Title: Book the Best BUSINESS Hotels in East Side Pioneers in 2025 | Expedia.ca [Vacation Rentals in Rochester](https://expedia.ca/Rochester-Vacation-Rentals.d3041.Travel-Guide-VacationRentals)[Flights to Rochester](https://expedia.ca/Cheap-Flights-To-Rochester.d3041.Travel-Guide-Flights)[East Side Pioneers Car Rentals](https://expedia.ca/Car-Rentals-In-East-Side-Pioneers.d553248635976478182.Car-Rental-Guide)[East Side Pioneers Vacations](https://expedia.ca/East-Side-Pioneers.d553248635976478182.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in East Side Pioneers, MN from CA $101 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on East Side Pioneers Business Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976478182&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976478182&startDate=2025-10-25&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976478182&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976478182&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top East Side Pioneers Business Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/42f521a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester 8.8/10 Excellent (842) "Staff was kind in all my interactions. Hotel was clean and well cared for. The room itself was very nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy CA $124 CA $143 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, Multiple Beds | Living area](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/1213b471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area Downtown Rochester 9.6/10 Exceptional (523) "Great hotel and location. Will definitely select this property again for my next stay in Rochester. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $240 CA $276 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/a8a8ab63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two-Bedroom Apartment - Mobility Accessible/Non-Smoking](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/8523d385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/fa38f94a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/a26fee5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Broadway Plaza, Trademark Collection by Wyndham Downtown Rochester 9.2/10 Wonderful (164) "Great staff, clean room, spacious kitchen and living room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) silvia CA $238 CA $274 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Rochester-Hotels-Broadway-Plaza.h13173672.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/b1805314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/3613a59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/bac0b2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG Kutzky Park 9.4/10 Exceptional (922) "Great stay! Looking forward to coming back next time we’re in the area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cris CA $152 CA $178 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/fce6cfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South Rochester 9.4/10 Exceptional (226) "Check in was easy and staff was extremely helpful! We'll definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla CA $99 CA $114 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/fdcb0eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/055a808d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area Rochester 9.0/10 Wonderful (839) "Liked our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy CA $88 CA $101 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/12906a03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/f69df08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Rochester 7.2/10 Good (1017) "Thank you for a quick check in, beautiful and clean rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla CA $101 CA $116 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/86c17899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.2/10 Very good (1689) "Great location, beautiful hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $178 CA $205 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/5e158908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay movies](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/9d7d5e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Inn and Suites - Mayo Clinic Area Downtown Rochester 8.0/10 Very good (1471) "Very friendly and helpful staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monte CA $170 CA $196 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/a518fccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/10fbc765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brentwood Inn & Suites Downtown Rochester 8.8/10 Excellent (1001) "Decent room, clean and friendly staff! Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine CA $157 CA $181 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08®ionId=553248635976478182&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top East Side Pioneers Hotel Reviews ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Our room was very nice. It did accumulate dust from the construction across the street. Everyone was ver hospitable, even when our dogs were batking" [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](//images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Clean room but lots of permanent stains on walls. Yet by far the best 2 star hotel I’ve stayed at. Need a place to crash and not worry about bugs? This is it! Look no further. " [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Spark by Hilton Rochester South](//images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "The room and hotel were very clean and nice. The staff was so friendly and accommodating. My daughter had appointments at mayo and the drive was 10 minutes away. Super easy to get there. They do have a shuttle service to Mayo, but we just drove. I wish that there were more breakfast options. The bed was extremely comfortable and sheets were so soft. I would definitely stay here again when my daughter has her next appointments at mayo. " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Clean, comfortable room. Meeting space was very nice for our event. Excellent restaurant. " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hampton Inn Rochester-South](//images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Gentleman at desk was very nice. Good dining options " [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Broadway Plaza, Trademark Collection by Wyndham](//images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/a8a8ab63_y.jpg) ### Broadway Plaza, Trademark Collection by Wyndham 10/10 Excellent "Great staff, clean room, spacious kitchen and living room." [](https://expedia.ca/Rochester-Hotels-Broadway-Plaza.h13173672.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](//images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Everything good overall" [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "Fine. Comfortable. Nothing extra, just fine." [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](//images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Bathroom doors could be different, there barn style doors. Not very much privacy. No breakfast offered." 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