Title: Book the Best Clarksdale LUXURY Hotels - Upscale Hotels in Clarksdale, MS | Expedia.ca

[Hotels in Clarksdale](https://expedia.ca/Clarksdale-Hotels.d6640.Travel-Guide-Hotels)[Vacation Rentals in Clarksdale](https://expedia.ca/Clarksdale-Vacation-Rentals.d6640.Travel-Guide-VacationRentals)[Flights to Clarksdale](https://expedia.ca/Cheap-Flights-To-Clarksdale.d6640.Travel-Guide-Flights)[Clarksdale Car Rentals](https://expedia.ca/Car-Rentals-In-Clarksdale.d6640.Car-Rental-Guide)[Clarksdale Vacation Packages](https://expedia.ca/Clarksdale.d6640.Destination-Travel-Guides)

![The home of the Delta Blues museum, the Crossroads, Ground Zero Blues club owned by Morgan Freeman and Reds blues club.  Several blues festivals in the city.  Great authentic blues can be found here.  ](https://images.trvl-media.com/place/6640/7baf9be0-ae17-4021-8d1e-fa3526070c6e.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Alice Andersen

![](https://images.trvl-media.com/place/6640/7baf9be0-ae17-4021-8d1e-fa3526070c6e.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check availability on Clarksdale Luxury Hotels

Tonight

[Feb 3 - Feb 4](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2026-02-03&endDate=2026-02-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2026-02-04&endDate=2026-02-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Clarksdale luxury hotels

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/d6d31cff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/e98cafb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/94b5934f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Clarksdale

[](https://www.expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information)

Clarksdale

7.4/10

Good

(714 reviews)

"The rooms could be a little more clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Courtney

CA $120

CA $131 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-17&endDate=2026-02-18&regionId=6640&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Clarksdale Hotel Reviews

![Quality Inn](https://images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07_y.jpg)

### Quality Inn

10/10 Excellent

"Evwrything was extremely excellent!!"

[](https://expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information)

## Frequently asked questions

### Which area of Clarksdale is best to stay in for luxury hotels?

> This central area is the heart of Clarksdale's cultural and entertainment offerings. It's very walkable, with restored historic buildings housing a selection of high-end accommodation options, blues clubs, and eateries. You'll find yourself close to landmarks like the Delta Blues Museum and the famous Crossroads sign.
> 
>   
> Couples looking for a refined experience will appreciate hotels in this area. They often feature comfortable rooms, on-site dining, and easy access to live music venues, making for a sophisticated and convenient stay.

### How much does a luxury hotel in Clarksdale cost?

### How can I save on a luxury hotel in Clarksdale with Expedia?

### Is it cheaper to book a luxury Clarksdale hotel and flights as a package?

### Can I cancel my luxury hotel reservation on Expedia?

## Explore a world of travel with Expedia

- Lodging
- Flights
- Packages
- Cars
- More ways to book

- [2 Star Hotels in Lyon ](https://www.expedia.ca/2Star-Lyon-Hotels.s20-0-d553248634998705303.Travel-Guide-Filter-Hotels)
- [Alligator Hotels ](https://www.expedia.ca/Alligator-Hotels.d553248635975866196.Travel-Guide-Hotels)
- [Villas in Alligator ](https://www.expedia.ca/Alligator-Villas.d553248635975866196-aaVillas.Travel-Guide-Accommodation)
- [Cheap Hotels in Batesville ](https://www.expedia.ca/Batesville-Hotels-Cheap-Hotels.0-0-d6711-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Batesville ](https://www.expedia.ca/Batesville-Hotels-Luxury-Hotel.0-0-d6711-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Batesville ](https://www.expedia.ca/Batesville-Hotels-Pet-Friendly-Hotel.0-0-d6711-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Batesville Hotels ](https://www.expedia.ca/Batesville-Hotels.d6711.Travel-Guide-Hotels)
- [Hotels near Bologna Performing Arts Center ](https://www.expedia.ca/Bologna-Performing-Arts-Center-Hotels.0-l553248621532644997-0.Travel-Guide-Filter-Hotels)
- [Charleston Hotels ](https://www.expedia.ca/Charleston-Hotels.d553248634999355364.Travel-Guide-Hotels)
- [Aparthotels in Cleveland ](https://www.expedia.ca/Cleveland-Apart-Hotels.d7485-aaApartHotels.Travel-Guide-Accommodation)
- [B&B in Cleveland ](https://www.expedia.ca/Cleveland-Bed-And-Breakfast.d7485-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Guest Houses in Cleveland ](https://www.expedia.ca/Cleveland-Guest-Houses.d7485-aaGuestHouses.Travel-Guide-Accommodation)
- [Boutique Hotels in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Boutique-Hotel.0-0-d7485-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
- [Golf Hotels in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Golf-Hotel.0-0-d7485-tGolfHotel.Travel-Guide-Filter-Hotels)
- [Historic Hotels in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Historic-Hotel.0-0-d7485-tHistoricHotel.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Hotel-With-Pool.0-0-d7485-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Hotels with Bar in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Hotels-With-Bar.0-0-d7485-tHotelswithBar.Travel-Guide-Filter-Hotels)
- [Hotels with Free Parking in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Hotels-With-Free-Parking.0-0-d7485-tHotelswithFreeParking.Travel-Guide-Filter-Hotels)
- [Hotels with smoking rooms in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Hotels-With-Smoking-Rooms.0-0-d7485-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels)
- [Lgbt Friendly Hotels in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-LGBT-Friendly-Hotel.0-0-d7485-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Luxury-Hotel.0-0-d7485-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Shopping Hotels in Cleveland ](https://www.expedia.ca/Cleveland-Hotels-Shopping-Hotel.0-0-d7485-tShoppingHotel.Travel-Guide-Filter-Hotels)
- [Cleveland Hotels ](https://www.expedia.ca/Cleveland-Hotels.d7485.Travel-Guide-Hotels)
- [Motels in Cleveland ](https://www.expedia.ca/Cleveland-Motels.d7485-aaMotels.Travel-Guide-Accommodation)
- [Coahoma Hotels ](https://www.expedia.ca/Coahoma-Hotels.d553248634998790329.Travel-Guide-Hotels)
- [Farmstay in Courtland ](https://www.expedia.ca/Courtland-Agritourism.d553248635975870279-aaAgritourism.Travel-Guide-Accommodation)
- [Cheap Hotels in Courtland ](https://www.expedia.ca/Courtland-Hotels-Cheap-Hotels.0-0-d553248635975870279-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Courtland ](https://www.expedia.ca/Courtland-Hotels-Hotel-With-Pool.0-0-d553248635975870279-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Courtland Hotels ](https://www.expedia.ca/Courtland-Hotels.d553248635975870279.Travel-Guide-Hotels)
- [Hotels near Delta State University ](https://www.expedia.ca/Delta-State-University-Hotels.0-l6092579-0.Travel-Guide-Filter-Hotels)
- [Tunica County Hotels ](https://www.expedia.ca/Destinations-In-Tunica-County.d553248635083907330.Hotel-Destinations)
- [B&B in Duncan ](https://www.expedia.ca/Duncan-Bed-And-Breakfast.d553248635149961086-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Guest Houses in Duncan ](https://www.expedia.ca/Duncan-Guest-Houses.d553248635149961086-aaGuestHouses.Travel-Guide-Accommodation)
- [Hostels in Duncan ](https://www.expedia.ca/Duncan-Hostels.d553248635149961086-aaHostels.Travel-Guide-Accommodation)
- [Luxury Hotels in Duncan ](https://www.expedia.ca/Duncan-Hotels-Luxury-Hotel.0-0-d553248635149961086-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Duncan Hotels ](https://www.expedia.ca/Duncan-Hotels.d553248635149961086.Travel-Guide-Hotels)
- [Motels in Duncan ](https://www.expedia.ca/Duncan-Motels.d553248635149961086-aaMotels.Travel-Guide-Accommodation)
- [Guest Houses in Dundee ](https://www.expedia.ca/Dundee-Guest-Houses.d6342839-aaGuestHouses.Travel-Guide-Accommodation)
- [Family Hotels in Dundee ](https://www.expedia.ca/Dundee-Hotels-Family-Hotel.0-0-d6342839-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Dundee ](https://www.expedia.ca/Dundee-Hotels-Pet-Friendly-Hotel.0-0-d6342839-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Dundee Hotels ](https://www.expedia.ca/Dundee-Hotels.d6342839.Travel-Guide-Hotels)
- [Motels in Dundee ](https://www.expedia.ca/Dundee-Motels.d6342839-aaMotels.Travel-Guide-Accommodation)
- [B&B in Enid ](https://www.expedia.ca/Enid-Bed-And-Breakfast.d3000444128-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Enid Hotels ](https://www.expedia.ca/Enid-Hotels.d3000444128.Travel-Guide-Hotels)
- [B&B in Lula ](https://www.expedia.ca/Lula-Bed-And-Breakfast.d183462-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Cheap Hotels in Lula ](https://www.expedia.ca/Lula-Hotels-Cheap-Hotels.0-0-d183462-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Lula Hotels ](https://www.expedia.ca/Lula-Hotels.d183462.Travel-Guide-Hotels)
- [Rv Parks in Lula ](https://www.expedia.ca/Lula-RV-Parks.d183462-aaRVParks.Travel-Guide-Accommodation)
- [Villas in Lula ](https://www.expedia.ca/Lula-Villas.d183462-aaVillas.Travel-Guide-Accommodation)
- [B&B in Lyon ](https://www.expedia.ca/Lyon-Bed-And-Breakfast.d553248634998705303-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Marks Hotels ](https://www.expedia.ca/Marks-Hotels.d553248634998851595.Travel-Guide-Hotels)
- [Mound Bayou Hotels ](https://www.expedia.ca/Mound-Bayou-Hotels.d553248635975851069.Travel-Guide-Hotels)
- [Vacation Homes in Mound Bayou ](https://www.expedia.ca/Mound-Bayou-Private-Vacation-Homes.d553248635975851069-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Pope Hotels ](https://www.expedia.ca/Pope-Hotels.d553248635928598869.Travel-Guide-Hotels)
- [Lodges in Pope ](https://www.expedia.ca/Pope-Lodges.d553248635928598869-aaLodges.Travel-Guide-Accommodation)
- [Renova Hotels ](https://www.expedia.ca/Renova-Hotels.d553248634998825816.Travel-Guide-Hotels)
- [Guest Houses in Rosedale ](https://www.expedia.ca/Rosedale-Guest-Houses.d3000444248-aaGuestHouses.Travel-Guide-Accommodation)
- [Luxury Hotels in Rosedale ](https://www.expedia.ca/Rosedale-Hotels-Luxury-Hotel.0-0-d3000444248-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Rosedale Hotels ](https://www.expedia.ca/Rosedale-Hotels.d3000444248.Travel-Guide-Hotels)
- [Business Hotels in Sardis ](https://www.expedia.ca/Sardis-Hotels-Business-Hotel.0-0-d9750-tBusinessHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Sardis ](https://www.expedia.ca/Sardis-Hotels-Cheap-Hotels.0-0-d9750-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Apartments in Shelby ](https://www.expedia.ca/Shelby-Apartments.d553248634999000962-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Shelby ](https://www.expedia.ca/Shelby-Condos.d553248634999000962-aaCondos.Travel-Guide-Accommodation)
- [Shelby Hotels ](https://www.expedia.ca/Shelby-Hotels.d553248634999000962.Travel-Guide-Hotels)
- [Motels in Tunica County ](https://www.expedia.ca/Tunica-County-Motels.d553248635083907330-aaMotels.Travel-Guide-Accommodation)
- [Resorts in Tunica County ](https://www.expedia.ca/Tunica-County-Resort-Hotels.d553248635083907330-aaResortHotels.Travel-Guide-Accommodation)
- [Business Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-Business-Hotel.0-0-d55209-tBusinessHotel.Travel-Guide-Filter-Hotels)
- [Caesars Entertainment Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-Caesars-Entertainment.0-0-d55209--bCaesarsEntertainment.Travel-Guide-Filter-Hotels)
- [Casino Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-Casino-Hotel.0-0-d55209-tCasinoHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-Cheap-Hotels.0-0-d55209-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in Tunica ](https://www.expedia.ca/Tunica-Hotels-Couples-Resorts-Hotels.0-0-d55209-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [Golf Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-Golf-Hotel.0-0-d55209-tGolfHotel.Travel-Guide-Filter-Hotels)
- [La Quinta Inn & Suites Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-La-Quinta-Inn-Suites.0-0-d55209--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-Luxury-Hotel.0-0-d55209-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Tunica ](https://www.expedia.ca/Tunica-Hotels-Pet-Friendly-Hotel.0-0-d55209-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Tunica Hotels ](https://www.expedia.ca/Tunica-Hotels.d55209.Travel-Guide-Hotels)
- [Motels in Tunica ](https://www.expedia.ca/Tunica-Motels.d55209-aaMotels.Travel-Guide-Accommodation)
- [Resorts in Tunica ](https://www.expedia.ca/Tunica-Resort-Hotels.d55209-aaResortHotels.Travel-Guide-Accommodation)
- [Tutwiler Hotels ](https://www.expedia.ca/Tutwiler-Hotels.d553248635975846728.Travel-Guide-Hotels)
- [Cheap Hotels in Webb ](https://www.expedia.ca/Webb-Hotels-Cheap-Hotels.0-0-d553248635975871263-tCheapHotels.Travel-Guide-Filter-Hotels)

