Photo by Sean Hayes

Hillsborough Vacation Rentals

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Sep 5 - Sep 7
In one month
Sep 19 - Sep 21
In two months
Oct 17 - Oct 19
In three months
Nov 14 - Nov 16

Browse Select Hillsborough Vacation Homes

Our top choices for Hillsborough vacation homes

Urban Oasis w/ King Bed – 3 BR Near Duke & DT
Fridge, microwave, oven, stovetop

Urban Oasis w/ King Bed – 3 BR Near Duke & DT

10.0 out of 10, Exceptional, (22)
"Great stay and location"
The price is CA $158
CA $466 total
includes taxes & fees
Aug 27 - Aug 28
Urban Oasis w/ King Bed – 3 BR Near Duke & DT
⭐️ MODERN DURHAM RETREAT ⭐️ 🐕📚🏊‍♀️🏙🏥🛍🏟🍔🥂 CLOSE
Fridge, microwave, oven, stovetop

⭐️ MODERN DURHAM RETREAT ⭐️ 🐕📚🏊‍♀️🏙🏥🛍🏟🍔🥂 CLOSE

10.0 out of 10, Exceptional, (40)
"Place was clean and owner was very responsive. "
⭐️ MODERN DURHAM RETREAT ⭐️ 🐕📚🏊‍♀️🏙🏥🛍🏟🍔🥂 CLOSE
Modern Farmhouse Style, 4-bedroom home, downtown Durham, large private yard
Smart TV

Modern Farmhouse Style, 4-bedroom home, downtown Durham, large private yard

10.0 out of 10, Exceptional, (6)
"Enjoyed our stay. Location was great for graduation weekend. Easy walk to Hiwire. Host was very responsive and accommodating. "
The price is CA $175
CA $496 total
includes taxes & fees
Sep 2 - Sep 3
Modern Farmhouse Style, 4-bedroom home, downtown Durham, large private yard
★2024 MODERN NEWLY RANOVATED⭑4BR⭑NEAR RTP & RDU
Fridge, microwave, oven, stovetop

★2024 MODERN NEWLY RANOVATED⭑4BR⭑NEAR RTP & RDU

9.6 out of 10, Exceptional, (13)
"Nice neighborhood and home"
★2024 MODERN NEWLY RANOVATED⭑4BR⭑NEAR RTP & RDU
Charming parkview from rocking chair front porch
Fridge, microwave, oven, stovetop

Charming parkview from rocking chair front porch

9.2 out of 10, Wonderful, (25)
"Property is older, but we find that charming. Park across the street made it easy with our dog. Highly recommend "
The price is CA $93
CA $275 total
includes taxes & fees
Sep 2 - Sep 3
Charming parkview from rocking chair front porch
Homey Maple
Fridge, microwave, oven, stovetop

Homey Maple

The price is CA $139
CA $320 total
includes taxes & fees
Sep 1 - Sep 2
Homey Maple
Sweet Summertime on the Lake: Modern Home near Hyco
Fridge, microwave, oven, stovetop

Sweet Summertime on the Lake: Modern Home near Hyco

10.0 out of 10, Exceptional, (22)
"This place on LakeHyco was a nice place to stay before and aftr"
The price is CA $180
CA $446 total
includes taxes & fees
Aug 25 - Aug 26
Sweet Summertime on the Lake: Modern Home near Hyco
Cozy & relaxing cottage on the lake *Dog Friendly*
Dining

Cozy & relaxing cottage on the lake *Dog Friendly*

9.8 out of 10, Exceptional, (73)
"We had a mini family reunion here and it was perfect! House was exactly what we wanted and the outside space was amazing! "
The price is CA $144
CA $499 total
includes taxes & fees
Aug 21 - Aug 22
Cozy & relaxing cottage on the lake *Dog Friendly*
Luxurious Private Home w/Game Room @ Heart of RTP!
Pool

Luxurious Private Home w/Game Room @ Heart of RTP!

