Book The Best Hotels in Cross Keys, MO for 2026 from CA $102 - Fully Refundable Options

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Our top choices for Cross Keys hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

1. Pear Tree Inn St. Louis Airport

St. Ann

Darren

CA $125

CA $147 total

includes taxes & fees

Sep 2 - Sep 3

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern lobby with blue seating, a reception desk, and large windows.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

2. Hyatt Select St. Louis Airport

Woodson Terrace

Paige

CA $152

CA $187 total

includes taxes & fees

Sep 6 - Sep 7

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A pool area with two hot tubs, seating, and a view of the outdoors.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

3. Drury Inn & Suites St. Louis Airport

Edmundson

Robert

CA $159

CA $187 total

includes taxes & fees

Sep 6 - Sep 7

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

4. Wingate by Wyndham St. Louis Airport

St. Ann

Margaret

CA $153

CA $180 total

includes taxes & fees

Sep 6 - Sep 7

A snack kiosk with a variety of packaged foods and beverages, a cash register, and a sign reading 'The Shop.'

A hotel with a clear sky, parking lot, and a sign for the Hilton Garden Inn.

A lobby with a fireplace, seating area, and a large framed artwork.

A spacious indoor area with multiple dining tables and chairs, a fireplace, and a large artwork on the wall.

5. Hilton Garden Inn St. Louis Airport

Berkeley

Darryl

CA $195

CA $228 total

includes taxes & fees

Sep 6 - Sep 7

A modern living room with a sofa set, two armchairs, a coffee table, and a wall art piece.

A hotel reception area with a wooden reception desk, a blue wall with a MainStay Suites sign, and artwork depicting bridges.

A snack display in a store with various packaged snacks and beverages.

6. Comfort Inn St. Louis Airport

Bridgeton

Crystal

CA $110

CA $132 total

includes taxes & fees

Sep 6 - Sep 7

A Holiday Inn Express & Suites building with a covered entrance, stone pillars, and a landscaped area in front.

An indoor swimming pool with clear water, surrounded by tiled walls and a brick floor.

A hotel lobby with a reception desk, seating area, and a large decorative wall.

A breakfast buffet with labeled sections for fruit and cereal.

7. Holiday Inn Express & Suites St Louis Airport by IHG

Woodson Terrace

Misty

CA $163

CA $201 total

includes taxes & fees

Sep 13 - Sep 14

An indoor swimming pool with a high ceiling, surrounded by seating areas and potted plants.

An aerial view of a large building with a parking lot and a road adjacent to it.

A bar area with a beverage dispenser, a variety of liquor bottles, and bar stools.

8. The Great Rivers, an Ascend Collection Hotel

Alton

Elizabeth

CA $122

CA $139 total

includes taxes & fees

Sep 27 - Sep 28

A hotel lobby with a tiled floor, white columns, a reception desk, and a view into the dining area.

A modern hotel room with a large bed, bedside lamps, a desk, and a chair.

A spacious lobby with a reception desk, seating area, and a large window.

A two-story house with a tiled roof, a covered porch, and a driveway leading to the entrance.

9. Motel 6 Hazelwood, MO

Hazelwood

Gwen

CA $84

CA $102 total

includes taxes & fees

Sep 1 - Sep 2

A buffet with fruits, pastries, and beverages.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

10. Renaissance St. Louis Airport Hotel

Berkeley

Arnetta

CA $176

CA $206 total

includes taxes & fees

Sep 10 - Sep 11

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

11. Hampton Inn & Suites St. Louis at Forest Park

Dogtown

CA $192

CA $226 total

includes taxes & fees

Sep 4 - Sep 5

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

A spacious dining area with high tables and booths, large windows, and a view of greenery outside.

A hotel room with a large bed, two bedside tables, a desk, and a chair.

A reception area with two dark wooden reception desks, a stone-textured wall, and a sign reading "Comfort INN".

12. Comfort Inn Edwardsville - St. Louis

Edwardsville

Mihai

CA $134

CA $154 total

includes taxes & fees

Sep 6 - Sep 7

A modern dining area with a long table, colorful chairs, and decorative hanging lights.

