Title: Hotels by Highgate Independent in Downtown San Francisco from CA $325 | Expedia.ca [Downtown San Francisco Travel Guide](https://expedia.ca/San-Francisco-Downtown-San-Francisco.dx6151902)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Downtown San Francisco Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-San-Francisco.d6151902.Car-Rental-Guide)[Downtown San Francisco Vacations](https://expedia.ca/Downtown-San-Francisco.d6151902.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476363-Downtown-San-Francisco.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Highgate Independent in Downtown San Francisco from CA $325 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=6151902&startDate=2025-09-24&endDate=2025-09-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=6151902&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6151902&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6151902&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Downtown San Francisco Highgate Independent Hotels ## Our top choices for Downtown San Francisco Highgate Independent ![Skyline Studio, 2 Double Beds | City view](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/8ee09bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/97b02c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/fdd98ab4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Skyline Studio, 2 Double Beds | Interior](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/cf628776.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stanford Court San Francisco Downtown San Francisco 9.0/10 Wonderful (1330) "Love this Hotel!" CA $223 CA $325 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Francisco-Hotels-Stanford-Court-San-Francisco.h6271901.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/900/864/f1cd732e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/864/d0a3a9da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/10000/900/864/ad4b22ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/900/864/ea6e7ac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Huntington Hotel Downtown San Francisco 9.2/10 Wonderful (1000) [](https://www.expedia.ca/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=6151902&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDowntown-San-Francisco-San-Francisco-Hotels-Highgate-Independent.0-n6151902-0--bHighgateIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDowntown-San-Francisco-San-Francisco-Hotels-Highgate-Independent.0-n6151902-0--bHighgateIndependent.Travel-Guide-Filter-Hotels) ## Top Downtown San Francisco Hotel Reviews ![Handlery Union Square Hotel](//images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Clean room, excellent staff, " [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](//images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "Clean room nice staff great views of the city best hotel i’ve ever stayed at " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Soma House](//images.trvl-media.com/lodging/97000000/96820000/96812500/96812469/e93fae2b_y.jpg) ### Soma House 10/10 Excellent "The room was so clean and you can tell it's been renovated. The staff was so friendly and made our stay so helpful accommodation some of my mom's requests. While the hotel itself is so nice, the area around it is still a little rough. Not a spot I'd recommend walking back to late at night if you're unfamiliar with the city/by yourself." [](https://expedia.ca/San-Francisco-Hotels-Soma-House.h96812469.Hotel-Information) ![Hotel Nikko San Francisco](//images.trvl-media.com/lodging/1000000/30000/23500/23406/6c2cdc12_y.jpg) ### Hotel Nikko San Francisco 10/10 Excellent "Loved this hotel. Great location, very helpful staff. Just be aware that they will take a $750 barge from your bank card on arrival, however, that means you can charge food and drinks back to your room. The balance is settled on departure " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information) ![Taj Campton Place](//images.trvl-media.com/lodging/1000000/30000/23400/23383/d044cc49_y.jpg) ### Taj Campton Place 10/10 Excellent "The staff and manager were all very receptive to all our requests. We are most impressed and look forward to staying at The Taj on our next visit." [](https://expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) ![The Pickwick Hotel](//images.trvl-media.com/lodging/1000000/20000/11800/11793/060ec935_y.jpg) ### The Pickwick Hotel 10/10 Excellent "Lovely people working at this hotel. Old but clean and everytging you need. Right next to union square at great value" [](https://expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) ![FOUND Hotel Carlton, Nob Hill](//images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/818bb89d_y.jpg) ### FOUND Hotel Carlton, Nob Hill 10/10 Excellent "Very friendly and helpful staff, plus cute and clean rooms. Would definitely stay here again!" [](https://expedia.ca/San-Francisco-Hotels-FOUND-Hotel-San-Francisco-Carlton.h103126565.Hotel-Information) ![Mayflower Hotel](//images.trvl-media.com/lodging/117000000/116240000/116230300/116230279/943d9246_y.jpg) ### Mayflower Hotel 10/10 Excellent "I stayed at the Mayflower during a conference because SF was sold out. I travel a lot for business and stay at marriotts. The online reviews prepared me well - this is an old building with a single person at the desk, old elevator, and very basic amenities. If you are good with that (and I love old buildings and don’t rely on hotels toiletries) then this is a comfortable stay - and I’m glad I took the chance to be near Moscone. Everything was exactly as described - and the person at the front desk was very helpful. I would absolutely stay here again. " [](https://expedia.ca/San-Francisco-Hotels-Mayflower-Hotel.h116230279.Hotel-Information) ![InterContinental Mark Hopkins by IHG](//images.trvl-media.com/lodging/1000000/30000/24700/24620/dc12fb50_y.jpg) ### InterContinental Mark Hopkins by IHG 10/10 Excellent "Great service! Gave us early check-in with no problems. " [](https://expedia.ca/San-Francisco-Hotels-InterContinental-Mark-Hopkins.h24620.Hotel-Information) ## Find out more about Downtown San Francisco ## Downtown San Francisco Hotels Guide Expedia.ca offers a selection of 973 hotels in Downtown San Francisco. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Downtown San Francisco. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Downtown San Francisco neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Downtown San Francisco, San Francisco now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [4 Star Hotels in San Francisco](https://www.expedia.ca/4Star-San-Francisco-Hotels.s40-0-d178305.Travel-Guide-Filter-Hotels) - [5 Star Hotels in San Francisco](https://www.expedia.ca/5Star-San-Francisco-Hotels.s50-0-d178305.Travel-Guide-Filter-Hotels) - [Hotels near American Conservatory Theater](https://www.expedia.ca/American-Conservatory-Theater-Hotels.0-l6065733-0.Travel-Guide-Filter-Hotels) - [Red Lion Hotels in Chinatown](https://www.expedia.ca/Chinatown-San-Francisco-Hotels-Red-Lion.0-n6004910-0--bRedLion.Travel-Guide-Filter-Hotels) - [Independent Hotels in Fillmore District](https://www.expedia.ca/Fillmore-District-San-Francisco-Hotels-Independent.0-n553248635074841945-0--bIndependent.Travel-Guide-Filter-Hotels) - [Fairmont Hotels in Financial District](https://www.expedia.ca/Financial-District-San-Francisco-Hotels-Fairmont.0-n6056710-0--bFairmont.Travel-Guide-Filter-Hotels) - 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[Luxury Hotels in Tenderloin](https://www.expedia.ca/Tenderloin-San-Francisco-Hotels-Luxury-Hotel.0-n6203136-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Tenderloin](https://www.expedia.ca/Tenderloin-San-Francisco-Hotels-Oceanfront-Hotels.0-n6203136-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Ski Hotels in Tenderloin](https://www.expedia.ca/Tenderloin-San-Francisco-Hotels-Ski-Hotel.0-n6203136-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Tenderloin Hotels](https://www.expedia.ca/Tenderloin-San-Francisco-Hotels.0-n6203136-0.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Best-Western.0-n800129-0--bBestWestern.Travel-Guide-Filter-Hotels) - [Citizenm Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-CitizenM-Hotels.0-n800129-0--bCitizenMHotels.Travel-Guide-Filter-Hotels) - [Highgate Independent Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Highgate-Independent.0-n800129-0--bHighgateIndependent.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Hilton-Hotels.0-n800129-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Independent Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Independent.0-n800129-0--bIndependent.Travel-Guide-Filter-Hotels) - [Kimpton Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Kimpton-Hotels.0-n800129-0--bKimptonHotels.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n800129-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Union Square Hotels](https://www.expedia.ca/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Hotels near Warfield Theatre](https://www.expedia.ca/Warfield-Theatre-Hotels.0-l6155642-0.Travel-Guide-Filter-Hotels) - [Flights to San Francisco](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights) - [Flights from Vancouver to San Francisco](https://www.expedia.ca/lp/flights/178315/178305/vancouver-to-san-francisco) - [Flights from Vancouver (YVR) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco) - [Flights from Toronto (YYZ) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco) - [Alcove Theater](https://www.expedia.ca/Alcove-Theater-Union-Square.d6155591.Vacation-Attraction) - [Visit Tenderloin](https://www.expedia.ca/San-Francisco-Tenderloin.dx6203136) - [Visit Union Square](https://www.expedia.ca/San-Francisco-Union-Square.dx800129) - [San Francisco Vacations](https://www.expedia.ca/San-Francisco.d178305.Destination-Travel-Guides) - [Visit San Francisco](https://www.expedia.ca/San-Francisco.dx178305) - [All inclusive Vacation Packages San Francisco](https://www.expedia.ca/lp/theme-vacations/all-inclusive-vacations/178305/San-Francisco) - [Car rentals near San Francisco](https://www.expedia.ca/Car-Rentals-In-San-Francisco.d178305.Car-Rental-Guide) - [Convertible Car Rentals in San Francisco](https://www.expedia.ca/Convertible-Car-Rentals-In-San-Francisco.d178305-tConvertible.Car-Rental-Guide-Class) - [Enterprise Rental Cars in San Francisco](https://www.expedia.ca/Enterprise-Car-Rentals-In-San-Francisco.d178305-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in San Francisco](https://www.expedia.ca/Hertz-Car-Rentals-In-San-Francisco.d178305-c40.Car-Rental-Guide-Suppliers) - [Pickup Car Rentals in San Francisco](https://www.expedia.ca/Pickup-Car-Rentals-In-San-Francisco.d178305-tPickup.Car-Rental-Guide-Class) - [San Francisco Vacation Rentals](https://www.expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals) - [Things to do in San Francisco](https://www.expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities) - [Book Hotels in Downtown San Francisco on Expedia.com](https://www.expedia.com/Downtown-San-Francisco-San-Francisco-Hotels-Highgate-Independent.0-n6151902-0--bHighgateIndependent.Travel-Guide-Filter-Hotels)