Title: 10 Best Hotels in Downtown South San Francisco, San Francisco for 2026 | Expedia.ca

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![Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015](https://images.trvl-media.com/place/553248635976481411/4dd74f8a-dfcd-4623-817e-767c96ff0c5c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/553248635976481411/4dd74f8a-dfcd-4623-817e-767c96ff0c5c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Tonight

[Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Downtown South San Francisco hotels

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/4becccdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/3bdf7c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/6c7a44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham San Francisco Airport N

[](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information)

Downtown South San Francisco

8.0/10

Very good

(2,021 reviews)

"Awsome rooms clean overall great experience "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

manuel

CA $139

CA $164 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/779a738f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/380e42eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/466a0c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/b1cfa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Airport Inn

[](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information)

Downtown South San Francisco

8.8/10

Excellent

(979 reviews)

"Very clean room, friendly staff and secure parking."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christopher

CA $136

CA $160 total

includes taxes & fees

Jan 24 - Jan 25

[](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/08473f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/9b3dc53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/72fd4af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/b9912bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn By The SFO

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information)

Downtown South San Francisco

7.8/10

Good

(1,001 reviews)

"Everything great. Good location close to airport and walking distance to coffee, market, and restaurants. Try shabu shack!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gabriel

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information)

![Deluxe Room](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/1e2e26cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/60ad2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/53069e9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/d205a5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Miller Apartments

[](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information)

Downtown South San Francisco

7.4/10

Good

(15 reviews)

"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Kasey

CA $103

CA $225 total

includes taxes & fees

Jan 24 - Jan 25

[](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/cd59b3af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/fb03adf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/75f20517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Riu Plaza Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

16.7 km from Downtown South San Francisco

9.0/10

Wonderful

(7,294 reviews)

"Nice location, GREAT breakfast, friendly staff, comfortable room"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

CA $164

CA $249 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/8f783f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free self parking](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/7f0846e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/79349a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/48be1750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Aura SFO

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aura-SFO.h1080604.Hotel-Information)

4.4 km from Downtown South San Francisco

9.0/10

Wonderful

(2,573 reviews)

"Good hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Victor

CA $135

CA $162 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aura-SFO.h1080604.Hotel-Information)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/575b2d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/ac2abcd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/381993a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach/ocean view](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/67096996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Caza Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information)

16.7 km from Downtown South San Francisco

9.0/10

Wonderful

(3,823 reviews)

"Nice place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Harold Franklin

CA $179

CA $277 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/d9a28cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/c37b3c13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/6a4c1f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/fcb07f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Zoe Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information)

16.6 km from Downtown South San Francisco

9.2/10

Wonderful

(1,680 reviews)

"The hotel was very nice and located near many attractions. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sergio

CA $147

CA $232 total

includes taxes & fees

Feb 10 - Feb 11

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/1000000/10000/900/828/550e44fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/900/828/5dd21b54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/10000/900/828/0b6c9ec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/900/828/10ee0463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information)

9.3 km from Downtown South San Francisco

8.6/10

Excellent

(1,440 reviews)

"Very nice hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary Ann

CA $132

CA $150 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/74bf4ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/c107a1f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, 1 King Bed with Sofa bed | Living room](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/a9e1104a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/51c31a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information)

6.9 km from Downtown South San Francisco

8.8/10

Excellent

(1,994 reviews)

"Very nice hotel! The restaurant food and drinks were amazing !"

![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg)

Risa

CA $169

CA $235 total

includes taxes & fees

Jan 24 - Jan 25

[](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/85c9e6e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast served, American cuisine](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/9e8dcf27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/8d3345b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/2bfcf187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton San Francisco Airport Bayfront

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information)

9.9 km from Downtown South San Francisco

8.6/10

Excellent

(2,885 reviews)

"The room and breakfast was perfect "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniel

CA $139

CA $158 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/47630b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/d25eaf84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/339fb7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/24300/24251/26b347aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Dylan at SFO

[](https://www.expedia.ca/San-Francisco-Hotels-The-Dylan-At-SFO.h24251.Hotel-Information)

7.1 km from Downtown South San Francisco

9.2/10

Wonderful

(1,837 reviews)

"great hotel, well designed, comfortable beds, easy access to the bart and aiport"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alan

CA $136

CA $163 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/San-Francisco-Hotels-The-Dylan-At-SFO.h24251.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/96ca1121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 King Bed, Balcony, Bay View | Living area](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/a2b2e8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/0df576f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton San Francisco Financial District

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

15.4 km from Downtown South San Francisco

8.8/10

Excellent

(2,322 reviews)

