Title: 10 Best Hotels in Downtown South San Francisco, San Francisco for 2025 | Expedia.ca [Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Downtown South San Francisco Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-South-San-Francisco.d553248635976481411.Car-Rental-Guide)[Downtown South San Francisco Vacations](https://expedia.ca/Downtown-South-San-Francisco.d553248635976481411.Destination-Travel-Guides) ![Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015](https://images.trvl-media.com/place/553248635976481411/4dd74f8a-dfcd-4623-817e-767c96ff0c5c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Downtown South San Francisco, San Francisco ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Downtown South San Francisco Spa [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&amenities=SPA_ON_SITE) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&amenities=PETS) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&travelerType=family_friendly) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&lodging=COTTAGE) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&amenities=OCEAN_VIEW) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&lodging=APARTMENT) Condo [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&lodging=CONDO) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&amenities=HOT_TUB) Villa [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&lodging=VILLA) Pool [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&amenities=POOL) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Downtown+South+San+Francisco%2C+South+San+Francisco%2C+California%2C+United+States+of+America®ionId=553248635976481411&latLong=37.656785%2C-122.416446&adults=2&startDate=2025-10-28&d1=2025-10-28&endDate=2025-10-30&d2=2025-10-30&amenities=WATER_PARK) ## Check prices for these dates Tonight [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-10-14&endDate=2025-10-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-10-15&endDate=2025-10-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Downtown South San Francisco hotels and places to stay ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/4becccdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/3bdf7c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/6c7a44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Francisco Airport N Downtown South San Francisco 8.0/10 Very good (2019) "Great place to stay " CA $142 CA $167 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/779a738f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/dfaa473c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/466a0c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11980000/11974700/11974670/72b32b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Airport Inn Downtown South San Francisco 8.8/10 Excellent (965) "I was surprised by how friendly the front desk guy was when I checked in after midnight, and also by how clean the room was, for the price I would say this is unbeatable for the area, I will be back." CA $128 CA $151 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/aeecf8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/b9912bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/5e691720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1140000/1139300/1139289/9b3dc53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn By The SFO Downtown South San Francisco 7.8/10 Good (1000) "Excellent property!!! I would definitely recommend!!! Great stay!!! " CA $124 CA $146 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information) ![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/48a324c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/1e2e26cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/60ad2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, dining tables](https://images.trvl-media.com/lodging/92000000/91120000/91116900/91116819/a007dfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Miller Apartments Downtown South San Francisco 7.8/10 Good (14) "Ty" CA $88 CA $209 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/San-Francisco-Hotels-Miller-Apartments.h91116819.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/b406d764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/927fa680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/7d66de20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/578900/578899/w5614h3742x0y0-0021dd27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express and Suites Fisherman's Wharf by IHG 16.6 km from Downtown South San Francisco 9.0/10 Wonderful (2173) "Had a wonderful stay, staff was wonderful." CA $194 CA $270 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/San-Francisco-Hotels-Holiday-Inn-Express-And-Suites-Fishermans-Wharf.h578899.Hotel-Information) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/b2c792a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/6f39558c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/c6353244.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1040000/1038100/1038086/f593cfd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor View Inn 17.7 km from Downtown South San Francisco 9.0/10 Wonderful (587) "This is a good well kept motel. The rooms are a good value. I would stay here again. " CA $190 CA $223 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Half-Moon-Bay-Hotels-Harbor-View-Inn.h1038086.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/a6d4d3b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/a4d83df4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/7e38cd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/2000000/1160000/1154600/1154559/e2af1c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel North Beach 15.6 km from Downtown South San Francisco 7.0/10 Good (1000) "Shops great food cool vibe this the coolest place love it " CA $77 CA $90 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-North-Beach.h1154559.