Title: Book the Best Greater South Side SPA Resorts from CA $260 - Spa Hotels in Greater South Side, Des Moines | Expedia.ca [Vacation Rentals in Des Moines](https://expedia.ca/Des-Moines-Vacation-Rentals.d601690.Travel-Guide-VacationRentals)[Flights to Des Moines](https://expedia.ca/Cheap-Flights-To-Des-Moines.d601690.Travel-Guide-Flights)[Things to do in Des Moines](https://expedia.ca/Things-To-Do-In-Des-Moines.d601690.Travel-Guide-Activities)[Greater South Side Car Rentals](https://expedia.ca/Car-Rentals-In-Greater-South-Side.d553248635976468957.Car-Rental-Guide)[Greater South Side Vacations](https://expedia.ca/Greater-South-Side.d553248635976468957.Destination-Travel-Guides) ![Grays Lake which includes a lake or waterhole](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/268000/268861-Des-Moines.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Greater South Side, Des Moines from CA $260 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greater South Side Spa Hotels Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-10-29&endDate=2025-10-30&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-10-30&endDate=2025-10-31&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Greater South Side Spa Hotels ![Massages](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/99c07eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/a4499f56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/2976bf0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Des Lux Hotel Downtown Des Moines 9.6/10 Exceptional (1042) "Staff was amazing. Great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shailendra CA $232 CA $260 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=553248635976468957&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Greater South Side Hotel Reviews ![Holiday Inn Express & Suites Des Moines Downtown by IHG](//images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7f9d044a_y.jpg) ### Holiday Inn Express & Suites Des Moines Downtown by IHG 10/10 Excellent "Great hotel and excellent staff" [](https://expedia.ca/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) ![Des Lux Hotel](//images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30_y.jpg) ### Des Lux Hotel 10/10 Excellent "We didn't eat breakfast" [](https://expedia.ca/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Holiday Inn Des Moines-Airport/Conf Center by IHG](//images.trvl-media.com/lodging/1000000/20000/18200/18162/7e1d4e9a_y.jpg) ### Holiday Inn Des Moines-Airport/Conf Center by IHG 10/10 Excellent "Clean room. Friendly staff" [](https://expedia.ca/Des-Moines-Hotels-Holiday-Inn-Des-Moines-AirportConf-Center.h18162.Hotel-Information) ![Wildwood Lodge](//images.trvl-media.com/lodging/8000000/7600000/7599000/7598985/c7d37989_y.jpg) ### Wildwood Lodge 10/10 Excellent "Friendly staff, clean rooms" [](https://expedia.ca/Des-Moines-Hotels-Wildwood-Lodge.h7598985.Hotel-Information) ![Stoney Creek Hotel Des Moines - Johnston](//images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/8b967b66_y.jpg) ### Stoney Creek Hotel Des Moines - Johnston 10/10 Excellent "Large cottage. Friendly staff. Very clean" [](https://expedia.ca/Des-Moines-Hotels-Stoney-Creek-Hotel-Des-Moines-Johnston.h1152222.Hotel-Information) ![Quality Inn & Suites Des Moines Airport](//images.trvl-media.com/lodging/1000000/20000/18000/17922/063c0fb4_y.jpg) ### Quality Inn & Suites Des Moines Airport 10/10 Excellent "." [](https://expedia.ca/Des-Moines-Hotels-Quality-Inn-Suites-Des-Moines-Airport.h17922.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Greater South Side? > Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Spa hotels are the perfect way to take a break from your routine and add a layer of luxury to your weekend away. ### What's there to see and do in Greater South Side? > Enjoy all that Greater South Side has to offer when you visit Gray's Lake Park, Lauridsen Amphitheater, and Principal Park. If you have extra time while you're in the area, you might want to stop by Blank Park Zoo and Science Center of Iowa. ### What is a Greater South Side spa hotel? > Spa hotels in Greater South Side feature full on-site spas offering services such as facials and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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