Title: Hotels by La Quinta Inn & Suites in East Seneca from CA $147 | Expedia.ca [East Seneca Travel Guide](https://expedia.ca/Buffalo-East-Seneca.dx553248635975848496)[Vacation Rentals in Buffalo](https://expedia.ca/Buffalo-Vacation-Rentals.d717.Travel-Guide-VacationRentals)[East Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-East-Seneca.d553248635975848496.Car-Rental-Guide)[East Seneca Vacations](https://expedia.ca/East-Seneca.d553248635975848496.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in East Seneca from CA $147 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-09-30&endDate=2025-10-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-10-01&endDate=2025-10-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635975848496&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top East Seneca La Quinta Inn & Suites Hotels ![Lobby](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/456d3072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/c16c966d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing, Tub w/Grab Bars)](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/b02c3e71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/f96730ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst Buffalo 8.4/10 Very good (1938) "It was a great stay" CA $145 CA $165 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/4969c4dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/a4c49971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/9614d0d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/f7f089be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Buffalo Airport Buffalo 7.8/10 Good (1263) "Great place" CA $131 CA $149 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Buffalo-Hotels-La-Quinta-Inn-By-Wyndham-Buffalo-Airport.h27531.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/b908b841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/a41dc4f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/3ba20a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1820000/1818500/1818414/2b63be0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Lackawanna Buffalo 6.4/10 (1016) "Enjoyed our stay." CA $129 CA $147 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lackawanna.h1818414.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-14&endDate=2025-10-15®ionId=553248635975848496&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEast-Seneca-Buffalo-Hotels-La-Quinta-Inn-Suites.0-n553248635975848496-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEast-Seneca-Buffalo-Hotels-La-Quinta-Inn-Suites.0-n553248635975848496-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top East Seneca Hotel Reviews ![Garden Place Hotel](//images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg) ### Garden Place Hotel 10/10 Excellent "Great room" [](https://expedia.ca/Buffalo-Hotels-Garden-Place-Hotel.h1060721.Hotel-Information) ![Hilton Garden Inn Buffalo Downtown](//images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/4777f940_y.jpg) ### Hilton Garden Inn Buffalo Downtown 10/10 Excellent "Great place" [](https://expedia.ca/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information) ![M Hotel Buffalo](//images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg) ### M Hotel Buffalo 10/10 Excellent "Great weekend stay for shopping. Hotel was clean and right beside the mall. Needs some updates but looks to be under renovations to address this. We had a great stay. " [](https://expedia.ca/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Sleep Inn & Suites Buffalo Airport](//images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d_y.jpg) ### Sleep Inn & Suites Buffalo Airport 10/10 Excellent "1. Location- seems like a nice area and Very close to airport and other hotels. 2.Food- 5 minute drive to restaurants and fastfood right down transit. 