Title: Book the Best Fredericktown LUXURY Hotels - Upscale Hotels in Fredericktown, MO | Expedia.ca [Fredericktown Travel Guide](https://expedia.ca/Fredericktown.dx55114)[Hotels in Fredericktown](https://expedia.ca/Fredericktown-Hotels.d55114.Travel-Guide-Hotels)[Vacation Rentals in Fredericktown](https://expedia.ca/Fredericktown-Vacation-Rentals.d55114.Travel-Guide-VacationRentals)[Flights to Fredericktown](https://expedia.ca/Cheap-Flights-To-Fredericktown.d55114.Travel-Guide-Flights)[Fredericktown Car Rentals](https://expedia.ca/Car-Rentals-In-Fredericktown.d55114.Car-Rental-Guide)[Fredericktown Vacation Packages](https://expedia.ca/Fredericktown.d55114.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/f2491779cf462fb153bab34fde97528f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Summer Williams # Find luxury hotels in Fredericktown, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Fredericktown Luxury Hotels Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=55114&startDate=2025-10-16&endDate=2025-10-17&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=55114&startDate=2025-10-17&endDate=2025-10-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=55114&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=55114&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Fredericktown Luxury Hotels ## Top Fredericktown Hotel Reviews ## Frequently asked questions ### Are you looking for a luxury hotel for your Fredericktown vacation? > Amenities are an important consideration when you plan a vacation, so we make it easy to get what you need to make your stay special. If you want a posh hotel that has fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Fredericktown has to offer. Fredericktown has some interesting things to see and do including Mark Twain National Forest and Silver Mine Recreation Area, so you might want to take in the local sights during your visit. ### When can I expect good weather in Fredericktown? > Planning for the weather is a good way to make your trip to Fredericktown relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Fredericktown is 56 inches. ### What's there to see and do in Fredericktown? > Experience Fredericktown and visit Mark Twain National Forest, Silver Mine Recreation Area, and Millstream Gardens Conservation Area. If you have spare time during your trip, you might want to make a stop at Crown Valley Winery and Pickle Springs Natural Area. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Hotels with Balconies in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Hotels-With-Balconies.0-0-d6282465-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Luxury-Hotel.0-0-d6282465-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Spa-Hotel.0-0-d6282465-tSpaHotel.Travel-Guide-Filter-Hotels) - [Farmstay in Arcadia](https://www.expedia.ca/Arcadia-Agritourism.d6346857-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Arcadia](https://www.expedia.ca/Arcadia-Bed-And-Breakfast.d6346857-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Arcadia](https://www.expedia.ca/Arcadia-Hotels-Cheap-Hotels.0-0-d6346857-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Arcadia](https://www.expedia.ca/Arcadia-Hotels-Luxury-Hotel.0-0-d6346857-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Arcadia Hotels](https://www.expedia.ca/Arcadia-Hotels.d6346857.Travel-Guide-Hotels) - [Lodges in Arcadia](https://www.expedia.ca/Arcadia-Lodges.d6346857-aaLodges.Travel-Guide-Accommodation) - [B&B in Bismarck](https://www.expedia.ca/Bismarck-Bed-And-Breakfast.d553248634983538264-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with a Pool in Bismarck](https://www.expedia.ca/Bismarck-Hotels-Hotel-With-Pool.0-0-d553248634983538264-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Bismarck](https://www.expedia.ca/Bismarck-Hotels-Luxury-Hotel.0-0-d553248634983538264-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Bismarck Hotels](https://www.expedia.ca/Bismarck-Hotels.d553248634983538264.Travel-Guide-Hotels) - [Cheap Hotels in Bonne Terre](https://www.expedia.ca/Bonne-Terre-Hotels-Cheap-Hotels.0-0-d55598-tCheapHotels.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Caledonia](https://www.expedia.ca/Caledonia-Hotels-Cheap-Hotels.0-0-d6359344-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Caledonia](https://www.expedia.ca/Caledonia-Hotels-Golf-Hotel.0-0-d6359344-tGolfHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Caledonia](https://www.expedia.ca/Caledonia-Hotels-Historic-Hotel.0-0-d6359344-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Caledonia](https://www.expedia.ca/Caledonia-Hotels-Wedding-Hotels.0-0-d6359344-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Cottages in Clearwater](https://www.expedia.ca/Clearwater-Cottages.d553248635975868303-aaCottages.Travel-Guide-Accommodation) - [Lodges in Clearwater](https://www.expedia.ca/Clearwater-Lodges.d553248635975868303-aaLodges.Travel-Guide-Accommodation) - [Cobalt