Title: Book the Best ADVENTURE Hotels in Downtown Amarillo in 2025 | Expedia.ca [Downtown Amarillo Travel Guide](https://expedia.ca/Amarillo-Downtown-Amarillo.dx897247168017158144)[Vacation Rentals in Amarillo](https://expedia.ca/Amarillo-Vacation-Rentals.d371.Travel-Guide-VacationRentals)[Flights to Amarillo](https://expedia.ca/Cheap-Flights-To-Amarillo.d371.Travel-Guide-Flights)[Things to do in Amarillo](https://expedia.ca/Things-To-Do-In-Amarillo.d371.Travel-Guide-Activities)[Downtown Amarillo Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-Amarillo.d897247168017158144.Car-Rental-Guide)[Downtown Amarillo Vacations](https://expedia.ca/Downtown-Amarillo.d897247168017158144.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/292ff63a131209caf2b3b80643a0bef5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels & Resorts for Couples in Downtown Amarillo, TX from CA $100 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Downtown Amarillo Hotels & Resorts for Couples Tonight [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=897247168017158144&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=897247168017158144&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=897247168017158144&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=897247168017158144&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Downtown Amarillo Hotels & Resorts for Couples ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96040000/96038800/96038725/653e8d87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96040000/96038800/96038725/f49a5e6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/97000000/96040000/96038800/96038725/3f7b5f8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/97000000/96040000/96038800/96038725/eecd6608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jackson St Duo. Near I-40, DT, & Rt 66 Historic Dist. Perfect for larger groups Downtown Amarillo 8.0/10 Very good (2) "Great property hidden just far enough off higway to be close yet quiet. Great host, very thorough set up and nice decor. Would recommend for sure!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor J. CA $174 CA $374 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Amarillo-Hotels-Jackson-St-Duo-Near-I-40.h96038725.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/9300/9230/d0453ea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9300/9230/3db98361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9300/9230/6230633a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9300/9230/541ce9e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Amarillo East Barrio 8.4/10 Very good (1661) "The breakfast was good, and the staff were very friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) HUI CA $87 CA $100 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Amarillo-Hotels-Baymont-By-Wyndham-Amarillo-East.h9230.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/5203d67e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/bdcef4d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/9db02856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/10000000/9740000/9733400/9733400/43f00102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Amarillo Soncy 9.0/10 Wonderful (1002) "Great place! Clean rooms with lots of great extras like a pool, grilling area, seating areas inside and outside and good breakfast too. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt CA $137 CA $157 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Amarillo-Hotels-Home2-Suites-By-Hilton-Amarillo.h9733400.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/43000000/42370000/42365600/42365577/c7f135c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/43000000/42370000/42365600/42365577/f08fc4f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, Netflix, Hulu, streaming services](https://images.trvl-media.com/lodging/43000000/42370000/42365600/42365577/25b5832a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/43000000/42370000/42365600/42365577/b1e55ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Unique space on WTAMU campus. Walk to anything and everything! Canyon 9.8/10 Exceptional (107) "Great value" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joana CA $112 CA $228 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Bouvet-Island-Hotels-Unique-Space-On-Wtamu-Campus-Walk-To-Anything-And-Everything.h42365577.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/73000000/72040000/72036700/72036655/c2c8dbff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/73000000/72040000/72036700/72036655/a56807bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/73000000/72040000/72036700/72036655/1f20d155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/73000000/72040000/72036700/72036655/2d7619d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### McKinley House Prime - Patio, Pool and Garage Amarillo 9.6/10 Exceptional (49) "Very nice home to stay in ,my family and I really enjoyed our stay.Highly recommend any one's stay .Very clean home,very nice neighborhood, the host was very helpful with the questions that we had.We greatly appreciate you all. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hever A. CA $171 CA $224 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Amarillo-Hotels-McKinley-House-Too.h72036655.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109830000/109828400/109828383/21d70317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball](https://images.trvl-media.com/lodging/110000000/109830000/109828400/109828383/33f3ce79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109830000/109828400/109828383/7dad3344.