Title: Book the Best Heart of Missoula LUXURY Hotels - Upscale Hotels in Heart of Missoula, Missoula | Expedia.ca [Heart of Missoula Travel Guide](https://expedia.ca/Missoula-Heart-Of-Missoula.dx553248635976470878)[Vacation Rentals in Missoula](https://expedia.ca/Missoula-Vacation-Rentals.d180035.Travel-Guide-VacationRentals)[Flights to Missoula](https://expedia.ca/Cheap-Flights-To-Missoula.d180035.Travel-Guide-Flights)[Things to do in Missoula](https://expedia.ca/Things-To-Do-In-Missoula.d180035.Travel-Guide-Activities)[Heart of Missoula Car Rentals](https://expedia.ca/Car-Rentals-In-Heart-Of-Missoula.d553248635976470878.Car-Rental-Guide)[Heart of Missoula Vacations](https://expedia.ca/Heart-Of-Missoula.d553248635976470878.Destination-Travel-Guides) ![Missoula showing an administrative building, heritage architecture and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/61000/61535-Missoula.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Heart of Missoula, Missoula ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Heart of Missoula Luxury Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-15&endDate=2025-10-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-16&endDate=2025-10-17&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Heart of Missoula Luxury Hotels ## Top Heart of Missoula Hotel Reviews ![Comfort Inn University](//images.trvl-media.com/lodging/1000000/50000/41500/41425/e5790b01_y.jpg) ### Comfort Inn University 10/10 Excellent "I really like how all the rooms angle their windows either towards the south- either the river or the hills. The open space and benches riverside are a real plus for downtown Missoula. The hot breakfast was quite decent and had a lot of great options. And as usual, the beds can't be beat. " [](https://expedia.ca/Missoula-Hotels-Comfort-Inn-University.h41425.Hotel-Information) ![Red Lion Inn & Suites Missoula](//images.trvl-media.com/lodging/1000000/10000/3300/3211/ccc74880_y.jpg) ### Red Lion Inn & Suites Missoula 10/10 Excellent "For the price it was great. I wanted a clean bed and a place that was easy. I could park right by my room and getting in and out was easy and quick. " [](https://expedia.ca/Missoula-Hotels-Red-Lion-Inn-Suites-Missoula.h3211.Hotel-Information) ![Days Inn and Suites by Wyndham Downtown Missoula-University](//images.trvl-media.com/lodging/10000000/9830000/9823500/9823477/2b7a4605_y.jpg) ### Days Inn and Suites by Wyndham Downtown Missoula-University 10/10 Excellent "Easy in and out Good location" [](https://expedia.ca/Missoula-Hotels-Campus-Inn-Missoula.h9823477.Hotel-Information) ![DoubleTree by Hilton Hotel Missoula - Edgewater](//images.trvl-media.com/lodging/1000000/30000/25400/25334/7c7afd52_y.jpg) ### DoubleTree by Hilton Hotel Missoula - Edgewater 10/10 Excellent "onsite restaurant is excellent." [](https://expedia.ca/Missoula-Hotels-DoubleTree-By-Hilton-Hotel-Missoula-Edgewater.h25334.Hotel-Information) ![Motel 6-Missoula, MT - University](//images.trvl-media.com/lodging/2000000/1640000/1631400/1631317/2f2f7e8b_y.jpg) ### Motel 6-Missoula, MT - University 10/10 Excellent "The front desk lady was great and very helpful! " [](https://expedia.ca/Missoula-Hotels-Motel-6-Missoula.h1631317.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury getaway to Heart of Missoula? > Use Expedia to arrange your flight to Missoula Intl. Airport (MSO) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Heart of Missoula has to offer. Heart of Missoula has some interesting things to see and do including Wilma Theatre and Clark Fork River, so you might want to take in the local sights during your visit. ### What's there to see and do in Heart of Missoula? > Enjoy Heart of Missoula with a stop at Wilma Theatre, Clark Fork River, and Missoula Art Museum. 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