Title: The 10 Best Hotels Near Biomuseo, Panama City from CA $82 | Expedia.ca [Biomuseo Car Rentals](https://expedia.ca/Car-Rentals-In-Biomuseo.d6165383.Car-Rental-Guide)[Biomuseo Vacations](https://expedia.ca/Biomuseo-Amador.d6165383.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 23 - Feb 24](https://www.expedia.ca/Hotel-Search?regionId=6165383&startDate=2026-02-23&endDate=2026-02-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 24 - Feb 25](https://www.expedia.ca/Hotel-Search?regionId=6165383&startDate=2026-02-24&endDate=2026-02-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6165383&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6165383&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Biomuseo hotels ![Interior detail](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/2453d7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (King) | Living area](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6f5654fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (Queen) | Living area](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/f680e3a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Isabela Suites [](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) San Felipe, 2.5 km from Biomuseo 10/10 Exceptional (179 reviews) "Excellent place to stay in the Casco Viejo " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zoe M CA $199 CA $222 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/68c712fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Winery](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/921ce9a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/a8fa0e5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/b8687db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Plaza Herrera [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Herrera.h113477576.Hotel-Information) San Felipe, 2.4 km from Biomuseo 9.8/10 Exceptional (23 reviews) "Hotel Plaza Herrera is a real gem and the staff is all diamonds! We will be back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neal CA $333 CA $368 total includes taxes & fees Mar 6 - Mar 7 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Herrera.h113477576.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/8c9eeca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/34e202d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/5a0a24e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Felipe [](https://www.expedia.ca/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) San Felipe, 2.4 km from Biomuseo 9.4/10 Exceptional (304 reviews) "Great staff and Hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joshua CA $193 CA $213 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/2462f537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Aparta Suite [](https://www.expedia.ca/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador, 1.1 km from Biomuseo 8.4/10 Very good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto CA $94 CA $120 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Room, 1 King Bed, Balcony, Oceanfront (Magnifique)](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/e1979501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/c28c4592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Legend Casco Viejo, Panama City [](https://www.expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) San Felipe, 2.5 km from Biomuseo 9.8/10 Exceptional (598 reviews) "Beautiful place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $529 CA $582 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/fe3d7092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/7b45a441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/dea447f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/ae564df0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal [](https://www.expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) Amador, 1.5 km from Biomuseo 8.6/10 Excellent (1,006 reviews) "Unbeatable location if your visit is all about the Panama Canal. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vitaliy CA $122 CA $134 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3ab6da6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/ba2d7fbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![San Felipe Junior Suite, 1 Double bed or 2 Single Beds](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/4964bad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Corner Suite, 1 King Bed (City View) | Living area](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/a4301523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Concordia Boutique Hotel [](https://www.expedia.ca/Panama-City-Hotels-La-Concordia-Boutique-Hotel.h17380132.Hotel-Information) San Felipe, 2.4 km from Biomuseo 9.6/10 Exceptional (206 reviews) "Great staff. Awesome rooms. The rooftop bar was INCREDIBLE! Highly recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric [](https://www.expedia.ca/Panama-City-Hotels-La-Concordia-Boutique-Hotel.h17380132.Hotel-Information) ![Breakfast, lunch served; local and international cuisine, garden views ](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/c3192737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/89b00dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/32c9362e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/af7444f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### American Trade Hotel [](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) San Felipe, 2.4 km from Biomuseo 9.4/10 Exceptional (662 reviews) "Perfect location with attentive staff and nice rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Negar CA $302 CA $335 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (705) | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana, 2.4 km from Biomuseo 9.0/10 Wonderful (73 reviews) "We live this property and stay here whenever we are in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Apartment (3G) | Living area](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/01dcce3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3K)](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/035f9f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Private kitchen](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/17bc3100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/w2999h2000x0y0-8b973359.