Title: Book the Best Depew SPA Resorts from CA $158 - Spa Hotels in Depew, NY | Expedia.ca

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## Check availability on Depew Spa Hotels

Tonight

[Apr 8 - Apr 9](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-08&endDate=2026-04-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 9 - Apr 10](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-09&endDate=2026-04-10&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-10&endDate=2026-04-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-17&endDate=2026-04-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Depew hotels with a spa

![2 restaurants, dinner served](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/c468db44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/f6195d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/14f70c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/bde63631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Delavan Hotel & Spa

[](https://www.expedia.ca/Buffalo-Hotels-The-Delavan-Hotel-Spa.h15031117.Hotel-Information)

Bowmansville

9.0/10

Wonderful

(999 reviews)

- Luxurious spa retreat with rejuvenating massage services and modern fitness centre awaits at this upscale hotel near Walden Galleria Mall.

CA $139

CA $158 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/Buffalo-Hotels-The-Delavan-Hotel-Spa.h15031117.Hotel-Information)

![Couples treatment rooms, body treatments, hot stone massages](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/c1a06a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/2a49ee3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/680cb22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served, seafood](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/69eab7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

[](https://www.expedia.ca/Buffalo-Hotels-The-Mosey-Buffalo-Williamsville.h6290133.Hotel-Information)

Buffalo

9.4/10

Exceptional

(1,001 reviews)

- Rejuvenate in this upscale Williamsville hotel where a full-service spa and indoor pool create a haven for relaxation.

CA $200

CA $227 total

includes taxes & fees

Apr 26 - Apr 27

[](https://www.expedia.ca/Buffalo-Hotels-The-Mosey-Buffalo-Williamsville.h6290133.Hotel-Information)

![Hot stone massages, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/dd3fc86a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/aba5ffc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/0539858c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hot springs](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/f730f1f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Curtiss Hotel, an Ascend Collection Hotel

[](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information)

Downtown Buffalo

9.4/10

Exceptional

(1,001 reviews)

- Luxuriate in this hotel's rejuvenating full-service spa with hot stone massages and natural hot springs in the heart of downtown Buffalo.

CA $317

CA $371 total

includes taxes & fees

Apr 9 - Apr 10

[](https://www.expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-22&endDate=2026-04-23&regionId=6338362&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Choose what matters most at spa hotels in Depew

Pool

Breakfast included

Hot tub

4 stars

5 stars

## Top Depew Hotel Reviews

![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg)

### M Hotel Buffalo

10/10 Excellent

"The Staff Was Quite Accommodating During My Stay"

[](https://expedia.ca/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information)

![Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/ee46454f_y.jpg)

### Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2/10 Terrible

"Clean rooms, friendly staff, good wifi, but the breakfast was terrible. Me and my girlfriend got food poisoning. They really need to step up their breakfast for a hotel. Overall 2.5/5 because of the breakfast. "

[](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information)

![Hyatt Place Buffalo/Amherst](https://images.trvl-media.com/lodging/10000000/9460000/9456500/9456445/5bccc2ed_y.jpg)

### Hyatt Place Buffalo/Amherst

10/10 Excellent

"Hotel is beautiful well maintained friendly staff beautiful rooms "

[](https://expedia.ca/Buffalo-Hotels-Hyatt-Place-BuffaloAmherst.h9456445.Hotel-Information)

![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50_y.jpg)

### Buffalo Airport Hotel

8/10 Good

"Rooms were clean"

[](https://expedia.ca/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information)

![Sleep Inn & Suites Buffalo Airport](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3_y.jpg)

### Sleep Inn & Suites Buffalo Airport

6/10 Okay

"We were told our room would be ready in 45 minutes and when we came back they told us it still wasn't ready. After my Husband got upset they ended up switching us to a room that was ready across the hall. We don't know why it took my husband getting upset for them to not have done that in the first place."

[](https://expedia.ca/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information)

![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg)

### Garden Place Hotel

8/10 Good

"Spacious room,comfy bed nice size hot tub and shower."

[](https://expedia.ca/Buffalo-Hotels-Garden-Place-Hotel.h1060721.Hotel-Information)

## Frequently asked questions

### Looking for a spa hotel in Depew?

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### What is a Depew spa hotel?

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