Title: Hotels by Wyndham Hotels in Des Moines from CA $161 | Expedia.ca [Des Moines Travel Guide](https://expedia.ca/Des-Moines.dx601690)[Hotels in Des Moines](https://expedia.ca/Des-Moines-Hotels.d601690.Travel-Guide-Hotels)[Vacation Rentals in Des Moines](https://expedia.ca/Des-Moines-Vacation-Rentals.d601690.Travel-Guide-VacationRentals)[Flights to Des Moines](https://expedia.ca/Cheap-Flights-To-Des-Moines.d601690.Travel-Guide-Flights)[Things to do in Des Moines](https://expedia.ca/Things-To-Do-In-Des-Moines.d601690.Travel-Guide-Activities)[Des Moines Car Rentals](https://expedia.ca/Car-Rentals-In-Des-Moines.d601690.Car-Rental-Guide)[Des Moines Vacation Packages](https://expedia.ca/Des-Moines.d601690.Destination-Travel-Guides) ![Iowa State Capitol](https://images.trvl-media.com/place/601690/d6e0e2f2-7876-4d18-865a-ae2f68f4627c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Wyndham Hotels in Des Moines from CA $161 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Des Moines Wyndham Hotels ![Down comforters, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/20000/12200/12179/f4bdcbac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12200/12179/11edb912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12200/12179/bcb77f34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12200/12179/66a2c139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Ankeny/Des Moines [](https://www.expedia.ca/Des-Moines-Hotels-Ramada-By-Wyndham-Ankeny.h12179.Hotel-Information) Ankeny 6.2/10 (1000) "Very clean. And staff was excellent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $143 CA $161 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Des-Moines-Hotels-Ramada-By-Wyndham-Ankeny.h12179.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=601690&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDes-Moines-Hotels-Wyndham-Hotels.0-0-d601690--bWyndhamHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDes-Moines-Hotels-Wyndham-Hotels.0-0-d601690--bWyndhamHotels.Travel-Guide-Filter-Hotels) ## Top Des Moines Hotel Reviews ![Country Inn & Suites by Radisson, Des Moines West, IA](https://images.trvl-media.com/lodging/1000000/100000/99800/99780/cede0cf8_y.jpg) ### Country Inn & Suites by Radisson, Des Moines West, IA 10/10 Excellent "Clean, quiet and spotless room" [](https://expedia.ca/Des-Moines-Hotels-Country-Inn-Suites-By-Radisson.h99780.Hotel-Information) ![Hyatt Place West Des Moines Jordan Creek](https://images.trvl-media.com/lodging/17000000/16120000/16112600/16112546/f70b7069_y.jpg) ### Hyatt Place West Des Moines Jordan Creek 10/10 Excellent "very clean" [](https://expedia.ca/Des-Moines-Hotels-Hyatt-Place-West-Des-Moines-Jordan-Creek.h16112546.Hotel-Information) ![Quality Inn & Suites Des Moines - Merle Hay Road](https://images.trvl-media.com/lodging/1000000/10000/9700/9664/257ab000_y.jpg) ### Quality Inn & Suites Des Moines - Merle Hay Road 10/10 Excellent "Breakfast was good love their biscuits so soft & moist. The room was nice, clean, and spacious bed was very comfortable." [](https://expedia.ca/Des-Moines-Hotels-Quality-Inn-Suites.h9664.Hotel-Information) ![Drury Inn & Suites West Des Moines](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/2af2a76d_y.jpg) ### Drury Inn & Suites West Des Moines 10/10 Excellent "The location was great." [](https://expedia.ca/Des-Moines-Hotels-Drury-Inn-Suites-West-Des-Moines.h1836184.Hotel-Information) ![Hotel Fort Des Moines, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/9e4e0ef2_y.jpg) ### Hotel Fort Des Moines, Curio Collection by Hilton 10/10 Excellent "Comfy and stylish lobby and rooms, delicious cafe" [](https://expedia.ca/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) ![Motel 6 West Des Moines, IA](https://images.trvl-media.com/lodging/1000000/990000/986100/986072/e3428772_y.jpg) ### Motel 6 West Des Moines, IA 10/10 Excellent "Room clean & nice" [](https://expedia.ca/Des-Moines-Hotels-Motel-6-West-Des-Moines.h986072.Hotel-Information) ![Sonesta Essential Des Moines](https://images.trvl-media.com/lodging/1000000/60000/50800/50789/9b65231b_y.jpg) ### Sonesta Essential Des Moines 10/10 Excellent "Yes" [](https://expedia.ca/Des-Moines-Hotels-Sonesta-Essential-Des-Moines.h50789.Hotel-Information) ![AmericInn by Wyndham Des Moines Airport](https://images.trvl-media.com/lodging/1000000/860000/856000/855969/6f15108b_y.jpg) ### AmericInn by Wyndham Des Moines Airport 10/10 Excellent "Room was clean enough " [](https://expedia.ca/Des-Moines-Hotels-AmericInn-By-Wyndham-Des-Moines-Airport.h855969.Hotel-Information) ![Comfort Inn & Suites Event Center](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/a41cce84_y.jpg) ### Comfort Inn & Suites Event Center 10/10 Excellent "Helpful front desk. Nice room but the toilet is very low to the ground! Hard on my knees!" 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