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cuadra by Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) El Chorrillo, 2.3 km from Biomuseo 9.0/10 Wonderful (49 reviews) "Superb customer service. Instant responsiveness. Almost miraculous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter CA $135 CA $189 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![47-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![47-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/7a0fd90b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Jetted Tub | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/09deaa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Hotel Panama Casco Viejo [](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) San Felipe, 2.5 km from Biomuseo 9.2/10 Wonderful (1,011 reviews) "Location, amenities and staff were great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orville CA $273 CA $301 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1D)](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/3f9c0f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1C) | Living area](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/7717b8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/04577a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Love by Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) San Felipe, 2.2 km from Biomuseo 8.8/10 Excellent (22 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette CA $119 CA $169 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Apartment, 2 Bedrooms (1A) | Living area](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/42608a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/50831da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Living area](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/fc090f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1A) | Living area](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/0447e43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Lefevre By Wynwood House [](https://www.expedia.ca/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) San Felipe, 2.6 km from Biomuseo 9.2/10 Wonderful (7 reviews) "Staff was courteous, and the room was very beautiful. Would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Selam CA $193 CA $250 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) ![Superior Suite Duplex, Balcony, Sea View](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/83c9df4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite Duplex, Balcony, Sea View | Living area](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/9b59eaff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/1dd7c6ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/14d9a23b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bardot Boutique [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Bardot-Boutique.h119739302.Hotel-Information) San Felipe, 2.5 km from Biomuseo 9.0/10 Wonderful (10 reviews) "What a special place! Very reasonable rate for an amazing location. 2 level suite was sweet! Love the decor. The staff and restuarant/bar is magnificent in every way!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicholas CA $221 CA $243 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Bardot-Boutique.h119739302.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/60cd745e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/5b8b9c6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/bdcbfd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/3eabd2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magnolia Inn [](https://www.expedia.ca/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) San Felipe, 2.5 km from Biomuseo 8.8/10 Excellent (451 reviews) "The room was great and the staff very helpful. Will definitely stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $134 CA $147 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) ![Apartment (1D) | Living area](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/569ccb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/1cdad385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3D) | Private kitchen](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/bf9924b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) San Felipe, 2.2 km from Biomuseo 8.6/10 Excellent (23 reviews) "Great location. At the border of renovated areas but an extremely go deal for this great property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $107 CA $156 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/c1c9d6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Geo Orga by Mariery Young](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/4fafb76c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Fusion cuisine ](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/255ee499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/fab1c02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tantalo Hotel [](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) San Felipe, 2.5 km from Biomuseo 8.8/10 Excellent (286 reviews) "Amazing room, very spacious with a nice balcony, super clean, AC worked perfect, 10/10 everything. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Anupam [](https://www.expedia.ca/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/110000000/109320000/109315700/109315700/40499b9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109320000/109315700/109315700/b439a489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room, Balcony, City View | Balcony](https://images.trvl-media.com/lodging/110000000/109320000/109315700/109315700/4bb52051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Triple Room, City View | Bathroom](https://images.trvl-media.com/lodging/110000000/109320000/109315700/109315700/fe0d6493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Corcho [](https://www.expedia.ca/Panama-City-Hotels-Corcho.h109315700.Hotel-Information) San Felipe, 2.5 km from Biomuseo 8.6/10 Excellent (28 reviews) "Was very clean and walking distance to the most turistic places in the old town" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Hazel CA $161 CA $178 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Panama-City-Hotels-Corcho.h109315700.Hotel-Information) ![Daily cooked-to-order breakfast (USD 5 per person)](https://images.trvl-media.com/lodging/4000000/3770000/3763100/3763066/da5beb8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/4000000/3770000/3763100/3763066/df022bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3770000/3763100/3763066/0d82ee73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3770000/3763100/3763066/1fd2e3b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Balboa Inn [](https://www.expedia.ca/Panama-City-Hotels-The-Balboa-Inn.h3763066.Hotel-Information) Balboa, 2.7 km from Biomuseo 8.8/10 Excellent (129 reviews) "Wonderful staff. Thank you." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JOHN CA $73 CA $82 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Panama-City-Hotels-The-Balboa-Inn.h3763066.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/39ceae17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/6b4a6a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/220ca1b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/18177d00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panama Canal Inn [](https://www.expedia.ca/Panama-City-Hotels-Canal-Inn-BB-Panama.h16111406.Hotel-Information) 2.4 km from Biomuseo 8.4/10 Very good (18 reviews) "Excellent hotel, good location, nice stay and great service." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rocio Hernandez [](https://www.expedia.ca/Panama-City-Hotels-Canal-Inn-BB-Panama.h16111406.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-09&endDate=2026-03-10®ionId=6165383&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Biomuseo | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | -------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Interior detail](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/2453d7ad.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Isabela Suites | 3.5 star property | 10.0Exceptional179 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/68c712fa.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Plaza Herrera | 4.0 star property | 9.8Exceptional23 reviews | View | | | | | | | ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel San Felipe | 4.0 star property | 9.4Exceptional304 reviews | View | | | | | | | ![Comfort Suite, 1 Queen Bed with Sofa bed](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Palma Aparta Suite | 3.0 star property | 8.4Very good7 reviews | View | | | | | | | ![Room, 1 King Bed, Balcony, Oceanfront (Magnifique)](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Sofitel Legend Casco Viejo, Panama City | 5.0 star property | 9.8Exceptional598 reviews | View | | | | | | ## Top Biomuseo Hotel Reviews ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Localização excelente, com ótimo café da manhã." [](https://expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Good" [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Sofitel Legend Casco Viejo, Panama City ](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/fae422a9_y.jpg) ### Sofitel Legend Casco Viejo, Panama City 10/10 Excellent "The hotel was gorgeous - timeless, classy and well appointed. The only disappointment was at the speak easy where I ordered a cocktail and was brought a Taro card. As a Christ follower - it was offensive to me. I asked the waiter to take it back. " [](https://expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) ![Hotel Plaza Herrera](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/26942dc3_y.jpg) ### Hotel Plaza Herrera 10/10 Excellent "What a property!!! If you're looking for flawless accommodations in the Casco Viejo area of Panama City, Hotel Plaza Herrera is it! The attention to detail in its design, the spacious rooms, luxury and spectacular hotel restaurant simply astounded me! Staff are absolutely lovely. The only problem some might have is the fact the property doesn't have an elevator but it's only three stories (staff deliver your luggage to your room) so only those with serious mobility issues might think twice. Location is near everything! I stayed here before a cruise from Colon and an Uber was only about $70 for the 1 hour and 10 minute ride to the terminal. Oh! And you have to check out the restaurant's bathroom floor and sinks: copper US pennies!! Even the door hinges are brass fixtures featuring the hotel logo--as I said, attention to detail! Amazing!" [](https://expedia.ca/Panama-City-Hotels-Hotel-Herrera.h113477576.Hotel-Information) ![Casco View Apartments](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce_y.jpg) ### Casco View Apartments 10/10 Excellent "Everything was perfect " [](https://expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![La Palma Aparta Suite](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/71d83e61_y.jpg) ### La Palma Aparta Suite 10/10 Excellent "Me encantó muy organizado, muy limpio, las personas que trabajan en este hotel son muy amables volvería sin duda muchas gracias " [](https://expedia.ca/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![American Trade Hotel](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/19e6fda8_y.jpg) ### American Trade Hotel 10/10 Excellent "Hotel muy céntrico y bien cuidado, con vistas increíbles a la plaza y las iglesias. El servicio es muy cordial y acogedor. " [](https://expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) ![Hotel Casa Panamá](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/6488c648_y.jpg) ### Hotel Casa Panamá 10/10 Excellent "Great rooms and location was perfect!. Right at the beginning of casco viejo so you can walk right into all the restaurants and easy enough to get an uber to go to any trips outside. Highly recommend!" [](https://expedia.ca/Panama-City-Hotels-Hotel-Casa-Panama.h12091977.Hotel-Information) ![Radisson Hotel Panama Canal](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44_y.jpg) ### Radisson Hotel Panama Canal 10/10 Excellent "Excellent " [](https://expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ## Hotels near other Biomuseo attractions ### Amador Causeway 4.4/5 (1,305 reviews) You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286127) ### Amador Convention Center 4.4/5 (7 reviews) Learn about the events happening at Amador Convention Center during your trip to Ancon. While in this walkable area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976809818) ### Marine Exhibition Center Smithsonian Institute Panama Enjoy an outing to Marine Exhibition Center Smithsonian Institute Panama during your stay in Ancon. Stroll along the seaside in this culturally rich area, or check out its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6159871) ### Maracana Stadium Catch an event at Maracana Stadium during your trip to Panama City. Check out the shops and top-notch restaurants in this culturally rich area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621562725885) ### Smithsonian Tropical Research Institute Punta Culebra 4.8/5 (5 reviews) You can spend time browsing the exhibits at Smithsonian Tropical Research Institute Punta Culebra in Ancon. Amble around this vibrant area's seaside and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6165285) ### Danilo Perez Foundation Explore the campus of Danilo Perez Foundation as part of your travels around Panama City. Check out the shops and top-notch restaurants in this vibrant area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532965258) ### Plaza de Francia You can learn about the history of Panama City when you stop by Plaza de Francia. Check out the shops and top-notch restaurants in this vibrant area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532965269) ### Mola Museum You can spend time browsing the exhibits at Mola Museum during your trip to Panama City. You can enjoy the bars while in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=721481164880883712) ## Frequently asked questions ### What's the area like around Biomuseo? ### What's the best hotel to stay near Biomuseo? ### How many hotels will I be able to find near Biomuseo? ### If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund? ### What can I see and do near Biomuseo?