Title: Book the Best Greenville LUXURY Hotels - Upscale Hotels in Greenville, GA | Expedia.ca [Hotels in Greenville](https://expedia.ca/Greenville-Hotels.d6125960.Travel-Guide-Hotels)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d6125960.Travel-Guide-VacationRentals)[Greenville Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville.d6125960.Car-Rental-Guide)[Greenville Vacation Packages](https://expedia.ca/Greenville.d6125960.Destination-Travel-Guides) ![Southern Canody Lined Road with Spanish Moss](https://images.trvl-media.com/place/6125960/976407e3-cd9c-4d7c-8976-3f8980f79d42.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Greenville, GA - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville Luxury Hotels Tonight [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=6125960&startDate=2025-12-26&endDate=2025-12-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6125960&startDate=2025-12-27&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6125960&startDate=2025-12-26&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6125960&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Greenville Hotel Reviews ![Callaway Resort & Gardens](https://images.trvl-media.com/lodging/1000000/40000/37800/37734/abdc1980_y.jpg) ### Callaway Resort & Gardens 10/10 Excellent "room was excellent. Incredibly friendly front desk staff and for that matter, all staff!" [](https://expedia.ca/LaGrange-Hotels-Callaway-Resort-Gardens.h37734.Hotel-Information) ![Motel 6 Lagrange, GA](https://images.trvl-media.com/lodging/1000000/10000/1900/1863/e1f58a34_y.jpg) ### Motel 6 Lagrange, GA 10/10 Excellent "I absolutely needed it the rest and amenities where perfect. Thank you." [](https://expedia.ca/LaGrange-Hotels-Motel-6-Lagrange.h1863.Hotel-Information) ## Frequently asked questions ### Which area of Greenville is best to stay in for luxury hotels? > This area is the heart of Greenville's revitalised city centre, known for its pedestrian-friendly streets and a pleasant blend of historic buildings and modern amenities. Falls Park on the Reedy, with its distinctive Liberty Bridge, is a central landmark, and Main Street is lined with a variety of restaurants, boutiques, and cultural venues. > > > Couples looking for a refined getaway will find downtown Greenville particularly appealing. The concentration of high-end hotels means excellent dining options are often just a short walk away, and evenings can be spent enjoying live music at local venues or taking a leisurely stroll through the park. Many luxury hotels here offer amenities like fine dining restaurants, spas, and high-end fitness equipment. > > > For those on a business trip, downtown offers the convenience of being close to the city's convention centre and various corporate offices. ### How much does a luxury hotel in Greenville cost? ### How can I save on a luxury hotel in Greenville with Expedia? ### Is it cheaper to book a luxury Greenville hotel and flights as a package? ### Can I cancel my luxury hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Adults Only Resorts & in Atlanta ](https://www.expedia.ca/Atlanta-Hotels-Adults-Only-Resorts.0-0-d178232-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Business Hotels in Atlanta ](https://www.expedia.ca/Atlanta-Hotels-Business-Hotel.0-0-d178232-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in Atlanta ](https://www.expedia.ca/Atlanta-Hotels-Green-Sustainable.0-0-d178232-tGreenSustainable.Travel-Guide-Filter-Hotels) - 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