A hotel room with two beds, a flat-screen TV, a microwave, and a desk with a chair.

A Hampton Inn & Suites hotel with a modern design, featuring a large entrance and a well-lit facade.

A hotel reception area with a counter, a poster, and a patterned carpet.

13. Hampton Inn & Suites St. Louis/Alton

Alton

Kristen

CA $181

CA $206 total

includes taxes & fees

Sep 7 - Sep 8

A modern lobby with a fireplace, comfortable seating, and a large TV screen.

A compact living space with a kitchenette, a flat-screen TV, a desk with a chair, a bench, and a sofa.

A Best Western Plus hotel with a modern brick facade, large glass windows, and a covered entrance area.

A hotel room with a large bed, two bedside tables with lamps, a wooden headboard, and a framed picture on the wall.

14. Best Western Plus St. Louis West-Westport

Westport

Klara

CA $122

CA $142 total

includes taxes & fees

Aug 30 - Aug 31

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A modern hotel with a prominent Hilton sign, a Hampton Inn by Hilton sign, and a parking lot with a covered area and landscaped beds.

15. Hampton Inn By Hilton St Louis Airport

Woodson Terrace

Carrie

CA $185

CA $221 total

includes taxes & fees

Sep 7 - Sep 8

A breakfast bar with a coffee machine, a bowl of fruit, and a clock on the wall.

A compact hotel room with a kitchenette, a sofa bed, a flat-screen TV, and a window with curtains.

A compact living area with a sofa, a small table, and a kitchenette in the background.

16. MainStay Suites St Louis Airport

Bridgeton

Eliezer

CA $125

CA $149 total

includes taxes & fees

Aug 30 - Aug 31

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

A hotel room with a large bed, a desk, a chair, and a television.

A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to an upper level.

An indoor swimming pool with clear glass walls, a tiled edge, and a ceiling with metal beams. There are lounge chairs and tables around the pool area.

17. Drury Inn & Suites St. Louis Collinsville

Eastport

James

CA $154

CA $177 total

includes taxes & fees

Sep 2 - Sep 3

The Clayton Plaza Hotel sign with a stone wall and plants in front.

A hotel room with two beds, a desk, a chair, and a television.

A lobby with a chandelier, a round table with a floral arrangement, and a painting on the wall.

18. Clayton Plaza Hotel & Extended Stay

Clayton

Gail

CA $129

CA $151 total

includes taxes & fees

Aug 30 - Aug 31

A brick building with a wooden gazebo in front.

A spacious dining area with multiple round tables and chairs, a fireplace, and large windows with curtains.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

A compact kitchen with a sink, microwave, and stove, a wooden cabinet, and a television mounted on the wall.

19. Country Hearth Inn & Suites Edwardsville St. Louis

Edwardsville

les

CA $151

CA $174 total

includes taxes & fees

Aug 30 - Aug 31

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

20. Hilton St. Louis Airport

Woodson Terrace

Tony

CA $198

CA $236 total

includes taxes & fees

Sep 6 - Sep 7

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Top Cross Keys Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

"This property was very clean, staff was very kind and friendly. The continental breakfast was definitely better than most and they have a shuttle to and from the airport that runs 24 hours a day every 20 minutes that is free for guests. Will definitely stay here again."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"C"

Hilton St. Louis at the Ballpark

8/10 Good

"Our room was over $300 a night and it had paint chipping everywhere and needed repairs. It was clean just out of date."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"The room was cozy and the location was great"

The Royal Sonesta Chase Park Plaza St. Louis

10/10 Excellent

"This is a great historic hotel. Although some the bars and ballrooms from the early heyday have been renovated or repurposed, you can still admire some opulent architectural elements from the 1920s. Sonesta has done a great job bringing the property into the present while maintaining the beauty of its past. On a Saturday night, I walked by the vibrant and packed Chase Club that seemed to have a big following for karaoke and watched the Odyssey in one of the lobby's six theaters. The Chase is still the place in St. Louis."

