Title: Top Hotels in Antofagasta de la Sierra Department | Expedia.ca [Vacation Rentals in Antofagasta de la Sierra Department](https://expedia.ca/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Vacation-Rental-Destinations)[Antofagasta de la Sierra Department Car Rentals](https://expedia.ca/Destinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Car-Rental-Destinations)[Antofagasta de la Sierra Department Vacations](https://expedia.ca/Antofagasta-De-La-Sierra-Department.d553248635975749483.Destination-Travel-Guides) ![Breathtaking view of the unique Puna Argentina. This area has a great variety of landscape with volcanoes, lakes and mountains.](https://images.trvl-media.com/place/6348231/fb242164-d911-426d-864f-b858a356ff62.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Graciela Arena ![](https://images.trvl-media.com/place/6348231/fb242164-d911-426d-864f-b858a356ff62.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Antofagasta de la Sierra Department ![](https://mediaim.expedia.com/destination/2/bdaecc5a35289f7a555ef5e216022814.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Antofagasta de la Sierra [](https://expedia.ca/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975749483&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Antofagasta-De-La-Sierra-Department.d553248635975749483.Hotel-Destinations) ## Top Antofagasta de la Sierra Department Hotel Reviews ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Antofagasta de la Sierra Department - [Antofagasta de la Sierra Hotels ](https://expedia.ca/Antofagasta-De-La-Sierra-Hotels.d6348231.Travel-Guide-Hotels) ### Explore more hotels - [Hosteria Pucara ](https://expedia.ca/Antofagasta-De-La-Sierra-Hotels-Hosteria-Pucara.h42527742.Hotel-Information) [See a list of all hotels in Antofagasta de la Sierra Department](https://expedia.ca/All-Antofagasta-De-La-Sierra-Department-Hotels.d553248635975749483.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Antofagasta de la Sierra Department on Expedia.com.ar ](https://www.expedia.com.ar/Destinos-En-Departamento-Antofagasta-De-La-Sierra.d553248635975749483.Destinos-con-Hoteles) ### Expedia's Latest Trends Hotels - [Hilton Mississauga/Meadowvale](https://expedia.ca/Toronto-Hotels-Hilton-MississaugaMeadowvale.h27992.Hotel-Information) - [Tokatoka Resort Hotel](https://expedia.ca/Nadi-Hotels-Tokatoka-Resort-Hotel.h5194650.Hotel-Information) - 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