Title: 10 Best Hotels in Donja Vrežina, Niš for 2026 | Expedia.ca

[Vacation Rentals in Niš](https://expedia.ca/Nis-Vacation-Rentals.d7905.Travel-Guide-VacationRentals)[Flights to Niš](https://expedia.ca/Cheap-Flights-To-Nis.d7905.Travel-Guide-Flights)[Things to do in Niš](https://expedia.ca/Things-To-Do-In-Nis.d7905.Travel-Guide-Activities)[Donja Vrežina Car Rentals](https://expedia.ca/Car-Rentals-In-Donja-Vrezina.d553248635975855786.Car-Rental-Guide)[Donja Vrežina Vacations](https://expedia.ca/Donja-Vrezina.d553248635975855786.Destination-Travel-Guides)

![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check prices for these dates

Tonight

[Mar 7 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975855786&startDate=2026-03-07&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 8 - Mar 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975855786&startDate=2026-03-08&endDate=2026-03-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248635975855786&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248635975855786&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Donja Vrežina hotels

![Lobby](https://images.trvl-media.com/lodging/39000000/38410000/38403800/38403705/b5e8a9a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38410000/38403800/38403705/3fdc5e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/39000000/38410000/38403800/38403705/256e345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Single Room | Bathroom](https://images.trvl-media.com/lodging/39000000/38410000/38403800/38403705/56b9b639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ambasador Hotel

[](https://www.expedia.ca/Nis-Hotels-Ambasador-Hotel.h38403705.Hotel-Information)

Medijana City Center, 4.7 km from Donja Vrežina

9.4/10

Exceptional

(130 reviews)

"A fantastic hotel with a convenient location in the centre of Nis. The staff are friendly and the rooms are very spacious, with wonderful panoramic views of the city. Exceptional value for money."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Tyler

[](https://www.expedia.ca/Nis-Hotels-Ambasador-Hotel.h38403705.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/20000000/19340000/19330300/19330275/c9eb457d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/20000000/19340000/19330300/19330275/1481bcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/20000000/19340000/19330300/19330275/af9dacd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/20000000/19340000/19330300/19330275/5bc8f151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Art Loft Hotel 4\*

[](https://www.expedia.ca/Nis-Hotels-Art-Loft-Hotel.h19330275.Hotel-Information)

Medijana, 4.9 km from Donja Vrežina

9.4/10

Exceptional

(112 reviews)

"Perfect stay..."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

CA $101

CA $111 total

includes taxes & fees

Mar 21 - Mar 22

[](https://www.expedia.ca/Nis-Hotels-Art-Loft-Hotel.h19330275.Hotel-Information)

![Deluxe Double or Twin Room, Balcony](https://images.trvl-media.com/lodging/38000000/37310000/37300400/37300317/e168d9d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double or Twin Room, Balcony](https://images.trvl-media.com/lodging/38000000/37310000/37300400/37300317/2fae826e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/38000000/37310000/37300400/37300317/47e7cb1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/38000000/37310000/37300400/37300317/85008f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Garni Hotel Boutique 25h

[](https://www.expedia.ca/Nis-Hotels-Boutique-25h.h37300317.Hotel-Information)

Medijana City Center, 5.3 km from Donja Vrežina

8.8/10

Excellent

(35 reviews)

"Excellent value for money. Good staff."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Dragan

CA $95

CA $105 total

includes taxes & fees

Mar 21 - Mar 22

[](https://www.expedia.ca/Nis-Hotels-Boutique-25h.h37300317.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21400000/21393800/21393789/f719cb6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/22000000/21400000/21393800/21393789/938f1ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms](https://images.trvl-media.com/lodging/22000000/21400000/21393800/21393789/1996166a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms](https://images.trvl-media.com/lodging/22000000/21400000/21393800/21393789/8638635a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lux & Spa Zen

[](https://www.expedia.ca/Nis-Hotels-Lux-Spa-Zen.h21393789.Hotel-Information)

