Title: Book the Best East Main Street CASINO Hotels & Resorts in 2025 | Expedia.ca [East Main Street Travel Guide](https://expedia.ca/Grand-Junction-East-Main-Street.dx905402989559472128)[Vacation Rentals in Grand Junction](https://expedia.ca/Grand-Junction-Vacation-Rentals.d1331.Travel-Guide-VacationRentals)[Flights to Grand Junction](https://expedia.ca/Cheap-Flights-To-Grand-Junction.d1331.Travel-Guide-Flights)[Things to do in Grand Junction](https://expedia.ca/Things-To-Do-In-Grand-Junction.d1331.Travel-Guide-Activities)[East Main Street Car Rentals](https://expedia.ca/Car-Rentals-In-East-Main-Street.d905402989559472128.Car-Rental-Guide)[East Main Street Vacations](https://expedia.ca/East-Main-Street.d905402989559472128.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Casino Hotels in East Main Street, CO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on East Main Street Casino Hotels Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-10-18&endDate=2025-10-19&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-10-19&endDate=2025-10-20&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=905402989559472128&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top East Main Street Casino Hotels We don't have any properties that match your exact search [See all properties in East Main Street](https://expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03®ionId=905402989559472128&adults=2) ## Recommended hotels in East Main Street ![Terrace/patio](https://images.trvl-media.com/lodging/75000000/74900000/74896400/74896365/6704ff2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/75000000/74900000/74896400/74896365/01a42002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/75000000/74900000/74896400/74896365/774fc92b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/75000000/74900000/74896400/74896365/dd2fcc3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars. East Main Street 10/10 Exceptional (18) "Easy walk to the Avalon Theater, great bagel shop and brew pub." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael M. CA $201 CA $441 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Grand-Junction-Hotels-Downtown-Craftsman-Home-With-Hot-Tub-3-Blocks-From-Restaurants.h74896365.Hotel-Information) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/89cb7554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/bc2bdea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/ef5392d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/21581bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Grand Junction Horizon Drive District 8.8/10 Excellent (2612) "Very clean, friendly staff and good breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele CA $106 CA $122 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Grand-Junction-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Grand-Junction.h84495.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/cdea8409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/a80a6f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/f666e4b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/4bc46ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Fruita 8.4/10 Very good (1021) "Very nice place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $111 CA $127 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Grand-Junction-Hotels-Comfort-Inn-Suites.h471130.Hotel-Information) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/7dc2f4eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/6ef1420f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/750493ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/a2cd6a09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Vista Hotel Horizon Drive District 8.2/10 Very good (3435) "Great staff, clean rooms. Airport shuttle was a plus!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shane CA $78 CA $105 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Grand-Junction-Hotels-Grand-Vista-Hotel.h14746.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/79c5aded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/3c40d3dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/60b42f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/8c3d9d3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Grand Junction Horizon Drive District 8.4/10 Very good (1820) "I would definitely stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $87 CA $100 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Grand-Junction-Hotels-Ramada-By-Wyndham-Grand-Junction.h17140.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/3ecd4143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/0b44c017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/2e7baa84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/w3000h2022x0y2-11965b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Country Inn Palisade Palisade 9.6/10 Exceptional (1025) "We loved the location near the wineries. Great place to stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara CA $201 CA $224 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Grand-Junction-Hotels-Wine-Country-Inn-Palisade.h2108693.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9830000/9823200/9823186/eedd4cff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/10000000/9830000/9823200/9823186/b7b8ae83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/10000000/9830000/9823200/9823186/c8bbe145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/10000000/9830000/9823200/9823186/4e35f8d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Grande River Inn & Suites Clifton 9.0/10 Wonderful (774) "Clean facility, convenient location, pleasant & efficient staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerry CA $142 CA $149 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Grand-Junction-Hotels-Best-Western-Grande-River-Inn-Suites.h9823186.Hotel-Information) ![Monument "Not-so-tiny" Tiny Home (13) | Living area](https://images.trvl-media.com/lodging/82000000/81810000/81805900/81805819/b8947c22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Modern Tiny Home on the Colo. River (9)](https://images.trvl-media.com/lodging/82000000/81810000/81805900/81805819/5c67ac14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vintage Avion on the Colo. River (19) | Private kitchen](https://images.trvl-media.com/lodging/82000000/81810000/81805900/81805819/b009e52e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/82000000/81810000/81805900/81805819/6a0ad467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camp Eddy Pear Park 9.4/10 Exceptional (275) "Love this spot. Will stay here every time I come to the valley!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $86 CA $171 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Grand-Junction-Hotels-Camp-Eddy.h81805819.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/37000000/36250000/36248100/36248029/decaad5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/37000000/36250000/36248100/36248029/ff6eb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36250000/36248100/36248029/12bd3b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/37000000/36250000/36248100/36248029/d7adf0d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Grand Junction Downtown Downtown 9.2/10 Wonderful (917) "Would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig CA $140 CA $161 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Grand-Junction-Hotels-Tru-By-Hilton-Grand-Junction-Downtown.h36248029.Hotel-Information) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/5000000/4400000/4399900/4399864/964f7008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4400000/4399900/4399864/6b65fa87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4400000/4399900/4399864/423cf559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/5000000/4400000/4399900/4399864/d3ef0a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Grand Junction North Horizon Drive District 8.4/10 Very good (1006) "We loved the stay, location helped with both gas and food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erandy CA $86 CA $98 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Grand-Junction-Hotels-Econo-Lodge.h4399864.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03®ionId=905402989559472128&adults=2&amenities=CASINO&sort=RECOMMENDED&openPlayBack=true) ## Top East Main Street Hotel Reviews ## Frequently asked questions ### How many hotels that are good for gaming are there in East Main Street? > Hit the casinos and have a good night's sleep at one of Expedia's 22 lodging options close to the casinos in East Main Street. ### What is there to do in East Main Street? > Check out Dinosaur Journey, John McConnell Math and Science Center, or Cross Orchards Historic Site for a taste of local culture. Some attractions to visit in the area are Bananas Fun Park and Canyon View Park. Additionally, you might consider adding Western Colorado Botanical Gardens and Mesa County Fairgrounds to your itinerary. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels with an Indoor Pool in 24 Road Corridor](https://www.expedia.ca/24-Road-Corridor-Grand-Junction-Hotels-Hotels-With-Indoor-Pool.0-n905543688925843456-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in 24 Road Corridor](https://www.expedia.ca/24-Road-Corridor-Grand-Junction-Hotels-Pet-Friendly-Hotel.0-n905543688925843456-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Downtown](https://www.expedia.ca/2Star-Downtown-Grand-Junction-Hotels.s20-n905400057684393984-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Grand Junction](https://www.expedia.ca/5Star-Grand-Junction-Hotels.s50-0-d1331.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in 7th Street Historic District](https://www.expedia.ca/7th-Street-Historic-District-Grand-Junction-Hotels-Pet-Friendly-Hotel.0-n905400773140381696-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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