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/110000000/109830000/109828400/109828383/871781c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Emery’s Place GAME ROOM, 4BD 2BR near Palo Duro Canyon Canyon 9.8/10 Exceptional (6) "Very comfortable, we felt at home.Great appliances. Nice furnishings." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan C. CA $112 CA $383 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Canyon-Hotels-Emerys-Place-4-Bdrm-Game.h109828383.Hotel-Information) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104180000/104180000/104179991/68bb3a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104180000/104180000/104179991/7ac4d55b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104180000/104180000/104179991/e3885b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/105000000/104180000/104180000/104179991/5be404b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Retreat in heart of Amarillo Amarillo 9.0/10 Wonderful (2) "We enjoyed our stay very much.. the neighbors were so friendly and the neighborhood was very nice and quiet.. The bed was very comfortable and the place was super clean and inviting.. we will definitely be back! Overall we loved the place very much. Thank you for having us! God bless you " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley S. CA $113 CA $223 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Amarillo-Hotels-Charming-Retreat-In-Heart-Of-Amarillo.h104179991.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68890000/68887900/68887819/24239b2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, offices](https://images.trvl-media.com/lodging/69000000/68890000/68887900/68887819/b30a3f00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68890000/68887900/68887819/19857b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/69000000/68890000/68887900/68887819/08603761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yellow Cottage Home Close to I-40 and I-27 Amarillo 10/10 Exceptional (89) "Had a great stay on our way through Amarillo." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clint B. CA $137 CA $341 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Amarillo-Hotels-Yellow-Cottage-Home-Close-To-I-40-And-I-27.h68887819.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/68000000/67640000/67634800/67634790/ecdd015a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/68000000/67640000/67634800/67634790/2447daf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/68000000/67640000/67634800/67634790/f9770b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/68000000/67640000/67634800/67634790/a655f87b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hidden Hideaway with a View (Close to I-40/City) - Safe & Away from the Hotels Amarillo 10/10 Exceptional (70) "Great stay for a road trip. Quiet and away from the highway. Perfect for a night or two. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lauren H. CA $121 CA $186 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Amarillo-Hotels-Hidden-Hideaway-With-A-View.h67634790.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/89000000/88780000/88779900/88779823/00c69ed4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, printers](https://images.trvl-media.com/lodging/89000000/88780000/88779900/88779823/47925c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, printers](https://images.trvl-media.com/lodging/89000000/88780000/88779900/88779823/c5167e0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/89000000/88780000/88779900/88779823/222ee75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Family friendly, Business friendly, Updated, fully stocked, pets welcome Amarillo 10/10 Exceptional (17) "Great place to stay! We stayed one night on our way out west on a road trip, and again on our way back. Clean and had plenty of room for our family. Thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa M. CA $178 CA $411 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Amarillo-Hotels-Family-Friendly.h88779823.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07®ionId=897247168017158144&adults=2&nearby_group=recreation&sort=RECOMMENDED&openPlayBack=true) ## Top Downtown Amarillo Hotel Reviews ![Drury Inn & Suites Amarillo](//images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/887f87c2_y.jpg) ### Drury Inn & Suites Amarillo 10/10 Excellent "Looking a little dated, especially in bathroom, but overall stay was excellent." [](https://expedia.ca/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) ![Spark by Hilton Amarillo East](//images.trvl-media.com/lodging/1000000/920000/918600/918554/51599ed7_y.jpg) ### Spark by Hilton Amarillo East 10/10 Excellent "All was great" [](https://expedia.ca/Amarillo-Hotels-Ashmore-Inn-Suites.h918554.Hotel-Information) ![Baymont by Wyndham Amarillo East](//images.trvl-media.com/lodging/1000000/10000/9300/9230/d0453ea1_y.jpg) ### Baymont by Wyndham Amarillo East 10/10 Excellent "Very nice hot breakfast, very friendly service and very comfortable room. The only complaint I could mention is that we requested a ground floor room due to no elevator and a difficulty with steps and they could not help us with that. Otherwise, a great hotel!" [](https://expedia.ca/Amarillo-Hotels-Baymont-By-Wyndham-Amarillo-East.h9230.Hotel-Information) ![Holiday Inn Express & Suites Amarillo West by IHG](//images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/02449019_y.jpg) ### Holiday Inn Express & Suites Amarillo West by IHG 10/10 Excellent "Yes" [](https://expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) ![Country Inn & Suites by Radisson, Amarillo I-40 West, TX](//images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/0abb04c2_y.jpg) ### Country Inn & Suites by Radisson, Amarillo I-40 West, TX 10/10 Excellent "All looked good. 