2.8 km from Donja Vrežina

9.4/10

Exceptional

(63 reviews)

"Nice place to stay and amazing breakfast 😺"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Zeljko

[](https://www.expedia.ca/Nis-Hotels-Lux-Spa-Zen.h21393789.Hotel-Information)

![Outdoor pool, open 9:00 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/45000000/44650000/44648200/44648196/c8ddca4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (EUR 7.5 per person)](https://images.trvl-media.com/lodging/45000000/44650000/44648200/44648196/b0b264d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/45000000/44650000/44648200/44648196/73ab5cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/45000000/44650000/44648200/44648196/9085e383.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tami Residence

[](https://www.expedia.ca/Nis-Hotels-Tami-Residence.h44648196.Hotel-Information)

5.9 km from Donja Vrežina

8.0/10

Very good

(17 reviews)

"The staff were very friendly and helpful. The room was big and the bed was sooooo good!! It also has a nice view! "

![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg)

Maria Sagen

[](https://www.expedia.ca/Nis-Hotels-Tami-Residence.h44648196.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/49000000/48190000/48182200/48182104/ed465de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/49000000/48190000/48182200/48182104/98fb065e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/49000000/48190000/48182200/48182104/49a46c17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, free toiletries, hair dryer, bathrobes](https://images.trvl-media.com/lodging/49000000/48190000/48182200/48182104/d56e58d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Eter Hotel

[](https://www.expedia.ca/Nis-Hotels-Eter-Hotel.h48182104.Hotel-Information)

Medijana City Center, 4.8 km from Donja Vrežina

8.6/10

Excellent

(72 reviews)

"Perfect location, good price."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Jason

[](https://www.expedia.ca/Nis-Hotels-Eter-Hotel.h48182104.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/78000000/77060000/77056600/77056509/48c148f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/78000000/77060000/77056600/77056509/b5cb3ca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/78000000/77060000/77056600/77056509/01b126b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/78000000/77060000/77056600/77056509/f47b54d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOTEL NAIS

[](https://www.expedia.ca/Nis-Hotels-HOTEL-NAIS.h77056509.Hotel-Information)

13.3 km from Donja Vrežina

9.2/10

Wonderful

(14 reviews)

"We had a wonderful stay. The room was very clean and comfortable, and the staff were always welcoming and helpful. We especially enjoyed the amenities and the relaxing atmosphere. Highly recommended!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kaya

CA $110

CA $121 total

includes taxes & fees

Mar 21 - Mar 22

[](https://www.expedia.ca/Nis-Hotels-HOTEL-NAIS.h77056509.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/97000000/96760000/96750200/96750175/33fa1b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment | Living area](https://images.trvl-media.com/lodging/97000000/96760000/96750200/96750175/dcc49ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/97000000/96760000/96750200/96750175/5115fd72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Twin Room](https://images.trvl-media.com/lodging/97000000/96760000/96750200/96750175/cb2ce033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury Hotel King Bo

[](https://www.expedia.ca/Nis-Hotels-Luxury-Hotel-King-Bo.h96750175.Hotel-Information)

Medijana City Center, 5.2 km from Donja Vrežina

7.0/10

Good

(12 reviews)

"The hotel would not be bad because the building is beautiful while the carpet is so old and stained even disgusting but the staff is nice bads are comfort "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Eliza

CA $104

CA $115 total

includes taxes & fees

Mar 26 - Mar 27

[](https://www.expedia.ca/Nis-Hotels-Luxury-Hotel-King-Bo.h96750175.Hotel-Information)

![Double Room, Balcony](https://images.trvl-media.com/lodging/24000000/23600000/23593200/23593126/82f773ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/24000000/23600000/23593200/23593126/022811e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/24000000/23600000/23593200/23593126/25c3fcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/24000000/23600000/23593200/23593126/8edf6ad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  Bloom Inn

[](https://www.expedia.ca/Nis-Hotels-Bloom-Inn.h23593126.Hotel-Information)

Medijana City Center, 4.8 km from Donja Vrežina

9.2/10

Wonderful

(83 reviews)

"Great stay in a beautiful room and the staff were very helpful. Bar downstairs was very nice "

![Ireland](https://a.travel-assets.com/egds/marks/flags/ie.svg)

William

CA $63

CA $70 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Nis-Hotels-Bloom-Inn.h23593126.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-21&endDate=2026-03-22&regionId=553248635975855786&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Donja Vrežina

Find the best Donja Vrežina areas and neighborhoods for the activities you enjoy most. 

