/310cde98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69690000/69680100/69680095/018c146f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/70000000/69690000/69680100/69680095/59287f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/70000000/69690000/69680100/69680095/e600baca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### A Studio At Heart of Houston Museum District South Central Houston 10/10 Exceptional (2) "My stay has been great." [](https://www.expedia.ca/Houston-Hotels-A-Studio-At-Heart-Of-Houston-Museum-District.h69680095.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89160000/89152400/89152334/w1125h748x0y0-78476aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89160000/89152400/89152334/w1125h745x0y0-c34ddd86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89160000/89152400/89152334/642a1670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/90000000/89160000/89152400/89152334/92e677df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mind Body Spirit Zen Joint South Central Houston [](https://www.expedia.ca/Houston-Hotels-Mind-Body-Spirit-Zen-Joint.h89152334.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-15&endDate=2025-10-16®ionId=6164045&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Houston Museum District ### Top Houston Museum District attractions for a relaxing vacation In the heart of the Houston Museum District, the allure of culture and relaxation harmoniously intertwines, making it an exciting spot for travellers seeking spa hotels. Start your journey at the renowned Museum of Fine Arts, where you can immerse yourself in a diverse collection of art from around the world, followed by a tranquil stroll through the nearby sculpture garden. The Houston Museum of Natural Science is perfect for families, featuring engaging exhibits and a stunning planetarium that will captivate both children and adults alike. After a day of exploration, unwind at the tranquil Hermann Park, offering peaceful lakes and picturesque walking trails—ideal for a leisurely afternoon. Don’t miss the Contemporary Arts Museum, which hosts thought-provoking exhibitions and innovative installations, providing a perfect blend of culture and relaxation. Staying at a spa hotel in this vibrant area allows you to indulge in luxurious treatments that rejuvenate your spirit after a day of adventure. Many hotels offer easy access to local attractions, so you can effortlessly balance your exploration with pampering sessions, ensuring your stay is both enriching and deeply relaxing. Enjoy personalised service and the convenience of being steps away from Houston's vibrant cultural scene. ## Top Houston Museum District Hotel Reviews ![Hilton Americas-Houston](//images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Very beautiful hotel" [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](//images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 10/10 Excellent "Very good" [](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![Marriott Marquis Houston](//images.trvl-media.com/lodging/15000000/14990000/14986100/14986044/4666f7f4_y.jpg) ### Marriott Marquis Houston 10/10 Excellent "Good" [](https://expedia.ca/Houston-Hotels-Marriott-Marquis-Houston.h14986044.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "We stayed here with kids for Astros game. Loved the convenience to walk to Astros games, park downtown and metro! Lived the nightly complimentary milk and cookies. Also, loved the rooftop pool and the gym " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![The Royal Sonesta Houston Galleria](//images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "I always have a wonderful day at this hotel" [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Omni Houston Hotel](//images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg) ### Omni Houston Hotel 10/10 Excellent "Really enjoyed my stay. " [](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Houston Museum District? > Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers recommend the museums and gourmet restaurants in Houston Museum District—your day tour starts here. Be sure to pay a visit to the art galleries during your stay. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation. ### What's there to see and do in Houston Museum District? > Experience Houston Museum District with a stop at Houston Zoo, Children's Museum of Houston, and Houston Natural Science Museum. If you have a little extra time during your trip, you might want to make a stop at Houston Museum of Fine Arts and Health Museum. ### What is a Houston Museum District spa hotel? > Spa hotels in Houston Museum District provide lodging and have a full on-site spa offering services such as therapies and beauty treatments. Some also offer in-room treatments. 