Title: Book the Best BOUTIQUE Hotels in Florence in 2025 | Expedia.ca [Hotels in Florence](https://expedia.ca/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.ca/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Florence Car Rentals](https://expedia.ca/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.ca/Florence.d1221.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/bb3e92b3001d46f023d4e565fc1d1eae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Boutique Hotels in Florence, SC from CA $107 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Florence Boutique Hotels Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-10-16&endDate=2025-10-17&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-10-17&endDate=2025-10-18&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=1221&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Florence Boutique Hotels We don't have any properties that match your exact search [See all properties in Florence](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=1221&adults=2) ## Recommended hotels in Florence ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2544034c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/0cae09f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/744aa109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible (Comm, Mobility, Access Tub)](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/0392e6eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Latta by IHG Latta 9.4/10 Exceptional (515) "I enjoyed everything about my stay, it was quite peaceful and relaxing. The staff was very nice and the breakfast was good and convenient." CA $145 CA $158 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/51d8f371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC Florence 9.0/10 Wonderful (2156) "We only stayed one night, but honestly our stay as very comfortable, and staff very nice, and welcoming. " CA $133 CA $149 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/ebea43b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/b5687a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence Florence 8.8/10 Excellent (2397) "Great stay" CA $96 CA $107 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/c7afe694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/83187168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/22e67acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence 9.2/10 Wonderful (1110) "The check in clerk was wonderful to deal with!" CA $150 CA $168 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/4c689938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/527e1e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG Florence 9.2/10 Wonderful (1005) "Easy drive right off the interstate. Good dining options nearby." CA $156 CA $175 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/16ca8b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/22eb9cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 Florence 9.0/10 Wonderful (750) "Enjoyed our stay" CA $149 CA $166 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/cbc9a37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/bee831df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown Florence 8.8/10 Excellent (1009) "Bar well stocked, friendly staff, and clean accommodations" CA $163 CA $182 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/94573105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/bdf580c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/37f52847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG Florence 8.6/10 Excellent (1006) "Great accommodations. Staff was very friendly. Breakfast was hot and delicious." CA $162 CA $181 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/c0813d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/bbb1ae5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/82d1dc7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/f91ba6cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Hartsville Hartsville 8.6/10 Excellent (663) "Walking distance to restaurants and bar, quiet area, comfortable beds" CA $131 CA $147 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-By-Marriott-Hartsville.h202854.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/bccde616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 Florence 8.2/10 Very good (1005) "Great clean place to stay!" CA $131 CA $152 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=1221&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Florence Hotel Reviews ## Frequently asked questions ### What's there to see and do in Florence? > The shopping and restaurants are just some of the things to enjoy while you're in the area. Florence Museum, Florence National Cemetery, and Magnolia Mall are some of the local sights worth visiting. While you're here, you might also like to explore more of the area and take in additional sights like Florence Veterans Park, Florence Civic Center, and Palmetto Shores Lake. ### What kind of weather should I plan for when I travel to Florence? > Having a good idea of the weather in Florence will help you enjoy your stay to the fullest. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches. ### What's the best way to get to my boutique hotel in Florence? > You have a few options for getting to Florence. The nearest major airport is Florence, SC (FLO-Florence Regional), which is located 2.3 mi (3.7 km) from the heart of the city. 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