Title: Book the Best Guadalupe District Adults Only Resorts & Hotels in 2026 from CA $113 | Expedia.ca [Guadalupe District Travel Guide](https://expedia.ca/Santa-Fe-Guadalupe-District.dx553248635976481064)[Vacation Rentals in Santa Fe](https://expedia.ca/Santa-Fe-Vacation-Rentals.d180028.Travel-Guide-VacationRentals)[Flights to Santa Fe](https://expedia.ca/Cheap-Flights-To-Santa-Fe.d180028.Travel-Guide-Flights)[Things to do in Santa Fe](https://expedia.ca/Things-To-Do-In-Santa-Fe.d180028.Travel-Guide-Activities)[Guadalupe District Car Rentals](https://expedia.ca/Car-Rentals-In-Guadalupe-District.d553248635976481064.Car-Rental-Guide)[Guadalupe District Vacations](https://expedia.ca/Guadalupe-District.d553248635976481064.Destination-Travel-Guides) ![A great evening visiting the art galleries topped with a stop at a brew pub draft in the Santa Fe Railroad Artisan Museum district.](https://images.trvl-media.com/place/180028/cb561ed4-94b9-475c-a214-9227252293c1.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Rick Tuers # Find Adults Only Resorts & Hotels in Guadalupe District, NM from CA $113 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Guadalupe District Adults Only Resorts & Hotels Tonight [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976481064&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) No exact matches found, but these alternatives could be just right ## Recommended hotels in Guadalupe District ![Porch](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/fcb94873.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite (Room 11, Upstairs) | Deep soaking bathtub](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/5c91af71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Studio (Room 8, Ground Floor) | Private kitchenette](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/eaff103e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite (Room 11, Upstairs) | View from room](https://images.trvl-media.com/lodging/9000000/8810000/8806200/8806154/a3fd5df1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guadalupe Inn [](https://www.expedia.ca/Santa-Fe-Hotels-Guadalupe-Inn.h8806154.Hotel-Information) Downtown Santa Fe 9.2/10 Wonderful (1001) "Cozy, quiet, and great for couples!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emerson CA $103 CA $123 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Guadalupe-Inn.h8806154.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/899025f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/7a772762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/e2934974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331963/bd6ae371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Closson Studio- Stylish | Near Plaza | Queen bed [](https://www.expedia.ca/Santa-Fe-Hotels-Closson-Studio-Stylish-Near-Plaza-Queen-Bed.h63331963.Hotel-Information) Downtown Santa Fe 9.8/10 Exceptional (20) "We LOVED our stay here! It was cozy and just what we needed for a night in Santa Fe. It’s a fantastic location! Very nice and communicative hosts. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kara B. CA $81 CA $215 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Santa-Fe-Hotels-Closson-Studio-Stylish-Near-Plaza-Queen-Bed.h63331963.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/0c25f042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/03a7e64e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, travel crib, WiFi, bed sheets](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/3e825703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63331800/63331733/737d725f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Closson Getaway- Courtyard | Railyard and Plaza [](https://www.expedia.ca/Santa-Fe-Hotels-Closson-Getaway-Courtyard-Railyard-And-Plaza.h63331733.Hotel-Information) Downtown Santa Fe 9.8/10 Exceptional (14) "Comfortable, quiet, great location, and decor. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathy S. CA $84 CA $226 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Closson-Getaway-Courtyard-Railyard-And-Plaza.h63331733.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/5e87df09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/637e6f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/3736a301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110950000/110948100/110948077/2ce1ed5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Complejo de Closson- 4 Casitas- Railyard & Plaza [](https://www.expedia.ca/Santa-Fe-Hotels-Complejo-De-Closson-4-Casitas-Railyard-Plaza.h110948077.Hotel-Information) Downtown Santa Fe 10/10 Exceptional (5) "Nice place, great location. Was perfect for 8 old friends for our 11th annual get-together." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse S. CA $240 CA $779 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Santa-Fe-Hotels-Complejo-De-Closson-4-Casitas-Railyard-Plaza.h110948077.Hotel-Information) ![Fridge, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/106000000/105180000/105170400/105170361/ca8599d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/106000000/105180000/105170400/105170361/69dd59ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, stereo](https://images.trvl-media.com/lodging/106000000/105180000/105170400/105170361/2664abf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/106000000/105180000/105170400/105170361/67ec6d1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dream LOCATION - GORGEOUS Adobe - Walk to Everything - Fireplace - King + Queen [](https://www.expedia.ca/Santa-Fe-Hotels-Dream-LOCATION-GORGEOUS-Adobe-Walk-To-Everything-Fireplace-King-Queen.h105170361.Hotel-Information) Downtown Santa Fe 10/10 Exceptional (5) "The Hideaway was a great house for us. The location is perfect, two minutes to the Railyard and an easy walk to downtown. And the neighborhood is so quiet, that was really nice for us and our dogs. The house is a comfortable bohemian style with a great little courtyard. We will definitely go back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anissa J. CA $273 CA $503 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Santa-Fe-Hotels-Dream-LOCATION-GORGEOUS-Adobe-Walk-To-Everything-Fireplace-King-Queen.h105170361.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/9eccaf6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/1d2b3c5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/6fb3878a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331941/b81bfa29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort on Closson- Near Plaza - Fire Pit- Patio [](https://www.expedia.ca/Santa-Fe-Hotels-Comfort-On-Closson-Near-Plaza-Fire-Pit-Patio.h63331941.Hotel-Information) Downtown Santa Fe 9.4/10 Exceptional (14) "The property had everything we wanted amenity-wise, was convenient to the places we wanted to go, and the little courtyard was lovely." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim J. CA $81 CA $238 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Comfort-On-Closson-Near-Plaza-Fire-Pit-Patio.h63331941.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/34e31d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/6820c5d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/174ff73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63340000/63332000/63331952/ffb9c047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Closson Casita- Patio & Fire Pit |Near Plaza | 1BR [](https://www.expedia.ca/Santa-Fe-Hotels-House.h63331952.Hotel-Information) Downtown Santa Fe 9.4/10 Exceptional (17) "Really nice place and excellent location. Next time I travel to Santa Fe I will check if the “Casita” is available." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff B. CA $81 CA $238 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-House.h63331952.Hotel-Information) ![Rooftop bar](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/8f424b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/e8430692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/b25df96b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/9000000/8200000/8199200/8199136/b8625372.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel in Santa Fe [](https://www.expedia.ca/Santa-Fe-Hotels-Drury-Plaza-Hotel-In-Santa-Fe.h8199136.Hotel-Information) Downtown Santa Fe 9.6/10 Exceptional (1422) "The room, cleanliness, breakfast, hospitality, the location and front desk staff - everything was fantastic!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Manju CA $187 CA $216 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Santa-Fe-Hotels-Drury-Plaza-Hotel-In-Santa-Fe.h8199136.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/95e1e199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds (Traditional Double Queen Room)](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/8e151f97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/a2c45b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/26300/26295/1ca16805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sage Hotel [](https://www.expedia.ca/Santa-Fe-Hotels-The-Sage-Hotel.h26295.Hotel-Information) Don Diego 8.0/10 Very good (2121) "Clean room, friendly staff, great restaurant / bar and all at an incredible price!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $81 CA $113 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Santa-Fe-Hotels-The-Sage-Hotel.h26295.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/9700/9603/5e0c5dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/9700/9603/ebccf238.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive lounge](https://images.trvl-media.com/lodging/1000000/10000/9700/9603/4c2a5084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9700/9603/0ee65ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Santa Fe Historic Plaza [](https://www.expedia.ca/Santa-Fe-Hotels-Hilton-Santa-Fe-Historic-Plaza.h9603.Hotel-Information) Downtown Santa Fe 8.2/10 Very good (1007) "Beautifully maintained- incredibly helpful staff and the perfect location to see the historic plaza and more. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $157 CA $181 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Santa-Fe-Hotels-Hilton-Santa-Fe-Historic-Plaza.h9603.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-27&endDate=2025-12-28®ionId=553248635976481064&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Top Guadalupe District Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [4 Star Hotels in Santa Fe ](https://www.expedia.ca/4Star-Santa-Fe-Hotels.s40-0-d180028.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Santa Fe ](https://www.expedia.ca/5Star-Santa-Fe-Hotels.s50-0-d180028.Travel-Guide-Filter-Hotels) - [5 Star Hotels in West Guadaloupe ](https://www.expedia.ca/5Star-West-Guadaloupe-Santa-Fe-Hotels.s50-n896318469184905216-0.Travel-Guide-Filter-Hotels) - [Lake Hotels in Albuquerque ](https://www.expedia.ca/Albuquerque-Hotels-Lake-Hotels.0-0-d602663-tLakeHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Albuquerque ](https://www.expedia.ca/Albuquerque-Hotels-Oceanfront-Hotels.0-0-d602663-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - 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