Hotels](https://www.expedia.ca/Cobalt-Hotels.d553248634983153223.Travel-Guide-Hotels) - [Cheap Hotels in Des Arc](https://www.expedia.ca/Des-Arc-Hotels-Cheap-Hotels.0-0-d553248634983251690-tCheapHotels.Travel-Guide-Filter-Hotels) - [Desloge Hotels](https://www.expedia.ca/Desloge-Hotels.d55671.Travel-Guide-Hotels) - [Lodges in Desloge](https://www.expedia.ca/Desloge-Lodges.d55671-aaLodges.Travel-Guide-Accommodation) - [Cheap Hotels in Doe Run](https://www.expedia.ca/Doe-Run-Hotels-Cheap-Hotels.0-0-d3000349343-tCheapHotels.Travel-Guide-Filter-Hotels) - [Doe Run Hotels](https://www.expedia.ca/Doe-Run-Hotels.d3000349343.Travel-Guide-Hotels) - [Lodges in Doe Run](https://www.expedia.ca/Doe-Run-Lodges.d3000349343-aaLodges.Travel-Guide-Accommodation) - [Hotels near Elephant Rocks State Park](https://www.expedia.ca/Elephant-Rocks-State-Park-Hotels.0-l553248621532648464-0.Travel-Guide-Filter-Hotels) - [B&B in Farmington](https://www.expedia.ca/Farmington-Bed-And-Breakfast.d6058764-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Farmington](https://www.expedia.ca/Farmington-Cabins.d6058764-aaCabins.Travel-Guide-Accommodation) - [Cheap Hotels in Farmington](https://www.expedia.ca/Farmington-Hotels-Cheap-Hotels.0-0-d6058764-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Farmington](https://www.expedia.ca/Farmington-Hotels-Hotels-With-Hot-Tubs.0-0-d6058764-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Farmington](https://www.expedia.ca/Farmington-Hotels-Pet-Friendly-Hotel.0-0-d6058764-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Farmington Hotels](https://www.expedia.ca/Farmington-Hotels.d6058764.Travel-Guide-Hotels) - [Motels in Farmington](https://www.expedia.ca/Farmington-Motels.d6058764-aaMotels.Travel-Guide-Accommodation) - [Flat River Hotels](https://www.expedia.ca/Flat-River-Hotels.d183474.Travel-Guide-Hotels) - [Glen Allen Hotels](https://www.expedia.ca/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Vacation Homes in Glen Allen](https://www.expedia.ca/Glen-Allen-Private-Vacation-Homes.d553248634983455025-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Farmstay in Iron Mountain Lake](https://www.expedia.ca/Iron-Mountain-Lake-Agritourism.d553248634983534888-aaAgritourism.Travel-Guide-Accommodation) - [Ironton Hotels](https://www.expedia.ca/Ironton-Hotels.d6053585.Travel-Guide-Hotels) - [Lodges in Knob Lick](https://www.expedia.ca/Knob-Lick-Lodges.d553248635975872774-aaLodges.Travel-Guide-Accommodation) - [Leadington Hotels](https://www.expedia.ca/Leadington-Hotels.d553248634983521787.Travel-Guide-Hotels) - [Cheap Hotels in Lesterville](https://www.expedia.ca/Lesterville-Hotels-Cheap-Hotels.0-0-d3000445174-tCheapHotels.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Marble Hill](https://www.expedia.ca/Marble-Hill-Hotels-Cheap-Hotels.0-0-d3000445212-tCheapHotels.Travel-Guide-Filter-Hotels) - [Marble Hill Hotels](https://www.expedia.ca/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [B&B in Middle Brook](https://www.expedia.ca/Middle-Brook-Bed-And-Breakfast.d3000445241-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Middle Brook Hotels](https://www.expedia.ca/Middle-Brook-Hotels.d3000445241.Travel-Guide-Hotels) - [Lodges in Middle Brook](https://www.expedia.ca/Middle-Brook-Lodges.d3000445241-aaLodges.Travel-Guide-Accommodation) - [Aparthotels in Park Hills](https://www.expedia.ca/Park-Hills-Apart-Hotels.d183485-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Park Hills](https://www.expedia.ca/Park-Hills-Bed-And-Breakfast.d183485-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Free Parking in Park Hills](https://www.expedia.ca/Park-Hills-Hotels-Hotels-With-Free-Parking.0-0-d183485-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Park Hills](https://www.expedia.ca/Park-Hills-Hotels-Luxury-Hotel.0-0-d183485-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Park Hills Hotels](https://www.expedia.ca/Park-Hills-Hotels.d183485.Travel-Guide-Hotels) - [Hotels near Perryville Country Club](https://www.expedia.ca/Perryville-Country-Club-Hotels.0-l553248621564822920-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Perryville](https://www.expedia.ca/Perryville-Hotels-Luxury-Hotel.0-0-d6134448-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Perryville Hotels](https://www.expedia.ca/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Rv Parks in Perryville](https://www.expedia.ca/Perryville-RV-Parks.d6134448-aaRVParks.Travel-Guide-Accommodation) - [Hotels with Wifi in Pilot Knob](https://www.expedia.ca/Pilot-Knob-Hotels-Hotel-With-Wifi.0-0-d3000008143-tHotelwithwifi.Travel-Guide-Filter-Hotels) - [Pilot Knob Hotels](https://www.expedia.ca/Pilot-Knob-Hotels.d3000008143.Travel-Guide-Hotels) - [Lodges in Pilot Knob](https://www.expedia.ca/Pilot-Knob-Lodges.d3000008143-aaLodges.Travel-Guide-Accommodation) - [Apartments in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Apartments.d6058763-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Cabins.d6058763-aaCabins.Travel-Guide-Accommodation) - [Castles in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Castles.d6058763-aaCastles.Travel-Guide-Accommodation) - [Drury Inn & Suites Hotels in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Hotels-Drury-Inn-Suites.0-0-d6058763--bDruryInnSuites.