Title: 10 Best Hotels in Downtown South San Francisco, San Francisco for 2026 | Expedia.ca

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![Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015](https://images.trvl-media.com/place/553248635976481411/4dd74f8a-dfcd-4623-817e-767c96ff0c5c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Hotels in Downtown South San Francisco, San Francisco 

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## Check prices for these dates

Tonight

[Dec 31 - Jan 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-12-31&endDate=2026-01-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 1 - Jan 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-01-01&endDate=2026-01-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Downtown South San Francisco hotels

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/f426e9e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/6c7a44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/3bdf7c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham San Francisco Airport N

[](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information)

Downtown South San Francisco

8.0/10

Very good

(2011)

"Clean room, staff were friendly, breakfast was good, parking was good, overall we're satisfied!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Edna

CA $138

CA $163 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/779a738f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/466a0c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/8dc758c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/72b32b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Airport Inn

[](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information)

Downtown South San Francisco

8.8/10

Excellent

(972)

"Very clean room, friendly staff and secure parking."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christopher

CA $121

CA $143 total

includes taxes & fees

Jan 25 - Jan 26, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information)

![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/48a324c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/60ad2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/d205a5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/a007dfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Miller Apartments

[](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information)

Downtown South San Francisco

7.4/10

Good

(15)

"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Kasey

CA $100

CA $221 total

includes taxes & fees

Jan 5 - Jan 6, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/aeecf8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/9b3dc53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/b9912bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/72fd4af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn By The SFO

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information)

Downtown South San Francisco

7.8/10

Good

(1000)

"Excellent property!!! I would definitely recommend!!! Great stay!!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/e62e0c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/2aabc067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/75f20517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Riu Plaza Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

16.7 km from Downtown South San Francisco

9.0/10

Wonderful

(7218)

"Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isaiah

CA $137

CA $217 total

includes taxes & fees

Jan 5 - Jan 6, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/575b2d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/ac2abcd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/c37460ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Caza Fisherman's Wharf

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information)

16.7 km from Downtown South San Francisco

9.0/10

Wonderful

(3840)

"Excellent stay and great location! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

CHRISTINE

CA $167

CA $259 total

includes taxes & fees

Jan 30 - Jan 31, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/74bf4ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, 1 King Bed with Sofa bed | Living room](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/a9e1104a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/51c31a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/c107a1f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information)

6.8 km from Downtown South San Francisco

8.8/10

Excellent

(2020)

"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carole

CA $141

CA $202 total

includes taxes & fees

Jan 3 - Jan 4, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/01096013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 King Bed, Balcony, Bay View | Living area](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/9eb9cbe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 King Bed, Balcony, Bay View | Living area](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/a2b2e8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton San Francisco Financial District

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

15.4 km from Downtown South San Francisco

8.6/10

Excellent

(2210)

"We loved our stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christine

CA $122

CA $144 total

includes taxes & fees

Jan 8 - Jan 9, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

![Breakfast served, American cuisine](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/7b6b8635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/85c9e6e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/0944bb87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/bd21a30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton San Francisco Airport Bayfront

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information)

9.9 km from Downtown South San Francisco

8.6/10

Excellent

(2788)

"Breakfast was very good, many options to choose. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hourn

CA $144

CA $163 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/f5fef020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/5111543a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/738fe5d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/14000/13950/42a1392c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aloft San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-Aloft-San-Francisco-Airport.h13950.Hotel-Information)

6.9 km from Downtown South San Francisco

9.0/10

Wonderful

(2229)

"Spotless — not fancy but clean open and comfortable !!! Great airport hotel!!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

CA $154

CA $177 total

includes taxes & fees

Jan 3 - Jan 4, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Aloft-San-Francisco-Airport.h13950.Hotel-Information)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/1000000/10000/900/828/550e44fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception hall](https://images.trvl-media.com/lodging/1000000/10000/900/828/61c6362f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/900/828/0c032699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Banquet hall](https://images.trvl-media.com/lodging/1000000/10000/900/828/184531b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information)

9.3 km from Downtown South San Francisco

8.6/10

Excellent

(1398)

"Great location and staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ernest Dean

CA $156

CA $178 total

includes taxes & fees

Jan 17 - Jan 18, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/2603f5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/f5709844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/d57a5126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/890000/880800/880752/596146db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Inn & Suites San Mateo - San Francisco Airport

[](https://www.expedia.ca/San-Francisco-Hotels-Best-Western-Coyote-Point-Inn.h880752.Hotel-Information)

11.8 km from Downtown South San Francisco

9.0/10

Wonderful

(1256)

"Good place to stay, clean and good breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Xiaohong

