Title: Hotels by Best Western in Clemson from CA $131 | Expedia.ca [Clemson Travel Guide](https://expedia.ca/Clemson.dx6594)[Hotels in Clemson](https://expedia.ca/Clemson-Hotels.d6594.Travel-Guide-Hotels)[Vacation Rentals in Clemson](https://expedia.ca/Clemson-Vacation-Rentals.d6594.Travel-Guide-VacationRentals)[Flights to Clemson](https://expedia.ca/Cheap-Flights-To-Clemson.d6594.Travel-Guide-Flights)[Things to do in Clemson](https://expedia.ca/Things-To-Do-In-Clemson.d6594.Travel-Guide-Activities)[Clemson Car Rentals](https://expedia.ca/Car-Rentals-In-Clemson.d6594.Car-Rental-Guide)[Clemson Vacation Packages](https://expedia.ca/Clemson.d6594.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/37a5b84dadafa74cfb0eac38a6f52509.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Best Western in Clemson from CA $131 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 17 - Nov 18](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2025-11-17&endDate=2025-11-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 18 - Nov 19](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2025-11-18&endDate=2025-11-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Clemson Best Western Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson Seneca 8.4/10 Very good (631) "Convenient for Clemson visits." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen CA $119 CA $131 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-01&endDate=2025-12-02®ionId=6594&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FClemson-Hotels-Best-Western.0-0-d6594--bBestWestern.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FClemson-Hotels-Best-Western.0-0-d6594--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Clemson Hotel Reviews ### Quality Inn Seneca Clemson Area US-123 10/10 Excellent "Clean room w fridge and microwave Comfy bed" [](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ### Microtel Inn & Suites by Wyndham Anderson/Clemson 10/10 Excellent "Room was clean, staff was nice! " [](https://expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ### The Abernathy of Clemson 10/10 Excellent "Room was large, clean and updated with all amenities. Staff was nice " [](https://expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ### Days Inn by Wyndham Anderson 10/10 Excellent "Everytime I book a room with Days Inn I alway walk into a good smelling clean room. Any problems that I might have if I ever do they don’t hesitate to fix the problem right away. They serve a free breakfast every morning from 6am to 9am that’s very good. Sam and his staff are great when it comes to good customer service as well… they treat you like family all the time. " [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Loved the hotel. Very clean and the staff was great. Location was amazing right downtown of Clemson. Amazing and would stay there again." [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ### Clemson University's James F. Martin Inn 10/10 Excellent "P place to stay! Love it" [](https://expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ### Baymont by Wyndham Easley/Greenville 10/10 Excellent "It wasn't great, but it was better than the other 2 cheaper options on town. Breakfast of eggs, sausage, make your own waffle, yogurt, bagels, etc... small TV in the room." [](https://expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ### Comfort Inn & Suites Clemson - University Area 10/10 Excellent "The hotel was amazing with the exception of the front desk clerk. She was rude." [](https://expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ### Inn @ Clemson 10/10 Excellent "Good" [](https://expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Best Western Hotels in Aiken](https://www.expedia.ca/Aiken-Hotels-Best-Western.0-0-d6058112--bBestWestern.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Beech Island](https://www.expedia.ca/Beech-Island-Hotels-Hilton-Hotels.0-0-d3000353088--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Brookhaven](https://www.expedia.ca/Brookhaven-Hotels-Motel-6.0-0-d553248635975852330--bMotel6.Travel-Guide-Filter-Hotels) - [Aparthotels in Central](https://www.expedia.ca/Central-Apart-Hotels.d10503-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Central](https://www.expedia.ca/Central-Bed-And-Breakfast.d10503-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Boutique Hotels in Central](https://www.expedia.ca/Central-Hotels-Boutique-Hotel.0-0-d10503-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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