Title: Book the Best BUSINESS Hotels in Clarksdale in 2025 | Expedia.ca [Hotels in Clarksdale](https://expedia.ca/Clarksdale-Hotels.d6640.Travel-Guide-Hotels)[Vacation Rentals in Clarksdale](https://expedia.ca/Clarksdale-Vacation-Rentals.d6640.Travel-Guide-VacationRentals)[Flights to Clarksdale](https://expedia.ca/Cheap-Flights-To-Clarksdale.d6640.Travel-Guide-Flights)[Clarksdale Car Rentals](https://expedia.ca/Car-Rentals-In-Clarksdale.d6640.Car-Rental-Guide)[Clarksdale Vacation Packages](https://expedia.ca/Clarksdale.d6640.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/3e4a4f54528b1ae1cd0c50edfbcf03ce.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Molly Bond # Find Business Hotels in Clarksdale, MS from CA $116 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Clarksdale Business Hotels Tonight [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2025-10-17&endDate=2025-10-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2025-10-18&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6640&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Clarksdale Business Hotels ![Reception](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/de175126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/84d69b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/20bde9f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Clarksdale Clarksdale 8.2/10 Very good (324) "We would stay there again." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew Ray CA $183 CA $200 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/e3029007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Smoking | Room amenity](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/09f42bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Smoking](https://images.trvl-media.com/lodging/1000000/160000/151300/151226/2606ec8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn & Suites Clarksdale Clarksdale 5.8/10 (392) "The employees were very friendly " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa CA $107 CA $116 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/980000/979400/979308/9b0e70d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/980000/979400/979308/33ab3d7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/980000/979400/979308/9af9566e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/979400/979308/f73e6725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cleveland by IHG Cleveland 7.8/10 Good (917) "I like the location " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $167 CA $183 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-Holiday-Inn-Express-Hotel-Suites-Cleveland.h979308.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-31&endDate=2025-11-01®ionId=6640&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Clarksdale Hotel Reviews ![Americas Best Value Inn & Suites Clarksdale](//images.trvl-media.com/lodging/1000000/160000/151300/151226/c0e992b8_y.jpg) ### Americas Best Value Inn & Suites Clarksdale 10/10 Excellent "The employees were very friendly " [](https://expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information) ![Hampton Inn Clarksdale](//images.trvl-media.com/lodging/9000000/8280000/8273700/8273622/e34ceb08_y.jpg) ### Hampton Inn Clarksdale 10/10 Excellent "The staff was so pleasant and friendly The entire visit was very nice " [](https://expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information) ![Quality Inn](//images.trvl-media.com/lodging/1000000/160000/151300/151227/766fdf07_y.jpg) ### Quality Inn 10/10 Excellent "Quiet and comfortable " [](https://expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Clarksdale cost? > Business-friendly hotels in Clarksdale range between CA $116 and CA $200 per night. This means you can lock in a property with perks like WiFi and workspaces at a price that's easy on your wallet. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the best business-friendly hotels in Clarksdale? > Corporate travellers recommend [Hampton Inn Clarksdale](https://www.expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information). This 2.5-stars property offers amenities such as a swimming pool and laundry services. [The Holy Moly Blues Central](https://www.expedia.ca/Clarksdale-Hotels-The-Holy-Moly-Blues-Central.h12028767.Hotel-Information) is another popular option for a work trip. It has a 3-stars rating and conveniences like individually decorated rooms and a cafe. You can pick from multiple business-friendly hotels in Clarksdale that have a total average