Title: Best Hotels Near Greenville Hospital Systems, Greenville from CA $116 | Expedia.ca [Greenville Travel Guide](https://expedia.ca/Greenville.dx1388)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d1388.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d1388.Travel-Guide-Flights)[Things to do in Greenville](https://expedia.ca/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities)[Greenville Hospital Systems Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville-Hospital-Systems.d624549870530932736.Car-Rental-Guide)[Greenville Hospital Systems Vacations](https://expedia.ca/Greenville-Hospital-Systems-Greenville.d624549870530932736.Vacation-Attraction) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Greenville Hospital Systems, Greenville from CA $116 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=624549870530932736&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=624549870530932736&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=624549870530932736&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=624549870530932736&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Greenville Hospital Systems ![BBQ/picnic area](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/704d2b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/8e2d308e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/b8a8a3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Greenville Downtown West End, 3.3 km from Greenville Hospital Systems 9.6/10 Exceptional (1005) "Room was wonderful and staff very nice." CA $205 CA $231 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/f017a576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/dc5706bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/fbbbf12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/a5be5aef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Greenville near downtown 2.3 km from Greenville Hospital Systems 7.0/10 Good (686) "Near downtown " CA $106 CA $116 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Greenville-Hotels-Quality-Inn-Suites.h41221.Hotel-Information) ![Deluxe Studio, 2 Double Beds](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/6c37dc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, 2 Double Beds](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/cad1b591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 2 Double Beds](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/0c4c1315.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/428a3294.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tanglewood Inn 3.9 km from Greenville Hospital Systems 10/10 Exceptional (6) "We loved our stay! " CA $202 CA $223 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Greenville-Hotels-Tanglewood-Inn.h107962175.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/486bef86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/0a338dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/b5b2534d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Greenville Downtown Greenville Downtown, 4.1 km from Greenville Hospital Systems 9.2/10 Wonderful (1008) "Great staff" CA $190 CA $209 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/0671c5e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/dd539dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown, 3.8 km from Greenville Hospital Systems 9.6/10 Exceptional (389) "Beautiful hotel with views of the Reedy River and Falls. " CA $363 CA $410 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking, River View](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/05a2709e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/1546f0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Balcony](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/c661b163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace Greenville Downtown, 3.9 km from Greenville Hospital Systems 9.4/10 Exceptional (1004) "Always enjoy staying here when we come to Greenville. " CA $211 CA $238 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/cba17315.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/6be9ba14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/48d7212d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/546c8477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swamp Rabbit Inn West End, 3.7 km from Greenville Hospital Systems 9.0/10 Wonderful (350) "Rooms were very clean and had everything I needed. Keypad access was cool and came in handy! Only stayed overnight but would definitely stay again. " CA $162 CA $192 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Greenville-Hotels-Swamp-Rabbit-Inn.h10240653.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/b9f7d424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/87260578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/c1f887b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/c23921a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Greenville Downtown Greenville Downtown, 4.4 km from Greenville Hospital Systems 9.6/10 Exceptional (1002) "Great hotel in a nice walkable area of the city." CA $183 CA $201 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ca99d7c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/e91d409a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ac0c08fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville I-385 Inn & Suites 9.6 km from Greenville Hospital Systems 9.2/10 Wonderful (1361) "It was great Location " CA $131 CA $144 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/267f1593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/62c16e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/9895027f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Greenville Downtown Riverplace Greenville Downtown, 3.9 km from Greenville Hospital Systems 9.2/10 Wonderful (1003) "Very enjoyable location and hospitality. " CA $251 CA $276 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/575c54cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/cbe0f9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/w4000h2665x0y2-7a2b5501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar, tapas bar](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/5385e1d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel By Marriott Greenville Greenville Downtown, 4 km from Greenville Hospital Systems 9.2/10 Wonderful (676) "Perfectly located hotel right on Main St with plenty of walkable dinner options and a great rooftop bar." CA $211 CA $236 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-AC-Hotel-By-Marriott-Greenville.h58282504.