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/9f22ad54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Loft, 1 Bedroom, Balcony, Golf View](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/1d228ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/a404f6d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/20000/11700/11624/0992f574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Half Moon Bay Lodge 24.9 km from Downtown South San Francisco 9.0/10 Wonderful (1013) "Definitely would stay there again. Felt like being with family." CA $196 CA $230 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Half-Moon-Bay-Hotels-Half-Moon-Bay-Lodge.h11624.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/9b58109d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/ace9cc04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/22520ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Centric Fisherman's Wharf San Francisco 16.6 km from Downtown South San Francisco 8.6/10 Excellent (1440) "Great place to stay." CA $190 CA $281 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/3fd8b468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/c37460ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/ac2abcd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Caza Fisherman's Wharf 16.7 km from Downtown South San Francisco 9.0/10 Wonderful (3822) "very nice place to stay" CA $181 CA $277 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/818bb89d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Room](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/d9813769.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/9dd6fb90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/7ed3ce17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### FOUND Hotel Carlton, Nob Hill 14.6 km from Downtown South San Francisco 8.6/10 Excellent (953) "Place is amazing " CA $95 CA $112 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Francisco-Hotels-FOUND-Hotel-San-Francisco-Carlton.h103126565.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/b020c7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/2aabc067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/75f20517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Fisherman's Wharf 16.7 km from Downtown South San Francisco 9.0/10 Wonderful (7001) "Excellent breakfast and great on site parking" CA $185 CA $276 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16000/15933/51c27ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/16000/15933/d89ed5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/1000000/20000/16000/15933/870edba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/16000/15933/21861201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Majestic 14.5 km from Downtown South San Francisco 9.2/10 Wonderful (1021) "I love how close the hotel is to Japan Town, this is our second time staying there and will be back for a third stay in the near future!" CA $170 CA $198 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Majestic.h15933.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/2392a014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/91c59b83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/fc8303ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/60300/60226/a752a104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Tiburon 24.5 km from Downtown South San Francisco 8.8/10 Excellent (1010) "Fun happy hour and nice pool area as well as surrounding area." CA $279 CA $353 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Tiburon-Hotels-The-Lodge-At-Tiburon.h60226.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/095a2e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/5beb890e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/b0813be9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/60000/51200/51116/b9e253e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marina Inn on San Francisco Bay 20.6 km from Downtown South San Francisco 8.6/10 Excellent (2158) "Such a great place to stay! Wonderful staff! " CA $133 CA $152 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/Oakland-Hotels-The-Marina-Inn-On-San-Francisco-Bay.h51116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/7b888e27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/4e19d797.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/ccdc9b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26500/26500/5b453bab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco Airport 8.4 km from Downtown South San Francisco 8.8/10 Excellent (1335) "beautifull place" CA $190 CA $256 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco-Airport.h26500.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6c2cdc12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/3daecce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed, Accessible](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/w1781h1201x19y0-3696f576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/ba21aee0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Nikko San Francisco 14.3 km from Downtown South San Francisco 9.4/10 Exceptional (2584) "Everything from the staff to the location was excellent. Will definitely stay here again." CA $273 CA $386 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3836h2556x4y4-feec9994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Bay View](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3837h2557x3y3-515ac187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3837h2557x3y3-420d1afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/550000/548000/547988/w3836h2557x4y3-eea62304.