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Hotels-La-Quinta-Inn-Suites.0-0-d6058763--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Hotels-Romantic-Hotel.0-0-d6058763-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Hotels-Wedding-Hotels.0-0-d6058763-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Southeast Missouri Hotels](https://www.expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels) - [Lodges in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Lodges.d6058763-aaLodges.Travel-Guide-Accommodation) - [Motels in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-Motels.d6058763-aaMotels.Travel-Guide-Accommodation) - [Rv Parks in Southeast Missouri](https://www.expedia.ca/Southeast-Missouri-RV-Parks.d6058763-aaRVParks.Travel-Guide-Accommodation) - [Cottages in St. Francois County](https://www.expedia.ca/St-Francois-County-Cottages.d553248635083907787-aaCottages.Travel-Guide-Accommodation) - [Honeymoon Resorts and in St. Louis](https://www.expedia.ca/St-Louis-Hotels-Honeymoon-Hotels.0-0-d178309-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Hotels with Childcare in St. Louis](https://www.expedia.ca/St-Louis-Hotels-Hotels-With-Childcare.0-0-d178309-tHotelswithChildcare.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in St. Louis](https://www.expedia.ca/St-Louis-Hotels-Hotels-With-Smoking-Rooms.0-0-d178309-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in St. Louis](https://www.expedia.ca/St-Louis-Hotels-Oceanfront-Hotels.0-0-d178309-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in St. Louis](https://www.expedia.ca/St-Louis-Hotels-Winery-Hotel.0-0-d178309-tWineryHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in St Mary](https://www.expedia.ca/St-Mary-Hotels-Couples-Resorts-Hotels.0-0-d3000445480-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in St Mary](https://www.expedia.ca/St-Mary-Hotels-Golf-Hotel.0-0-d3000445480-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in St Mary](https://www.expedia.ca/St-Mary-Hotels-Hotel-With-Pool.0-0-d3000445480-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in St Mary](https://www.expedia.ca/St-Mary-Hotels-Pet-Friendly-Hotel.0-0-d3000445480-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Ste Genevieve](https://www.expedia.ca/Ste-Genevieve-Hotels-Pet-Friendly-Hotel.0-0-d183502-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Flights to Desloge](https://www.expedia.ca/Cheap-Flights-To-Desloge.d55671.Travel-Guide-Flights) - [Flights to Farmington](https://www.expedia.ca/Cheap-Flights-To-Farmington.d6058764.Travel-Guide-Flights) - [Flights to Ironton](https://www.expedia.ca/Cheap-Flights-To-Ironton.d6053585.Travel-Guide-Flights) - [Flights to Southeast Missouri](https://www.expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights) - [Flights from Dallas to Southeast Missouri](https://www.expedia.ca/lp/flights/178253/6058763/dallas-to-southeast-missouri) - [Flights from Phoenix to Southeast Missouri](https://www.expedia.ca/lp/flights/178298/6058763/phoenix-to-southeast-missouri) - [Flights from Newark to Southeast Missouri](https://www.expedia.ca/lp/flights/601760/6058763/newark-to-southeast-missouri) - [Flights from Southeast Missouri](https://www.expedia.ca/lp/flights/6058763/flights-from-southeast-missouri) - [Flights from Perryville](https://www.expedia.ca/lp/flights/6134448/flights-from-perryville) - [Visit Perryville](https://www.expedia.ca/Perryville.dx6134448) - [Southeast Missouri Vacations](https://www.expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides) - [Visit Southeast Missouri](https://www.expedia.ca/Southeast-Missouri.dx6058763) - [Avis Rental Cars in Farmington](https://www.expedia.ca/Avis-Car-Rentals-In-Farmington.d6058764-c41.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Perryville](https://www.expedia.ca/Budget-Car-Rentals-In-Perryville.d6134448-c39.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Marble Hill](https://www.expedia.ca/Hertz-Car-Rentals-In-Marble-Hill.d3000445212-c40.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Park Hills](https://www.expedia.ca/Hertz-Car-Rentals-In-Park-Hills.d183485-c40.Car-Rental-Guide-Suppliers) - [Marble Hill Vacation Rentals](https://www.expedia.ca/Marble-Hill-Vacation-Rentals.d3000445212.Travel-Guide-VacationRentals) - [Things to do in Southeast Missouri](https://www.expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) - [Book Luxury Hotels in Fredericktown on Expedia.com](https://www.expedia.com/Fredericktown-Hotels-Luxury-Hotel.0-0-d55114-tLuxuryHotel.Travel-Guide-Filter-Hotels)