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[Pousadas in Amarillo](https://www.expedia.ca/Amarillo-Pousadas.d371-aaPousadas.Travel-Guide-Accommodation) - [Vacation Homes in Amarillo](https://www.expedia.ca/Amarillo-Private-Vacation-Homes.d371-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Ranches in Amarillo](https://www.expedia.ca/Amarillo-Ranches.d371-aaRanches.Travel-Guide-Accommodation) - [Resorts in Amarillo](https://www.expedia.ca/Amarillo-Resort-Hotels.d371-aaResortHotels.Travel-Guide-Accommodation) - [Townhomes in Amarillo](https://www.expedia.ca/Amarillo-Townhomes.d371-aaTownhomes.Travel-Guide-Accommodation) - [Hotels near Amarillo Zoo](https://www.expedia.ca/Amarillo-Zoo-Hotels.0-l6080847-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Barrio](https://www.expedia.ca/Barrio-Amarillo-Hotels-Luxury-Hotel.0-n897259818119798784-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Barrio](https://www.expedia.ca/Barrio-Amarillo-Hotels-Pet-Friendly-Hotel.0-n897259818119798784-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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[Soncy Hotels](https://www.expedia.ca/Soncy-Amarillo-Hotels.0-n3000007996-0.Travel-Guide-Filter-Hotels) - [Hotels near Tradewind](https://www.expedia.ca/Tradewind-Airport-Hotels.0-aTDW-0.Travel-Guide-Filter-Hotels) - [Hotels near Tri State Exposition](https://www.expedia.ca/Tri-State-Exposition-Hotels.0-l6215490-0.Travel-Guide-Filter-Hotels) - [Hotels near Westgate Mall](https://www.expedia.ca/Westgate-Mall-Hotels.0-l6080887-0.Travel-Guide-Filter-Hotels) - [Hotels near Wonderland Amusement Park](https://www.expedia.ca/Wonderland-Amusement-Park-Hotels.0-l6080889-0.Travel-Guide-Filter-Hotels) - [Flights to Amarillo](https://www.expedia.ca/Cheap-Flights-To-Amarillo.d371.Travel-Guide-Flights) - [Flights from Rick Husband Amarillo Intl.](https://www.expedia.ca/lp/airports/ama/flights-from-rick-husband-amarillo-intl-airport) - [Flights from Amarillo](https://www.expedia.ca/lp/flights/371/flights-from-amarillo) - [Flights from Nashville (BNA) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/bna/ama/nashville-to-amarillo) - 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Airport (PAE) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/pae/ama/seattle-paine-field-intl-airport-to-amarillo) - [Flights from Pittsburgh (PIT) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/pit/ama/pittsburgh-to-amarillo) - [Flights from Temple (TPL) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/tpl/ama/temple-to-amarillo) - [Flights from Vernal (VEL) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/vel/ama/vernal-to-amarillo) - [Flights from Williston (XWA) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/xwa/ama/williston-to-amarillo) - [Flights from Edmonton (YEG) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yeg/ama/edmonton-to-amarillo) - [Flights from Hamilton (YHM) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yhm/ama/hamilton-to-amarillo) - [Flights from Montreal (YMQ) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/ymq/ama/montreal-to-amarillo) - [Flights from Norway House (YNE) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yne/ama/norway-house-to-amarillo) - [Flights from Ottawa (YOW) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yow/ama/ottawa-to-amarillo) - [Flights from Regina (YQR) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yqr/ama/regina-to-amarillo) - [Flights from Montreal (YUL) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yul/ama/montreal-to-amarillo) - [Flights from Vancouver (YVR) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yvr/ama/vancouver-to-amarillo) - [Flights from Winnipeg (YWG) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/ywg/ama/winnipeg-to-amarillo) - [Flights from Saskatoon (YXE) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yxe/ama/saskatoon-to-amarillo) - [Flights from Calgary (YYC) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yyc/ama/calgary-to-amarillo) - [Flights from Victoria (YYJ) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yyj/ama/victoria-to-amarillo) - [Flights from Toronto (YYZ) to Amarillo (AMA)](https://www.expedia.ca/lp/flights/yyz/ama/toronto-to-amarillo) - [Amarillo Vacations](https://www.expedia.ca/Amarillo.d371.Destination-Travel-Guides) - [John Stiff Memorial Dog Park](https://www.expedia.ca/John-Stiff-Memorial-Dog-Park-Amarillo.d553248621561866764.Vacation-Attraction) - [Avis Rental Cars in Amarillo](https://www.expedia.ca/Avis-Car-Rentals-In-Amarillo.d371-c41.Car-Rental-Guide-Suppliers) - [Car rentals near Amarillo](https://www.expedia.ca/Car-Rentals-In-Amarillo.d371.Car-Rental-Guide) - [Rental cars Rick Husband Amarillo Intl. airport](https://www.expedia.ca/Car-Rentals-In-Rick-Husband-Amarillo-Intl.d6026131.Car-Rental-Guide) - [Pickup Car Rentals near Don and Sybil Harrington Cancer Center](https://www.expedia.ca/Pickup-Car-Rentals-In-Don-And-Sybil-Harrington-Cancer-Center.d6080861-tPickup.Car-Rental-Guide-Class) - [Things to do in Amarillo](https://www.expedia.ca/Things-To-Do-In-Amarillo.d371.Travel-Guide-Activities) - [Book Hotels in Downtown Amarillo on Expedia.com](https://www.expedia.com/Downtown-Amarillo-Amarillo-Hotels-Couples-Resorts-Hotels.0-n897247168017158144-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)