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[Museum Park Hotels](https://www.expedia.ca/Museum-Park-Houston-Hotels.0-n553248635976385848-0.Travel-Guide-Filter-Hotels) - [Hotels near Rice Stadium](https://www.expedia.ca/Rice-Stadium-Hotels.0-l6091875-0.Travel-Guide-Filter-Hotels) - [Hotels near Rice University](https://www.expedia.ca/Rice-University-Hotels.0-l501268-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Riverside Terrace](https://www.expedia.ca/Riverside-Terrace-Houston-Hotels-Luxury-Hotel.0-n151857-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Riverside Terrace Hotels](https://www.expedia.ca/Riverside-Terrace-Houston-Hotels.0-n151857-0.Travel-Guide-Filter-Hotels) - [Hotels near Rothko Chapel](https://www.expedia.ca/Rothko-Chapel-Hotels.0-l501261-0.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Adults-Only-Resorts.0-n553248635976476176-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-All-Inclusive-Hotel.0-n553248635976476176-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Beach-Hotel.0-n553248635976476176-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Boutique-Hotel.0-n553248635976476176-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Casino-Hotel.0-n553248635976476176-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Cheap-Hotels.0-n553248635976476176-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts and in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Honeymoon-Hotels.0-n553248635976476176-0-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Hotels-With-A-Lazy-River.0-n553248635976476176-0-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Hotels-With-Free-Parking.0-n553248635976476176-0-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Hotels-With-Indoor-Pool.0-n553248635976476176-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Hotels-With-Kitchenettes.0-n553248635976476176-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Luxury Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Luxury-Hotel.0-n553248635976476176-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Pet-Friendly-Hotel.0-n553248635976476176-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Shopping Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Shopping-Hotel.0-n553248635976476176-0-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Spa-Hotel.0-n553248635976476176-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [South Central Houston Hotels](https://www.expedia.ca/South-Central-Houston-Houston-Hotels.0-n553248635976476176-0.Travel-Guide-Filter-Hotels) - [Budget Host Hotels in Southgate](https://www.expedia.ca/Southgate-Houston-Hotels-Budget-Host.0-n553248635976470716-0--bBudgetHost.Travel-Guide-Filter-Hotels) - [Southgate Hotels](https://www.expedia.ca/Southgate-Houston-Hotels.0-n553248635976470716-0.Travel-Guide-Filter-Hotels) - [Farmstay in TMC Transit Center](https://www.expedia.ca/TMC-Transit-Center-Agritourism.d6211673-aaAgritourism.Travel-Guide-Accommodation) - [Hotels near Texas Children's Hospital](https://www.expedia.ca/Texas-Childrens-Hospital-Hotels.0-l553248635389801905-0.Travel-Guide-Filter-Hotels) - 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[Visit Greater Third Ward](https://www.expedia.ca/Houston-Greater-Third-Ward.dx553248635976008254) - [Houston Museum of Fine Arts](https://www.expedia.ca/Houston-Museum-Of-Fine-Arts-South-Central-Houston.d501255.Vacation-Attraction) - [Visit South Central Houston](https://www.expedia.ca/Houston-South-Central-Houston.dx553248635976476176) - [Visit Texas Medical Center](https://www.expedia.ca/Houston-Texas-Medical-Center.dx6143504) - [James Turrell's Twilight Epiphany Skyscape](https://www.expedia.ca/James-Turrells-Twilight-Epiphany-Skyscape-South-Central-Houston.d553248621532644481.Vacation-Attraction) - [Md Anderson Cancer Center](https://www.expedia.ca/MD-Anderson-Cancer-Center-Texas-Medical-Center.d6248539.Vacation-Attraction) - [Menil Collection](https://www.expedia.ca/Menil-Collection-Montrose.d501254.Vacation-Attraction) - [Rothko Chapel](https://www.expedia.ca/Rothko-Chapel-Montrose.d501261.Vacation-Attraction) - [Car rentals near Houston](https://www.expedia.ca/Car-Rentals-In-Houston.d178265.Car-Rental-Guide) - [Things to do in Houston](https://www.expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities) - [Book Hotels in Houston Museum District on Expedia.com](https://www.expedia.com/Houston-Museum-District-Houston-Hotels-Spa-Hotel.0-n6164045-0-tSpaHotel.Travel-Guide-Filter-Hotels)