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HYATT house Emeryville/San Francisco Bay Area 23 km from Downtown South San Francisco 9.0/10 Wonderful (1149) "Great stay " CA $213 CA $239 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Oakland-Hotels-HYATT-House-EmeryvilleSan-Francisco-Bay-Area.h547988.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/fee85a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/w3494h1969x0y0-d84c81ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/767c7710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/5800/5798/b1137dc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SFO El Rancho Inn SureStay Collection by Best Western 5.7 km from Downtown South San Francisco 8.4/10 Very good (2888) "Ideal for a stopover night." CA $166 CA $192 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Francisco-Hotels-SFO-Airport-Hotel.h5798.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool, open 8 AM to 8 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/4fd95a3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/18d49d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/63a5d8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Handlery Union Square Hotel 14.5 km from Downtown South San Francisco 8.8/10 Excellent (2768) "very nice stay" CA $192 CA $226 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30®ionId=553248635976481411&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDowntown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDowntown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels) ## Where to stay in Downtown South San Francisco Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. - Union Square - Fisherman's Wharf - Downtown San Francisco - South of Market - Nob Hill ![Union Square featuring a city and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22611-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square featuring a city, street scenes and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173736-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square featuring a city, a monument and a square or plaza](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173470-Northern-California.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square showing street scenes and a city as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/67000/67250-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Union Square showing street scenes, a city and signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173732-Union-Square.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=800129) ![Union Square map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:owseFngdjV_H%7BeAzRuBna%40%7Ej%40qPdCn%40pIwDv%40n%40tGaXjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=vbtXVjtvbbFJoglIicZiXTBOs3E=) ### Union Square Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems. [See properties](https://www.expedia.ca/Hotel-Search?regionId=800129) ![Fisherman\'s Wharf featuring a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240986-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/548000/548532-fishermans-wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Fisherman\'s Wharf which includes a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173418-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Fisherman\'s Wharf which includes a fountain](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240993-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173428-Fishermans-Wharf.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=800128) ![Fisherman's Wharf map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mrweFnpfjVaIcEiDic%40wAal%40xF_c%40bZoH%60N%7CwBeMnBaIpEsF%7E%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=cSLnJ-bErQxSUv6GQKloGDHAW70=) ### Fisherman's Wharf Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access. [See properties](https://www.expedia.ca/Hotel-Search?regionId=800128) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476363-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476367-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476362-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476359-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476366-Downtown-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6151902) ![Downtown San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:m%7EteFvzejViZadFhsAmj%40%60lBaHdLhWlEviCoQtFoGdcByHdFwR%7BUc%60ChY&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=gvmSEImu4_lfi0gTpvxWcEmihx8=) ### Downtown San Francisco Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6151902) ![South of Market showing skyline, a city and city views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173326-San-Francisco.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market showing a fountain, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173924-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market featuring a city, a skyscraper and central business district](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173938-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market featuring skyline, city views and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173935-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![South of Market featuring city views and a city as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173937-South-Of-Market.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=160166) ![South of Market map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eipeF%7CxejVcaDsjEjv%40gt%40ffCuYvGdhDsKvBsD%7CF%7DBz%5BoCx%7C%40_E%7EGqC%7EA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ffiqKO1x2yhUpPKU2D52Jx63lg4=) ### South of Market From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods. [See properties](https://www.expedia.ca/Hotel-Search?regionId=160166) ![Nob Hill featuring street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173402-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill which includes street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173400-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173393-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173395-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Nob Hill featuring street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/173000/173391-Nob-Hill.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=138629) ![Nob Hill map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:q%7EteFvxejVmIopAll%40cHnIppAol%40%60H&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Skcsr6ZgxKZlWMjutOt189xwFug=) ### Nob Hill Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history. [See properties](https://www.expedia.ca/Hotel-Search?regionId=138629) ## Top Downtown South San Francisco Hotel Reviews ![DoubleTree by Hilton Hotel Berkeley Marina](//images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "I love the clean, comfy beds and linens, the outdoor fireplace on the patio, the warm cookies, the tranquil atmosphere and the location on the water. The staff are friendly and supportive, offering smiles and warm choc chip cookies! I especially appreciated thier efforts to assist me when I needed to correct a date error in my reservation. All in all I love the hotel and always stay there when in the Bay Area. " [](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Club Quarters Hotel in San Francisco](//images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "Great location clean room super nice staff ☺️" [](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Hotel Riu Plaza Fisherman's Wharf](//images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Breakfast was great for us with alot of choice . We found the location excellent. We actually walked to the cruise ship port rather than Uber because it was so close ! " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Claremont Resort & Club](//images.trvl-media.com/lodging/1000000/10000/6700/6609/d997dca7_y.jpg) ### Claremont Resort & Club 10/10 Excellent "Beautiful, classic property. Great art and views." [](https://expedia.ca/Oakland-Hotels-Claremont-Club-Spa-A-Fairmont-Hotel.h6609.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](//images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "Clean room, great staff and amazing location. " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Chancellor Hotel on Union Square](//images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "The room was clean and adequate for our needs - small, but fine. Location was close to shops. Friendly, helpful staff. Cute boutique hotel!" [](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Crowne Plaza San Francisco Airport by IHG](//images.trvl-media.com/lodging/1000000/30000/28600/28502/336a0345_y.jpg) ### Crowne Plaza San Francisco Airport by IHG 10/10 Excellent "Everything was perfect " [](https://expedia.ca/San-Francisco-Hotels-Crowne-Plaza-San-Francisco-Airport.h28502.Hotel-Information) ![Hilton San Francisco Financial District](//images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Great location! Bar needs to be restocked " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![Handlery Union Square Hotel](//images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "The staff was very helpful and the room was kept very clean. Just a note the pool is not suitable for lap swimming but great for lounging. I would recommend that the hotel put in a small motion sensitive light in the bathroom. Those 2 things aside I enjoyed my stay." [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ## Frequently asked questions ### What's it like in Downtown South San Francisco? > You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood. ### What's a favorite place to stay in Downtown South San Francisco? > Based on Expedia customer reviews, [La Quinta Inn & Suites by Wyndham San Francisco Airport N](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information) is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include [Airport Inn](https://www.expedia.ca/San-Francisco-Hotels-Airport-Inn.h11974670.Hotel-Information) and [Inn By The SFO](https://www.expedia.ca/San-Francisco-Hotels-Inn-By-The-SFO.h1139289.Hotel-Information). ### How many hotels will I find in the Downtown South San Francisco area? > When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco. ### If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund? > Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco. ### What can I see and do in this South San Francisco neighborhood? > See's Candies, Cinemark Century at Tanforan, and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Paradise Valley](https://www.expedia.ca/1Star-Paradise-Valley-San-Francisco-Hotels.s10-n553248635976473811-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Oyster Point](https://www.expedia.ca/5Star-Oyster-Point-San-Francisco-Hotels.s50-n553248635976007474-0.Travel-Guide-Filter-Hotels) - [Avalon Hotels](https://www.expedia.ca/Avalon-San-Francisco-Hotels.0-n553248635976479280-0.Travel-Guide-Filter-Hotels) - [Hotels near Bayfront Park](https://www.expedia.ca/Bayfront-Park-Hotels.0-l553248621579088854-0.Travel-Guide-Filter-Hotels) - [Bayshore Heights Hotels](https://www.expedia.ca/Bayshore-Heights-San-Francisco-Hotels.0-n553248635976471419-0.Travel-Guide-Filter-Hotels) - [Brisbane Hotels](https://www.expedia.ca/Brisbane-Hotels.d602634.Travel-Guide-Hotels) - [Colma Hotels](https://www.expedia.ca/Colma-San-Francisco-Hotels.0-n553248635077778701-0.Travel-Guide-Filter-Hotels) - [Hotels near Colma Station](https://www.expedia.ca/Colma-Station-Hotels.d6176489.Travel-Guide-Hotels) - [Hotels near Cow Palace](https://www.expedia.ca/Cow-Palace-Hotels.0-l502571-0.Travel-Guide-Filter-Hotels) - [Hotels near Cypress Lawn Memorial Park](https://www.expedia.ca/Cypress-Lawn-Memorial-Park-Hotels.0-l553248621532640149-0.Travel-Guide-Filter-Hotels) - [Daly City Hotels](https://www.expedia.ca/Daly-City-Hotels.d6764.Travel-Guide-Hotels) - [Downtown Brisbane Hotels](https://www.expedia.ca/Downtown-Brisbane-San-Francisco-Hotels.0-n553248635976472493-0.Travel-Guide-Filter-Hotels) - [Millbrae Hotels](https://www.expedia.ca/Millbrae-Hotels.d8631.Travel-Guide-Hotels) - [Hotels near Millbrae Station](https://www.expedia.ca/Millbrae-Station-Hotels.d6176502.Travel-Guide-Hotels) - [All Inclusive Resorts and in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-All-Inclusive-Hotel.0-n553248635976007474-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Beach-Hotel.0-n553248635976007474-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Cheap-Hotels.0-n553248635976007474-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Family-Hotel.0-n553248635976007474-0-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Hotels-With-Bar.0-n553248635976007474-0-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Hotels-With-Indoor-Pool.0-n553248635976007474-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Luxury-Hotel.0-n553248635976007474-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Oceanfront-Hotels.0-n553248635976007474-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Pet-Friendly-Hotel.0-n553248635976007474-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Romantic-Hotel.0-n553248635976007474-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Shopping Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Shopping-Hotel.0-n553248635976007474-0-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Oyster Point](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels-Ski-Hotel.0-n553248635976007474-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Oyster Point Hotels](https://www.expedia.ca/Oyster-Point-San-Francisco-Hotels.0-n553248635976007474-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Paradise Valley](https://www.expedia.ca/Paradise-Valley-San-Francisco-Hotels-Boutique-Hotel.0-n553248635976473811-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Paradise Valley](https://www.expedia.ca/Paradise-Valley-San-Francisco-Hotels-Hotels-With-Free-Breakfast.0-n553248635976473811-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Paradise Valley](https://www.expedia.ca/Paradise-Valley-San-Francisco-Hotels-Hotels-With-Indoor-Pool.0-n553248635976473811-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Paradise Valley](https://www.expedia.ca/Paradise-Valley-San-Francisco-Hotels-Mountain-Hotels.0-n553248635976473811-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Paradise Valley Hotels](https://www.expedia.ca/Paradise-Valley-San-Francisco-Hotels.0-n553248635976473811-0.Travel-Guide-Filter-Hotels) - [San Bruno Hotels](https://www.expedia.ca/San-Bruno-Hotels.d6633.Travel-Guide-Hotels) - [Hotels near San Bruno Station](https://www.expedia.ca/San-Bruno-Station-Hotels.d6176493.Travel-Guide-Hotels) - [Hotels near San Bruno Station](https://www.expedia.ca/San-Bruno-Station-Hotels.d6176542.Travel-Guide-Hotels) - [Hotels near San Francisco Baking Institute](https://www.expedia.ca/San-Francisco-Baking-Institute-Hotels.0-l553248635125895275-0.Travel-Guide-Filter-Hotels) - [San Francisco Hotels](https://www.expedia.ca/San-Francisco-Hotels.d178305.Travel-Guide-Hotels) - [Hotels near San Francisco Intl.](https://www.expedia.ca/San-Francisco-Intl-Airport-Hotels.0-aSFO-0.Travel-Guide-Filter-Hotels) - [Hotels near San Francisco Intl. Airport Station](https://www.expedia.ca/San-Francisco-Intl-Airport-Station-Hotels.d6176497.Travel-Guide-Hotels) - [Hotels near Serramonte Center](https://www.expedia.ca/Serramonte-Center-Hotels.0-l6151604-0.Travel-Guide-Filter-Hotels) - [B&B in South San Francisco](https://www.expedia.ca/South-San-Francisco-Bed-And-Breakfast.d6773-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near South San Francisco Convention Center](https://www.expedia.ca/South-San-Francisco-Convention-Center-Hotels.0-l6131179-0.Travel-Guide-Filter-Hotels) - [Hostels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hostels.d6773-aaHostels.Travel-Guide-Accommodation) - [Accor Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Accor-Hotels.0-0-d6773--bAccorHotels.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-All-Inclusive-Hotel.0-0-d6773-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Beach-Hotel.0-0-d6773-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Boutique-Hotel.0-0-d6773-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Cheap-Hotels.0-0-d6773-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Couples-Resorts-Hotels.0-0-d6773-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Family-Hotel.0-0-d6773-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Historic-Hotel.0-0-d6773-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotel-With-Early-Check-In.0-0-d6773-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Bar in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Bar.0-0-d6773-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d6773-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Free-Breakfast.0-0-d6773-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Free-Parking.0-0-d6773-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Hot-Tubs.0-0-d6773-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Kitchenettes.0-0-d6773-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-LGBT-Friendly-Hotel.0-0-d6773-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Luxury-Hotel.0-0-d6773-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Mountain-Hotels.0-0-d6773-tMountainHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Oceanfront-Hotels.0-0-d6773-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Pet-Friendly-Hotel.0-0-d6773-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Shopping Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Shopping-Hotel.0-0-d6773-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Spa-Hotel.0-0-d6773-tSpaHotel.Travel-Guide-Filter-Hotels) - [Winery Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Winery-Hotel.0-0-d6773-tWineryHotel.Travel-Guide-Filter-Hotels) - [South San Francisco Hotels](https://www.expedia.ca/South-San-Francisco-Hotels.d6773.Travel-Guide-Hotels) - [Houseboats in South San Francisco](https://www.expedia.ca/South-San-Francisco-Houseboats.d6773-aaHouseboats.Travel-Guide-Accommodation) - [Inns in South San Francisco](https://www.expedia.ca/South-San-Francisco-Inns.d6773-aaInns.Travel-Guide-Accommodation) - [Hotels near South San Francisco Metro Station](https://www.expedia.ca/South-San-Francisco-Metro-Station-Hotels.d6176491.Travel-Guide-Hotels) - [Motels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Motels.d6773-aaMotels.Travel-Guide-Accommodation) - [Resorts in South San Francisco](https://www.expedia.ca/South-San-Francisco-Resort-Hotels.d6773-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in South San Francisco Station](https://www.expedia.ca/South-San-Francisco-Station-Apart-Hotels.d6173603-aaApartHotels.Travel-Guide-Accommodation) - [B&B in South San Francisco Station](https://www.expedia.ca/South-San-Francisco-Station-Bed-And-Breakfast.d6173603-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near South San Francisco Station](https://www.expedia.ca/South-San-Francisco-Station-Hotels.d6173603.Travel-Guide-Hotels) - [Townhomes in South San Francisco](https://www.expedia.ca/South-San-Francisco-Townhomes.d6773-aaTownhomes.Travel-Guide-Accommodation) - [Sunshine Gardens Hotels](https://www.expedia.ca/Sunshine-Gardens-San-Francisco-Hotels.0-n553248635976470279-0.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in The East Side](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels-Hotels-With-Free-Airport-Shuttle.0-n553248635976472836-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in The East Side](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels-Hotels-With-Free-Breakfast.0-n553248635976472836-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Romantic Hotels in The East Side](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels-Romantic-Hotel.0-n553248635976472836-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [The East Side Hotels](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels.0-n553248635976472836-0.Travel-Guide-Filter-Hotels) - [Hotels near The Shops at Tanforan](https://www.expedia.ca/The-Shops-At-Tanforan-Hotels.0-l6161254-0.Travel-Guide-Filter-Hotels) - [Visitacion Valley Hotels](https://www.expedia.ca/Visitacion-Valley-San-Francisco-Hotels.0-n553248635976480925-0.Travel-Guide-Filter-Hotels) - [Flights to San Francisco](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights) - [Flights to South San Francisco](https://www.expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights) - [Flights from Los Angeles (LAX) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/lax/sfo/los-angeles-to-san-francisco) - [Flights from Edmonton (YEG) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yeg/sfo/edmonton-to-san-francisco) - [Flights from Montreal (YUL) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yul/sfo/montreal-to-san-francisco) - [Flights from Vancouver (YVR) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco) - [Flights from Calgary (YYC) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyc/sfo/calgary-to-san-francisco) - [Flights from Toronto (YYZ) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco) - [Visit Paradise Valley](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811) - [South San Francisco Vacations](https://www.expedia.ca/South-San-Francisco.d6773.Destination-Travel-Guides) - [Visit South San Francisco](https://www.expedia.ca/South-San-Francisco.dx6773) - [Rental cars San Francisco Intl. airport](https://www.expedia.ca/Car-Rentals-In-San-Francisco-Intl.d5195347.Car-Rental-Guide) - [Car rental South San Francisco](https://www.expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide) - [Enterprise Rental Cars in South San Francisco](https://www.expedia.ca/Enterprise-Car-Rentals-In-South-San-Francisco.d6773-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in South San Francisco](https://www.expedia.ca/Hertz-Car-Rentals-In-South-San-Francisco.d6773-c40.Car-Rental-Guide-Suppliers) - [South San Francisco Vacation Rentals](https://www.expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals) - [Things to do in South San Francisco](https://www.expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities) - [Book Hotels in Downtown South San Francisco on Expedia.com](https://www.expedia.com/Downtown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels) - Explore a world of travel with Expedia ### Hotels in top San Francisco neighborhoods - [Hotels in Union Square](https://expedia.ca/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Hotels in Fisherman's Wharf](https://expedia.ca/Fishermans-Wharf-San-Francisco-Hotels.0-n800128-0.Travel-Guide-Filter-Hotels) - [Hotels in Downtown San Francisco](https://expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels.0-n6151902-0.Travel-Guide-Filter-Hotels) - [Hotels in South of Market](https://expedia.ca/South-Of-Market-San-Francisco-Hotels.0-n160166-0.Travel-Guide-Filter-Hotels) - [Hotels in Nob Hill](https://expedia.ca/Nob-Hill-San-Francisco-Hotels.0-n138629-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission District](https://expedia.ca/Mission-District-San-Francisco-Hotels.0-n134035-0.Travel-Guide-Filter-Hotels) - [Hotels in Financial District](https://expedia.ca/Financial-District-San-Francisco-Hotels.0-n6056710-0.Travel-Guide-Filter-Hotels) - [Hotels in Russian Hill](https://expedia.ca/Russian-Hill-San-Francisco-Hotels.0-n553248621561137041-0.Travel-Guide-Filter-Hotels) - [Hotels in North Beach](https://expedia.ca/North-Beach-San-Francisco-Hotels.0-n138972-0.Travel-Guide-Filter-Hotels) - [Hotels in Golden Gate](https://expedia.ca/Golden-Gate-San-Francisco-Hotels.0-n553248635976481407-0.Travel-Guide-Filter-Hotels) - [Hotels in Marina District](https://expedia.ca/Marina-District-San-Francisco-Hotels.0-n130032-0.Travel-Guide-Filter-Hotels) - [Hotels in Western Addition](https://expedia.ca/Western-Addition-San-Francisco-Hotels.0-n173536-0.Travel-Guide-Filter-Hotels) - [Hotels in Pacific Heights](https://expedia.ca/Pacific-Heights-San-Francisco-Hotels.0-n142901-0.Travel-Guide-Filter-Hotels) - [Hotels in Chinatown](https://expedia.ca/Chinatown-San-Francisco-Hotels.0-n6004910-0.Travel-Guide-Filter-Hotels) - [Hotels in Sunset District](https://expedia.ca/Sunset-District-San-Francisco-Hotels.0-n163838-0.Travel-Guide-Filter-Hotels) - [Hotels in Cow Hollow](https://expedia.ca/Cow-Hollow-San-Francisco-Hotels.0-n6155698-0.Travel-Guide-Filter-Hotels) - [Hotels in Noe Valley](https://expedia.ca/Noe-Valley-San-Francisco-Hotels.0-n6155705-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission Bay](https://expedia.ca/Mission-Bay-San-Francisco-Hotels.0-n553248635976008622-0.Travel-Guide-Filter-Hotels) - [Hotels in Potrero Hill](https://expedia.ca/Potrero-Hill-San-Francisco-Hotels.0-n506137-0.Travel-Guide-Filter-Hotels) - [Hotels in Excelsior](https://expedia.ca/Excelsior-San-Francisco-Hotels.0-n553248635976470979-0.Travel-Guide-Filter-Hotels) ### Hotels near popular San Francisco Attractions - [Hotels near Silicon Valley](https://expedia.ca/Silicon-Valley-Hotels.0-l6023769-0.Travel-Guide-Filter-Hotels) - [Hotels near Golden Gate Park](https://expedia.ca/Golden-Gate-Park-Hotels.0-l507464-0.Travel-Guide-Filter-Hotels) - [Hotels near Pier 39](https://expedia.ca/Pier-39-Hotels.0-l502576-0.Travel-Guide-Filter-Hotels) - [Hotels near Golden Gate Bridge](https://expedia.ca/Golden-Gate-Bridge-Hotels.0-l508803-0.Travel-Guide-Filter-Hotels) - [Hotels near Oracle Park](https://expedia.ca/Oracle-Park-Hotels.0-l6063199-0.Travel-Guide-Filter-Hotels) - [Hotels near Chase Center](https://expedia.ca/Chase-Center-Hotels.0-l553248635997928290-0.Travel-Guide-Filter-Hotels) - [Hotels near Moscone Convention Center](https://expedia.ca/Moscone-Convention-Center-Hotels.0-l502553-0.Travel-Guide-Filter-Hotels) - [Hotels near San Francisco Bay](https://expedia.ca/San-Francisco-Bay-Hotels.0-l6203208-0.Travel-Guide-Filter-Hotels) - [Hotels near Alcatraz Island](https://expedia.ca/Alcatraz-Island-Hotels.0-l502554-0.Travel-Guide-Filter-Hotels) - [Hotels near Presidio of San Francisco](https://expedia.ca/Presidio-Of-San-Francisco-Hotels.0-l502558-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Downtown South San Francisco - [Apartments in San Francisco](https://expedia.ca/San-Francisco-Apartments.d178305-aaApartments.Travel-Guide-Accommodation) - [Vacation Homes in San Francisco](https://expedia.ca/San-Francisco-Private-Vacation-Homes.d178305-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Condo Rentals in San Francisco](https://expedia.ca/San-Francisco-Condos.d178305-aaCondos.Travel-Guide-Accommodation) - [Motels in San Francisco](https://expedia.ca/San-Francisco-Motels.d178305-aaMotels.Travel-Guide-Accommodation) - [Guest Houses in San Francisco](https://expedia.ca/San-Francisco-Guest-Houses.d178305-aaGuestHouses.Travel-Guide-Accommodation) - [Aparthotels in San Francisco](https://expedia.ca/San-Francisco-Apart-Hotels.d178305-aaApartHotels.Travel-Guide-Accommodation) - [Cottages in San Francisco](https://expedia.ca/San-Francisco-Cottages.d178305-aaCottages.Travel-Guide-Accommodation) - [B&B in San Francisco](https://expedia.ca/San-Francisco-Bed-And-Breakfast.d178305-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hostels in San Francisco](https://expedia.ca/San-Francisco-Hostels.d178305-aaHostels.Travel-Guide-Accommodation) - [Resorts in San Francisco](https://expedia.ca/San-Francisco-Resort-Hotels.d178305-aaResortHotels.Travel-Guide-Accommodation) - [Inns in San Francisco](https://expedia.ca/San-Francisco-Inns.d178305-aaInns.Travel-Guide-Accommodation) - [Cabin Rentals in San Francisco](https://expedia.ca/San-Francisco-Cabins.d178305-aaCabins.Travel-Guide-Accommodation) - [Lodges in San Francisco](https://expedia.ca/San-Francisco-Lodges.d178305-aaLodges.Travel-Guide-Accommodation) - [Villas in San Francisco](https://expedia.ca/San-Francisco-Villas.d178305-aaVillas.Travel-Guide-Accommodation) - [Capsule Hotels in San Francisco](https://expedia.ca/San-Francisco-Capsule-Hotels.d178305-aaCapsuleHotels.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near San Francisco Intl. Airport](https://expedia.ca/San-Francisco-Intl-Airport-Hotels.0-aSFO-0.Travel-Guide-Filter-Hotels) - [Hotels near Oakland Intl. Airport](https://expedia.ca/Oakland-Intl-Airport-Hotels.0-aOAK-0.Travel-Guide-Filter-Hotels) - [Hotels near Oakland Convention Center Heliport Airport](https://expedia.ca/Oakland-Convention-Center-Heliport-Airport-Hotels.0-aJCE-0.Travel-Guide-Filter-Hotels) - [Hotels near Hayward Executive Airport](https://expedia.ca/Hayward-Executive-Airport-Hotels.0-aHWD-0.Travel-Guide-Filter-Hotels) - [Hotels near Santa Clara County Airport](https://expedia.ca/Santa-Clara-County-Airport-Hotels.0-aPAO-0.Travel-Guide-Filter-Hotels) - [Hotels near San Rafael Airport](https://expedia.ca/San-Rafael-Airport-Hotels.0-aSRF-0.Travel-Guide-Filter-Hotels) ### Downtown South San Francisco Hotels by Star Rating - [2 Star Hotels in Downtown South San Francisco](https://expedia.ca/2Star-Downtown-South-San-Francisco-San-Francisco-Hotels.s20-n553248635976481411-0.Travel-Guide-Filter-Hotels) ### Downtown South San Francisco Hotels by Brand - [Hilton Hotels Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-Hilton-Hotels.0-n553248635976481411-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hostelling International Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-Hostelling-International.0-n553248635976481411-0--bHostellingInternational.Travel-Guide-Filter-Hotels) - [Independent Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-Independent.0-n553248635976481411-0--bIndependent.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n553248635976481411-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-Marriott-Hotels-Resorts.0-n553248635976481411-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Sonesta Hotel Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-Sonesta-Hotel.0-n553248635976481411-0--bSonestaHotel.Travel-Guide-Filter-Hotels) - [Vagabond Inn Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-Vagabond-Inn.0-n553248635976481411-0--bVagabondInn.Travel-Guide-Filter-Hotels) - [Wyndham Extra Holidays Hotels](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels-Wyndham-Extra-Holidays.0-n553248635976481411-0--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Hyatt Regency San Francisco Downtown SOMA](https://expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information) - [Hotel Caza Fisherman's Wharf](https://expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) - [Hyatt Centric Fisherman's Wharf San Francisco](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) - [Handlery Union Square Hotel](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) - [Chancellor Hotel on Union Square](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) - [The Pickwick Hotel](https://expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) - [Bay Landing San Francisco Airport Hotel](https://expedia.ca/San-Francisco-Hotels-Bay-Landing-San-Francisco-Airport-Hotel.h1110785.Hotel-Information) - [FOUND Hotel Carlton, Nob Hill](https://expedia.ca/San-Francisco-Hotels-FOUND-Hotel-San-Francisco-Carlton.h103126565.Hotel-Information) - [Comfort Inn by the Bay](https://expedia.ca/San-Francisco-Hotels-Comfort-Inn-By-The-Bay.h5984.Hotel-Information) - [Taj Campton Place](https://expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) - [InterContinental San Francisco by IHG](https://expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) - [The Marina Inn on San Francisco Bay](https://expedia.ca/Oakland-Hotels-The-Marina-Inn-On-San-Francisco-Bay.h51116.Hotel-Information) [See a list of all hotels in San Francisco](https://expedia.ca/All-San-Francisco-Hotels.d178305.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Downtown South San Francisco on Expedia.com](https://www.expedia.com/Downtown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels) ### Expedia's Latest Trends Hotels - [Union Square hotels](https://expedia.ca/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Hotels near Chase Center](https://expedia.ca/Chase-Center-Hotels.0-l553248635997928290-0.Travel-Guide-Filter-Hotels) - [Hotels near Pier 39](https://expedia.ca/Pier-39-Hotels.0-l502576-0.Travel-Guide-Filter-Hotels) - [Downtown San Francisco hotels](https://expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels.0-n6151902-0.Travel-Guide-Filter-Hotels) - [Hotels near Oracle Park](https://expedia.ca/Oracle-Park-Hotels.0-l6063199-0.Travel-Guide-Filter-Hotels) - [Japantown hotels](https://expedia.ca/Japantown-San-Francisco-Hotels.0-n6151730-0.Travel-Guide-Filter-Hotels) - [Nob Hill hotels](https://expedia.ca/Nob-Hill-San-Francisco-Hotels.0-n138629-0.Travel-Guide-Filter-Hotels) - [Haight-Ashbury hotels](https://expedia.ca/Haight-Ashbury-San-Francisco-Hotels.0-n111752-0.Travel-Guide-Filter-Hotels) - [Mission District hotels](https://expedia.ca/Mission-District-San-Francisco-Hotels.0-n134035-0.Travel-Guide-Filter-Hotels) - [Fisherman's Wharf hotels](https://expedia.ca/Fishermans-Wharf-San-Francisco-Hotels.0-n800128-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Union Square](https://expedia.ca/Union-Square-San-Francisco-Hotels-Boutique-Hotel.0-n800129-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [North Beach hotels](https://expedia.ca/North-Beach-San-Francisco-Hotels.0-n138972-0.Travel-Guide-Filter-Hotels) - [Hotels near Moscone Convention Center](https://expedia.ca/Moscone-Convention-Center-Hotels.0-l502553-0.Travel-Guide-Filter-Hotels) Cars - [Car rentals in Fisherman's Wharf](https://expedia.ca/Car-Rentals-In-Fishermans-Wharf.d800128.Car-Rental-Guide) - [Car rentals in Downtown San Francisco](https://expedia.ca/Car-Rentals-In-Downtown-San-Francisco.d6151902.Car-Rental-Guide) Packages - [Pier 39](https://expedia.ca/Pier-39-Fishermans-Wharf.d502576.Vacation-Attraction) - [Presidio of San Francisco](https://expedia.ca/Presidio-Of-San-Francisco-Presidio.d502558.Vacation-Attraction) - [Palace of Fine Arts](https://expedia.ca/Palace-Of-Fine-Arts-Marina-District.d502564.Vacation-Attraction) - [Lombard Street](https://expedia.ca/Lombard-Street-Russian-Hill.d502557.Vacation-Attraction) - [De Young Museum](https://expedia.ca/De-Young-Museum-Golden-Gate.d6063203.Vacation-Attraction) - [California Academy of Sciences](https://expedia.ca/California-Academy-Of-Sciences-Golden-Gate.d6151535.Vacation-Attraction) - [Grace Cathedral](https://expedia.ca/Grace-Cathedral-Downtown-San-Francisco.d6069413.Vacation-Attraction) - [Oracle Park](https://expedia.ca/Oracle-Park-Downtown-San-Francisco.d6063199.Vacation-Attraction) General - [Visit Pacific Heights](https://expedia.ca/San-Francisco-Pacific-Heights.dx142901) - [Visit Nob Hill](https://expedia.ca/San-Francisco-Nob-Hill.dx138629) - [Visit Fisherman's Wharf](https://expedia.ca/San-Francisco-Fishermans-Wharf.dx800128) - [Visit Downtown San Francisco](https://expedia.ca/San-Francisco-Downtown-San-Francisco.dx6151902) - [Visit Union Square](https://expedia.ca/San-Francisco-Union-Square.dx800129) - [Visit Marina District](https://expedia.ca/San-Francisco-Marina-District.dx130032) - [Visit Haight-Ashbury](https://expedia.ca/San-Francisco-Haight-Ashbury.dx111752)