- [Flights to Tunica ](https://www.expedia.ca/Cheap-Flights-To-Tunica.d55209.Travel-Guide-Flights)
- [Flights from Rosedale ](https://www.expedia.ca/lp/flights/3000444248/flights-from-rosedale)
- [Flights from Pope ](https://www.expedia.ca/lp/flights/553248635928598869/flights-from-pope)
- [Flights from Crowder ](https://www.expedia.ca/lp/flights/553248635975869385/flights-from-crowder)
- [Flights from Dundee ](https://www.expedia.ca/lp/flights/6342839/flights-from-dundee)
- [Flights from Cleveland ](https://www.expedia.ca/lp/flights/7485/flights-from-cleveland)
- [Flights from Daytona Beach (DAB) to Tunica (UTM) ](https://www.expedia.ca/lp/flights/dab/utm/daytona-beach-to-tunica)
- [Flights from Detroit (DTW) to Tunica (UTM) ](https://www.expedia.ca/lp/flights/dtw/utm/detroit-to-tunica)
- [Flights from Greenville (GSP) to Tunica (UTM) ](https://www.expedia.ca/lp/flights/gsp/utm/greenville-to-tunica)
- [Flights from St. Louis (STL) to Tunica (UTM) ](https://www.expedia.ca/lp/flights/stl/utm/st-louis-to-tunica)
- [Flights from Toronto (YYZ) to Tunica (UTM) ](https://www.expedia.ca/lp/flights/yyz/utm/toronto-to-tunica)