CA $129

CA $149 total

includes taxes & fees

Jan 3 - Jan 4, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Best-Western-Coyote-Point-Inn.h880752.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/adbfb37e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/54d37611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free self parking](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/7f0846e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1090000/1080700/1080604/3cfbef02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Aura SFO

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aura-SFO.h1080604.Hotel-Information)

4.4 km from Downtown South San Francisco

9.0/10

Wonderful

(2553)

"Clean, quiet, close to the airport."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

RICHARD

CA $122

CA $147 total

includes taxes & fees

Jan 6 - Jan 7, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aura-SFO.h1080604.Hotel-Information)

![Game room](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fd976170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fecca267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/d2ac54ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/a3393d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Zephyr San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information)

16.8 km from Downtown South San Francisco

8.6/10

Excellent

(2345)

"Great location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Deborah

CA $171

CA $250 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/57907250.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/588fe135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/49e7095c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chancellor Hotel on Union Square

[](https://www.expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information)

14.7 km from Downtown South San Francisco

9.4/10

Exceptional

(3113)

"Clean room, helpful staff and great location to explore de city."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alan

CA $104

CA $122 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/7d695984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Kitchenette (with Terrace)](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/acf84b9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/4c4de4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Club Quarters Hotel in San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information)

15.4 km from Downtown South San Francisco

8.8/10

Excellent

(2844)

"Clean room, friendly staff and good location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jose Eduardo

CA $122

CA $144 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information)

![Outdoor pool, open 9:00 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/d650815d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/8e61a8e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/1b544d3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Golden Gateway by IHG

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

14.8 km from Downtown South San Francisco

9.0/10

Wonderful

(5056)

"Nice stay. Hotel was clean, quiet and accessible. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brandon

CA $163

CA $192 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6c2cdc12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 Queen Bed, Accessible](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/w1781h1201x19y0-3696f576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/3daecce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6a2ba7f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Nikko San Francisco

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information)

14.3 km from Downtown South San Francisco

9.4/10

Exceptional

(2658)

"Great service, great location, great hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

CA $208

CA $308 total

includes taxes & fees

Jan 24 - Jan 25, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/9f22ad54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Loft, 1 Bedroom, Balcony, Golf View](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/1d228ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/0992f574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/41197a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Half Moon Bay Lodge

[](https://www.expedia.ca/Half-Moon-Bay-Hotels-Half-Moon-Bay-Lodge.h11624.Hotel-Information)

24.9 km from Downtown South San Francisco

9.0/10

Wonderful

(1090)

"Always great staff here, nice rooms, nice jacuzzi "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Pamela

CA $170

CA $200 total

includes taxes & fees

Jan 28 - Jan 29, 2026

[](https://www.expedia.ca/Half-Moon-Bay-Hotels-Half-Moon-Bay-Lodge.h11624.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/b406d764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/927fa680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/08bf549c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/w5614h3742x0y0-0021dd27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express and Suites Fisherman's Wharf by IHG

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Express-And-Suites-Fishermans-Wharf.h578899.Hotel-Information)

16.6 km from Downtown South San Francisco

9.2/10

Wonderful

(2248)

"Awesome place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mark Anthony

CA $163

CA $236 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Express-And-Suites-Fishermans-Wharf.h578899.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-14&endDate=2026-01-15&regionId=553248635976481411&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. 

- Union Square
- Downtown San Francisco
- Fisherman's Wharf
- South of Market
- Nob Hill

![Union Square featuring a city and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22611-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square featuring a city, street scenes and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173736-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square featuring a city, a monument and a square or plaza](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173470-Northern-California.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square showing street scenes and a city as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/67000/67250-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Union Square showing street scenes, a city and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173732-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800129)

![Union Square map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:owseFngdjV_H%7BeAzRuBna%40%7Ej%40qPdCn%40pIwDv%40n%40tGaXjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=vbtXVjtvbbFJoglIicZiXTBOs3E=)

### Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800129)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476363-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476367-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476362-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476359-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476366-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6151902)

![Downtown San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:m%7EteFvzejViZadFhsAmj%40%60lBaHdLhWlEviCoQtFoGdcByHdFwR%7BUc%60ChY&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=gvmSEImu4_lfi0gTpvxWcEmihx8=)

### Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6151902)

![Fisherman\'s Wharf featuring a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240986-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/548000/548532-fishermans-wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Fisherman\'s Wharf which includes a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173418-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Fisherman\'s Wharf which includes a fountain](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240993-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173428-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800128)

![Fisherman's Wharf map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mrweFnpfjVaIcEiDic%40wAal%40xF_c%40bZoH%60N%7CwBeMnBaIpEsF%7E%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=cSLnJ-bErQxSUv6GQKloGDHAW70=)

### Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800128)

![South of Market showing skyline, a city and city views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173326-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market showing a fountain, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173924-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market featuring a city, a skyscraper and central business district](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173938-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market featuring skyline, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173935-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![South of Market featuring city views and a city as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173937-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=160166)

![South of Market map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eipeF%7CxejVcaDsjEjv%40gt%40ffCuYvGdhDsKvBsD%7CF%7DBz%5BoCx%7C%40_E%7EGqC%7EA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ffiqKO1x2yhUpPKU2D52Jx63lg4=)

### South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=160166)

![Nob Hill featuring street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173402-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173400-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173393-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173395-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Nob Hill featuring street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173391-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=138629)

![Nob Hill map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:q%7EteFvxejVmIopAll%40cHnIppAol%40%60H&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Skcsr6ZgxKZlWMjutOt189xwFug=)

### Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=138629)

## Top Downtown South San Francisco Hotel Reviews

![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg)

### Chancellor Hotel on Union Square

10/10 Excellent

"The staff were wonderful, the room was perfect and it is in a great neighborhood. We will stay there again soon. "

[](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information)

![Hilton San Francisco Airport Bayfront](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/7b6b8635_y.jpg)

### Hilton San Francisco Airport Bayfront

10/10 Excellent

"."

[](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information)

![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg)

### Hyatt Centric Fisherman's Wharf San Francisco

10/10 Excellent

"Everything was amazing thank you!! Spencer Potter"

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information)

![The Marina Inn on San Francisco Bay](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/095a2e83_y.jpg)

### The Marina Inn on San Francisco Bay

10/10 Excellent

"Room was clean, staff was awesome, and the view from the balcony was great. Onto a quiet stay."

[](https://expedia.ca/Oakland-Hotels-The-Marina-Inn-On-San-Francisco-Bay.h51116.Hotel-Information)

![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg)

### Hilton San Francisco Financial District

10/10 Excellent

"We loved our stay! "

[](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

![Hyatt Place San Francisco Downtown](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/fc76649d_y.jpg)

### Hyatt Place San Francisco Downtown

10/10 Excellent

"Room was clean and very convenient location. Nice staff."

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information)

![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg)

### Handlery Union Square Hotel

10/10 Excellent

"friendly staff and spacious rooms. only complaint is my bf (ex bf now) went through my phone during our stay and now are broken up but that has nothing to do with the hotel lol other than that i would 10/10 reccomend "

[](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information)

![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg)

### Holiday Inn Golden Gateway by IHG

10/10 Excellent

"Nice stay. Hotel was clean, quiet and accessible. "

[](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg)

### Fairmont San Francisco

10/10 Excellent

"YES!"

[](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information)

## Frequently asked questions

### What's it like in Downtown South San Francisco?

### What's a favorite place to stay in Downtown South San Francisco?

### How many hotels will I find in the Downtown South San Francisco area?

### If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

### What can I see and do in this South San Francisco neighborhood?

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- [Flights to San Francisco ](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)
- [Flights to South San Francisco ](https://www.expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights)
- [Flights from Los Angeles (LAX) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/lax/sfo/los-angeles-to-san-francisco)
- [Flights from Edmonton (YEG) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yeg/sfo/edmonton-to-san-francisco)
- [Flights from Montreal (YUL) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yul/sfo/montreal-to-san-francisco)
- [Flights from Vancouver (YVR) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco)
- [Flights from Calgary (YYC) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyc/sfo/calgary-to-san-francisco)
- [Flights from Toronto (YYZ) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco)

- [Visit Paradise Valley ](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811)
- [South San Francisco Vacations ](https://www.expedia.ca/South-San-Francisco.d6773.Destination-Travel-Guides)
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- [Rental cars San Francisco Intl. airport ](https://www.expedia.ca/Car-Rentals-In-San-Francisco-Intl.d5195347.Car-Rental-Guide)
- [Car rental South San Francisco ](https://www.expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide)
- [Enterprise Rental Cars in South San Francisco ](https://www.expedia.ca/Enterprise-Car-Rentals-In-South-San-Francisco.d6773-c15.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in South San Francisco ](https://www.expedia.ca/Hertz-Car-Rentals-In-South-San-Francisco.d6773-c40.Car-Rental-Guide-Suppliers)

- [South San Francisco Vacation Rentals ](https://www.expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals)

- [Things to do in South San Francisco ](https://www.expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities)

- [Book Hotels in Downtown South San Francisco on Expedia.com ](https://www.expedia.com/Downtown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels)