Title: Book the Best BUSINESS Hotels in Greenville - Spartanburg in 2026 | Expedia.ca [Greenville - Spartanburg Travel Guide](https://expedia.ca/Greenville-Spartanburg.dx6035267)[Hotels in Greenville - Spartanburg](https://expedia.ca/Greenville-Spartanburg-Hotels.d6035267.Travel-Guide-Hotels)[Vacation Rentals in Greenville - Spartanburg](https://expedia.ca/Greenville-Spartanburg-Vacation-Rentals.d6035267.Travel-Guide-VacationRentals)[Flights to Greenville - Spartanburg](https://expedia.ca/Cheap-Flights-To-Greenville-Spartanburg.d6035267.Travel-Guide-Flights)[Things to do in Greenville - Spartanburg](https://expedia.ca/Things-To-Do-In-Greenville-Spartanburg.d6035267.Travel-Guide-Activities)[Greenville - Spartanburg Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville-Spartanburg.d6035267.Car-Rental-Guide)[Greenville - Spartanburg Vacation Packages](https://expedia.ca/Greenville-Spartanburg.d6035267.Destination-Travel-Guides) ![Greenville - Spartanburg which includes a sunset, landscape views and religious aspects](https://images.trvl-media.com/place/6035267/f9a1c090-d6c5-46f5-b727-1be5c766cfdb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina # Find Business Hotels in Greenville - Spartanburg, SC from CA $116 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville - Spartanburg Business Hotels Tonight [Jan 6 - Jan 7](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2026-01-06&endDate=2026-01-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 7 - Jan 8](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6035267&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Greenville - Spartanburg business-friendly hotels ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/e91d409a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ac0c08fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/b54ae3f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville I-385 Inn & Suites [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) Greenville 9.0/10 Wonderful (1432) "Excellent hotel nice and clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irasema CA $105 CA $116 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/f59bfe6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/498d5401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/0007de95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/586dbae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Greenville Woodruff Road [](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) Greenville 9.4/10 Exceptional (1005) "Desk Staff was very kind and helpful. Room was very clean. Overall a wonderful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robin CA $170 CA $187 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/d8b2892f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/3ccb6df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/f5139881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Gaffney by IHG [](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) Gaffney 8.8/10 Excellent (430) "Great people n place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice CA $107 CA $117 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/96a62179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b840578e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Greenville Golf Resort & Conference Center [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) Greenville 9.0/10 Wonderful (1030) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kurt CA $143 CA $157 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 11 per person)](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/159bce9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/0a338dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/b5b2534d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Greenville Downtown [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1009) "Great stay downtown! Close to everything and staff were wonderful! Breakfast had a good variety and was delicious! Will definitely be staying here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Whitney CA $168 CA $185 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/b9f7d424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/c1f887b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/87260578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/c23921a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Greenville Downtown [](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (1005) "Great spot and beautiful hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $172 CA $190 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/267f1593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/62c16e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/9895027f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Greenville Downtown Riverplace [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1010) "We really enjoyed our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frances CA $190 CA $209 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/75c3dac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Corner](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/fd28caf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge, alfresco dining, open daily](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/bd09d7bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/2016aea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott Spartanburg [](https://www.expedia.ca/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) Spartanburg 9.2/10 Wonderful (591) "The gentleman at the front desk when I checked in made me feel very comfortable. He was so chill. It was a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) robert CA $197 CA $219 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/575c54cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/w4000h2665x0y2-7a2b5501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar, tapas bar](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/5385e1d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/cbe0f9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel By Marriott Greenville [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-AC-Hotel-By-Marriott-Greenville.h58282504.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (720) "excellent staff and location. enjoyed our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JONATHAN CA $209 CA $230 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-AC-Hotel-By-Marriott-Greenville.h58282504.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/a1d7ed0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/5e9a8e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/7c5ccfc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown [](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1007) "We will definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosa CA $172 CA $189 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21®ionId=6035267&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Greenville - Spartanburg Hotel Reviews ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "Great location - easy walk to everything in DT Greenville (unless you are spending a lot of time in the West End). The Hotel, Lobby & Room were all clean and accommodating! " [](https://expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Hampton Inn & Suites Greenville-Downtown-RiverPlace](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989_y.jpg) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace 10/10 Excellent "Really nice hotel breakfast and breakfast area is really low but the location you’re walkable to all things downtown. Rooms are nice with balcony. Bring back social hour and update the breakfast and you’ll be on par with Embassy suites next-door." [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88_y.jpg) ### The Westin Poinsett Greenville 10/10 Excellent "Great staff! Wonderful stay!" [](https://expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Yes" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Nice place.." [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Comfort Inn Greenville - Haywood Mall](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/6e5638cc_y.jpg) ### Comfort Inn Greenville - Haywood Mall 10/10 Excellent "Room was really clean and the staff was nice to me " [](https://expedia.ca/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "The room was clean, staffs were welcoming and the breakfast food was good. " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "It was awesome!! All around 10/10" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Great service, good price, staff very friendly" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Greenville - Spartanburg cost? ### What are the best business-friendly hotels in Greenville - Spartanburg? ### How many business-friendly hotels are there in Greenville - Spartanburg? ### What are the best cheap business-friendly hotels in Greenville - Spartanburg? ### What are the top business-friendly motels in Greenville - Spartanburg? ### Are there any family-friendly hotels in Greenville - Spartanburg that are also business friendly? ### Are there any 5-star business-friendly hotels in Greenville - Spartanburg? ### Why book your business-friendly hotel in Greenville - Spartanburg with Expedia? ### How can I find cheap business-friendly hotels in Greenville - Spartanburg? ### What is there to do in Greenville - Spartanburg near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [3 Star Hotels in Greenville ](https://www.expedia.ca/3Star-Greenville-Hotels.s30-0-d1388.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Greenville ](https://www.expedia.ca/5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels) - [Hotels near Bon Secours Wellness Arena ](https://www.expedia.ca/Bon-Secours-Wellness-Arena-Hotels.0-l6082715-0.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Colonel Elias Earle Historic District ](https://www.expedia.ca/Colonel-Elias-Earle-Historic-District-Greenville-Hotels-LGBT-Friendly-Hotel.0-n6348165-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Colonel Elias Earle Historic District ](https://www.expedia.ca/Colonel-Elias-Earle-Historic-District-Greenville-Hotels-Wedding-Hotels.0-n6348165-0-tWeddingHotels.Travel-Guide-Filter-Hotels) - 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