Title: 10 Best Florence County Luxury Resorts & Hotels for 2026 | Expedia.ca [Florence County Hotels](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Hotel-Destinations)[Vacation Rentals in Florence County](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Vacation-Rental-Destinations)[Florence County Flights](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Flight-Destinations)[Florence County Car Rentals](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Car-Rental-Destinations)[Florence County Vacations](https://expedia.ca/Florence-County.d553248635976432658.Destination-Travel-Guides) ![Florence_FlorenceCivicCenter_6165605_0005](https://images.trvl-media.com/place/6165605/469ba674-c82b-48e7-81cb-5533222130a5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6165605/469ba674-c82b-48e7-81cb-5533222130a5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Florence County ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Florence [](https://expedia.ca/Florence-Hotels-Luxury-Hotel.0-0-d1221-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![a stunning aerial panoramic shot of the blue waters of Lake Hartwell surrounded by vast miles of lush green trees and grass with powerful clouds at sunset in Fair Play South Carolina USA](https://images.trvl-media.com/place/8506/47c9f422-933e-4135-8743-774b754f1db4.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Lake City [](https://expedia.ca/Lake-City-Hotels-Luxury-Hotel.0-0-d8506-tLuxuryHotel.Travel-Guide-Filter-Hotels) ## Check availability on Florence County Luxury Hotels Tonight [Mar 13 - Mar 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-13&endDate=2026-03-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Mar 14 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-14&endDate=2026-03-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-13&endDate=2026-03-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-20&endDate=2026-03-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AFFINITY_SPRING_PROMO_553248635976432658) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Florence-County-Luxury-Hotel.0-0-d553248635976432658-tLuxuryHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Florence-County-Luxury-Hotel.0-0-d553248635976432658-tLuxuryHotel.Hotel-Filter-Destinations) ## Top Florence County Hotel Reviews ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 8/10 Good "We were only booked for one night. The hotel was clean and the gentleman at the desk was very friendly. Our room was very clean and the location was very quiet. " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Staybridge Suites Florence - Civic Center by IHG](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a_y.jpg) ### Staybridge Suites Florence - Civic Center by IHG 10/10 Excellent "Excellent staff Room was clean" [](https://expedia.ca/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![SpringHill Suites by Marriott Florence](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c_y.jpg) ### SpringHill Suites by Marriott Florence 4/10 Poor "My daughter's room was not cleaned. There were wine bottles, trash, dirty towels and bed linens in the room. When staff was alerted to this, they just walked right in without knocking while my daughter and her teammates were changing into their softball uniforms. " [](https://expedia.ca/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Tru by Hilton Florence I-95](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "Everything was great...clean property and friendly staff! " [](https://expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 6/10 Okay "It was ok" [](https://expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "We loved our room spacious and great space for the dogs..." [](https://expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg) ### Hyatt Place Florence Downtown 4/10 Poor "The worst hotel bed I’ve ever tried to sleep on. Stay somewhere else. " [](https://expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 8/10 Good "Clean & friendly staff. Comfortable beds." [](https://expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/7f29240e_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "Great room..breakfast..pet friendly. Pet cost $20.00" [](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [5 Star Hotels in Florence ](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Business Hotels in Charleston ](https://www.expedia.ca/Charleston-Hotels-Business-Hotel.0-0-d179997-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in Charleston ](https://www.expedia.ca/Charleston-Hotels-Green-Sustainable.0-0-d179997-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Charleston ](https://www.expedia.ca/Charleston-Hotels-Hotel-With-Early-Check-In.0-0-d179997-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Charleston ](https://www.expedia.ca/Charleston-Hotels-Hotels-With-A-Lazy-River.0-0-d179997-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [B&B in Darlington ](https://www.expedia.ca/Darlington-Bed-And-Breakfast.d7558-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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