Title: Book the Best BUSINESS Hotels in Heart of Missoula in 2025 | Expedia.ca [Heart of Missoula Travel Guide](https://expedia.ca/Missoula-Heart-Of-Missoula.dx553248635976470878)[Vacation Rentals in Missoula](https://expedia.ca/Missoula-Vacation-Rentals.d180035.Travel-Guide-VacationRentals)[Flights to Missoula](https://expedia.ca/Cheap-Flights-To-Missoula.d180035.Travel-Guide-Flights)[Things to do in Missoula](https://expedia.ca/Things-To-Do-In-Missoula.d180035.Travel-Guide-Activities)[Heart of Missoula Car Rentals](https://expedia.ca/Car-Rentals-In-Heart-Of-Missoula.d553248635976470878.Car-Rental-Guide)[Heart of Missoula Vacations](https://expedia.ca/Heart-Of-Missoula.d553248635976470878.Destination-Travel-Guides) ![Missoula showing an administrative building, heritage architecture and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/61000/61535-Missoula.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Heart of Missoula, MT from CA $107 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Heart of Missoula Business Hotels Tonight [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-22&endDate=2025-10-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976470878&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Heart of Missoula Business Hotels ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/41500/41425/e5790b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | View from room](https://images.trvl-media.com/lodging/1000000/50000/41500/41425/40673036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/41500/41425/7a4d3747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41500/41425/15a62086.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn University Heart of Missoula 9.0/10 Wonderful (1046) "Very nice stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $149 CA $167 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Missoula-Hotels-Comfort-Inn-University.h41425.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/10000000/9830000/9823500/9823477/2b7a4605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9830000/9823500/9823477/10203fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/10000000/9830000/9823500/9823477/72a14bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/10000000/9830000/9823500/9823477/4739a4b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Downtown Missoula-University Heart of Missoula 7.4/10 Good (1018) "Sandra the manager was wonderful and our room was clean and very comfortable!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kory CA $120 CA $135 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Missoula-Hotels-Campus-Inn-Missoula.h9823477.Hotel-Information) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/64000000/63220000/63217500/63217484/c6cb24a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63220000/63217500/63217484/fbc6187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/64000000/63220000/63217500/63217484/98977902.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/64000000/63220000/63217500/63217484/203db0fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott Missoula Downtown Heart of Missoula 9.0/10 Wonderful (260) "The only complaint I had was the breakfast wasn't as advertised and not worth $16." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Billy CA $233 CA $257 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Missoula-Hotels-AC-Hotel-By-Marriott-Missoula-Downtown.h63217484.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9500/9471/a9542097.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/9500/9471/42e52b3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 5:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/9500/9471/613f6423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Park View](https://images.trvl-media.com/lodging/1000000/10000/9500/9471/a08a2519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Downtown - Missoula by IHG Heart of Missoula 8.4/10 Very good (1008) "Great stay and comfortable rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) marco CA $226 CA $249 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Missoula-Hotels-Holiday-Inn-Downtown-Missoula.h9471.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33300000/33291200/33291172/2e28e98f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/34000000/33300000/33291200/33291172/0bccb565.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33300000/33291200/33291172/09fbc799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, desk, laptop workspace](https://images.trvl-media.com/lodging/34000000/33300000/33291200/33291172/f6b6717f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Missoula Downtown Heart of Missoula 9.4/10 Exceptional (749) "Always pleasant staying here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara CA $208 CA $230 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Missoula-Hotels-Residence-Inn-By-Marriott-Missoula-Downtown.h33291172.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25400/25334/7c7afd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/25400/25334/33f566bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/30000/25400/25334/18690227.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/30000/25400/25334/89ad4144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Hotel Missoula - Edgewater Heart of Missoula 8.8/10 Excellent (1000) "Gorgeous view!