9.8 out of 10, Exceptional, (81)
"Our family enjoyed a great few days here. The big bathtub was perfect for the kids. "
Luxurious Private Home w/Game Room @ Heart of RTP!
Great for Family & Work - Near Duke & Hospital
Terrace/patio

Great for Family & Work - Near Duke & Hospital

9.4 out of 10, Exceptional, (51)
"Great location. Clean, soft sheets and very cozy beds. Had everything I needed. Perfect! "
The price is CA $158
CA $385 total
includes taxes & fees
Aug 25 - Aug 26
Great for Family & Work - Near Duke & Hospital
Luxe Home 4 Mins to Duke, DPAC, Downtown Durham | King Beds, Pool, Fire Pit, BBQ, Pet OK
Pool

Luxe Home 4 Mins to Duke, DPAC, Downtown Durham | King Beds, Pool, Fire Pit, BBQ, Pet OK

10.0 out of 10, Exceptional, (16)
"Beautiful property! Great host that really goes above and beyond other rentals."
The price is CA $298
CA $852 total
includes taxes & fees
Aug 27 - Aug 28
Luxe Home 4 Mins to Duke, DPAC, Downtown Durham | King Beds, Pool, Fire Pit, BBQ, Pet OK
COZY SUN FILLED HOME / MODERN VILLA NEAR DOWNTOWN
Interior

COZY SUN FILLED HOME / MODERN VILLA NEAR DOWNTOWN

10.0 out of 10, Exceptional, (62)
"Great stop for our medical stay at Duke."
The price is CA $218
CA $588 total
includes taxes & fees
Aug 21 - Aug 22
COZY SUN FILLED HOME / MODERN VILLA NEAR DOWNTOWN
Charming 2-bedroom house in fabulous Durham - close to Duke, downtown and UNC
Interior

Charming 2-bedroom house in fabulous Durham - close to Duke, downtown and UNC

10.0 out of 10, Exceptional, (3)
"What a sweet spot for getting away! We enjoyed the sunroom and spacious living/dining room, as well as the generous bedrooms. Responsive, friendly host. Very easy check-in/check-out. Would be happy to stay here again."
Charming 2-bedroom house in fabulous Durham - close to Duke, downtown and UNC
Discover Durham, just a quick 11-minutes from Duke University
Fridge, microwave, oven, stovetop

Discover Durham, just a quick 11-minutes from Duke University

10.0 out of 10, Exceptional, (34)
"Our job got extended a few days and this was the perfect place to round out the trip in Durham. I would definitely stay there again. "
Discover Durham, just a quick 11-minutes from Duke University
A natural oasis and architectural wonder in Chapel Hill
Interior

A natural oasis and architectural wonder in Chapel Hill

10.0 out of 10, Exceptional, (19)
"Different family members came into town to meet up for a baby shower in Cary. The house was perfect for us 4 couples and two grandchildren. Jackson, aged 4, had the best time playing with his small monster trucks on the rocks inside the house. It was so magical and the house itself is really unique. Beds super comfortable and the house had everything we needed. "
A natural oasis and architectural wonder in Chapel Hill
Newly Renovated Modern Farmhouse, 10mins Duke and 15mins UNC & RTP
Interior

Newly Renovated Modern Farmhouse, 10mins Duke and 15mins UNC & RTP

10.0 out of 10, Exceptional, (16)
"Good property and good property owner. She was communicative and responded quickly. We would stay there again."
Newly Renovated Modern Farmhouse, 10mins Duke and 15mins UNC & RTP
Tranquil Light-Filled Retreat 3BR Ranch
TV, offices

Tranquil Light-Filled Retreat 3BR Ranch

"Very nice and peaceful stay.Great accommodations!"
The price is CA $305
CA $735 total
includes taxes & fees
Sep 18 - Sep 19
Tranquil Light-Filled Retreat 3BR Ranch
Dog Friendly House Near Duke + Downtown + Airport
Fridge, microwave, oven, stovetop

Dog Friendly House Near Duke + Downtown + Airport

10.0 out of 10, Exceptional, (8)
"We enjoyed the stay and especially enjoyed the large dining room as we gathered for a family holiday. "
The price is CA $132
CA $441 total
includes taxes & fees
Aug 24 - Aug 25
Dog Friendly House Near Duke + Downtown + Airport
Chapel Hill/Durham retreat; hot tub, massage chair, massaging shower.
Property grounds

Chapel Hill/Durham retreat; hot tub, massage chair, massaging shower.

The price is CA $106
CA $279 total
includes taxes & fees
Aug 24 - Aug 25
Chapel Hill/Durham retreat; hot tub, massage chair, massaging shower.
Charming 6 bedroom home in Durham for your perfect getaway. 10 Min Walk to Duke.
Exterior

Charming 6 bedroom home in Durham for your perfect getaway. 10 Min Walk to Duke.

10.0 out of 10, Exceptional, (1)
"Such an amazing property with amazing hosts. We left something really important and they were able to ship it back to us. Total lifesaver!"
Charming 6 bedroom home in Durham for your perfect getaway. 10 Min Walk to Duke.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Hillsborough Hotel Reviews

University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

10/10 Excellent
"Enjoyed my stay!"
Carol 2-night trip
Posted 3 hours ago
University Inn Durham next to Duke University Medical Center