Title: Book the Best East Main Street LUXURY Hotels - Upscale Hotels in East Main Street, Grand Junction | Expedia.ca

[East Main Street Travel Guide](https://expedia.ca/Grand-Junction-East-Main-Street.dx905402989559472128)[Vacation Rentals in Grand Junction](https://expedia.ca/Grand-Junction-Vacation-Rentals.d1331.Travel-Guide-VacationRentals)[Flights to Grand Junction](https://expedia.ca/Cheap-Flights-To-Grand-Junction.d1331.Travel-Guide-Flights)[Things to do in Grand Junction](https://expedia.ca/Things-To-Do-In-Grand-Junction.d1331.Travel-Guide-Activities)[East Main Street Car Rentals](https://expedia.ca/Car-Rentals-In-East-Main-Street.d905402989559472128.Car-Rental-Guide)[East Main Street Vacations](https://expedia.ca/East-Main-Street.d905402989559472128.Destination-Travel-Guides)

![Independence Monument in Colorado National Monument](https://images.trvl-media.com/place/905402989559472128/5147b9ae-8b45-4afa-98e4-37d3db040c9f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Luxury Hotels in East Main Street, Grand Junction

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## Check availability on East Main Street Luxury Hotels

Tonight

[Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-12-14&endDate=2025-12-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-12-15&endDate=2025-12-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-12-19&endDate=2025-12-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

In two weeks

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-12-26&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Top East Main Street Hotel Reviews

![Grand Vista Hotel](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/7dc2f4eb_y.jpg)

### Grand Vista Hotel

10/10 Excellent

"Room was spotless and the staff is very efficient and nice. There are always cleaning staff working on the lobby, hallways and rooms. Equally as professional and courteous as the front desk. I have stayed multiple times and am a works traveler. I have never experienced this value for the rate. "

[](https://expedia.ca/Grand-Junction-Hotels-Grand-Vista-Hotel.h14746.Hotel-Information)

![Wine Country Inn Palisade](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/3ecd4143_y.jpg)

### Wine Country Inn Palisade

10/10 Excellent

"All was great "

[](https://expedia.ca/Grand-Junction-Hotels-Wine-Country-Inn-Palisade.h2108693.Hotel-Information)

![Super 8 by Wyndham Grand Junction Colorado](https://images.trvl-media.com/lodging/1000000/440000/439800/439720/4c89f962_y.jpg)

### Super 8 by Wyndham Grand Junction Colorado

10/10 Excellent

"Great staff"

[](https://expedia.ca/Grand-Junction-Hotels-Super-8-By-Wyndham-Grand-Junction-Colorado.h439720.Hotel-Information)

![Doubletree Hotel Grand Junction](https://images.trvl-media.com/lodging/1000000/10000/7900/7802/f1ef5dcf_y.jpg)

### Doubletree Hotel Grand Junction

10/10 Excellent

"My stay was great! Thank you!"

[](https://expedia.ca/Grand-Junction-Hotels-Doubletree-Hotel-Grand-Junction.h7802.Hotel-Information)

![Comfort Inn & Suites](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/cdea8409_y.jpg)

### Comfort Inn & Suites

10/10 Excellent

"Staff was very polite and the rooms are really clean. Good selection at the breakfast bar "

[](https://expedia.ca/Grand-Junction-Hotels-Comfort-Inn-Suites.h471130.Hotel-Information)

![Clarion Inn Grand Junction](https://images.trvl-media.com/lodging/1000000/20000/10400/10322/64eb32ff_y.jpg)

### Clarion Inn Grand Junction

10/10 Excellent

"Very Clean, great beds, nice pool, great staff "

[](https://expedia.ca/Grand-Junction-Hotels-Clarion-Inn-Grand-Junction.h10322.Hotel-Information)

![Super 8 by Wyndham Fruita](https://images.trvl-media.com/lodging/1000000/450000/440400/440375/b7828347_y.jpg)

### Super 8 by Wyndham Fruita

10/10 Excellent

"The room is dated but clean, the staff has been great the two times I have been there! "

[](https://expedia.ca/Grand-Junction-Hotels-Super-8-By-Wyndham-Fruita.h440375.Hotel-Information)

![Red Roof Inn Grand Junction](https://images.trvl-media.com/lodging/10000000/9640000/9638600/9638544/cf2f138c_y.jpg)

### Red Roof Inn Grand Junction

10/10 Excellent

"Clean rooms, quiet, comfortable "

[](https://expedia.ca/Grand-Junction-Hotels-Red-Roof-Inn-Grand-Junction.h9638544.Hotel-Information)

## Frequently asked questions

### Are you looking for a luxury hotel for your East Main Street vacation?

### What's there to see and do in East Main Street?

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