- Medijana
- Medijana City Center

![Niš is notable as the birthplace of Constantine The Great, born in 313. AD. He is the first Christian Roman Emperor and the founder of Constantinopole.
#UrbanJungle Photo contest](https://images.trvl-media.com/place/7905/8dd09e85-ff1e-45ec-b3ec-fc32ae31a9c5.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Sasa Nikolic

![Niš.
Administrative center of southern part of  Serbia
#UrbanJungle Photo contest](https://images.trvl-media.com/place/7905/62252d1f-61d1-4645-9e07-b710f8667104.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Sasa Nikolic

![Saborna Crkva is a beautiful Orthodox Church in the city of Niš.
The church was opened in 1878, but was damaged by an Allied bombing during World War II and also by fire in 2001. It was rebuilt and consecrated in 2006.](https://images.trvl-media.com/place/7905/4a4ab94f-9ade-403d-8fda-ed1e89393e26.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Megan @ Pegs on the Line

![The Skull Tower is as freaky as it is fascinating. 
The skulls are from the victims of a failed attempt by the Serbs to claim back their territory from Ottoman rulers in 1809. The tower was built on the side of “Via Militaris” (Military Road), which was the main route connecting Belgrade to Istanbul, as a warning to any potential attackers.
Go to the information office to buy your ticket and someone will unlock the tower for you.
http://pegsontheline.com/how-nis-restored-my-faith-in-couchsurfing-2/ ](https://images.trvl-media.com/place/7905/25610429-31a7-4c41-827e-9f68b4120b80.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Megan @ Pegs on the Line

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976006814)

![Medijana map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7BikgGi_qdCCcCm%40%7BByC%7BEcDuBiNyEp%40gIQmKaG_Xs%40gHyAqEwKyO%7DEmO%3F%7B%40n%40Ak%40oDUcIvAsb%40_AwWb%40mEhEcQjBa%60%40_%40qJ_CePMeHl%40sGtA%7BElMsUtLgWlA%7DDlAkd%40sC%7BTEiFjJaj%40rG_BbHxAzCkFzLS%7E%40bFh%40l%40%3F%7CGbIYGhCjBGCR%7EEzAdGbAvFO%7BEzl%40BbDm%40nAaC%60WwCzc%40wJ%7C_A%7BCza%40aBhsAuElq%40JtJhCrd%40K%7CIaA%7EGmBbGcPdY%7B%40MqBvB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ZsfexqjVuPpRWlt_8Bnf_dHnjcg=)

### Medijana

If you're spending some time in Medijana, Skull Tower and Mediana are top sights worth seeing. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976006814)

![Niš.
Administrative center of southern part of  Serbia
#UrbanJungle Photo contest](https://images.trvl-media.com/place/7905/62252d1f-61d1-4645-9e07-b710f8667104.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Sasa Nikolic

![Niš is notable as the birthplace of Constantine The Great, born in 313. AD. He is the first Christian Roman Emperor and the founder of Constantinopole.
#UrbanJungle Photo contest](https://images.trvl-media.com/place/7905/8dd09e85-ff1e-45ec-b3ec-fc32ae31a9c5.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Sasa Nikolic

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976396081)

