Title: Hotels by La Quinta Inn & Suites in Greater South Side from CA $122 | Expedia.ca [Greater South Side Travel Guide](https://expedia.ca/Des-Moines-Greater-South-Side.dx553248635976468957)[Vacation Rentals in Des Moines](https://expedia.ca/Des-Moines-Vacation-Rentals.d601690.Travel-Guide-VacationRentals)[Flights to Des Moines](https://expedia.ca/Cheap-Flights-To-Des-Moines.d601690.Travel-Guide-Flights)[Things to do in Des Moines](https://expedia.ca/Things-To-Do-In-Des-Moines.d601690.Travel-Guide-Activities)[Greater South Side Car Rentals](https://expedia.ca/Car-Rentals-In-Greater-South-Side.d553248635976468957.Car-Rental-Guide)[Greater South Side Vacations](https://expedia.ca/Greater-South-Side.d553248635976468957.Destination-Travel-Guides) ![Grays Lake which includes a lake or waterhole](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/268000/268861-Des-Moines.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in Greater South Side from CA $122 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-10-15&endDate=2025-10-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-10-16&endDate=2025-10-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976468957&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Greater South Side La Quinta Inn & Suites Hotels ![Indoor pool](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760010/53e01cfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760010/dc8e5938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760010/1f39e752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760010/afcf0559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta by Wyndham Altoona Des Moines Altoona 9.0/10 Wonderful (1569) "Great room and a nice breakfast. " CA $128 CA $143 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Des-Moines-Hotels-La-Quinta-By-Wyndham-Altoona-Des-Moines.h37760010.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278540/351de79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278540/8333844b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278540/63207898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278540/1eea3575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA Ankeny 9.2/10 Wonderful (1010) "Absolutely great staff and place to stay" CA $122 CA $137 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Des-Moines-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ankeny-IA-Des-Moines-IA.h1278540.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/0778119f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/0a0eacfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/7dd58f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/6f522833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Des Moines West Clive Clive 8.6/10 Excellent (1011) "Great service and very clean. " CA $109 CA $122 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Des-Moines-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Des-Moines-West-Clive.h50111.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30®ionId=553248635976468957&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGreater-South-Side-Des-Moines-Hotels-La-Quinta-Inn-Suites.0-n553248635976468957-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGreater-South-Side-Des-Moines-Hotels-La-Quinta-Inn-Suites.0-n553248635976468957-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Greater South Side Hotel Reviews ![Ramada Tropics Resort & Conf Center by Wyndham Des Moines](//images.trvl-media.com/lodging/1000000/10000/1600/1547/b8de3671_y.jpg) ### Ramada Tropics Resort & Conf Center by Wyndham Des Moines 10/10 Excellent "Pool" [](https://expedia.ca/Des-Moines-Hotels-Ramada-Tropics-Resort-Conf-Center-By-Wyndham-Des-Moines.h1547.Hotel-Information) ![Hotel Fort Des Moines, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/9400/9375/9e4e0ef2_y.jpg) ### Hotel Fort Des Moines, Curio Collection by Hilton 10/10 Excellent "Good stuff!" [](https://expedia.ca/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) ![Stoney Creek Hotel Des Moines - Johnston](//images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/8b967b66_y.jpg) ### Stoney Creek Hotel Des Moines - Johnston 10/10 Excellent "Room was clean upon entry and stocked with appropriate items. Staff was friendly and knowledgeable making check in and out easy!" [](https://expedia.ca/Des-Moines-Hotels-Stoney-Creek-Hotel-Des-Moines-Johnston.h1152222.Hotel-Information) ![Motel 6 West Des Moines, IA](//images.trvl-media.com/lodging/1000000/990000/986100/986072/e3428772_y.jpg) ### Motel 6 West Des Moines, IA 10/10 Excellent "The room each huge but it was clean and I got a good sleep there. Worth it for the price. " [](https://expedia.ca/Des-Moines-Hotels-Motel-6-West-Des-Moines.h986072.Hotel-Information) ![Fairfield Inn and Suites by Marriott Des Moines