Title: Book the Best BUSINESS Hotels in Colleton River Plantation in 2026 | Expedia.ca [Vacation Rentals in Bluffton](https://expedia.ca/Bluffton-Vacation-Rentals.d602237.Travel-Guide-VacationRentals)[Flights to Bluffton](https://expedia.ca/Cheap-Flights-To-Bluffton.d602237.Travel-Guide-Flights)[Colleton River Plantation Car Rentals](https://expedia.ca/Car-Rentals-In-Colleton-River-Plantation.d553248635976478635.Car-Rental-Guide)[Colleton River Plantation Vacations](https://expedia.ca/Colleton-River-Plantation.d553248635976478635.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Colleton River Plantation, SC from CA $120 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Colleton River Plantation Business Hotels Tonight [Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=553248635976478635&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=553248635976478635&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976478635&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976478635&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Colleton River Plantation business-friendly hotels ![Outdoor pool, open 8:00 AM to midnight, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/1044657d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Boating](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/f5922dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand, beach volleyball, beach bar](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/2fa63c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach bar](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/07770e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beach House Resort Hilton Head [](https://www.expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) South End 8.8/10 Excellent (1001) "Clean room , friendly staff, great beach access " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theodore CA $149 CA $221 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/0a636c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/0cec8e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/15b290ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/c4b23ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Sea Island Inn [](https://www.expedia.ca/Beaufort-Hotels-Best-Western-Sea-Island-Inn.h16225.Hotel-Information) Historic District 9.4/10 Exceptional (1001) "Perfect spot!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tricia CA $192 CA $211 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Beaufort-Hotels-Best-Western-Sea-Island-Inn.h16225.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/7000000/6880000/6874100/6874010/63cb7bb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Private kitchen](https://images.trvl-media.com/lodging/7000000/6880000/6874100/6874010/85ab7620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/7000000/6880000/6874100/6874010/1c8449ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6880000/6874100/6874010/6ad8acaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DeSoto Beach Hotel [](https://www.expedia.ca/Tybee-Island-Hotels-DeSoto-Beach-Hotel.h6874010.Hotel-Information) South Beach 8.4/10 Very good (1000) "The room, parking, front desk, location, Continental Breakfast, and even the partial ocean view were all perfect!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vesta CA $129 CA $159 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Tybee-Island-Hotels-DeSoto-Beach-Hotel.h6874010.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/484680bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, aromatherapy, manicures and pedicures, massages](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/ac59f880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/e398b7e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/59893002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Beachfront Resort & Spa Hilton Head Island [](https://www.expedia.ca/Hilton-Head-Hotels-Marriott-Hilton-Head-Resort-Spa.h583363.Hotel-Information) Mid Island 8.4/10 Very good (1395) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ngone Lon CA $191 CA $263 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Hilton-Head-Hotels-Marriott-Hilton-Head-Resort-Spa.h583363.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e21613a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/d41a41f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast on weekends](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/f635c09e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, free beach shuttle](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/20abed49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hilton Head Island by IHG [](https://www.expedia.ca/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) South End 8.4/10 Very good (337) "The clean room and location was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ROBERT CA $123 CA $135 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/220ad345.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/4065fcc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/w3837h2561x3y0-d0889314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/e369fde7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Resort Hilton Head Island [](https://www.expedia.ca/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) South End 8.6/10 Excellent (1180) "Beautiful area and the hotel staff were so friendly. Would love to stay for several days! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hannah CA $233 CA $321 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/afa1c93c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/b827ff63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/w3840h2558x0y0-48c05050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/2382de78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Beaufort, SC [](https://www.expedia.ca/Beaufort-Hotels-Tru-By-Hilton-Beaufort.h49284680.Hotel-Information) Beaufort 9.0/10 Wonderful (709) "Awesome stay!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $134 CA $148 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Beaufort-Hotels-Tru-By-Hilton-Beaufort.h49284680.Hotel-Information) ![3 outdoor pools, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/c13a70d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/a66caa26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/aced1e4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/4e548057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Hilton Head Oceanfront Resort [](https://www.expedia.ca/Hilton-Head-Hotels-Omni-Hilton-Head-Oceanfront-Resort.h14690.Hotel-Information) Mid Island 9.0/10 Wonderful (1002) "Entire property clean and in awesome shape- All staff were extremely helpful and polite!! Wonderful amenities and the nicest beach on the east coast!