![Medijana City Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:iekgGukqdCkGcAiBmAoSyG%3FmSeH%7BZ%5D_Fy%40qCcGsHyFyJuCsKYgCXYbJG%7EUrLv%40%3FhKzG%7CA%3FbA%7DAbAQhD%7E_%40%60KGzL%7EB%7C%40%7EI%3FzGwAjLyDvI%7BD%60GaDvBiC%60%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=PWB0hbO1iJvl4O6w5kmZG_Gz7QU=)

### Medijana City Center

While visiting Medijana City Center, you might make a stop by sights like Square of King Milan and National Museum Niš. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976396081)

## Top Donja Vrežina Hotel Reviews

![New City Hotel & Restaurant Niš](https://images.trvl-media.com/lodging/20000000/19340000/19332000/19331914/ac7939a0_y.jpg)

### New City Hotel & Restaurant Niš

10/10 Excellent

"It's one of the best hotels in the whole Serbia. Room service and reception staff excellent. Great breakfast with local/traditional options. I will stay again when i visit my family in Nis."

[](https://expedia.ca/Nis-Hotels-New-City-Hotel-Restaurant-Nis.h19331914.Hotel-Information)

![HOTEL NAIS](https://images.trvl-media.com/lodging/78000000/77060000/77056600/77056509/48c148f3_y.jpg)

### HOTEL NAIS

10/10 Excellent

"Very nice and modern hotel, plenty of parking space, overall nice stay and I am satisfied with staff, restaurant and everything "

[](https://expedia.ca/Nis-Hotels-HOTEL-NAIS.h77056509.Hotel-Information)

![Ambasador Hotel](https://images.trvl-media.com/lodging/39000000/38410000/38403800/38403705/b5e8a9a5_y.jpg)

### Ambasador Hotel

10/10 Excellent

"A fantastic hotel with a convenient location in the centre of Nis. The staff are friendly and the rooms are very spacious, with wonderful panoramic views of the city. Exceptional value for money."

[](https://expedia.ca/Nis-Hotels-Ambasador-Hotel.h38403705.Hotel-Information)

![Lux & Spa Zen](https://images.trvl-media.com/lodging/22000000/21400000/21393800/21393789/f719cb6c_y.jpg)

### Lux & Spa Zen

8/10 Good

"Staff was excellent and very friendly. Breakfast was very good. Wifi worked well. Sauna and whirlpool was included and also very nice. "

[](https://expedia.ca/Nis-Hotels-Lux-Spa-Zen.h21393789.Hotel-Information)

![Eter Hotel](https://images.trvl-media.com/lodging/49000000/48190000/48182200/48182104/ed465de7_y.jpg)

### Eter Hotel

10/10 Excellent

"Perfect location, good price."

[](https://expedia.ca/Nis-Hotels-Eter-Hotel.h48182104.Hotel-Information)

![ Bloom Inn](https://images.trvl-media.com/lodging/24000000/23600000/23593200/23593126/82f773ea_y.jpg)

###  Bloom Inn

10/10 Excellent

"Great stay in a beautiful room and the staff were very helpful. Bar downstairs was very nice "

[](https://expedia.ca/Nis-Hotels-Bloom-Inn.h23593126.Hotel-Information)

![Garni Hotel Boutique 25h](https://images.trvl-media.com/lodging/38000000/37310000/37300400/37300317/e168d9d1_y.jpg)

### Garni Hotel Boutique 25h

10/10 Excellent

"Excellent value for money. Good staff."

[](https://expedia.ca/Nis-Hotels-Boutique-25h.h37300317.Hotel-Information)

![Hotel Helm](https://images.trvl-media.com/lodging/115000000/114890000/114885300/114885284/58613558_y.jpg)

### Hotel Helm

10/10 Excellent

"🖐🖐🖐👌👌👌👍👍👍"

[](https://expedia.ca/Nis-Hotels-Hotel-Helm.h114885284.Hotel-Information)

## Frequently asked questions

### What's it like in Donja Vrežina?

### If I need to cancel my hotel reservation in Donja Vrežina, will I receive a refund?

### What can I see and do in this Niš neighborhood?