Title: Hotels by Independent in East Cape Girardeau from CA $87 | Expedia.ca [East Cape Girardeau Travel Guide](https://expedia.ca/East-Cape-Girardeau.dx553248634983574328)[Hotels in East Cape Girardeau](https://expedia.ca/East-Cape-Girardeau-Hotels.d553248634983574328.Travel-Guide-Hotels)[Vacation Rentals in East Cape Girardeau](https://expedia.ca/East-Cape-Girardeau-Vacation-Rentals.d553248634983574328.Travel-Guide-VacationRentals)[Flights to East Cape Girardeau](https://expedia.ca/Cheap-Flights-To-East-Cape-Girardeau.d553248634983574328.Travel-Guide-Flights)[East Cape Girardeau Car Rentals](https://expedia.ca/Car-Rentals-In-East-Cape-Girardeau.d553248634983574328.Car-Rental-Guide)[East Cape Girardeau Vacation Packages](https://expedia.ca/East-Cape-Girardeau.d553248634983574328.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 2 - Feb 3](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 3 - Feb 4](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-02-03&endDate=2026-02-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for East Cape Girardeau Independent ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jackpot Suite | Living area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/e87009c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (496 reviews) "The room was clean and I was able to check in a bit early." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara CA $128 CA $145 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/3bfecde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/5e9ee6eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/8928d3dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/e7ab16b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel 7 Inn Anna [](https://www.expedia.ca/Anna-Hotels-Hotel-7-Inn-Anna.h8295732.Hotel-Information) Anna 6.6/10 (218 reviews) "Room needs updates. Staff was great. Breakfast wasn't worth noting. Could use better breakfast options. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jody CA $119 CA $139 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Anna-Hotels-Hotel-7-Inn-Anna.h8295732.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking (NRF)](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/464a0039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/f2b68c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) Cape Girardeau 6.2/10 (210 reviews) "Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $75 CA $87 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2abc797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/ef0f7e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Accessible, Kitchenette | Bathroom](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/46ce3d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (432 reviews) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $91 CA $99 total includes taxes & fees Mar 5 - Mar 6 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/35000000/34340000/34332000/34331993/cb67aaf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34340000/34332000/34331993/b3778f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34340000/34332000/34331993/5387ea90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/35000000/34340000/34332000/34331993/42428d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest [](https://www.expedia.ca/Jonesboro-Hotels-Cabin-In-Southern-Illinois-Hot-Tub-Romantic-Getaway-Shawnee-National-Forest.h34331993.Hotel-Information) Jonesboro 10/10 Exceptional (271 reviews) "Great little cabin! Perfect for a couples get away along the wine trails of sourthern IL! Hot tub was fantastic, the property was very clean! The cabin had everything we needed! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla G. [](https://www.expedia.ca/Jonesboro-Hotels-Cabin-In-Southern-Illinois-Hot-Tub-Romantic-Getaway-Shawnee-National-Forest.h34331993.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/7794c781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/9f324b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 2 Bedrooms, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fd5c34e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn [](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) Cape Girardeau 10/10 Exceptional (19 reviews) "My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim CA $212 CA $240 total includes taxes & fees Mar 5 - Mar 6 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107210000/107206800/107206793/857bfe51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107210000/107206800/107206793/1a815356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/108000000/107210000/107206800/107206793/cde03009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107210000/107206800/107206793/c4f4975c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW property! Lakeside covered hot tub, A-frame 3 King Beds, Shawnee Forest [](https://www.expedia.ca/Jonesboro-Hotels-A-Frame-Lakeside-3-King-Beds-Covered-Hot-Tub-Shawnee-National-Forest.h107206793.Hotel-Information) Jonesboro 10/10 Exceptional (46 reviews) "Such a fun stay! The lodge is adorable and it’s the perfect little getaway!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Summar B. [](https://www.expedia.ca/Jonesboro-Hotels-A-Frame-Lakeside-3-King-Beds-Covered-Hot-Tub-Shawnee-National-Forest.h107206793.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/58000000/57130000/57120600/57120575/9a3acd84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/58000000/57130000/57120600/57120575/9f159f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/58000000/57130000/57120600/57120575/8f64052e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/58000000/57130000/57120600/57120575/9105b7a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen [](https://www.expedia.ca/Anna-Hotels-Spacious-2-BR.h57120575.Hotel-Information) Anna 9.8/10 Exceptional (168 reviews) "Was the second time we’ve stayed at the property and it was just as great as the last time" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris H. [](https://www.expedia.ca/Anna-Hotels-Spacious-2-BR.h57120575.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/1c1368ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/b8327ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/f4fbd89f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/0b3aaea0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Twisted Sassafras Treehouse [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information) Cape Girardeau 10/10 Exceptional (30 reviews) "This is the perfect private romantic getaway! We had such a blast here. Definitely recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric S. CA $293 CA $429 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/09707f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/30627e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/c221a56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming cottage overlooking Lake Acre [](https://www.expedia.ca/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) Dongola 10/10 Exceptional (102 reviews) "Location was great, everything was great for what we were there for. Already booked again for November. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) carlton h. CA $184 CA $387 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17®ionId=553248634983574328&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEast-Cape-Girardeau-Hotels-Independent.0-0-d553248634983574328--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEast-Cape-Girardeau-Hotels-Independent.0-0-d553248634983574328--bIndependent.Travel-Guide-Filter-Hotels) ## Top East Cape Girardeau Hotel Reviews ![Hampton Inn Cape Girardeau I 55 East](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg) ### Hampton Inn Cape Girardeau I 55 East 10/10 Excellent "Nice staff. Clean room. Good cookies. And breakfast adequate. " [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "The room was lage and clean. We really enjoyed the free food and drinks provided." [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "The lady at the front desk was an amazing person and treated me with the upmost respect " [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Yes everything was great" [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Comfortable beds and pillows Good breakfast " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 10/10 Excellent "Yes" [](https://expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "This place feels like customer service from 1950\. The service was outstanding " [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "Very nice room!" [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Clean room with friendly staff." [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [5 Star Hotels in Pomona ](https://www.expedia.ca/5Star-Pomona-Hotels.s50-0-d553248635592817265.Travel-Guide-Filter-Hotels) - [Apartments in Alto Pass ](https://www.expedia.ca/Alto-Pass-Apartments.d73449-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Alto Pass ](https://www.expedia.ca/Alto-Pass-Cabins.d73449-aaCabins.Travel-Guide-Accommodation) - [Alto Pass Hotels ](https://www.expedia.ca/Alto-Pass-Hotels.d73449.Travel-Guide-Hotels) - [Resorts in Alto Pass ](https://www.expedia.ca/Alto-Pass-Resort-Hotels.d73449-aaResortHotels.Travel-Guide-Accommodation) - [Farmstay in Anna ](https://www.expedia.ca/Anna-Agritourism.d6406-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Anna ](https://www.expedia.ca/Anna-Bed-And-Breakfast.d6406-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Chalets in Anna ](https://www.expedia.ca/Anna-Chalets.d6406-aaChalets.Travel-Guide-Accommodation) - 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