Find hotels near Edisto Island Serpentarium, Edisto Island from CA $539
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
Oct 18 - Oct 19Tomorrow
Oct 19 - Oct 20Next weekend
Oct 23 - Oct 25In two weeks
Oct 30 - Nov 1 Our top choices for Edisto Island Serpentarium hotels
1. The Sanctuary at Kiawah Island Golf Resort
The Sanctuary at Kiawah Island Golf Resort18.2 km from Edisto Island Serpentarium
Jennifer
CA $477
CA $539 total
includes taxes & fees
Nov 8 - Nov 9
2. The Dunlin, Auberge Collection
The Dunlin, Auberge Collection16.4 km from Edisto Island Serpentarium
lauren
CA $650
CA $808 total
includes taxes & fees
Nov 11 - Nov 12
3. Charleston Kiawah Island/Andell Inn
Charleston Kiawah Island/Andell Inn13.4 km from Edisto Island Serpentarium
Kurt
CA $536
CA $630 total
includes taxes & fees
Nov 15 - Nov 16
4. Hideout at Shipwatch - On The Beach
Hideout at Shipwatch - On The Beach15.3 km from Edisto Island Serpentarium
CA $141
CA $580 total
includes taxes & fees
Nov 3 - Nov 4
Top Edisto Island Serpentarium Hotel Reviews
Water Front Edisto with Private Dock On Deep Creek overlooking the Ocean
10/10 Excellent
"Enjoyed our stay. We had a wonderful time. The marsh was beautiful, every time of day. The change was awesome. It was a wonderful place to celebrate our 50th wedding anniversary. There was plenty of room for our children and grandchildren to help us cook, eat, laugh and enjoy."
Ocean Front Home with Breath Taking Views!
10/10 Excellent
"Great location right on the ocean. The house flowed well with plenty of space for our group to eat, play games, talk, and hang out together. Super clean home with comfy beds and 2 great porches to watch for dolphins from. Would definitely return!"
Oceanfront Showplace - Island Manor
10/10 Excellent
"This is our second visit to Island Manor, they have made some great changes since our first time 3 years ago. Dean & Beth are available to their renters for any questions or concerns. Definitely want to come back again!! Just a little warning, the king bedroom on the main floor is awesome, bed very comfy but my sister and I are on the older and shorter side and had many giggles trying to get into bed, finally got a small step stool at ace hardware, worked perfectly "
Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi
10/10 Excellent
"We have been renting pet friendly beach properties for years and finally found a place we want to rent again. This house had everything you could imagine and more. The views of the ocean and the marsh were incredible. Access to the beach was only a short walk and there were so few people it felt like you had the beach to yourself. The entire house was very clean and the hosts were very gracious and accommodating. We definitely plan to rent this home again."
Luxury 5BR Oceanview ~ Chiltren By the Sea
10/10 Excellent
"Very nice property! We and our dogs all had a lovely time."
Newly renovated beachfront house w/Patio, Free WiFi, Private W/D, AC
10/10 Excellent
"Great place to relax! House is perfect location on the beach. Special thanks to our contact Mary."
Moon Tide|Oceanfront Showplace|Dog Friendly|Elevator|Rooftop Deck|Family-Friendly Amenities
10/10 Excellent
"2nd year staying at Moon Tides. Looking forward to our next trip"
Sea Sea Rider
10/10 Excellent
"Everything went very smooth from check in to check out. The condo is in a great location, walking distance from the beach and several restaurants. We’ll be back!"
Partial OCEAN VIEW! Fenced yard bring doggo. WaterFront DOCK Fishing
10/10 Excellent
"We have been coming to Edisto Beach for four years and have stay here every time. The location is great! Half a block to the beach, no traffic, and the dog's area. You can also get up in the morning with your cup of coffee and go sit on the dock and watch the day come to life. Or fish and drink your coffee is wonderful!In the evening you can sit on the back porch and watch the Egrets and King Fishers hunt for their dinner. Rachel is a great host and it was all set when we came in.Thanks!"
Other attractions near Edisto Island Serpentarium
Botany Bay Plantation
8.8/10 (25 reviews)
Explore the great outdoors at Botany Bay Plantation, a lovely green space in Edisto Island. Stroll along the beaches in this relaxing area, or seek out the fishing spots.
With These Hands Gallery
8.0/10 (5 reviews)
You can spend time browsing the exhibits at With These Hands Gallery during your travels in Edisto Island. Stroll along the beautiful beaches in this relaxing area, or seek out the biking trails.
