Title: Book the Best BOUTIQUE Hotels in Florence in 2025 | Expedia.ca [Hotels in Florence](https://expedia.ca/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.ca/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Florence Car Rentals](https://expedia.ca/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.ca/Florence.d1221.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/bb3e92b3001d46f023d4e565fc1d1eae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Boutique Hotels in Florence, SC from CA $195 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Florence Boutique Hotels Tonight [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-09-25&endDate=2025-09-26&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-09-26&endDate=2025-09-27&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-09-26&endDate=2025-09-28&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Florence Boutique Hotels ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/9a944163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/5b020e41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms (Penthouse)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/20c926f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Florence, Tapestry Collection by Hilton Florence 8.8/10 Excellent (583) "Very unique property. Great room and bath. No closet but didn’t miss it. It had a hanging trolley. Vicytors restaurant is superb. Staff is more than gracious. " CA $182 CA $204 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/8f02222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/bf604151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/60008f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads Lake City 9.4/10 Exceptional (777) "Fantastic restaurant on site, clean rooms and friendly staff. Very nice hotel." CA $174 CA $195 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/39339da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/acb68e54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Regal mid-King Suite | Private kitchen](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/ff7460f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Private kitchen](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/83bdb053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mantissa Hotel Hartsville 9.2/10 Wonderful (261) "Excellent stay" CA $214 CA $240 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Florence-Hotels-The-Mantissa-Hotel.h15719033.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=1221&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Florence Hotel Reviews ## Frequently asked questions ### What's there to see and do in Florence? > The shopping and restaurants are just some of the things to enjoy while you're in the area. Florence Museum, Florence National Cemetery, and Magnolia Mall are some of the local sights worth visiting. While you're here, you might also like to explore more of the area and take in additional sights like Florence Veterans Park, Florence Civic Center, and Palmetto Shores Lake. ### What kind of weather should I plan for when I travel to Florence? > Having a good idea of the weather in Florence will help you enjoy your stay to the fullest. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches. ### What's the best way to get to my boutique hotel in Florence? > You have a few options for getting to Florence. The nearest major airport is Florence, SC (FLO-Florence Regional), which is located 2.3 mi (3.7 km) from the heart of the city. 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