- [Hambone Art Gallery ](https://www.expedia.ca/Hambone-Art-Gallery-Clarksdale.d553248621561877046.Vacation-Attraction)
- [Rock N' Roll & Blues Heritage Museum ](https://www.expedia.ca/Rock-N-Roll-Blues-Heritage-Museum-Clarksdale.d553248621533115347.Vacation-Attraction)

- [Ace New Zealand Rental Cars in Marks ](https://www.expedia.ca/ACE-New-Zealand-Car-Rentals-In-Marks.d553248634998851595-c1106.Car-Rental-Guide-Suppliers)
- [Alamo Rent A Car Rental Cars in Ruleville ](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Ruleville.d553248634998643340-c6.Car-Rental-Guide-Suppliers)
- [Car rental Cleveland ](https://www.expedia.ca/Car-Rentals-In-Cleveland.d7485.Car-Rental-Guide)
- [Car rental Lula ](https://www.expedia.ca/Car-Rentals-In-Lula.d183462.Car-Rental-Guide)
- [Rental cars Tunica Municipal airport ](https://www.expedia.ca/Car-Rentals-In-Tunica-Municipal.d6129470.Car-Rental-Guide)
- [Car rental Tunica ](https://www.expedia.ca/Car-Rentals-In-Tunica.d55209.Car-Rental-Guide)
- [Car rentals in Sixt Freilassing, Mnchener Str. 53 ](https://www.expedia.ca/Sixt-at-Freilassing.v55209.Car-Rental-Guide-Location)

- [Book Luxury Hotels in Clarksdale on Expedia.com ](https://www.expedia.com/Clarksdale-Hotels-Luxury-Hotel.0-0-d6640-tLuxuryHotel.Travel-Guide-Filter-Hotels)