Title: Book the Best De Soto FAMILY FRIENDLY Hotels from CA $86 - Kid-Friendly Hotels in De Soto, MO | Expedia.ca [Hotels in De Soto](https://expedia.ca/De-Soto-Hotels.d6085105.Travel-Guide-Hotels)[Vacation Rentals in De Soto](https://expedia.ca/De-Soto-Vacation-Rentals.d6085105.Travel-Guide-VacationRentals)[De Soto Car Rentals](https://expedia.ca/Car-Rentals-In-De-Soto.d6085105.Car-Rental-Guide)[De Soto Vacation Packages](https://expedia.ca/De-Soto.d6085105.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/1f71f3ee006639c0d49d18546ddf62b5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jessica King # Find Family Hotels in De Soto, MO from CA $86 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on De Soto Family Hotels Tonight [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-10-22&endDate=2025-10-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Tomorrow [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6085105&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) ## Top De Soto Family Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d234bb55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/5d1ea140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/3a2c35d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e565804d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Farmington Farmington 8.0/10 Very good (597) "Clean, friendly staff, quiet" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacy CA $76 CA $86 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/f4d876e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/c41116cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/7e9b49ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont Inn and Suites by Wyndham Farmington, MO Farmington 8.0/10 Very good (1001) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $79 CA $89 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/fc42ec39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/705e1bff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/4d9ecdd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Festus - St Louis South Festus 7.8/10 Good (895) "The stay and food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ricky CA $112 CA $131 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/d33a8d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/d7498121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/ef39d78c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/da3a948f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Arnold Arnold 9.2/10 Wonderful (1015) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $126 CA $146 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/2dd0e783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/59299cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/2993d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/7df3af01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Farmington by IHG Farmington 8.6/10 Excellent (410) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carole CA $132 CA $373 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Suites-Farmington.h1095128.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/a7778b87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/3ac9f95d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/b11945d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/15d7a42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Arnold Arnold 9.6/10 Exceptional (1009) "Great and friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $172 CA $199 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/3eea0c0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/9eacdd77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/2f521851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/w3839h2584x0y3-9df926a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Farmington Farmington 8.8/10 Excellent (507) "Had a very nice stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $160 CA $182 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Farmington-Hotels-Hampton-Inn-Farmington.h3594547.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/68000000/67680000/67672200/67672168/b4be75d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/68000000/67680000/67672200/67672168/56b30b13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/68000000/67680000/67672200/67672168/b56eb1ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/68000000/67680000/67672200/67672168/49f831a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peter Ray House Maeystown 10/10 Exceptional (70) "The house was wonderful, the town was delightful, and the people were very friendly! We can’t wait for our next trip!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $189 CA $315 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Maeystown-Hotels-Peter-Ray-House.h67672168.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/40607ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/77f907ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/09284110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/18500/18482/d69a5751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Farmington Farmington 7.6/10 Good (847) "We loved it and we are still staying " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dustin CA $73 CA $87 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Farmington-Hotels-Quality-Inn-Farmington.h18482.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/a5b7d625.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/61bc5568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/a80c5b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/f209698b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Three bedroom home in Central Farmington Farmington 9.6/10 Exceptional (29) "Was in town for a junior golf tournament and this place we perfect! Very clean, updated and comfortable. Nice quiet neighborhood. Would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason K. CA $151 CA $343 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Farmington-Hotels-Cozy-Three-Bedroom-Home-In-Central-Farmington.h100830468.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-05&endDate=2025-11-06®ionId=6085105&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top De Soto Hotel Reviews ![Comfort Inn Festus - St Louis South](//images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc_y.jpg) ### Comfort Inn Festus - St Louis South 10/10 Excellent " Mika went above and beyond even getting us ice when we checked in. As I was checking out Gary fell out used.Mika got him up and inside. Got ice and bandages. We were soon on our way." [](https://expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Drury Inn & Suites St. Louis Arnold](//images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/a7778b87_y.jpg) ### Drury Inn & Suites St. Louis Arnold 10/10 Excellent "Great and friendly staff!" [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) ![Pear Tree Inn St. Louis Arnold](//images.trvl-media.com/lodging/1000000/50000/40200/40112/d33a8d98_y.jpg) ### Pear Tree Inn St. Louis Arnold 10/10 Excellent "Clean with free breakfast-about what you'd expect. They do have snacks and a soda fountain during happy hour and the soda is available til 10pm (free). We have stayed here before and will always try to stay here when the price is right. " [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](//images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 10/10 Excellent " Clean rooms,breakfast " [](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![Baymont Inn and Suites by Wyndham Farmington, MO](//images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg) ### Baymont Inn and Suites by Wyndham Farmington, MO 10/10 Excellent "Everyone was very thoughtful and the room was excellent. Great place to stay !!!!!" [](https://expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Super 8 by Wyndham Farmington](//images.trvl-media.com/lodging/1000000/860000/855800/855747/d234bb55_y.jpg) ### Super 8 by Wyndham Farmington 10/10 Excellent "Its ok for price" [](https://expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) ![Super 8 by Wyndham Potosi](//images.trvl-media.com/lodging/1000000/160000/158800/158717/2cf60fb9_y.jpg) ### Super 8 by Wyndham Potosi 10/10 Excellent "The desk clerk went above and beyond. All of the non-smoking rooms were sold out online but he made sure I had one! The check-in process was very easy and the staff was very friendly! Would highly recommend." [](https://expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information) ![Quality Inn Farmington](//images.trvl-media.com/lodging/1000000/20000/18500/18482/40607ed2_y.jpg) ### Quality Inn Farmington 10/10 Excellent "We loved it and we are still staying " [](https://expedia.ca/Farmington-Hotels-Quality-Inn-Farmington.h18482.Hotel-Information) ![Super 8 by Wyndham Bonne Terre](//images.trvl-media.com/lodging/1000000/860000/856300/856283/4bc8c9bd_y.jpg) ### Super 8 by Wyndham Bonne Terre 10/10 Excellent "Rooms were clean, staff was very friendly. " [](https://expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Bonne-Terre.h856283.Hotel-Information) ## Frequently asked questions ### What's De Soto like for family-friendly vacations? > The destination of De Soto is a great choice if you've been thinking about a vacation with your kids. The restaurants here makes this an attractive vacation spot for families. Arrange a flight into St. Louis, MO (SUS-Spirit of St. Louis), which is located 36.5 mi (58.8 km) from the city center. ### When's the best time to book a family-friendly vacation in De Soto? > The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches. ### What's there to see and do with your family in De Soto? > While you are visiting De Soto, you might want to round up the kiddos and make time to see interesting attractions such as Redfield's Flea Market, Bonne Terre Mine, and Festus Public Library. 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