Title: 10 Best Florence County Luxury Resorts & Hotels for 2026 | Expedia.ca [Florence County Hotels](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Hotel-Destinations)[Vacation Rentals in Florence County](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Vacation-Rental-Destinations)[Florence County Flights](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Flight-Destinations)[Florence County Car Rentals](https://expedia.ca/Destinations-In-Florence-County.d553248635976432658.Car-Rental-Destinations)[Florence County Vacations](https://expedia.ca/Florence-County.d553248635976432658.Destination-Travel-Guides) ![Florence_FlorenceCivicCenter_6165605_0005](https://images.trvl-media.com/place/6165605/469ba674-c82b-48e7-81cb-5533222130a5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6165605/469ba674-c82b-48e7-81cb-5533222130a5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Florence County ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Florence [](https://expedia.ca/Florence-Hotels-Luxury-Hotel.0-0-d1221-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![a stunning aerial panoramic shot of the blue waters of Lake Hartwell surrounded by vast miles of lush green trees and grass with powerful clouds at sunset in Fair Play South Carolina USA](https://images.trvl-media.com/place/8506/47c9f422-933e-4135-8743-774b754f1db4.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Lake City [](https://expedia.ca/Lake-City-Hotels-Luxury-Hotel.0-0-d8506-tLuxuryHotel.Travel-Guide-Filter-Hotels) ## Check availability on Florence County Luxury Hotels Tonight [Mar 15 - Mar 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-15&endDate=2026-03-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Mar 16 - Mar 17](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-16&endDate=2026-03-17&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-20&endDate=2026-03-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=553248635976432658&startDate=2026-03-27&endDate=2026-03-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AFFINITY_SPRING_PROMO_553248635976432658) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Florence-County-Luxury-Hotel.0-0-d553248635976432658-tLuxuryHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Florence-County-Luxury-Hotel.0-0-d553248635976432658-tLuxuryHotel.Hotel-Filter-Destinations) ## Top Florence County Hotel Reviews ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "The rooms, lobby, and parking area were all clean and comfortable." [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg) ### Hyatt Place Florence Downtown 4/10 Poor "We were there for 5 nights and no one knocked on our door to clean our room. We had to ask for clean towels and empty our own garbage cans. The service was terrible." [](https://expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Clean room, easy parking, great breakfast" [](https://expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![SpringHill Suites by Marriott Florence](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c_y.jpg) ### SpringHill Suites by Marriott Florence 6/10 Okay "We’ve stayed here several times in the heat 3 years. This least stay the breakfast was disappointing. Grey pork sausage and runny eggs were the hot bar foods. I usually look forward to the hot foods because my gluten and corn allergies rule most other items. The hot oatmeal and toppings were very good. " [](https://expedia.ca/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "The property was renovated and CLEAN. It was the Best stay ever. The staff was friendly. I remembered them as I've stayed at the property prior. I was comfortable and enjoyed my stay. " [](https://expedia.ca/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Tru by Hilton Florence I-95](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "The room was comfortable but just a bit compact. Not complaining just giving an assessment. The tv is n at least a 55 inch flat screen mounted on the wall at a good height above the desk.The bathroom was spacious enough and with a walk-in shower and plenty of lighting. We enjoyed our stay and would highly recommend this hotel." [](https://expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d_y.jpg) ### TownePlace Suites by Marriott Florence 8/10 Good "Very clean room, bathroom.. Only things that weren’t excellent were the towels were fairly rough and bedspread felt short for bed, didn’t come up to chin even. Otherwise was an excellent stay and would stay again. Check in Hannah was great!" [](https://expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f_y.jpg) ### Park Inn by Radisson Florence, SC 6/10 Okay "The room had a peculiar smell. The water pressure was very low in the shower. And the shower floor needed a good scrubbing with bleach. " [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 8/10 Good "Staff very pleasant " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [5 Star Hotels in Florence ](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Business Hotels in Charleston ](https://www.expedia.ca/Charleston-Hotels-Business-Hotel.0-0-d179997-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in Charleston ](https://www.expedia.ca/Charleston-Hotels-Green-Sustainable.0-0-d179997-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Charleston ](https://www.expedia.ca/Charleston-Hotels-Hotel-With-Early-Check-In.0-0-d179997-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - 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