"We loved our stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christine

CA $146

CA $172 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/20000000/19520000/19510300/19510249/9a7fa76b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/20000000/19520000/19510300/19510249/367e099d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/20000000/19520000/19510300/19510249/80f50688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, 1 Queen Bed with Sofa bed (VIP)](https://images.trvl-media.com/lodging/20000000/19520000/19510300/19510249/10d0c1c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### YOTEL San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-YOTEL-San-Francisco.h19510249.Hotel-Information)

13.8 km from Downtown South San Francisco

8.2/10

Very good

(1,002 reviews)

"Great place to stay in the city. Rooms are small but modern and clean staff is courteous and friendly. There is 24 hour security its a great place and is affordable."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sherretha

CA $106

CA $181 total

includes taxes & fees

Jan 26 - Jan 27

[](https://www.expedia.ca/San-Francisco-Hotels-YOTEL-San-Francisco.h19510249.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/173b8dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/4817709a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/19abbe84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/7bc06dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Zephyr San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information)

16.8 km from Downtown South San Francisco

8.6/10

Excellent

(2,388 reviews)

"The balcony view was amazing and parking was perfect. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ena M

CA $173

CA $261 total

includes taxes & fees

Jan 28 - Jan 29

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/f5fef020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/42a1392c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/c342f829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/738fe5d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-Aloft-San-Francisco-Airport.h13950.Hotel-Information)

6.9 km from Downtown South San Francisco

9.0/10

Wonderful

(2,256 reviews)

"Great place! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jon

CA $159

CA $183 total

includes taxes & fees

Feb 14 - Feb 15

[](https://www.expedia.ca/San-Francisco-Hotels-Aloft-San-Francisco-Airport.h13950.Hotel-Information)

![Building design](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/5ec6ba9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/71a1e5ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/cbb2553d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/ff2e5eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Aluxor SFO

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aluxor-SFO.h902027.Hotel-Information)

3.8 km from Downtown South San Francisco

8.6/10

Excellent

(2,691 reviews)

"Nice place, would stay again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alondra

CA $120

CA $146 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aluxor-SFO.h902027.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/63a5d8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/18d49d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, a heated pool, open 8 AM to 8 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/4fd95a3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Handlery Union Square Hotel

[](https://www.expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information)

14.5 km from Downtown South San Francisco

8.8/10

Excellent

(2,839 reviews)

"Great location, room was clean and staff was helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

CA $175

CA $206 total

includes taxes & fees

Jan 24 - Jan 25

[](https://www.expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Kitchenette (with Terrace)](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/acf84b9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Kitchenette (with Terrace)](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/a4142b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Kitchenette (with Terrace)](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/8e808fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Club Quarters Hotel in San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information)

15.4 km from Downtown South San Francisco

9.0/10

Wonderful

(2,917 reviews)

"nice location"

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Natthaya

CA $147

CA $173 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/5971a3e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/a67c7266.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9:00 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/8e61a8e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Golden Gateway by IHG

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

14.8 km from Downtown South San Francisco

9.0/10

Wonderful

(5,164 reviews)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos Emiro

CA $164

CA $193 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-07&regionId=553248635976481411&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. 

- Union Square
- Downtown San Francisco
- Fisherman's Wharf
- South of Market
- Nob Hill

![Union Square featuring a city and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22611-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square featuring a city, street scenes and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173736-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square featuring a city, a monument and a square or plaza](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173470-Northern-California.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square showing street scenes and a city as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/67000/67250-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square showing street scenes, a city and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173732-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800129)

![Union Square map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:owseFngdjV_H%7BeAzRuBna%40%7Ej%40qPdCn%40pIwDv%40n%40tGaXjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=vbtXVjtvbbFJoglIicZiXTBOs3E=)

### Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800129)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476363-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476367-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476362-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476359-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476366-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6151902)

![Downtown San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:m%7EteFvzejViZadFhsAmj%40%60lBaHdLhWlEviCoQtFoGdcByHdFwR%7BUc%60ChY&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=gvmSEImu4_lfi0gTpvxWcEmihx8=)

### Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6151902)

![Fisherman\'s Wharf featuring a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240986-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/548000/548532-fishermans-wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Fisherman\'s Wharf which includes a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173418-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Fisherman\'s Wharf which includes a fountain](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240993-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173428-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800128)

![Fisherman's Wharf map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mrweFnpfjVaIcEiDic%40wAal%40xF_c%40bZoH%60N%7CwBeMnBaIpEsF%7E%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=cSLnJ-bErQxSUv6GQKloGDHAW70=)

### Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800128)

![South of Market showing skyline, a city and city views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173326-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market showing a fountain, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173924-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market featuring a city, a skyscraper and central business district](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173938-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market featuring skyline, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173935-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market featuring city views and a city as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173937-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=160166)

