Title: Book the Best Guadalupe District Adults Only Resorts & Hotels in 2025 from CA $86 | Expedia.ca [Guadalupe District Travel Guide](https://expedia.ca/Santa-Fe-Guadalupe-District.dx553248635976481064)[Vacation Rentals in Santa Fe](https://expedia.ca/Santa-Fe-Vacation-Rentals.d180028.Travel-Guide-VacationRentals)[Flights to Santa Fe](https://expedia.ca/Cheap-Flights-To-Santa-Fe.d180028.Travel-Guide-Flights)[Things to do in Santa Fe](https://expedia.ca/Things-To-Do-In-Santa-Fe.d180028.Travel-Guide-Activities)[Guadalupe District Car Rentals](https://expedia.ca/Car-Rentals-In-Guadalupe-District.d553248635976481064.Car-Rental-Guide)[Guadalupe District Vacations](https://expedia.ca/Guadalupe-District.d553248635976481064.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/f43c118afa88b3b1014949c6b0ffe655.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Rick Tuers # Find Adults Only Resorts & Hotels in Guadalupe District, NM from CA $86 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Guadalupe District Adults Only Resorts & Hotels Tonight [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-20&endDate=2025-10-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Guadalupe District Adults Only Resorts & Hotels We don't have any properties that match your exact search [See all properties in Guadalupe District](https://expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03®ionId=553248635976481064&adults=2) ## Recommended hotels in Guadalupe District ![Porch](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/fcb94873.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Studio (Room 8, Ground Floor) | Private kitchenette](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/eaff103e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room, 1 Queen Bed (Room 10,Upstairs) | Living area](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/3235de96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite (Room 11, Upstairs) | Deep soaking bathtub](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/5c91af71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guadalupe Inn Downtown Santa Fe 9.2/10 Wonderful (1002) "Really good morning burritos for breakfast, plus a variety of other food. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $147 CA $174 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Santa-Fe-Hotels-Guadalupe-Inn.h8806154.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/899025f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, travel crib, WiFi, bed sheets](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/fe5f1ebf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/7a772762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/e2934974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Closson Studio- Stylish | Near Plaza | Queen bed Downtown Santa Fe 9.8/10 Exceptional (19) "Great, clean stay in a great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) robert g. CA $97 CA $236 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Santa-Fe-Hotels-Closson-Studio-Stylish-Near-Plaza-Queen-Bed.h63331963.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/9eccaf6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/6fb3878a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/e366b0d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/b81bfa29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort on Closson- Near Plaza - Fire Pit- Patio Downtown Santa Fe 9.4/10 Exceptional (14) "The property had everything we wanted amenity-wise, was convenient to the places we wanted to go, and the little courtyard was lovely." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim J. CA $83 CA $242 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Santa-Fe-Hotels-Comfort-On-Closson-Near-Plaza-Fire-Pit-Patio.h63331941.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/5e87df09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/2ce1ed5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/637e6f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/3736a301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Complejo de Closson- 4 Casitas- Railyard & Plaza Downtown Santa Fe 10/10 Exceptional (4) "Nice place, great location. Was perfect for 8 old friends for our 11th annual get-together." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse S. CA $254 CA $814 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Santa-Fe-Hotels-Complejo-De-Closson-4-Casitas-Railyard-Plaza.h110948077.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/0c25f042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/737d725f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, travel crib, WiFi, bed sheets](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/3e825703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/03a7e64e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Closson Getaway- Courtyard | Railyard and Plaza Downtown Santa Fe 9.8/10 Exceptional (13) "Great location, walkable to everywhere…Railyard, downtown. Super quiet. Would happily stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jane P. CA $86 CA $230 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Santa-Fe-Hotels-Closson-Getaway-Courtyard-Railyard-And-Plaza.h63331733.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/34e31d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/6820c5d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/bda9d64b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/174ff73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Closson Casita- Patio & Fire Pit |Near Plaza | 1BR Downtown Santa Fe 9.4/10 Exceptional (17) "Closson Casita was clean and comfortable. The home was stocked with everything we needed. The location was perfect. Nestled into a quiet neighborhood just minutes by foot from shopping and galleries. We enjoyed our stay and would rent here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth P. CA $108 CA $275 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Santa-Fe-Hotels-House.h63331952.Hotel-Information) ![Rooftop bar](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/8f424b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/b25df96b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/daa6bd3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/b8625372.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel in Santa Fe Downtown Santa Fe 9.6/10 Exceptional (1358) "Great place! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $191 CA $220 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Santa-Fe-Hotels-Drury-Plaza-Hotel-In-Santa-Fe.h8199136.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/95e1e199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds (Traditional Double Queen Room)](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/8e151f97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/a2c45b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/1ca16805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sage Hotel Don Diego 8.0/10 Very good (1994) "Was a great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenny CA $83 CA $117 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Santa-Fe-Hotels-The-Sage-Hotel.h26295.Hotel-Information) ![Standard Room, 2 Queen Beds (Double Queen Room)](https://images.trvl-media.com/lodging/1000000/860000/855700/855633/890a14a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855700/855633/657d43b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/860000/855700/855633/0f1ebb65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/860000/855700/855633/4d0e629a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coyote South Southside 8.2/10 Very good (2838) "Great place to stay. So friendly, perfect location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynz CA $62 CA $86 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Santa-Fe-Hotels-Coyote-South.h855633.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/915700/915648/7123cfce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/920000/915700/915648/w2877h1407x0y0-0bc018cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/920000/915700/915648/8a4635d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/915700/915648/a7651fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Sendero Inn, an Ascend Collection Hotel Downtown Santa Fe 9.0/10 Wonderful (1497) "Very easy stay! Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie CA $147 CA $170 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Santa-Fe-Hotels-El-Sendero-Inn.h915648.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. 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