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"Clean room, great staff! Love it here, but DO NOT stay on the 17th floor. It is under the 24hr gym and the 2 HUGE suites, that seem to party all noght long, lol. Not fun to wake up all the time because of that! Last year we were on the 14th floor and it was amazing! Pool table, shuffleboard, great bar/restaurant! Beautiful place!"

Forest Park Hotel by MDR

8/10 Good

"Free parking, clean big room, with microwave and fridge and affordable."

More cheap stays in Cross Keys

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO

CA $84

CA $102 total

Sep 1 - Sep 2

includes taxes & fees

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO

CA $94

CA $109 total

Aug 31 - Sep 1

includes taxes & fees

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL

CA $111

CA $125 total

Aug 31 - Sep 1

includes taxes & fees

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

CA $125

CA $147 total

Sep 2 - Sep 3

includes taxes & fees

9.2/10 Wonderful! (3,206 reviews)

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

CA $135

CA $158 total

Sep 7 - Sep 8

includes taxes & fees

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO

CA $147

CA $168 total

Sep 7 - Sep 8

includes taxes & fees

8/10 Very good! (1,001 reviews)

Hotels in Cross Keys with star rating

Frequently asked questions

Where is the best place to stay in Cross Keys?

Located 10.8 mi (17.4 km) from the heart of Cross Keys, Hyatt Regency St. Louis at The Arch is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Clayton Plaza Hotel & Extended Stay and Hollywood Casino & Hotel St. Louis. See all available top hotels, or vacation rentals in Cross Keys.

What are some of the best vacation home rentals in Cross Keys?

4BR 2BA Modern Family Home with Private Heated Inground Pool Open March 1-Nov11: This vacation home rental near Cross Keys offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation. See all vacation rentals in Cross Keys.

If I need to cancel my hotel reservation in Cross Keys, will I receive a refund?

Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cross Keys.

What is staying in Cross Keys like?

Travelers to Cross Keys will find plenty to explore and enjoy. Around the area, top sights include St. Louis Zoo, St. Louis Union Station, and Gateway Arch. There are 1924 hotels and other accommodations in the surrounding area. Find out more about Cross Keys.

What is there to see in Cross Keys?

Notable places to visit in the wider area include St. Louis Zoo, St. Louis Union Station, and Gateway Arch. Additionally, you'll find Busch Stadium in the area. Check out what more to see and do in Expedia's Cross Keys guide.

What's the seasonal weather like in Cross Keys?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Cross Keys is 52 inches.

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Find hotels in Cross Keys, MO from CA $102

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Cross Keys

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Cross Keys hotels

1. Pear Tree Inn St. Louis Airport

2. Hyatt Select St. Louis Airport

3. Drury Inn & Suites St. Louis Airport

4. Wingate by Wyndham St. Louis Airport

5. Hilton Garden Inn St. Louis Airport

6. Comfort Inn St. Louis Airport

7. Holiday Inn Express & Suites St Louis Airport by IHG

8. The Great Rivers, an Ascend Collection Hotel

9. Motel 6 Hazelwood, MO

10. Renaissance St. Louis Airport Hotel

11. Hampton Inn & Suites St. Louis at Forest Park

12. Comfort Inn Edwardsville - St. Louis

13. Hampton Inn & Suites St. Louis/Alton

14. Best Western Plus St. Louis West-Westport

15. Hampton Inn By Hilton St Louis Airport

16. MainStay Suites St Louis Airport

17. Drury Inn & Suites St. Louis Collinsville

18. Clayton Plaza Hotel & Extended Stay

19. Country Hearth Inn & Suites Edwardsville St. Louis

20. Hilton St. Louis Airport

Top Cross Keys Hotel Reviews

Pear Tree Inn St. Louis Airport

Drury Plaza Hotel St. Louis at the Arch

Hilton St. Louis at the Ballpark

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

The Royal Sonesta Chase Park Plaza St. Louis

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Forest Park Hotel by MDR

More cheap stays in Cross Keys

Motel 6 Hazelwood, MO

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Best Western St. Louis Fairview Heights

Pear Tree Inn St. Louis Airport

Tru By Hilton St. Louis Downtown

Hampton Inn St. Charles St. Peters

Hotels in Cross Keys with star rating

Frequently asked questions

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