Botany Bay Plantation Heritage Preserve and Wildlife Management Area
9.2/10 (13 reviews)
Explore the lovely green spaces of Botany Bay Plantation Heritage Preserve and Wildlife Management Area and enjoy the biking trails in Edisto Island. Wander the beautiful beaches in this relaxing area.
Edisto Island Museum
8.4/10 (6 reviews)
You can spend time studying the exhibits at Edisto Island Museum during your travels in Edisto Island. Wander the beautiful beaches in this relaxing area.
Edisto Beach State Park
9.0/10 (75 reviews)
You can take time to visit Edisto Beach State Park during your travels to Edisto Island. Wander the beautiful beaches in this relaxing area.
Bay Creek Park
Explore the great outdoors at Bay Creek Park, a lovely green space in Edisto Island. Wander the beaches and seaside while you're in the area.
beach near Spinnaker Beachhouses
Why not spend a lazy afternoon at beach near Spinnaker Beachhouses during your trip to Seabrook Island? Stroll along the marina or discover the sunsets in this relaxing area.
Plantation Course at Edisto
8.6/10 (7 reviews)
Enjoy a round of golf in Edisto Island at Plantation Course at Edisto. Wander the beautiful beaches in this relaxing area.
Frequently asked questions
Explore a world of travel with Expedia
- Hannah's Choice
- Seabrook Exclusives
- Kiawah Island Hotels
- Seabrook Exclusives
- Hotels near Golf Club at Briar's Creek
- 2 Family House Steps from Beach; 2 Master Bedrooms; Beach and Bike Equipment too
- Oceanfront Hotels in Edisto Island
- Dragonfly
- Ultimate BEACH AND GOLF COURSE HAVEN ON SECLUDED EDISTO IN THE WYNDHAM RESORT
- Muck IT
- King Street Hotels
- Dreamcatcher
- Edisto Beach Hotels
- West Beach Village Hotels
- The Pearl
- Beaufort Hotels
- Updated Second Floor Condo w/ Free Pool Access; Direct Beach Access; Cable TV/WiFi Access
- 2 bedroom+ Loft condo
- Seabrook Exclusives
- Shelter Cove 896
- Edisto Island
- Gorgeous Oceanfront 6 bdrm
- West Ashley Hotels
- “Going Coastal”
- North Charleston Hotels
- Creekside Cottage
- Oceanfront 1 Bedroom
- Johns Island Hotels
- Hotels near Middleton Place
- Charleston Kiawah Island/Andell Inn
- 493 Egrets Pointe
- Villas in Wadmalaw Island
- Hotels near Joseph P. Riley
- Hilton Hotels in Seabrook Island
- Saint Helena Island Hotels
- Lgbt Friendly Hotels in Seabrook Island
- Vanderhorst Plantation Hotels
- 5 Star Hotels in Spinnaker Beachhouses
- Edisto Sugar Shack
- Creekside Cottage
- Blue Heron Lake Hotels
- Downtown Charleston Hotels
- Seabrook Island Hotels
- Harleston Village Hotels
- Kiawah Island Golf Resort
- Hilton Head Island Hotels
- Wyndham Extra Holidays Hotels in Edisto Island
- The Sanctuary at Kiawah Island Golf Resort
- Boutique Hotels in Kiawah Island
- Making Memories
- Fripp Island Hotels
- Tiger's Roost
- Howe It Should Be
- Oceanfront Classic w/ Screened Porch & Sun Deck; Cable TV & WiFi
- Hotels near Edmonston-Alston House
- Blue Crab Basin
- Knot in Kansas; Pet
- Hotels near Charleston Intl.
- Marsh Cove
- Charleston Hotels
- Wyndham Ocean Ridge 2 bedroom deluxe condo with a full kitchen
- Folly Beach Hotels
- Hotels near Magnolia Plantation and Gardens
- I'll Have Another
- Seabrook Exclusives
- French Quarter Hotels
- 3 BR/3 BA Family Friendly Villa! Golf Views! Amenity access included!
- At Water's Edge
- Kiawah Island by Wyndham Vacation Rentals
- 1314 Pelican Watch Villas
- 5 Star Hotels in Edisto Beach
- Downtown Beaufort Hotels
- Vacation Homes in Edisto Island
- Apartments in Seabrook Island
- Cottages in Edisto Island
- Seabrook Exclusives
- 4 Bedrooms
- Charleston Historic District Hotels
- Romantic Hotels in Edisto Beach