West](//images.trvl-media.com/lodging/1000000/80000/77600/77590/01d93670_y.jpg) ### Fairfield Inn and Suites by Marriott Des Moines West 10/10 Excellent "Room was clean, large and bed was comfortable. I would recommend and stay again. Water pressure was good and 4th floor was quiet. Nice to have restaurants within walking distance." [](https://expedia.ca/Des-Moines-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Des-Moines-West.h77590.Hotel-Information) ![Days Inn & Suites by Wyndham Des Moines Airport](//images.trvl-media.com/lodging/1000000/50000/49900/49826/23994ff1_y.jpg) ### Days Inn & Suites by Wyndham Des Moines Airport 10/10 Excellent "Easy access to airport. Room was spacious and clean" [](https://expedia.ca/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) ![Sonesta Essential Des Moines](//images.trvl-media.com/lodging/1000000/60000/50800/50789/9b65231b_y.jpg) ### Sonesta Essential Des Moines 10/10 Excellent "Clean room, nice amenities and friendly staff" [](https://expedia.ca/Des-Moines-Hotels-Sonesta-Essential-Des-Moines.h50789.Hotel-Information) ![Home2 Suites by Hilton Des Moines at Drake University](//images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e_y.jpg) ### Home2 Suites by Hilton Des Moines at Drake University 10/10 Excellent "Awesome " [](https://expedia.ca/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Des Lux Hotel](//images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30_y.jpg) ### Des Lux Hotel 10/10 Excellent "Great staff! Nice cocktail bar. Cean and spacious room. Would stay again." [](https://expedia.ca/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ## Find out more about Greater South Side ## Greater South Side Hotels Guide Expedia.ca offers a selection of 776 hotels in Greater South Side. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Greater South Side. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Greater South Side neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Greater South Side, Des Moines now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Des Moines](https://www.expedia.ca/5Star-Des-Moines-Hotels.s50-0-d601690.Travel-Guide-Filter-Hotels) - [Hotels near 801 Grand](https://www.expedia.ca/801-Grand-Hotels.0-l6075062-0.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Amana](https://www.expedia.ca/Amana-Hotels-Wyndham-Hotels.0-0-d71429--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Independent Hotels in Aredale](https://www.expedia.ca/Aredale-Hotels-Independent.0-0-d553248634983495074--bIndependent.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Avoca](https://www.expedia.ca/Avoca-Hotels-Wyndham-Hotels.0-0-d183206--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Bondurant](https://www.expedia.ca/Bondurant-Hotels-Red-Roof-Inn.0-0-d553248634983516322--bRedRoofInn.Travel-Guide-Filter-Hotels) - 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[Flights to Iowa](https://www.expedia.ca/Destinations-In-Iowa.d217.Flight-Destinations) - [Flights from Toronto to Des Moines](https://www.expedia.ca/lp/flights/178314/601690/toronto-to-des-moines) - [Flights from Des Moines](https://www.expedia.ca/lp/flights/601690/flights-from-des-moines) - [Flights from Buffalo (BUF) to Des Moines (DSM)](https://www.expedia.ca/lp/flights/buf/dsm/buffalo-to-des-moines) - [Flights from Calgary (YYC) to Des Moines (DSM)](https://www.expedia.ca/lp/flights/yyc/dsm/calgary-to-des-moines) - [Flights from Toronto (YYZ) to Des Moines (DSM)](https://www.expedia.ca/lp/flights/yyz/dsm/toronto-to-des-moines) - [Better Homes and Gardens Test Garden](https://www.expedia.ca/Better-Homes-And-Gardens-Test-Garden-Downtown-Des-Moines.d553248621532649061.Vacation-Attraction) - [Visit Woodland Heights](https://www.expedia.ca/Des-Moines-Woodland-Heights.dx897427645883760640) - [Des Moines Vacations](https://www.expedia.ca/Des-Moines.d601690.Destination-Travel-Guides) - [Visit Des Moines](https://www.expedia.ca/Des-Moines.dx601690) - [Visit Iowa](https://www.expedia.ca/Iowa.dx217) - [John and Mary Pappajohn Sculpture Park](https://www.expedia.ca/John-And-Mary-Pappajohn-Sculpture-Park-Downtown-Des-Moines.d6287745.Vacation-Attraction) - [Principal Park](https://www.expedia.ca/Principal-Park-Downtown-Des-Moines.d6075046.Vacation-Attraction) - [Ruan Center](https://www.expedia.ca/Ruan-Center-Downtown-Des-Moines.d6210743.Vacation-Attraction) - [Car rentals near Des Moines](https://www.expedia.ca/Car-Rentals-In-Des-Moines.d601690.Car-Rental-Guide) - [Des Moines Vacation Rentals](https://www.expedia.ca/Des-Moines-Vacation-Rentals.d601690.Travel-Guide-VacationRentals) - [Book Hotels in Greater South Side on Expedia.com](https://www.expedia.com/Greater-South-Side-Des-Moines-Hotels-La-Quinta-Inn-Suites.0-n553248635976468957-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)