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $241 CA $330 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/Hilton-Head-Hotels-Omni-Hilton-Head-Oceanfront-Resort.h14690.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/13000/12919/b7b092da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13000/12919/c39af7ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/13000/12919/121212b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/13000/12919/bf8c56c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Beaufort [](https://www.expedia.ca/Beaufort-Hotels-SpringHill-Suites-By-Marriott-Beaufort.h12919.Hotel-Information) Beaufort 9.4/10 Exceptional (1021) "Have stayed there twice and had great stays both time. Staff is the best! Clean, quiet and comfortable. Will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $142 CA $156 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Beaufort-Hotels-SpringHill-Suites-By-Marriott-Beaufort.h12919.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1150000/1141400/1141317/a49fdacd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1150000/1141400/1141317/w3836h2551x4y3-fd5087a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1150000/1141400/1141317/f05125bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1141400/1141317/21f596ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Bluffton Hilton Head Island [](https://www.expedia.ca/Bluffton-Hotels-Spark-By-Hilton-Bluffton-Hilton-Head-Island.h1141317.Hotel-Information) Belfair 8.4/10 Very good (151) "Nice hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $109 CA $120 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/Bluffton-Hotels-Spark-By-Hilton-Bluffton-Hilton-Head-Island.h1141317.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-30&endDate=2025-12-31®ionId=553248635976478635&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Colleton River Plantation Hotel Reviews ![Holiday Inn Express Bluffton at Hilton Head Area by IHG](https://images.trvl-media.com/lodging/1000000/900000/892200/892177/bf3e7e4b_y.jpg) ### Holiday Inn Express Bluffton at Hilton Head Area by IHG 10/10 Excellent "The room was clean, and there was spacious parking. I highly recommend staying here." [](https://expedia.ca/Hilton-Head-Hotels-Holiday-Inn-Express-Bluffton-At-Hilton-Head-Area.h892177.Hotel-Information) ![Sonesta Resort Hilton Head Island](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/220ad345_y.jpg) ### Sonesta Resort Hilton Head Island 10/10 Excellent "The resort is very clean and well maintained. Lots of seating areas to have conversations. The outdoor hot tub was warm, gentle, and relaxing. There was also relaxing music playing. There are two pools one for families and another for adults. The beach is just steps away. You can rent a bike at the resort and head to the beach for a ride. It is $30 for 1 hour or $35 for 4 hours. The room was a nice comfortable size. We had a resort view, while not being ocean front was still a good view. We ordered breakfast in the restaurant and it was delicious! " [](https://expedia.ca/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) ![Palmera Inn and Suites](https://images.trvl-media.com/lodging/1000000/570000/564600/564590/28eae64d_y.jpg) ### Palmera Inn and Suites 10/10 Excellent "Very nice staff" [](https://expedia.ca/Hilton-Head-Hotels-Palmera-Inn-And-Suites.h564590.Hotel-Information) ![Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG](https://images.trvl-media.com/lodging/2000000/1650000/1647600/1647509/80bdfa73_y.jpg) ### Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG 10/10 Excellent "Everything was so perfect , clean rooms , hospitality was exceptional would definitely recommend and come again. The management was awesome " [](https://expedia.ca/Beaufort-Hotels-Holiday-Inn-Hotel-Suites-Beaufort-At-Highway-21.h1647509.Hotel-Information) ![Beach House Resort Hilton Head](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/b454fbd2_y.jpg) ### Beach House Resort Hilton Head 10/10 Excellent "Great access to the beach and the Tikihut and like music was fun" [](https://expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) ![The Westin Hilton Head Island Resort & Spa](https://images.trvl-media.com/lodging/1000000/30000/22200/22170/2c505874_y.jpg) ### The Westin Hilton Head Island Resort & Spa 10/10 Excellent "Beautiful room. Ocean view. The hotel was magical " [](https://expedia.ca/Hilton-Head-Hotels-The-Westin-Hilton-Head-Island-Resort-Spa.h22170.Hotel-Information) ![Red Roof Inn Hardeeville](https://images.trvl-media.com/lodging/2000000/1260000/1256400/1256324/cb6dafc3_y.jpg) ### Red Roof Inn Hardeeville 10/10 Excellent "Staff was polite and quickly got me checked in and gave me all the information needed to find my room. Room was very clean. Bed was comfortable, the water was warm and had pressure. Even though this hotel is right off the highway it was quiet. Would stay again when traveling through the area. " [](https://expedia.ca/Hilton-Head-Hotels-Red-Roof-Inn-Hardeeville.h1256324.Hotel-Information) ![Montage Palmetto Bluff](https://images.trvl-media.com/lodging/2000000/1110000/1105600/1105531/1c8012e6_y.jpg) ### Montage Palmetto Bluff 10/10 Excellent "Beautiful resort with much to do! Accommodations are beautiful and Excellent hospitality too." [](https://expedia.ca/Hilton-Head-Hotels-Montage-Palmetto-Bluff.h1105531.Hotel-Information) ![Spark By Hilton Hilton Head Island](https://images.trvl-media.com/lodging/13000000/12430000/12427700/12427670/35eaaa78_y.jpg) ### Spark By Hilton Hilton Head Island 10/10 Excellent "No beach view " [](https://expedia.ca/Hilton-Head-Hotels-Best-Western-Ocean-Breeze-Inn.h12427670.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in Windmill Harbor ](https://www.expedia.ca/4Star-Windmill-Harbor-Hotels.s40-0-d553248635975850995.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Colleton River ](https://www.expedia.ca/5Star-Colleton-River-Bluffton-Hotels.s50-n553248635976469811-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Westbury Park ](https://www.expedia.ca/5Star-Westbury-Park-Bluffton-Hotels.s50-n553248635976474845-0.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Belfair ](https://www.expedia.ca/Belfair-Bluffton-Hotels-All-Inclusive-Hotel.0-n553248635976480986-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - 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