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia CA $217 CA $240 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Missoula-Hotels-DoubleTree-By-Hilton-Hotel-Missoula-Edgewater.h25334.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3300/3211/ccc74880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3211/d02aab9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3211/e915b648.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/3300/3211/d84cd17f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Lion Inn & Suites Missoula Heart of Missoula 5.4/10 (1002) "Staff was great when we checked in. The room and property could use some work. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie CA $130 CA $146 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Missoula-Hotels-Red-Lion-Inn-Suites-Missoula.h3211.Hotel-Information) ![Lake](https://images.trvl-media.com/lodging/1000000/10000/5400/5308/86faa164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/10000/5400/5308/f04b8113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/5400/5308/7540d3eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/5400/5308/42db75c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Lolo / Missoula Area Lolo 7.2/10 Good (723) "Busy location, was ok for staying the night. Many dining options accessible by car." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $100 CA $108 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Missoula-Hotels-Days-Inn-By-Wyndham-Lolo-Missoula-Area.h5308.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1030000/1030000/1029909/9191208d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1030000/1030000/1029909/w3836h2561x4y0-932a3650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1030000/1030000/1029909/w3836h2557x4y4-c7a1fefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/2000000/1030000/1030000/1029909/6d7150b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Missoula, MT Grant Creek 8.8/10 Excellent (1371) "Excellent staff and nice room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $93 CA $107 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Missoula-Hotels-Motel-6-Missoula.h1029909.Hotel-Information) ![In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/40000/34500/34430/60cbb3f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34500/34430/37d1719a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34500/34430/4e253927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/34500/34430/7e3e151d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Missoula Airport Grant Creek 9.0/10 Wonderful (1001) "Easy freeway access, clean and spacious rooms, friendly and helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DAVID CA $150 CA $171 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Missoula-Hotels-Comfort-Inn.h34430.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07®ionId=553248635976470878&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Heart of Missoula Hotel Reviews ![DoubleTree by Hilton Hotel Missoula - Edgewater](//images.trvl-media.com/lodging/1000000/30000/25400/25334/7c7afd52_y.jpg) ### DoubleTree by Hilton Hotel Missoula - Edgewater 10/10 Excellent "Nice, clean room. Great staff " [](https://expedia.ca/Missoula-Hotels-DoubleTree-By-Hilton-Hotel-Missoula-Edgewater.h25334.Hotel-Information) ![Comfort Inn University](//images.trvl-media.com/lodging/1000000/50000/41500/41425/e5790b01_y.jpg) ### Comfort Inn University 10/10 Excellent "The location was perfect for our university visit and the balcony view was stunning. It was great to have a sitting area looking toward the water and mountains. Appreciated the large countertop in the bathroom. The front desk service was friendly and helpful. Would definitely stay here again. " [](https://expedia.ca/Missoula-Hotels-Comfort-Inn-University.h41425.Hotel-Information) ![City Center Motel](//images.trvl-media.com/lodging/13000000/12230000/12228100/12228066/76851c9d_y.jpg) ### City Center Motel 10/10 Excellent "Staff at check-in and check-out friendly and professional. I believe they really care about their guests!" [](https://expedia.ca/Missoula-Hotels-City-Center-Motel.h12228066.Hotel-Information) ![Holiday Inn Downtown - Missoula by IHG](//images.trvl-media.com/lodging/1000000/10000/9500/9471/a9542097_y.jpg) ### Holiday Inn Downtown - Missoula by IHG 10/10 Excellent "Property is in a great location. Close to downtown, restaurants and university. Staff was friendly and accommodating. Room was clean and quiet." [](https://expedia.ca/Missoula-Hotels-Holiday-Inn-Downtown-Missoula.h9471.Hotel-Information) ![Red Lion Inn & Suites Missoula](//images.trvl-media.com/lodging/1000000/10000/3300/3211/ccc74880_y.jpg) ### Red Lion Inn & Suites Missoula 10/10 Excellent "For the price it was great. I wanted a clean bed and a place that was easy. I could park right by my room and getting in and out was easy and quick. " [](https://expedia.ca/Missoula-Hotels-Red-Lion-Inn-Suites-Missoula.h3211.Hotel-Information) ![Thunderbird Motel](//images.trvl-media.com/lodging/14000000/13280000/13278900/13278802/2639b4a4_y.jpg) ### Thunderbird Motel 10/10 Excellent "Very friendly staff and in a great location!" 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