Title: Hotels by Best Western in Hartsville | Expedia.ca [Hartsville Travel Guide](https://expedia.ca/Hartsville.dx7762)[Hotels in Hartsville](https://expedia.ca/Hartsville-Hotels.d7762.Travel-Guide-Hotels)[Vacation Rentals in Hartsville](https://expedia.ca/Hartsville-Vacation-Rentals.d7762.Travel-Guide-VacationRentals)[Flights to Hartsville](https://expedia.ca/Cheap-Flights-To-Hartsville.d7762.Travel-Guide-Flights)[Things to do in Hartsville](https://expedia.ca/Things-To-Do-In-Hartsville.d7762.Travel-Guide-Activities)[Hartsville Car Rentals](https://expedia.ca/Car-Rentals-In-Hartsville.d7762.Car-Rental-Guide)[Hartsville Vacation Packages](https://expedia.ca/Hartsville.d7762.Destination-Travel-Guides) ![The Midnight Rooster is my go to spot in my hometown of Hartsville, SC. Great brunch and coffee! Love the courtyard!](https://images.trvl-media.com/place/7762/94f24b5a-6f19-4be1-9683-553b4be73135.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Caroline Nunez # Find Hotels by Best Western in Hartsville - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=7762&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FHartsville-Hotels-Best-Western.0-0-d7762--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FHartsville-Hotels-Best-Western.0-0-d7762--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Hartsville Hotel Reviews ![Fairfield Inn by Marriott Hartsville](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/c0813d21_y.jpg) ### Fairfield Inn by Marriott Hartsville 10/10 Excellent "very friendly older property but clean" [](https://expedia.ca/Florence-Hotels-Fairfield-Inn-By-Marriott-Hartsville.h202854.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "Everything was great. " [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "Plenty of space, but it also had a cozy/comfortable feel. Staff was super friendly and there was a good variety of items available for the free breakfast. Everything was clean, the bed was very comfortable.. Just 5-10 minutes from 95, and plenry of food and shopping options nearby." [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Residence Inn Marriott Florence](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb_y.jpg) ### Residence Inn Marriott Florence 10/10 Excellent "Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day" [](https://expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "I wish Hyatt Place would upgrade the scramble egg on the menu. The powdered eggs are not very good. It's not the staff's fault. I'm sure it is a corporate decision. Step up the breakfast menu." [](https://expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Home2 Suites by Hilton Florence, SC](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409_y.jpg) ### Home2 Suites by Hilton Florence, SC 10/10 Excellent "Very clean room, bed was very comfortable and the room had a great kitchenette. I would defy stay here again. " [](https://expedia.ca/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "The hotel was excellent. In fact we stayed 2 different nights on our travel up and down Rt 95\. Breakfast was great and hotel very clean and quiet. " [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Rooms were spacious and clean. Usual continental breakfast with waffles. " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "My stay was nice My room attendant had me waiting for towels so long I went to get them myself check in person was nice and professional and accommodating I would stay again " [](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Florence ](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Ashland Hotels ](https://www.expedia.ca/Ashland-Hotels.d553248635975868534.Travel-Guide-Hotels) - [Motels in Ashland ](https://www.expedia.ca/Ashland-Motels.d553248635975868534-aaMotels.Travel-Guide-Accommodation) - 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