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/5698a443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/eb2a711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/3e9b9973.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/b23cade1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pettigru Place Bed & Breakfast Pettigru Street Historic District, 4.8 km from Greenville Hospital Systems 10/10 Exceptional (123) "One of my favorite places to stay in Greenville. It is such a quaint bed and breakfast despite how close it is to downtown. Excellent service and amazing accommodations. " CA $338 CA $371 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Pettigru-Place-Bed-Breakfast.h663745.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/3ff1bced.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds (Large)](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/6145c98b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/8ecfecae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/beafdd29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Greenville South 6.2 km from Greenville Hospital Systems 8.8/10 Excellent (900) "Staff was very friendly " CA $158 CA $175 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Piedmont-Hotels-Comfort-Suites-Greenville-South.h17269961.Hotel-Information) ![Two Bedroom Suite](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a4b477d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/18a2116d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Three Bedroom Suite | Private kitchen](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/6315cb3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a1a743d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville - Downtown West End, 3.8 km from Greenville Hospital Systems 9.2/10 Wonderful (740) "It was very clean and conveniently located. " CA $187 CA $211 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/d892ebd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/8634128c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/878f7da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/38dda9df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Greenville Downtown Greenville Downtown, 4.1 km from Greenville Hospital Systems 9.4/10 Exceptional (1001) "It was very clean and comfortable and we enjoyed this stay very much" CA $189 CA $207 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Courtyard-By-Marriott-Greenville-Downtown.h3374120.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/20000000/19770000/19762800/19762794/86b86435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/20000000/19770000/19762800/19762794/006e2e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19770000/19762800/19762794/cd96a0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/20000000/19770000/19762800/19762794/4c1bfdd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Greenville S- Piedmont by IHG 6 km from Greenville Hospital Systems 9.0/10 Wonderful (477) "Nice place to sleep and relax on my way to NC. Clean, good breakfast, very helpful staff!" CA $177 CA $197 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Piedmont-Hotels-Holiday-Inn-Express-Suites-Greenville-S-Piedmont.h19762794.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/02c3589b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/e5bdee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/a0f70343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Poinsett Greenville Greenville Downtown, 4.2 km from Greenville Hospital Systems 9.2/10 Wonderful (1001) "Very courteous and helpful staff " CA $292 CA $321 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/75fc615c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/6ae45980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/cee4afe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, dishwasher, cookware/dishes/utensils](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/43d7334f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Greenville Downtown Greenville Downtown, 4.9 km from Greenville Hospital Systems 9.2/10 Wonderful (976) "Clean and close to everything Greenville has to offer." CA $212 CA $234 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Greenville-Hotels-Home2-Suites-By-Hilton-Greenville-Downtown.h15217348.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/a2907878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/09f18b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/5757079d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/ff24e798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville South 6 km from Greenville Hospital Systems 8.2/10 Very good (654) "We have stayed here a few times and always are pleased with everything." CA $136 CA $151 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Piedmont-Hotels-Best-Western-Plus-Greenville-South.h2853804.