Title: Book the Best BUSINESS Hotels in Eastern Panama in 2025 | Expedia.ca [Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.ca/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Eastern Panama ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Eastern Panama Business Hotels Tonight [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-09-24&endDate=2025-09-25&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-09-25&endDate=2025-09-26&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Eastern Panama Business Hotels We don't have any properties that match your exact search [See all properties in Eastern Panama](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=6246114&adults=2) ## Recommended hotels in Eastern Panama ![Living area](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/8c553055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/a3407ec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room, Patio, Beach View](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/5a5332f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Suite, Patio, Garden View](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/df779aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL ISLA GRANDE Isla Grande 6.0/10 (1) "Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting until 5 am. There are no amenities however the caribbean ocean is just outside the door. " CA $141 CA $156 total includes taxes & fees Sep 26 - Sep 27 [](https://www.expedia.ca/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/d88c1b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, individually decorated, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/f2796ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/729188af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ranchos de Chalia Puerto Lindo 9.6/10 Exceptional (5) "Perfect location" CA $191 CA $211 total includes taxes & fees Sep 27 - Sep 28 [](https://www.expedia.ca/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) ![Double Room, Ocean View](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/a3494600.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/3eaf0fae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/85a94096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, Ocean View](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/eda44167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cocotal Isla Grande 10/10 Exceptional (2) "Very rustic place but food is delicious and staff is super friendly and willing to help." CA $68 CA $136 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information) ![1 bedroom, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/6dc250bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Quadruple Room](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/cf61e7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/50019413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/2a230d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### B&B Lodgings 24 de Diciembre 7.8/10 Good (68) "The property is very secure." CA $66 CA $73 total includes taxes & fees Sep 26 - Sep 27 [](https://www.expedia.ca/Tocumen-Hotels-BB-Lodgings.h38712982.Hotel-Information) ![Deluxe Room](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gallery Room, 1 King Bed](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/657647d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/0f5b4937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/2321221d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ciel y Miel Cacique 10/10 Exceptional (9) "Love this place and would return back numerous times" CA $448 CA $493 total includes taxes & fees Sep 27 - Sep 28 [](https://www.expedia.ca/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) ![Family Room, 2 Bedrooms, Sea View (Casa Rayo) | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/8f40c1a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room, Bay View (Casa Rayo)](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/439b6ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Bedrooms, Sea View (Casa Rayo) | Private kitchen](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/f6f56668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/786f6559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Congo - Rayo Verde - Restaurante Portobelo 9.0/10 Wonderful (101) "Staff very polite and attentive, mainly Jorge he gave us very good suggestion about the city. Location nearby the city and beautiful hotel view." CA $94 CA $106 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Portobelo-Hotels-Casa-Congo-Rayo-Verde-Restaurante.h15362713.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/984fa3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/af0b1903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/10c4f3b1_edited_d046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/92085f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Posada del Buzo Portobelo 9.0/10 Wonderful (7) "We really liked that the staff was so helpful, friendly and outgoing especially to their non spanish speaking guests. The food was awesome, the beds so comfortable, the surroundings quiet and the views unbelievable. " CA $131 CA $147 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Portobelo-Hotels-Hotel-Panama-Dive-Adventure.h90295300.Hotel-Information) ![On the beach, white sand, snorkeling, beach bar](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/eb9f55f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/8e470218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/8696040b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/d29880fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Private Over-the-Water Cabin Narganá 8.0/10 Very good (2) "I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay... CA $347 CA $521 total includes taxes & fees Sep 26 - Sep 27 [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Over-The-Water-Cabin.h46949679.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/42000000/41270000/41265700/41265666/235e38a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/42000000/41270000/41265700/41265666/fc9d3d8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/42000000/41270000/41265700/41265666/48a71246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room | Porch](https://images.trvl-media.com/lodging/42000000/41270000/41265700/41265666/b004dccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private bedroom on paradise San Blas Island - Meals Included Narganá 10/10 Exceptional (1) "Don’t go expecting a resort and you will thoroughly enjoy yourself. The Guna that run the island are all warm, friendly, helpful. Great snorkelling tours and beautiful clean water. The accommodations are very simple but comfortable. Shared bathroom that was kept very clean. A great place to get away from it all. The ride through the mountain was very potholy and winding so if you get carsick definitely come prepared." CA $195 CA $215 total includes taxes & fees Sep 26 - Sep 27 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Isla-Yansailadup-Property.h41265666.Hotel-Information) ![Panoramic Cabin, Ocean View | Beach/ocean view](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/w2878h1920x0y0-df17b8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/caaaab49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/7708eca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Ocean-Front Cabin with private bathroom on San Blas Island Narganá CA $260 CA $286 total includes taxes & fees Sep 26 - Sep 27 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=6246114&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Eastern Panama Hotel Reviews