![South of Market map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eipeF%7CxejVcaDsjEjv%40gt%40ffCuYvGdhDsKvBsD%7CF%7DBz%5BoCx%7C%40_E%7EGqC%7EA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ffiqKO1x2yhUpPKU2D52Jx63lg4=)

### South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=160166)

![Nob Hill featuring street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173402-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173400-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173393-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173395-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill featuring street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173391-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=138629)

![Nob Hill map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:q%7EteFvxejVmIopAll%40cHnIppAol%40%60H&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Skcsr6ZgxKZlWMjutOt189xwFug=)

### Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=138629)

## Top Downtown South San Francisco Hotel Reviews

![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg)

### Hyatt Centric Fisherman's Wharf San Francisco

10/10 Excellent

"Great stay"

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information)

![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg)

### Handlery Union Square Hotel

10/10 Excellent

"The staff was wonderful. The room was very clean and spacious. Loved the charm!"

[](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information)

![Bay Landing San Francisco Airport Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1110800/1110785/0c231d9b_y.jpg)

### Bay Landing San Francisco Airport Hotel

10/10 Excellent

"Very convenient, comfortable, and a good price."

[](https://expedia.ca/San-Francisco-Hotels-Bay-Landing-San-Francisco-Airport-Hotel.h1110785.Hotel-Information)

![Hyatt Regency San Francisco](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg)

### Hyatt Regency San Francisco

10/10 Excellent

"There was not parking at the hotel"

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information)

![Marriott Vacation Club®, San Francisco](https://images.trvl-media.com/lodging/38000000/37390000/37382500/37382494/0671fcfa_y.jpg)

### Marriott Vacation Club®, San Francisco

10/10 Excellent

"We had a great stay, staff was friendly and we were allowed to check-in early! "

[](https://expedia.ca/San-Francisco-Hotels-Marriott-Vacation-Club-Pulse.h37382494.Hotel-Information)

![DoubleTree by Hilton Hotel Berkeley Marina](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg)

### DoubleTree by Hilton Hotel Berkeley Marina

10/10 Excellent

"I love this place"

[](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information)

![Hotel Caza Fisherman's Wharf](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/575b2d5c_y.jpg)

### Hotel Caza Fisherman's Wharf

10/10 Excellent

"Extremely happy with out stay at Caza!!"

[](https://expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information)

![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg)

### Hotel Riu Plaza Fisherman's Wharf

10/10 Excellent

"Absolutely wonderful stay here at the Riu. This is our destination from now on when we come to SF."

[](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

![Hyatt Place San Francisco Downtown](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/fc76649d_y.jpg)

### Hyatt Place San Francisco Downtown

10/10 Excellent

"Yes"

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information)

## Frequently asked questions

### What's it like in Downtown South San Francisco?

### What's a favorite place to stay in Downtown South San Francisco?

### How many hotels will I find in the Downtown South San Francisco area?

### If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

### What can I see and do in this South San Francisco neighborhood?

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- [Visitacion Valley Hotels ](https://www.expedia.ca/Visitacion-Valley-San-Francisco-Hotels.0-n553248635976480925-0.Travel-Guide-Filter-Hotels)

- [Flights to San Francisco ](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)
- [Flights to South San Francisco ](https://www.expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights)
- [Flights from Los Angeles (LAX) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/lax/sfo/los-angeles-to-san-francisco)
- [Flights from Edmonton (YEG) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yeg/sfo/edmonton-to-san-francisco)
- [Flights from Montreal (YUL) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yul/sfo/montreal-to-san-francisco)
- [Flights from Vancouver (YVR) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco)
- [Flights from Calgary (YYC) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyc/sfo/calgary-to-san-francisco)
- [Flights from Toronto (YYZ) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco)

- [Visit Paradise Valley ](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811)
- [South San Francisco Vacations ](https://www.expedia.ca/South-San-Francisco.d6773.Destination-Travel-Guides)
- [Visit South San Francisco ](https://www.expedia.ca/South-San-Francisco.dx6773)

- [Rental cars San Francisco Intl. airport ](https://www.expedia.ca/Car-Rentals-In-San-Francisco-Intl.d5195347.Car-Rental-Guide)
- [Car rental South San Francisco ](https://www.expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide)
- [Enterprise Rental Cars in South San Francisco ](https://www.expedia.ca/Enterprise-Car-Rentals-In-South-San-Francisco.d6773-c15.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in South San Francisco ](https://www.expedia.ca/Hertz-Car-Rentals-In-South-San-Francisco.d6773-c40.Car-Rental-Guide-Suppliers)

- [South San Francisco Vacation Rentals ](https://www.expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals)

- [Things to do in South San Francisco ](https://www.expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities)

- [Book Hotels in Downtown South San Francisco on Expedia.com ](https://www.expedia.com/Downtown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels)