Title: Book the Best Downtown Key West SPA Resorts from CA $355 - Spa Hotels in Downtown Key West, Key West | Expedia.ca [Downtown Key West Travel Guide](https://expedia.ca/Key-West-Downtown-Key-West.dx553248635976470405)[Flights to Key West](https://expedia.ca/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)[Things to do in Key West](https://expedia.ca/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)[Downtown Key West Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-Key-West.d553248635976470405.Car-Rental-Guide)[Downtown Key West Vacations](https://expedia.ca/Downtown-Key-West.d553248635976470405.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63795-Florida-Keys.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Downtown Key West, Key West from CA $355 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Downtown Key West Spa Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976470405&startDate=2025-10-24&endDate=2025-10-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976470405&startDate=2025-10-25&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976470405&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976470405&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Downtown Key West Spa Hotels ![Couples treatment rooms, facials, massages](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/edae2602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/4eda9d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, beach views ](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/8f43a3d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/b4576547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southernmost Beach Resort and Guesthouses Old Town Key West 8.6/10 Excellent (2817) "A great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerri CA $224 CA $355 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/4d671ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/3ac97dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/f2c5f58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/acfeb5a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Opal Key Resort & Marina, Key West Old Town Key West 9.2/10 Wonderful (1001) "Staff was tremendous and location is perfect!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheryl CA $348 CA $447 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Opal-Key-Resort-Marina.h17442701.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/10000/1000/901/c73d9fc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/1000/901/399f6b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/1000/901/09ed2e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, ocean views ](https://images.trvl-media.com/lodging/1000000/10000/1000/901/ea2f021f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Centric Key West Resort and Spa Key West Historic District 9.0/10 Wonderful (1013) "Location location location is why u stay here. Walking distance to everything, 40 spot for parking is a bit steep but had a great stay. We would stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $257 CA $381 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information) ![Body treatments, aromatherapy, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/7a4ee33e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/50962e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/a299c4a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/05980c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Key Resort - A Noble House Resort Key West Historic District 9.2/10 Wonderful (1003) "Great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarit CA $272 CA $414 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Key-West-Hotels-Ocean-Key-Resort-A-Noble-House-Resort.h16682.Hotel-Information) ![Couples treatment rooms, body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/8f5721fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/bd916166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/1b169515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/7826c1a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Marina Key West, Curio Collection by Hilton Old Town Key West 8.4/10 Very good (404) "Yes property is in an excellent location and the rooms and common areas were very good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale CA $327 CA $452 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information) ![Outdoor treatment areas, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/6f2bdc21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/02b8eaa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/b515d08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/eb7f9b00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reach Key West, Curio Collection by Hilton Old Town Key West 8.4/10 Very good (1001) "Great staff, view and food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $292 CA $413 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-The-Reach-Key-West.h457821.Hotel-Information) ![Hot tub, body treatments, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/w4521h2996x0y0-d3c62846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/d639c41f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Oceanfront | View from room](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/f51cc383.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Dockside) | Living room](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/053d9529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pier House Resort & Spa Key West Historic District 9.0/10 Wonderful (1005) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Billy CA $502 CA $656 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Pier-House-Resort-Spa.h19307.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08®ionId=553248635976470405&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Downtown Key West ### Top Downtown Key West attractions for a relaxing vacation Downtown Key West is a paradise for those seeking a rejuvenating getaway infused with the vibrant spirit of the island. Begin your adventure at the Ernest Hemingway Home and Museum, where you can wander through lush gardens and connect with the literary history of this iconic figure. For a dose of local culture, visit the Key West Butterfly and Nature Conservatory, where you’ll be surrounded by hundreds of fluttering butterflies in a tranquil setting that feels almost spa-like. After a day of exploration, unwind at the picturesque Mallory Square, known for its stunning sunsets and street performances that create a lively, yet relaxing atmosphere. If you’re feeling adventurous, consider a snorkelling tour of the nearby coral reefs, an exhilarating way to connect with nature before retreating to your hotel. The luxurious spa hotels in this area, such as the Ocean Key Resort & Spa, offer exquisite treatments like ocean-inspired massages and rejuvenating facials, ensuring that you feel pampered after a day of activity. With attentive service and stunning views, your stay will be both comfortable and indulgent, creating an unforgettable escape that perfectly balances relaxation and adventure. ## Top Downtown Key West Hotel Reviews ![The Cabana Inn Key West - Adults Only](//images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/98bddc65_y.jpg) ### The Cabana Inn Key West - Adults Only 10/10 Excellent "Great" [](https://expedia.ca/Key-West-Hotels-The-Cabana-Inn-Key-West-Adults-Only.h6576609.Hotel-Information) ![Casa Marina Key West, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/12400/12346/be8c9450_y.jpg) ### Casa Marina Key West, Curio Collection by Hilton 10/10 Excellent "This hotel is beautiful. Great view from the room. Staff is amazing " [](https://expedia.ca/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information) ![Hyatt Centric Key West Resort and Spa](//images.trvl-media.com/lodging/1000000/10000/1000/901/0b72a249_y.jpg) ### Hyatt Centric Key West Resort and Spa 10/10 Excellent "👍" [](https://expedia.ca/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information) ![Almond Tree Inn Hotel - Adults Only](//images.trvl-media.com/lodging/1000000/810000/809100/809031/3d7c7063_y.jpg) ### Almond Tree Inn Hotel - Adults Only 10/10 Excellent "Great location. Staff was friendly and helpful. Would stay here again. " [](https://expedia.ca/Key-West-Hotels-Almond-Tree-Inn.h809031.Hotel-Information) ![Southernmost Beach Resort and Guesthouses](//images.trvl-media.com/lodging/1000000/870000/863400/863329/026f10af_y.jpg) ### Southernmost Beach Resort and Guesthouses 10/10 Excellent "A great place to stay!" [](https://expedia.ca/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information) ![DoubleTree Resort by Hilton Grand Key - Key West](//images.trvl-media.com/lodging/1000000/480000/470900/470834/be4147fb_y.jpg) ### DoubleTree Resort by Hilton Grand Key - Key West 10/10 Excellent "Shuttle was great and the staff was great" [](https://expedia.ca/Key-West-Hotels-DoubleTree-Resort-By-Hilton-Grand-Key-Key-West.h470834.Hotel-Information) ![Pegasus International Hotel](//images.trvl-media.com/lodging/1000000/980000/977400/977303/81c4c567_y.jpg) ### Pegasus International Hotel 10/10 Excellent "I loved the location as well as the ease of loading and unloading right at the curb. The parking was very convenient: just a half block away. I didn't know there was a rooftop pool and lounging area! Great surprise and a wonderful spot to people watch Duval Street. The room was perfect for the 2 of us. I didnt comment on the breakfast as we didn't eat there. Overall A+ rating!" [](https://expedia.ca/Key-West-Hotels-Pegasus-International-Hotel.h977303.Hotel-Information) ![The Gardens Hotel](//images.trvl-media.com/lodging/1000000/30000/20800/20796/424c57d6_y.jpg) ### The Gardens Hotel 10/10 Excellent "Best place ever." [](https://expedia.ca/Key-West-Hotels-The-Gardens-Hotel.h20796.Hotel-Information) ![Paradise Inn Key West - Adults Only](//images.trvl-media.com/lodging/4000000/3930000/3924900/3924835/069168f1_y.jpg) ### Paradise Inn Key West - Adults Only 10/10 Excellent "Handy location, quiet, well kept, helpful staff." [](https://expedia.ca/Key-West-Hotels-Paradise-Inn-Key-West-Adults-Only.h3924835.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Downtown Key West? > Treat yourself to some pampering and book a hotel with a spa. Spa hotels are a great way to break out of your daily routine and add a layer of luxury to your weekend away. ### What's there to see and do in Downtown Key West? > When you're in Downtown Key West, enjoy exploring the sights and attractions here including Duval Street, Ernest Hemingway Home and Museum, and San Carlos Institute - Casa Cuba. If you have extra time while you're in the area, you might want to stop by Jackson Square and Tennessee Williams Key West Exhibit. ### What is a Downtown Key West spa hotel? > Spa hotels in Downtown Key West have on-site spas and offer services such as couples massages and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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