The hotel was just a few minutes walk from the station and was very easy to find. Although not that far from the, lets say, R rated area, its far enough away to feel quite safe, even for single girls. While the room was on the smallish side, it was of newish appearance. Best request a room at the rear. There is some minor noise if upfront, mainly from passing trams and the occasional street person. Can recommend the coffee/bread shop opposite (on the street with the trams) and also a couple of excellent Chinese restaurants adjacent to the hotel. Only downside was that shower door has a gap, resulting in wet bathroom floor. Also, take care in getting the water temperature right - can easily turn icy cold (or very hot) when trying to turn off the controls.
Would stay again if in Frankfurt