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/a1d7ed0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/01b325b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/7c5ccfc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown Greenville Downtown, 4.5 km from Greenville Hospital Systems 9.0/10 Wonderful (1003) "Great staff great rooms" CA $199 CA $219 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-20&endDate=2025-10-21®ionId=624549870530932736&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGreenville-Hospital-Systems-Hotels.0-l624549870530932736-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGreenville-Hospital-Systems-Hotels.0-l624549870530932736-0.Travel-Guide-Filter-Hotels) ## Top Greenville Hospital Systems Hotel Reviews ![Grand Bohemian Lodge Greenville, Autograph Collection](//images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "What a fabulous hotel. Great location, super clean, and the most helpful staff. " [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "The Hyatt was in the center of eveything that is going on. Staff was very kind and very helpfull and so many good restaurants in walking distance and well night life. Highly recommend staying at the Hyatt Regency!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Hyatt Place Greenville Downtown](//images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "From the moment we arrived until we left the staff was very customer service oriented. Was willing to share and always had a smile!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)](//images.trvl-media.com/lodging/79000000/78630000/78629100/78629037/22eec392_y.jpg) ### Cozy Apt. Near Downtown (2BR, 1BA, 3 beds) 10/10 Excellent "As described. Perfect for our visit. " [](https://expedia.ca/Greenville-Hotels-Cozy-Apt-Near-Downtown.h78629037.Hotel-Information) ![Relax in Style: Gated 2BR in Downtown w/ Workspace](//images.trvl-media.com/lodging/104000000/103170000/103161800/103161791/338346cd_y.jpg) ### Relax in Style: Gated 2BR in Downtown w/ Workspace 10/10 Excellent "We had an excellent stay. The apartment was beautiful and the owner was on top of everything, checking in to make sure we were ok. Would definitely recommend " [](https://expedia.ca/Greenville-Hotels-Spacious-2BR-Apt-In-Gated-Area-Pet-Friendly-Stay.h103161791.Hotel-Information) ![Apt. near Downtown Greenville (2BR/1BA, 3 beds)](//images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/69a716cb_y.jpg) ### Apt. near Downtown Greenville (2BR/1BA, 3 beds) 10/10 Excellent "I've been doing home sharing for the last two years this place on Adger St. is one of the best stays in a while well located to stores & very close to bus routes if traveling with no vehicle quiet area and property is well maintained with all the amenities you need I travel with a service animal and was well received thanks so much" [](https://expedia.ca/Greenville-Hotels-Apt-Near-Downtown-Greenville.h77937495.Hotel-Information) ![Executive home minutes to downtown Greenville, GHS, Swamp Rabbit Trail Sleeps 10](//images.trvl-media.com/lodging/23000000/22510000/22508200/22508104/85991524_y.jpg) ### Executive home minutes to downtown Greenville, GHS, Swamp Rabbit Trail Sleeps 10 10/10 Excellent "Loved the gardens essy access to downtown Greenville. Fresh eggs from the chickens were a bonus!" [](https://expedia.ca/Greenville-Hotels-Executive-Home-Minutes-To-Downtown-Greenville.h22508104.Hotel-Information) ![Family-Friendly 3/2 Home Near Prisma, Fenced Yard](//images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/ae5e5fc7_y.jpg) ### Family-Friendly 3/2 Home Near Prisma, Fenced Yard 10/10 Excellent "We thoroughly enjoyed our stay here. The house was comfortable, well appointed and quiet even though it's in a neighborhood. We will be looking to return next time we're staying in Greenville." [](https://expedia.ca/Greenville-Hotels-Family-Friendly-32-Home-Near-Prisma.h103644605.Hotel-Information) ![Modern Comfort in Gated 2BR Apartment with Parking](//images.trvl-media.com/lodging/107000000/106960000/106955900/106955850/a043fb24_y.jpg) ### Modern Comfort in Gated 2BR Apartment with Parking 10/10 Excellent "Nice place to stay, great communication, well maintained." [](https://expedia.ca/Greenville-Hotels-Modern-2BR-Escape-With-Parking-In-Gated-Community.h106955850.Hotel-Information) ### Hotels near Other Greenville Attractions [](https://expedia.ca/Falls-Park-On-The-Reedy-Hotels.0-l6082697-0.Travel-Guide-Filter-Hotels) ![Falls Park on the Reedy](https://mediaim.expedia.com/destination/1/6bb0f4da89fedda644df8add227a3045.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Falls Park on the Reedy Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082697) [](https://expedia.ca/Shriners-Hospitals-For-Children-Greenville-Hotels.0-l704436698448793600-0.Travel-Guide-Filter-Hotels) #### Shriners Hospitals for Children Greenville Though Shriners Hospitals for Children Greenville might be what brings you to town, perhaps you'll have a chance to explore more of Greenville while you are here. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=704436698448793600) [](https://expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Hotels.0-l553248635941390934-0.Travel-Guide-Filter-Hotels) #### Prisma Health Greenville Memorial Hospital Though Prisma Health Greenville Memorial Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Greenville while you are here. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635941390934) [](https://expedia.ca/Lewis-Plaza-Shopping-Center-Hotels.0-l553248621558035355-0.Travel-Guide-Filter-Hotels) #### Lewis Plaza Shopping Center During your trip to Greenville, you can browse for the perfect souvenirs at Lewis Plaza Shopping Center. Stroll along the riverfront or attend a sporting event in this family-friendly area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558035355) [](https://expedia.ca/Rockwood-Park-Hotels.0-l553248621563220415-0.Travel-Guide-Filter-Hotels) #### Rockwood Park Rockwood Park is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621563220415) [](https://expedia.ca/Augusta-Road-Park-Hotels.0-l553248621532656704-0.Travel-Guide-Filter-Hotels) #### Augusta Road Park Explore the great outdoors at Augusta Road Park, a lovely green space in Greenville. Amble around this family-friendly area's riverfront or attend a sporting event. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532656704)