Title: Book the Best Herculaneum LUXURY Hotels - Upscale Hotels in Herculaneum, MO | Expedia.ca [Hotels in Herculaneum](https://expedia.ca/Herculaneum-Hotels.d3000349395.Travel-Guide-Hotels)[Vacation Rentals in Herculaneum](https://expedia.ca/Herculaneum-Vacation-Rentals.d3000349395.Travel-Guide-VacationRentals)[Flights to Herculaneum](https://expedia.ca/Cheap-Flights-To-Herculaneum.d3000349395.Travel-Guide-Flights)[Herculaneum Car Rentals](https://expedia.ca/Car-Rentals-In-Herculaneum.d3000349395.Car-Rental-Guide)[Herculaneum Vacation Packages](https://expedia.ca/Herculaneum.d3000349395.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Herculaneum, MO - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Herculaneum Luxury Hotels Tonight [Nov 9 - Nov 10](https://www.expedia.ca/Hotel-Search?regionId=3000349395&startDate=2025-11-09&endDate=2025-11-10&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 10 - Nov 11](https://www.expedia.ca/Hotel-Search?regionId=3000349395&startDate=2025-11-10&endDate=2025-11-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000349395&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=3000349395&startDate=2025-11-21&endDate=2025-11-23&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Herculaneum Luxury Hotels ## Top Herculaneum Hotel Reviews ![Drury Inn & Suites St. Louis Arnold](//images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/a7778b87_y.jpg) ### Drury Inn & Suites St. Louis Arnold 10/10 Excellent "Such friendly and accommodating staff! Spacious room. " [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) ![River City Casino & Hotel](//images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/33f9207d_y.jpg) ### River City Casino & Hotel 10/10 Excellent "Clean room, good Pizza. " [](https://expedia.ca/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) ![Best Western St. Louis Inn](//images.trvl-media.com/lodging/1000000/70000/63700/63684/00b04c50_y.jpg) ### Best Western St. Louis Inn 10/10 Excellent "The hotel is very clean and in a great location. The breakfast menu was varied — they offered eggs, sausage, pancakes, yogurt, coffee, juices, everything. It was a very good breakfast, and the staff was very friendly" [](https://expedia.ca/St-Louis-Hotels-Best-Western-St-Louis-Inn.h63684.Hotel-Information) ![Americas Best Value Inn St. Louis South](//images.trvl-media.com/lodging/1000000/60000/50100/50021/206c45d6_y.jpg) ### Americas Best Value Inn St. Louis South 10/10 Excellent "Clean room helpful and friendly staff! It was quiet at night! I really enjoyed my stay!" [](https://expedia.ca/St-Louis-Hotels-Americas-Best-Value-Inn-St-Louis-South.h50021.Hotel-Information) ![Hampton Inn & Suites St. Louis/South I-55](//images.trvl-media.com/lodging/4000000/3790000/3787100/3787094/8b6f2fed_y.jpg) ### Hampton Inn & Suites St. Louis/South I-55 10/10 Excellent "Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff." [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-StLouis-South-At-I-55.h3787094.Hotel-Information) ![Comfort Inn Festus - St Louis South](//images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc_y.jpg) ### Comfort Inn Festus - St Louis South 10/10 Excellent " Mika went above and beyond even getting us ice when we checked in. As I was checking out Gary fell out used.Mika got him up and inside. Got ice and bandages. We were soon on our way." [](https://expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Super 8 by Wyndham Waterloo](//images.trvl-media.com/lodging/1000000/860000/856400/856305/54de1823_y.jpg) ### Super 8 by Wyndham Waterloo 10/10 Excellent "Poor breakfast selection and towels were falling apart " [](https://expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-Waterloo.h856305.Hotel-Information) ![Baymont by Wyndham Festus](//images.trvl-media.com/lodging/1000000/10000/5600/5523/5f8a3296_y.jpg) ### Baymont by Wyndham Festus 10/10 Excellent "Great place to stay " [](https://expedia.ca/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury holiday in Herculaneum? > Let Expedia help you arrange your flight to St. Louis, MO (SUS-Spirit of St. Louis) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a vacation, so we make it easy to get what you need to make your stay special. If you want a posh hotel that has fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Herculaneum has to offer. Herculaneum has some interesting things to see and do including Mississippi River and Dunklin-Fletcher Memorial Park, so you might want to take in the local sights during your visit. ### When can I expect good weather in Herculaneum? > Planning for the weather is a good way to make your trip to Herculaneum relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Herculaneum is 52 inches. ### What's there to see and do in Herculaneum? > Take in the sights and attractions that Herculaneum offers with a visit to Mississippi River, Dunklin-Fletcher Memorial Park, and Indian Foot Lake. If you have a bit of extra time while you're in the area, you might want to check out Villa Antonio Winery and Lake Lorraine. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Aparthotels in Arnold](https://www.expedia.ca/Arnold-Apart-Hotels.d177608-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Arnold](https://www.expedia.ca/Arnold-Bed-And-Breakfast.d177608-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Chalets in Arnold](https://www.expedia.ca/Arnold-Chalets.d177608-aaChalets.Travel-Guide-Accommodation) - [Cheap Hotels in Arnold](https://www.expedia.ca/Arnold-Hotels-Cheap-Hotels.0-0-d177608-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Arnold](https://www.expedia.ca/Arnold-Hotels-Hotels-With-Hot-Tubs.0-0-d177608-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Arnold](https://www.expedia.ca/Arnold-Hotels-LGBT-Friendly-Hotel.0-0-d177608-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - 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