Title: Book the Best BUSINESS Hotels in Fort Myers River District in 2025 | Expedia.ca [Vacation Rentals in Fort Myers](https://expedia.ca/Fort-Myers-Vacation-Rentals.d602729.Travel-Guide-VacationRentals)[Flights to Fort Myers](https://expedia.ca/Cheap-Flights-To-Fort-Myers.d602729.Travel-Guide-Flights)[Things to do in Fort Myers](https://expedia.ca/Things-To-Do-In-Fort-Myers.d602729.Travel-Guide-Activities)[Fort Myers River District Car Rentals](https://expedia.ca/Car-Rentals-In-Fort-Myers-River-District.d6296330.Car-Rental-Guide)[Fort Myers River District Vacations](https://expedia.ca/Fort-Myers-River-District.d6296330.Destination-Travel-Guides) ![Florida Repertory Theater](https://images.trvl-media.com/place/6296330/bdea2cf6-6941-4ecb-bb61-a136ad5c4327.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Fort Myers River District, FL from CA $102 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Fort Myers River District Business Hotels Tonight [Nov 20 - Nov 21](https://www.expedia.ca/Hotel-Search?regionId=6296330&startDate=2025-11-20&endDate=2025-11-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Nov 21 - Nov 22](https://www.expedia.ca/Hotel-Search?regionId=6296330&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6296330&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6296330&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Fort Myers River District Business Hotels ![Reception](https://images.trvl-media.com/lodging/46000000/45780000/45771200/45771139/e8cb9b69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/46000000/45780000/45771200/45771139/a04607ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/46000000/45780000/45771200/45771139/w2662h4000x0y0-ec3a78ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/46000000/45780000/45771200/45771139/7eb322e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luminary Hotel & Co., Autograph Collection Downtown Historic District 9.2/10 Wonderful (470) "Nice place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $239 CA $267 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Luminary-Hotel-Co.h45771139.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/d99aa2c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/w5751h3835x5y5-83f86631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/w5757h3835x0y5-6dc8e67a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/w5749h3840x5y0-525deb5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Banyan Hotel Fort Myers, Tapestry Collection by Hilton Downtown Historic District 8.6/10 Excellent (832) "Staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $206 CA $229 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Banyan-Hotel-Fort-Myers.h1916874.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95380000/95374500/95374467/w5757h3835x0y5-c3d31148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95380000/95374500/95374467/w5757h3835x0y5-ac9f6ebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/96000000/95380000/95374500/95374467/42c1a856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/96000000/95380000/95374500/95374467/f9f6eba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Fort Myers Downtown Fort Myers River District 9.2/10 Wonderful (797) "Awesome stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darren CA $178 CA $198 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Fort-Myers-Hotels-Hampton-Inn-Fort-Myers-Downtown.h95374467.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/118000000/117840000/117833700/117833624/86707d43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/118000000/117840000/117833700/117833624/61517481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117840000/117833700/117833624/b258534c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117840000/117833700/117833624/8224a66f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gather friends and family in this historical home. Fort Myers River District 8.0/10 Very good (2) "Good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis L. CA $379 CA $694 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Fort-Myers-Hotels-Gather-Friends-And-Family-In-This-Historical-Home.h117833624.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/fe3aa003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/088bfb58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/9ecc1017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG Fort Myers Beach 9.4/10 Exceptional (1009) "Excellent room and price! Breakfast was great. Holiday Inn Express is doing everything right for a comfortable stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $111 CA $124 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/16c0566c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/1fa522a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/953f373d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/a4826c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park Daniels Corridor 8.0/10 Very good (1484) "Clean, comfortable and quiet facility… I would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $92 CA $102 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) ![Standard 2 Queens Non Smoking](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009533/fe46b2a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009533/9a663741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009533/582f23ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009533/d3c93458.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Lehigh Acres Fort Myers Lehigh Acres 8.2/10 Very good (1223) "Good place to rest " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Claudia CA $99 CA $111 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Fort-Myers-Hotels-Quality-Inn-Suites-Lehigh-Acres-Fort-Myers.h2009533.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/2deb021c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/b9d6a513.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/0893d88f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/eec3b567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Fort Myers Airport Daniels Corridor 8.6/10 Excellent (1115) "Staff very accommodating and pleasant. Breakfast was good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela CA $120 CA $134 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Fort-Myers-Hotels-Comfort-Inn-Suites-Airport.h1746276.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/3f55519b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/0fdbdc99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/90cc54bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/w5616h3741x0y0-fd66ddcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Fort Myers/at The Forum The Forum 8.2/10 Very good (1006) "Goodlocation" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Michael CA $142 CA $158 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Hyatt-Place-Fort-Myersat-The-Forum.h2847745.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/cebf36b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Microwave](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/55b8bfc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/d9380a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/5f870412.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Fort Myers Inn & Suites Fort Myers 8.8/10 Excellent (1078) "Service was great, cleanliness was good ad well, really enjoyed breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina CA $102 CA $114 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Best-Western-Fort-Myers-Inn-Suites.h17131.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-04&endDate=2025-12-05®ionId=6296330&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Fort Myers River District Hotel Reviews ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "All of the staff we all top tier! The resort has several activities for adults and kids to partake in, dinning options were great also. " [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "Clean rooms " [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![The Lighthouse Resort Inn & Suites](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "Room was clean but in the older section. Looking forward to a remodel or allowing pets into the new part. Love staying at the Lighthouse and visit regularly " [](https://expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Courtesy & cleanliness " [](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Marriott Sanibel Harbour Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg) ### Marriott Sanibel Harbour Resort & Spa 10/10 Excellent "Staff was very friendly. Nelson went out of the way to help me" [](https://expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Hilton Garden Inn Ft Myers](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a_y.jpg) ### Hilton Garden Inn Ft Myers 10/10 Excellent "Clean room, great front desk staff, good breakfast offerings. We would definately stay there again!" [](https://expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![The Westin Cape Coral Resort At Marina Village](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e_y.jpg) ### The Westin Cape Coral Resort At Marina Village 10/10 Excellent "View was incredible " [](https://expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "Perfect beach, while suppling chairs and umbrellas. Pool and beach bar/food was great. Music was terrific!" [](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Great place . . . please don’t visit next May ! " [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Fort Myers River District cost? > Rates for business hotels in Fort Myers River District range between CA $102 and CA $694 per night. Whatever your budget, Expedia is here to help you find the right place to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### How many business-friendly hotels are there in Fort Myers River District? > Pick from 2 business-friendly hotels in Fort Myers River District. Wherever your next work trip takes you, Expedia makes it a breeze to find the ideal space with the amenities you're looking for. ### Why book your business-friendly hotel in Fort Myers River District with Expedia? > With handy amenities like room service, conference rooms and on-site restaurants, our business-friendly properties come with everything you'll need to close your important deal — and then relax in the comfort of your room. Enter your travel destination and preferred dates and Expedia will help you organize the rest. ### How can I find cheap business-friendly hotels in Fort Myers River District? > When work takes you to Fort Myers River District, our "business friendly" filter will help you find a suitable hotel. From free WiFi to conference spaces and in-room desks, they come with the amenities you need to get down to business. 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