guest review rating of 7.2. ### How many business-friendly hotels are there in Clarksdale? > When work takes you to Clarksdale, you'll have 5 business-friendly hotels to choose from. These properties offer a well-suited location with the conveniences corporate travellers need. ### What are the best cheap business-friendly hotels in Clarksdale? > Save money on your work trip to Clarksdale by reserving one of our business-friendly hotels that start at CA $116 per night. One low-priced property is [Hampton Inn Clarksdale](https://www.expedia.ca/Clarksdale-Hotels-Hampton-Inn-Clarksdale.h8273622.Hotel-Information), which comes with amenities like a swimming pool and complimentary breakfast. [Quality Inn](https://www.expedia.ca/Clarksdale-Hotels-Quality-Inn.h151227.Hotel-Information) is another leading pick for corporate travellers with a tight budget. It features a swimming pool and WiFi. Don't forget to add some sightseeing to your Clarksdale work trip. Head out and discover a few fun and free attractions, such as [Rock N' Roll & Blues Heritage Museum](https://www.expedia.ca/Rock-N-Roll-Blues-Heritage-Museum-Clarksdale.d553248621533115347.Vacation-Attraction) and [Hambone Art Gallery](https://www.expedia.ca/Hambone-Art-Gallery-Clarksdale.d553248621561877046.Vacation-Attraction). This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the top business-friendly motels in Clarksdale? > [Americas Best Value Inn & Suites Clarksdale](https://www.expedia.ca/Clarksdale-Hotels-Americas-Best-Value-Inn-Suites-Clarksdale.h151226.Hotel-Information) is suited to both work and play. A terrace and an electric car charging station are among the many amenities at this business-friendly option, located around 2 kilometres south of central Clarksdale.When it's time to change from your work to casual attire and discover the sights, head straight to [The Holy Moly Theatre](https://www.expedia.ca/The-Holy-Moly-Theatre-Clarksdale.d553248621586301798.Vacation-Attraction). [New Roxy](https://www.expedia.ca/New-Roxy-Clarksdale.d553248621561877044.Vacation-Attraction) is another top attraction in Clarksdale. ### Why book your business-friendly hotel in Clarksdale with Expedia? > With useful amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly stays come with everything you'll need to settle that big contract — and then relax! Enter your destination and preferred travel dates and we'll help you plan everything else. ### How can I find cheap business-friendly hotels in Clarksdale? > When you're travelling for work in Clarksdale, our "business friendly" filter will help you find the right hotel. From fast WiFi to meeting rooms and workspaces, they come with the amenities you need to get the job done. Another tip? Refine your search by your preferred star rating and budget to view the most affordable accommodations. ### What is there to do in Clarksdale near my business-friendly hotel? > Clarksdale has enough sights to keep you on the go for weeks, starting with [The Holy Moly Theatre](https://www.expedia.ca/The-Holy-Moly-Theatre-Clarksdale.d553248621586301798.Vacation-Attraction). [New Roxy](https://www.expedia.ca/New-Roxy-Clarksdale.d553248621561877044.Vacation-Attraction), [Delta Blues Museum](https://www.expedia.ca/Delta-Blues-Museum-Clarksdale.d6263361.Vacation-Attraction) and [Rock and Blues Museum](https://www.expedia.ca/Rock-And-Blues-Museum-Clarksdale.d6263364.Vacation-Attraction) are other well-known attractions. If business is finished and you have time to spare, [Rock N' Roll & Blues Heritage Museum](https://www.expedia.ca/Rock-N-Roll-Blues-Heritage-Museum-Clarksdale.d553248621533115347.Vacation-Attraction) and [Hambone Art Gallery](https://www.expedia.ca/Hambone-Art-Gallery-Clarksdale.d553248621561877046.Vacation-Attraction) are worthwhile additions to your itinerary. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [2 Star Hotels in Lyon](https://www.expedia.ca/2Star-Lyon-Hotels.s20-0-d553248634998705303.Travel-Guide-Filter-Hotels) - [Alligator Hotels](https://www.expedia.ca/Alligator-Hotels.d553248635975866196.Travel-Guide-Hotels) - [Villas in Alligator](https://www.expedia.ca/Alligator-Villas.d553248635975866196-aaVillas.Travel-Guide-Accommodation) - [Cheap Hotels in Batesville](https://www.expedia.ca/Batesville-Hotels-Cheap-Hotels.0-0-d6711-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Batesville](https://www.expedia.ca/Batesville-Hotels-Luxury-Hotel.0-0-d6711-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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