3.Room- Nice, i liked the stand up shower with the counter and mirror outside the room. Even for a lower priced basic room eince i only stayed 1 night it was perfect. Hotel-easy parking, pulled right up under the awnin, breakfast offered following morning(wasnt able to partake in that) Shuttle-quick ride to airport, driver was ok, helped with luggage. Staff- quick and easy check in. Although the desk employee was on her phone the whole time i was checking in and couldnt tell if she was talking to me or whoever was on the phone. Checking out was quick and easy. Overall good experiance would recoomend and will definately use again" [](https://expedia.ca/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Buffalo Amherst](//images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/456d3072_y.jpg) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst 10/10 Excellent "Very big and clean room. Parking was easy and breakfast was good" [](https://expedia.ca/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Wyndham Garden Buffalo Downtown](//images.trvl-media.com/lodging/1000000/160000/159000/158959/2e0799e1_y.jpg) ### Wyndham Garden Buffalo Downtown 10/10 Excellent "The location was great and not far from public transportation. The check-in/check-out process was easy. The staff was great and the room clean. " [](https://expedia.ca/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![Hampton Inn Buffalo - Amherst, NY](//images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/63fc013f_y.jpg) ### Hampton Inn Buffalo - Amherst, NY 10/10 Excellent "Very nice. " [](https://expedia.ca/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) ![CenterWay Hotel Tonawanda](//images.trvl-media.com/lodging/1000000/80000/76400/76371/66013c67_y.jpg) ### CenterWay Hotel Tonawanda 10/10 Excellent "Good place " [](https://expedia.ca/Buffalo-Hotels-CenterWay-Hotel-Tonawanda.h76371.Hotel-Information) ![Comfort Inn University](//images.trvl-media.com/lodging/1000000/70000/66600/66581/2db1a2f1_y.jpg) ### Comfort Inn University 10/10 Excellent "Excellent stay" [](https://expedia.ca/Buffalo-Hotels-Comfort-Inn-University.h66581.Hotel-Information) ## Find out more about East Seneca ## East Seneca Hotels Guide Expedia.ca offers a selection of 772 hotels in East Seneca. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in East Seneca. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the East Seneca neighborhood you prefer. Go ahead. 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[Flights to Cheektowaga](https://www.expedia.ca/Cheap-Flights-To-Cheektowaga.d7197.Travel-Guide-Flights) - [Flights from Buffalo Niagara Intl.](https://www.expedia.ca/lp/airports/buf/flights-from-buffalo-niagara-intl-airport) - [Flights from Toronto (YYZ) to Buffalo (BUF)](https://www.expedia.ca/lp/flights/yyz/buf/toronto-to-buffalo) - [Visit Cheektowaga](https://www.expedia.ca/Cheektowaga.dx7197) - [Holiday Twin Rinks](https://www.expedia.ca/Holiday-Twin-Rinks-Buffalo.d6207411.Vacation-Attraction) - [Walden Galleria Mall](https://www.expedia.ca/Walden-Galleria-Mall-Buffalo.d6129205.Vacation-Attraction) - [West Seneca Vacations](https://www.expedia.ca/West-Seneca.d602055.Destination-Travel-Guides) - [Advantage Rent-A-Car Rental Cars in Cheektowaga](https://www.expedia.ca/Advantage-Rent-A-Car-Car-Rentals-In-Cheektowaga.d7197-c3.Car-Rental-Guide-Suppliers) - [Alamo Rent A Car Rental Cars in Cheektowaga](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Cheektowaga.d7197-c6.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Cheektowaga](https://www.expedia.ca/Avis-Car-Rentals-In-Cheektowaga.d7197-c41.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Cheektowaga](https://www.expedia.ca/Budget-Car-Rentals-In-Cheektowaga.d7197-c39.Car-Rental-Guide-Suppliers) - [Car rental Cheektowaga](https://www.expedia.ca/Car-Rentals-In-Cheektowaga.d7197.Car-Rental-Guide) - [Dollar Rent A Car Rental Cars in Cheektowaga](https://www.expedia.ca/Dollar-Rent-A-Car-Car-Rentals-In-Cheektowaga.d7197-c43.Car-Rental-Guide-Suppliers) - [Enterprise Rental Cars in Cheektowaga](https://www.expedia.ca/Enterprise-Car-Rentals-In-Cheektowaga.d7197-c15.Car-Rental-Guide-Suppliers) - [Payless Rental Cars in Cheektowaga](https://www.expedia.ca/Payless-Car-Rentals-In-Cheektowaga.d7197-c38.Car-Rental-Guide-Suppliers) - [Cheektowaga Vacation Rentals](https://www.expedia.ca/Cheektowaga-Vacation-Rentals.d7197.Travel-Guide-VacationRentals) - [Things to do in Buffalo](https://www.expedia.ca/Things-To-Do-In-Buffalo.d602674.Travel-Guide-Activities) - [Things to do in Cheektowaga](https://www.expedia.ca/Things-To-Do-In-Cheektowaga.d7197.Travel-Guide-Activities) - [Things to do in West Seneca](https://www.expedia.ca/Things-To-Do-In-West-Seneca.d602055.Travel-Guide-Activities) - [Book Hotels in East Seneca on Expedia.com](https://www.expedia.com/East-Seneca-Hotels-La-Quinta-Inn-Suites.0-0-d553248635975848496--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)